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Optimizing reproductive health management in lupus and Sjogren's syndrome.
https://doi.org/10.1097/BOR.0000000000000839
Current Opinion in Rheumatology; Birru Talabi M, Himes KP et. al.

Sep 15th, 2021 - People with childbearing capacity who are diagnosed with systemic lupus erythematosus (SLE) and Sjogren's syndrome (SS) have specific and important reproductive health considerations. Recommendations from the European League Against Rheumatism (EULAR) and the American College of Rheumatology (ACR) provide rheumatologists and other clinicians with guidance for reproductive health management of p...

Long-term Blood Pressure Variability and Kidney Function in Participants of the ASPREE ...
https://doi.org/10.1093/ajh/hpab143
American Journal of Hypertension; Ernst ME, Fravel MA et. al.

Sep 15th, 2021 - Whether long-term blood pressure variability (BPV) predicts kidney function decline in generally healthy older adults is unknown. We investigated this association in ASPirin in Reducing Events in the Elderly (ASPREE) trial participants. Between 2010-2014, Australian and US individuals aged ≥70 years ( ≥65 if US minority) were recruited and followed with annual study visits for a median of 4.7 y...

Size-specific dose estimates of adult, chest computed tomography examinations: Comparis...
https://doi.org/10.1371/journal.pone.0257294
PloS One; Hu X, Gou J et. al.

Sep 14th, 2021 - This study aimed to compare the volume computed tomography dose index (CTDIvol), dose length product (DLP), and size-specific dose estimate (SSDE), with the China and updated 2017 American College of Radiology (ACR) diagnostic reference levels (DRLs) in chest CT examinations of adults based on the water-equivalent diameter (Dw). All chest CT examinations conducted without contrast administratio...

Toxic effects of subacute exposure to acrylamide on motor endplates of the gastrocnemiu...
https://doi.org/10.1016/j.tox.2021.152934
Toxicology Yanxian B, Gu Z et. al.

Sep 13th, 2021 - Acrylamide (ACR) is a recognized toxin that is known to induce neurotoxicity in humans and experimental animals. This study aimed to investigate the toxic effects of subacute exposure of the motor endplate (MEP) of the gastrocnemius in rats to ACR. All rats were randomly divided into control, 9, 18, and 36 mg/kg ACR groups, and ACR was administered by gastric gavage for 21 days. The behavioral ...

Response to: Correspondence on "European League Against Rheumatism (EULAR)/American Col...
https://doi.org/10.1136/annrheumdis-2021-221374
Annals of the Rheumatic Diseases; Aringer M, Costenbader K et. al.

Sep 13th, 2021 - Response to: Correspondence on "European League Against Rheumatism (EULAR)/American College of Rheumatology (ACR) SLE classification criteria item performance" by Aringer et al.|2021|Aringer M,Costenbader K,Leuchten N,Dörner T,Johnson SR,|

Body mass index trend and variability in rheumatoid arthritis.
https://doi.org/10.1007/s10067-021-05919-w 10.1016/j.metabol.2018.09.005 10.1016/j.semarthrit.2016.09.001 10.1186/s13075-015-0601-x 10.1002/art.20612 10.1001/archinte.165.14.1624 10.1002/acr.23258 10.1002/acr.22932 10.1002/acr.21710 10.1136/rmdopen-2017-000458 10.1002/art.1780310302 10.1136/annrheumdis-2019-216694 10.1093/rheumatology/keq199 10.1093/aje/kwq482 10.1097/01.mlr.0000182534.19832.83 10.1093/rheumatology/kes262 10.1038/ijo.2013.216 10.1186/1471-2458-13-889 10.1111/1753-6405.12804 10.1038/sj.ejcn.1601023 10.1002/acr.21627 10.3899/jrheum.141363 10.1056/NEJMoa1606148 10.1210/jc.2018-01239 10.1002/acr.24469 10.1002/art.20878
Clinical Rheumatology; Challener GJ, Myasoedova E et. al.

Sep 13th, 2021 - To characterize and compare trends in body mass index (BMI) and variability in BMI between subjects with rheumatoid arthritis (RA) and matched non-RA subjects and to determine predictors of BMI trends and variability within RA subjects. This retrospective population-based cohort study included 1114 Olmsted County, Minnesota residents, 558 with incident RA (age ≥ 18 years, 1987 ACR criteria met ...

Plasma exchange therapy in refractory inflammatory myopathy with anti-signal recognitio...
https://doi.org/10.1093/rheumatology/keab629
Rheumatology (Oxford, England); Zhang H, Sun Y et. al.

Sep 12th, 2021 - To explore the efficacy of plasma exchange (PE) therapy in refractory idiopathic inflammatory myopathy (IIM) patients with positive anti-signal recognition particle (SRP) antibody. Nine refractory IIM patients with positive anti-SRP antibody were enrolled, who received PE therapy at Ruijin Hospital from Octobor 2017 to December 2020. The clinical manifestations, laboratory tests, chest CT and l...

Systematic review of anti-dsDNA testing for systemic lupus erythematosus: A meta-analys...
https://doi.org/10.1016/j.autrev.2021.102943
Autoimmunity Reviews; Orme ME, Voreck A et. al.

Sep 12th, 2021 - The objective of this meta-analysis was to review the diagnostic performance of anti-dsDNA testing, to determine whether test specificity meets the revised 2019 EULAR/ACR classification criteria for systemic lupus erythematosus (SLE). The new criteria state that anti-dsDNA testing should be conducted using "an immunoassay with demonstrated ≥ 90% specificity for SLE against relevant disease cont...

Celebrating 40 years of the achievements of the American Association for Women Radiolog...
https://doi.org/10.1016/j.clinimag.2021.08.011
Clinical Imaging; DeBenedectis CM, Schmitt C et. al.

Sep 11th, 2021 - For the past 40 years the American Association for Women in Radiology (AAWR) has continued to support efforts to achieve its founding goals of improving the visibility of women in radiology, advancing the professional and academic standing of women in radiology, and identifying and addressing issues faced by women in radiology. In the past 5 years, the AAWR has made great strides to support wom...

Outcomes of screening mammography performed prior to fertility treatment in women ages ...
https://doi.org/10.1016/j.clinimag.2021.08.028
Clinical Imaging; Greenwood HI, Price ER et. al.

Sep 11th, 2021 - There are currently various conflicting recommendations for breast cancer screening with mammography in women between ages 40-49. There are no specific guidelines for breast cancer screening in women of this age group prior to assisted reproductive technology (ART) for the treatment of infertility. The purpose of our study was to evaluate outcomes of screening mammography, specifically ordered ...

Evaluating the performance of ACR, SLICC and EULAR/ACR classification criteria in child...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428110
Pediatric Rheumatology Online Journal; Abdwani R, Masroori E et. al.

Sep 11th, 2021 - The ACR 1997, SLICC 2012 and EULAR/ACR 2019 classification criteria were validated based on adult patients. To date, there are no classification criteria specific for children with SLE. The aim of the study is to compare the performance characteristics among the three SLE classification criteria (ACR-1997, SLICC-2012 and EULAR/ACR-2019) in childhood onset SLE (cSLE) cohort of Arab ethnicity fro...

Rate and predictors of chronic organ damage accrual in active lupus nephritis: a single...
https://www.ncbi.nlm.nih.gov/pubmed/34494962
Clinical and Experimental Rheumatology; Frontini G, Tamborini F et. al.

Sep 9th, 2021 - We aimed to identify the rates and predictors of chronic damage accrual and mortality in lupus nephritis (LN). We retrospectively measured SLICC/ACR Damage Index (SDI) in biopsy proven active LN with at least 5 years follow-up. We searched for the predictors of first SDI increase and death at univariate and multivariate regression analysis. Then, we considered clinical/biochemical/histological ...

Genome Transplant Dynamics
https://clinicaltrials.gov/ct2/show/NCT02423070

Sep 9th, 2021 - Acute rejection (AR) occurs within the first 6 months after transplantation in 20 percent of heart transplant patients and in 50 percent of lung-transplant patients. Given the often silent clinical presentation of AR, these patients require monitoring with repeated invasive and costly endomyocardial (EMB) or transbronchial biopsies (TBBx). Since organ transplantation is essentially genomic tran...

Can anticarbamylated protein antibodies be used to support the diagnosis of systemic lu...
https://doi.org/10.2217/bmm-2021-0037
Biomarkers in Medicine; Özdemir B, Erden A et. al.

Sep 8th, 2021 - Aim: Autoantibody development plays an important role in the pathogenesis of systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). In this study, we aimed to determine the diagnostic value of anticarbamylated protein antibody (anti-CarP) antibody in SLE and RA patients and its relationship with disease prognosis. Material & method: Fifty-seven SLE patients (F/M 50/7; median age 40.9...

Human myocardial mitochondrial oxidative capacity is impaired in mild acute heart trans...
https://doi.org/10.1002/ehf2.13607
ESC Heart Failure; Scheiber D, Zweck E et. al.

Sep 8th, 2021 - Acute cellular rejection (ACR) following heart transplantation (HTX) is associated with long-term graft loss and increased mortality. Disturbed mitochondrial bioenergetics have been identified as pathophysiological drivers in heart failure, but their role in ACR remains unclear. We aimed to prove functional disturbances of myocardial bioenergetics in human heart transplant recipients with mild ...

MabionCD20® Compared to MabThera® and Rituxan® in Patients With Rheumatoid Arthritis
https://clinicaltrials.gov/ct2/show/NCT04680962

Sep 8th, 2021 - Patients with active moderate-to-severe rheumatoid arthritis diagnosed according to the 2010 ACR criteria will be randomized to receive a blinded treatment course of either MabionCD20, EU-Rituximab (MabThera®) or US-Rituximab (Rituxan®) on the top of a stable methotrexate therapy. Two infusions of investigational drug at a dose of 1000 mg will be given at Day 1 and 15. Patients will be then fol...

Evaluation of microalbuminuria as a prognostic indicator after a TIA or minor stroke in...
https://doi.org/10.1136/bmjopen-2020-043253
BMJ Open; Strain WD, Elyas S et. al.

Sep 8th, 2021 - Transient ischaemic attacks (TIA) and minor strokes are important risk factors for further vascular events. We explored the role of albumin creatinine ratio (ACR) in improving risk prediction after a first event. Rapid access stroke clinics in the UK. 2202 patients attending with TIA or minor stroke diagnosed by the attending stroke physician, able to provide a urine sample to evaluate ACR usin...

Magnetic Resonance Imaging Phenotypes of Breast Cancer Molecular Subtypes: A Systematic...
https://doi.org/10.1016/j.acra.2021.07.017
Academic Radiology; Ab Mumin N, Ramli Hamid MT et. al.

Sep 6th, 2021 - Magnetic resonance imaging (MRI) is the most sensitive imaging modality in detecting breast cancer. The purpose of this systematic review is to investigate the role of human extracted MRI phenotypes in classifying molecular subtypes of breast cancer. We performed a literature search of published articles on the application of MRI phenotypic features in invasive breast cancer molecular subtype c...

Editorial Commentary: Anterior Cable Reconstruction for the Shoulder Superior Capsule: ...
https://doi.org/10.1016/j.arthro.2021.05.039
Arthroscopy : the Journal of Arthroscopic & Related Surge... Park MC

Sep 6th, 2021 - Anterior cable reconstruction (ACR) techniques for the superior capsule are multiple and varied. To optimize patient outcomes, technical considerations must be supported by basic science, both anatomically and biomechanically. ACR was designed to treat only partially repairable rotator cuff tendon tears, to provide a static support to a dynamic partial (and therefore "nonanatomic") repair, and ...