Sep 23rd, 2019 - David J. Amrol, MD reviewing Gabrielli S et al. J Allergy Clin Immunol Pract 2019 Sep/Oct
Sep 12th, 2019 - Aimmune Therapeutics, Inc. (Nasdaq:AIMT), a biopharmaceutical company developing treatments for potentially life-threatening food allergies, today announced that the Allergenic Products Advisory Committee (APAC) convened by the U.S. Food and Drug Administration (FDA) voted to support the use of AR101 (proposed trade name PALFORZIA™) in children and teens with peanut allergy. PALFORZIA is a comp...
Jul 31st, 2019 - Allergies can be life-threatening when they cause anaphylaxis, an extreme reaction with constriction of the airways and a sudden drop in blood pressure. Scientists have identified a subtype of immune cell that drives the production of antibodies (link is external) associated with anaphylaxis and other allergic reactions. The research was funded by the National Institute of Allergy and Infectio...
Sitton, C.,et al.
Dec 31st, 2017 - This article reviews the latest recommendations and clinical practice guidelines for peanut allergies among the pediatric population. Recommendations in this paper were compiled using information collected from a variety of publications of accredited professional organizations.
Oct 31st, 2015 - The Joint Task Force on Practice Parameters (JTF) is a 13-member task force consisting of 6 representatives assigned bythe American Academy of Allergy, Asthma & Immunology, 6 bythe American College of Allergy, Asthma & Immunology, and 1 bythe Joint Council of Allergy and Immunology. This JTF oversees thedevelopment of practice parameters, selects the workgroupchair(s), and reviews drafts of the.
Nov 30th, 2014 - This practice parameter is a joint effort between emergency physicians, who are often on the front line in the management ofanaphylaxis, and allergists-immunologists, who have a vested interest in how such patients are managed. As recognized by emergency physicians and allergists, the timely administration of epinephrine is essential to the effective treatment of anaphylaxis,and such administra.
Annals of Emergency Medicine; Barniol C, Dehours E et. al.
May 9th, 2017 - We evaluate the efficacy of a 4-day course of prednisone added to antihistamine for the management of acute urticaria in an emergency department (ED). In this double-blind randomized clinical trial, patients were eligible for inclusion if aged 18 years or older and with acute urticaria of no more than 24 hours' duration. Patients with anaphylaxis or who had received antihistamines or glucocorti...
Resuscitation Kawano T, Scheuermeyer FX et. al.
Jan 10th, 2017 - There is little data describing the differences in epinephrine (epi) administration and cardiac complications among older and younger patients with anaphylaxis. This retrospective cohort study was conducted at two urban emergency departments (ED) over a 5 year-period, and included adults who met a pre-specified criteria for anaphylaxis. Patients ≥50years of age were defined as "older". Univaria...
BMJ (Clinical Research Ed.); Turner PJ, Southern J et. al.
Dec 9th, 2015 - How safe is live attenuated influenza vaccine (LAIV), which contains egg protein, in young people with egg allergy? In this open label, phase IV intervention study, 779 young people (2-18 years) with egg allergy were recruited from 30 UK allergy centres and immunised with LAIV. The cohort included 270 (34.7%) young people with previous anaphylaxis to egg, of whom 157 (20.1%) had experienced res...
JAMA Wang C, Graham DJ et. al.
Nov 17th, 2015 - All intravenous (IV) iron products are associated with anaphylaxis, but the comparative safety of each product has not been well established. To compare the risk of anaphylaxis among marketed IV iron products. Retrospective new user cohort study of IV iron recipients (n = 688,183) enrolled in the US fee-for-service Medicare program from January 2003 to December 2013. Analyses involving ferumoxy...
Annals of Emergency Medicine; Grunau BE, Wiens MO et. al.
Mar 30th, 2015 - Corticosteroids (steroids) are often used to mitigate symptoms and prevent subsequent reactions in emergency department (ED) patients with allergic reactions, despite a lack of evidence to support their use. We sought to determine the association of steroid administration with improved clinical outcomes. Adult allergy-related encounters to 2 urban EDs during a 5-year period were identified and ...
The Journal of Pediatrics; Mehta H, Ramesh M et. al.
Jul 20th, 2014 - To examine the effects of food avoidance on the growth of children with food allergies. A retrospective chart review was performed for children with and without food allergies followed at 2 New York City general pediatric practices. Charts were selected based on codes from the International Classification of Diseases, 9th Revision, for well child visit, food allergy, anaphylaxis, and/or epineph...
The Journal of Allergy and Clinical Immunology; Ma L, Danoff TM et. al.
Dec 17th, 2013 - Anaphylaxis is a serious allergic reaction that can cause death; however, the actual risk of death is unclear. We sought to estimate the case fatality rate among hospitalizations or emergency department (ED) presentations for anaphylaxis and the mortality rate associated with anaphylaxis for the general population. This was a population-based epidemiologic study using 3 national databases: the ...
Annals of Emergency Medicine; Grunau BE, Li J et. al.
Nov 18th, 2013 - Allergic reactions are common presentations to the emergency department (ED). An unknown proportion of patients will develop biphasic reactions, and patients are often monitored for prolonged periods to manage potential reactions. We seek to determine the incidence of clinically important biphasic reactions. Consecutive adult patients presenting to 2 urban EDs with allergic reactions during a 5...
Stroke Lerario MP, Grotta JC et. al.
Sep 13th, 2019 - Background and Purpose- Allergic reactions, including anaphylaxis, can sometimes occur after intravenous thrombolysis in patients with acute ischemic stroke. However, it remains unclear whether patients with stroke who receive thrombolytic agents face a higher risk of anaphylaxis than those who do not receive thrombolytics. Methods- We performed a retrospective cohort study using inpatient and ...
Adrenaclick (epinephrine injection, USP auto-injector) is an emergency injection (shot) of epinephrine used for the treatment of life-threatening allergic reactions known as anaphylaxis. With numbered and color-coded instructions, Adrenaclick is designed for single-dose use by patients and caregivers in an anaphylactic
Adrenalin is a non-selective alpha and beta adrenergic agonist indicated for emergency treatment of allergic reactions (Type 1), including anaphylaxis.
Contraindications. Asclera® (polidocanol) Injection is contraindicated for patients with known allergy (anaphylaxis) to polidocanol and patients with acute vein and blood clotting diseases.
Find the official healthcare professional site of EpiPen® (epinephrine injection, USP) Auto-Injector, for the treatment of anaphylaxis. Read Important Safety Information.
Humalog U-200 should not be transferred from the Humalog KwikPen to a syringe as overdose and severe hypoglycemia can occur. Hypersensitivity Reactions: Severe, life-threatening, generalized allergy, including anaphylaxis, can occur with Humalog, Humalog Mix75/25, and Humalog Mix50/50. If hypersensitivity ...