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About 78,813 results

ALLMedicine™ Asthma Center

Research & Reviews  25,642 results

Biomarkers in asthma and allergic diseases.
https://doi.org/10.1111/cea.13988
Clinical and Experimental Allergy : Journal of the Britis... Shamji MH, Boyle RJ

Aug 3rd, 2021 - Biomarkers in asthma and allergic diseases.|2021|Shamji MH,Boyle RJ,|

A randomized controlled trial of glycopyrrolate administered by metered dose inhaler in...
https://doi.org/10.1080/02770903.2021.1938603
The Journal of Asthma : Official Journal of the Associati... Kerwin E, Dorinsky P et. al.

Aug 3rd, 2021 - To evaluate the efficacy and safety of three doses of glycopyrrolate metered dose inhaler (GP MDI) in patients with uncontrolled asthma despite treatment with inhaled corticosteroid/long-acting β2-agonists (ICS/LABA) with or without tiotropium, to...

Protective effect of sarsasapogenin in TNBS induced ulcerative colitis in rats associat...
https://doi.org/10.1080/08923973.2021.1955919
Immunopharmacology and Immunotoxicology; Mandlik DS, Mandlik SK et. al.

Aug 3rd, 2021 - Ulcerative colitis (UC) is a chronic inflammatory bowel condition considered by oxido-nitrosative stress and the release of pro-inflammatory cytokines that affects the mucosal lining of the colon. Sarsasapogenin (SG), as an active component, has b...

Mitochondrial ATP-Sensitive K+ Channel Opening Increased the Airway Smooth Muscle Cell ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289566
Canadian Respiratory Journal; Gao M, Sun Q et. al.

Aug 3rd, 2021 - Abnormal proliferation of airway smooth muscle cells (ASMCs) leads to airway remodeling and the development of asthma. This study aimed to assess whether mitochondrial ATP-sensitive K+ (mitoKATP) channels regulated the proliferation of ASMCs by re...

TH2 sensitization in the skin-gut-brain axis: How early-life Th2-mediated inflammation ...
https://doi.org/10.1111/pde.14657
Pediatric Dermatology; Jackson-Cowan L, Cole EF et. al.

Aug 3rd, 2021 - We recently reported children with comorbid atopic dermatitis (AD), asthma, allergic rhinitis, and food allergies displaying a 2.7-fold increase in developmental delays.2 To this end, we hypothesize unregulated increases in T helper-2 (Th2)-driven...

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Guidelines  35 results

Managing Asthma in Adolescents and Adults: 2020 Asthma Guideline Update From the Nation...
https://doi.org/10.1001/jama.2020.21974
JAMA Cloutier MM, Dixon AE et. al.

Dec 4th, 2020 - Asthma is a major public health problem worldwide and is associated with excess morbidity, mortality, and economic costs associated with lost productivity. The National Asthma Education and Prevention Program has released the 2020 Asthma Guideline...

Implementation of the Addendum Guidelines for Peanut Allergy Prevention by US allergist...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590504
The Journal of Allergy and Clinical Immunology; Johnson JL, Gupta RS et. al.

Aug 4th, 2020 - In 2017, the Addendum Guidelines for the Prevention of Peanut Allergy were published with recommendations on early introduction of peanut-containing foods based on infants' clinical history. We sought to conduct a nationwide US survey to assess Gu...

Adult Patients with Respiratory Distress: Current Evidence-based Recommendations for Pr...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390576
The Western Journal of Emergency Medicine; Hodroge SS, Glenn M et. al.

Jul 30th, 2020 - We developed evidence-based recommendations for prehospital evaluation and treatment of adult patients with respiratory distress. These recommendations are compared with current protocols used by the 33 local emergency medical services agencies (L...

Considerations on biologicals for patients with allergic disease in times of the COVID-...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300800
Allergy Vultaggio A, Agache I et. al.

Jun 6th, 2020 - The outbreak of the SARS-CoV-2-induced coronavirus disease 2019 (COVID-19) pandemic re-shaped doctor-patient interaction and challenged capacities of healthcare systems. It created many issues around the optimal and safest way to treat complex pat...

Managing Chronic Cough Due to Asthma and NAEB in Adults and Adolescents: CHEST Guidelin...
https://doi.org/10.1016/j.chest.2019.12.021
Chest Côté A, Russell RJ et. al.

Jan 24th, 2020 - Asthma and non-asthmatic eosinophilic bronchitis (NAEB) are among the commonest causes of chronic cough in adults. We sought to determine the role of non-invasive measurements of airway inflammation, including induced sputum and fractional exhaled...

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Drugs  884 results see all →

Clinicaltrials.gov  1,828 results

Extension Study to Evaluate the Safety and Tolerability of Tezepelumab in Adults and Adolescents With Severe, Uncontrolled Asthma
https://clinicaltrials.gov/ct2/show/NCT03706079

May 8th, 2020 - Subjects who have not met investigational product discontinuation criteria and have attended the EOT visit in either study D5180C00007 or D5180C00009 will be offered the opportunity to consent for the Multicentre, Double-blind, Randomized, Paralle...

Preventing Asthma in High Risk Kids
https://clinicaltrials.gov/ct2/show/NCT02570984

May 6th, 2020 - Prevention/ Disease modification of asthma.

Study of Efficacy of Fevipiprant in Patients With Nasal Polyposis and Asthma
https://clinicaltrials.gov/ct2/show/NCT03681093

May 6th, 2020 - A Phase 3b Proof-of-Concept study to evaluate the ability of fevipiprant dose 1 and dose 2, compared with placebo, as add-on to nasal spray standard-of-care (SoC), in reducing endoscopic nasal polyp score in adult (≥ 18 years) patients with nasal ...

6-Minute Pegboard and Ring Test Unsupported Arm Function Exercise Test in Asthma Patients
https://clinicaltrials.gov/ct2/show/NCT03693664

May 5th, 2020 - Objective: The aim of the study was to evaluate the validity and reliability of the six-minute pegboard and ring test in patients with controlled and partially controlled asthma. Demographic information: Name, age, diagnosis, occupation, body weig...

Role of Genetic Factors in the Development of Lung Disease
https://clinicaltrials.gov/ct2/show/NCT00001532

May 4th, 2020 - This study is designed to evaluate genetic mechanisms of lung disease by surveying polymorphic genes involved in respiratory function and examining gene expression in the lung cells of individuals with pulmonary disease (e.g., alpha 1-antitrypsin ...

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News  3,045 results

Benralizumab Promising for Severe, Chronic Rhinosinusitis With Nasal Polyps
https://www.medscape.com/viewarticle/954835

Jul 15th, 2021 - Benralizumab (Fasenra) significantly reduced nasal polyp score (NPS) and average nasal blockage score (NBS) compared with placebo for patients with severe chronic rhinosinusitis with nasal polyps (CRSwNP) in a phase 3 trial. The randomized, multic...

Tezepelumab Reduces Asthma Exacerbation Rates by 56%
https://www.medscape.com/viewarticle/954777

Jul 14th, 2021 - The US Food and Drug Administration (FDA) has granted priority review for the biologic tezepelumab (AstraZeneca/Amgen) for treatment of severe asthma. The announcement was reported July 8, just days before the start of the European Academy of Alle...

Short-Acting Beta Agonist Overuse 'a Global Public Health Issue'
https://www.medscape.com/viewarticle/954587

Jul 11th, 2021 - About one third of asthma patients have high use of short-acting beta agonists (SABAs) in Europe across all severity levels, said Santiago Quirce, MD, PhD, with Hospital Universitario in Madrid, Spain. High use — defined as three or more canisters...

Dupilumab Safe, Effective in Kids 6-11 With Moderate-to-Severe Asthma
https://www.medscape.com/viewarticle/954586

Jul 10th, 2021 - Dupilumab (Dupixent, Sanofi and Regeneron) significantly reduced exacerbations compared with placebo in children ages 6-11 years who had moderate-to-severe asthma in a phase 3 trial. A fully human monoclonal antibody, dupilumab also improved lung ...

Fast Five Quiz: Severe Asthma Management
https://reference.medscape.com/viewarticle/951633

Jul 7th, 2021 - Asthma is a common, chronic inflammatory disorder of the airways characterized by shortness of breath, wheezing, coughing, chest tightness, variable airflow limitation, and tissue remodeling. Nearly 400 million people around the world have asthma,...

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Patient Education  91 results see all →