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About 5,380 results

ALLMedicine™ Allergic Asthma Center

Research & Reviews  1,862 results

Suppression of airway allergic eosinophilia by Hp-TGM, a helminth mimic of TGF-β.
https://doi.org/10.1111/imm.13528
Immunology Chauché C, Rasid O et. al.

Jun 28th, 2022 - Type 2-high asthma is a chronic inflammatory disease of the airways which is increasingly prevalent in countries where helminth parasite infections are rare, and characterized by T helper 2 (Th2)-dependent accumulation of eosinophils in the lungs....

Muscarinic Receptor Antagonism and Allergen Induced Airway Responses in Allergic Asthma...
https://doi.org/10.25011/cim.v45i2.38229
Clinical and Investigative Medicine. Medecine Clinique Et... Davis BE, Cropper KJ et. al.

Jun 27th, 2022 - The purpose of this scoping review was to identify existing clinical and basic science knowledge surrounding the effect of muscarinic receptor antagonism on allergen-induced airway responses to inform future clinical research in this area. Multipl...

Development of allergic asthma and changes of intestinal microbiota in mice under high ...
https://doi.org/10.1016/j.ecoenv.2022.113786
Ecotoxicology and Environmental Safety; Deng R, Ma P et. al.

Jun 24th, 2022 - In respiratory diseases, the induction of allergic asthma is one of the hottest issues of international concern. The adjuvant effect of air pollutants including nanoparticles (NPs) has be pointed out to facilitate the occurrence and development of...

Predictive biomarkers for response to omalizumab in patients with severe allergic asthm...
https://doi.org/10.1080/17476348.2022.2092100
Expert Review of Respiratory Medicine; Li Y, Li X et. al.

Jun 23rd, 2022 - Predicting omalizumab treatment response has been a challenge and significant aspect for selecting suitable severe allergic asthma patients for omalizumab use. To determine which domains of pretreatment baseline characteristics predict omalizumab ...

Effectiveness and Safety of Omalizumab in Children With Allergic Asthma.
https://clinicaltrials.gov/ct2/show/NCT05424523

Jun 21st, 2022 - This non-interventional, retrospective study aimed to assess the effectiveness and safety of omalizumab in children with allergic asthma in China, and described patient profiles and treatment patterns of omalizumab in real-world practice. This stu...

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Guidelines  3 results

EAACI Guidelines on Allergen Immunotherapy: House dust mite-driven allergic asthma.
https://doi.org/10.1111/all.13749
Allergy Agache I, Lau S et. al.

May 17th, 2019 - Allergen immunotherapy (AIT) has been in use for the treatment of allergic disease for more than 100 years. Asthma treatment relies mainly on corticosteroids and other controllers recommended to achieve and maintain asthma control, prevent exacerb...

Asthma management: A new phenotype-based approach using presence of eosinophilia and al...
https://doi.org/10.1111/all.13165
Allergy Terl M, Sedlák V et. al.

Mar 23rd, 2017 - Asthma is a heterogeneous disease. The Czech Pneumology and Allergology Societies commissioned 10 experts to review the literature and create joint national guidelines for managing asthma, reflecting this heterogeneity. The aim was to develop an e...

Recommendations for the standardization of clinical outcomes used in allergen immunothe...
https://doi.org/10.1111/all.12383
Allergy Pfaar O, Demoly P et. al.

Apr 26th, 2014 - Allergen immunotherapy (AIT) has been thoroughly documented in randomized controlled trials (RCTs). It is the only immune-modifying and causal treatment available for patients suffering from IgE-mediated diseases such as allergic rhinoconjunctivit...

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Drugs  15 results see all →

Clinicaltrials.gov  171 results

Effectiveness and Safety of Omalizumab in Children With Allergic Asthma.
https://clinicaltrials.gov/ct2/show/NCT05424523

Jun 21st, 2022 - This non-interventional, retrospective study aimed to assess the effectiveness and safety of omalizumab in children with allergic asthma in China, and described patient profiles and treatment patterns of omalizumab in real-world practice. This stu...

Impact of Sleep Duration on Immune Balance in Urban Children With Asthma
https://clinicaltrials.gov/ct2/show/NCT05420766

Jun 15th, 2022 - Urban children with asthma are at high risk for short sleep, due to an environment that jeopardizes sleep and asthma management. Further, this group suffers from altered immune balance, a key biological process contributing to individual differenc...

Anakinra as a Rescue Treatment for Allergic Inflammation
https://clinicaltrials.gov/ct2/show/NCT04035109

Jun 8th, 2022 - Asthma is an increasingly common chronic illness with higher rates of hospitalization for exacerbation than many other chronic conditions. In 2009, total asthma costs in the U.S. were estimated at $56 billion per year, and over half the overall as...

Efficacy and Safety Evaluation for the Treatment of HDM Induced Allergic Asthma and Rhinitis/Rhinoconjunctivitis
https://clinicaltrials.gov/ct2/show/NCT05400811

Jun 2nd, 2022 - Prospective multicenter randomized double-dummy clinical trial of three active treatment groups compared to one placebo group. The principal objective of the clinical trial is the determination of the efficacy and safety of subcutaneous immunother...

HDM and Silver Birch NAC Standardisation
https://clinicaltrials.gov/ct2/show/NCT05378594

May 31st, 2022 - Nasal allergen challenge (NAC) is a useful tool in the investigation of allergic rhinitis, including grass pollen-induced seasonal allergic rhinitis (hay fever). The investigators have experience in using NAC to investigate the clinical and immuno...

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News  99 results

NIAID trial to test asthma drug in disadvantaged urban children
https://www.mdedge.com/chestphysician/article/255181/asthma/niaid-trial-test-asthma-drug-disadvantaged-urban-children
Mark S. Lesney, PhD, MDedge News

Jun 3rd, 2022 - The Prevention of Asthma Exacerbations Using Dupilumab in Urban Children and Adolescents (PANDA) trial was launched in order to examine the effects of treatment on children with poorly controlled allergic asthma who live in low-income urban enviro.

NIAID Trial to Test Asthma Drug in Disadvantaged Urban Children
https://www.medscape.com/viewarticle/975035

Jun 3rd, 2022 - The Prevention of Asthma Exacerbations Using Dupilumab in Urban Children and Adolescents (PANDA) trial was launched in order to examine the effects of treatment on children with poorly controlled allergic asthma who live in low-income urban enviro...

Fast Five Quiz: How Much Do You Know About Allergic Asthma?
https://www.medscape.com/viewarticle/895678

Feb 9th, 2022 - Asthma is characterized by episodic reversible airway obstruction, increased bronchial reactivity, and airway inflammation. Complex interactions among inflammatory cells, their mediators, airway epithelium, smooth muscle, and the nervous system le...

Omalizumab curbs airway inflammation in severe asthma
https://www.mdedge.com/chestphysician/article/251380/asthma/omalizumab-curbs-airway-inflammation-severe-asthma
Heidi Splete, MDedge News

Feb 2nd, 2022 - Patients with severe asthma who were new to omalizumab showed significant clinical improvement after 2 weeks of treatment, according to data from a pilot study of 26 adults. Although omalizumab is approved for severe allergic asthma, not all patie.

Impact of Allergic Rhinitis and Asthma on COVID-19
https://www.medscape.com/viewarticle/962799

Nov 11th, 2021 - Takeaway Allergic rhinitis (AR; in all ages) and allergic or non-allergic asthma (in those aged <65 years) were associated with a lower risk of COVID-19 infection, but not with the severity and mortality of COVID-19. Asthma was linked to an increa...

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Patient Education  2 results see all →