ALLMedicine™ Complement Deficiencies Center
Research & Reviews 46 results
https://doi.org/10.1007/s10875-021-01066-8 10.1001/jama.2020.2648 10.15585/mmwr.mm6937e4 10.1016/S1473-3099(20)30120-1 10.1007/s10875-019-00737-x 10.1016/j.anai.2020.06.006 10.1111/pai.13322 10.1016/j.jaip.2020.11.006 10.1016/j.anai.2020.04.033 10.1016/j.jaip.2020.09.052 10.1016/j.jaip.2020.08.059 10.1016/j.jaci.2020.09.010 10.1016/j.anai.2020.08.017 10.1111/pai.13263 10.3389/fimmu.2020.596761 10.1016/j.jaci.2020.12.261 10.1186/s13223-021-00518-5 10.3389/fimmu.2020.614086 10.1016/j.jaip.2019.02.004 10.1016/j.jaip.2020.11.042 10.1016/j.jinf.2020.05.017 10.1056/NEJMoa2002032 10.1515/dx-2020-0046 10.1038/s41562-020-0928-4 10.1111/ene.14718 10.1177/0194599820926464 10.1016/j.heliyon.2020.e05684 10.1007/s00038-020-01390-7 10.1002/ppul.24991 10.1111/all.14452 10.1177/1203475420928375 10.1172/JCI140970 10.1126/science.abd4570 10.1542/peds.2020-0702 10.3389/fpubh.2020.00152 10.1371/journal.pone.0241827 10.1016/j.jaci.2020.04.013 10.3855/jidc.13840 10.1016/S2352-3026[20]30429-4 10.1093/cid/ciaa1488
Journal of Clinical Immunology; Goudouris ES, Pinto-Mariz F et. al.
Jun 25th, 2021 - There is still scarce data on SARS-CoV-2 infection in patients with Inborn Errors of Immunity (IEI) and many unresolved questions. We aimed to describe the clinical outcome of SARS-CoV-2 infection in Brazilian IEI patients and identify factors inf...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7703597
Journal of Immunology (Baltimore, Md. : 1950); Reese B, Silwal A et. al.
Nov 8th, 2020 - Preclinical studies demonstrated that complement promotes tumor growth. Therefore, we sought to determine the best target for complement-based therapy among common human malignancies. High expression of 11 complement genes was linked to unfavorabl...
https://doi.org/10.1080/10428194.2020.1832673
Leukemia & Lymphoma; Pan BH, Kong YL et. al.
Oct 17th, 2020 - Diffuse large B-cell lymphoma (DLBCL) is the most frequent type of lymphoma. Our retrospective study included 553 newly diagnosed DLBCL patients from May 2009 to October 2019. The relationships between hypogammaglobulinemia, hypocomplementemia and...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7513499
Pediatric Rheumatology Online Journal; Al-Shaikhly T, Hayward K et. al.
Sep 26th, 2020 - Acquired complement deficiency can occur in the setting of autoimmune syndromes, such as systemic lupus erythematosus (SLE), with very low or, occasionally, undetectable C3 levels. Based on inherited complement defects, patients with transiently l...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240913
BMC Infectious Diseases; Pletschette Z, De Groote E et. al.
May 22nd, 2020 - Neisseria meningitidis has rarely been described as an agent of necrotic soft tissue infection. We report a case of a septic shock with necrotizing cellulitis due to Neisseria meningitidis serogroup W, treated by urgent extensive surgical debridem...
Clinicaltrials.gov 1 results
https://clinicaltrials.gov/ct2/show/NCT02141516
Feb 15th, 2017 - The study aims at evaluating the safety and immunogenicity of rMenB+OMV NZ when administered to subjects from 2 to 17 years of age with increased risk of meningococcal disease because either of primary or secondary complement deficiencies or of as...
News 5 results
https://reference.medscape.com/viewarticle/897550_2
Jun 7th, 2018 - Risk factors for severe sepsis and septic shock include the following: Extremes of age (<10 years and >70 years) Primary diseases (eg, liver cirrhosis, alcoholism, diabetes, cardiopulmonary diseases, solid malignancy, and hematologic malignancy) I...
https://www.mdedge.com/infectiousdisease/article/103719/infectious-diseases/acip-recommends-changes-2016-adult-immunization
Deepak Chitnis
Oct 21st, 2015 - The Advisory Committee on Immunization Practices (ACIP) has unanimously approved a series of changes to the adult immunization schedule for several vaccines. The changes, which must next be approved by the director of the Centers for Disease Contr.
https://www.medscape.com/viewarticle/813066
Oct 23rd, 2013 - The Centers for Disease Control and Prevention's Advisory Committee on Immunization Practices (ACIP) voted today to recommend (13 yes, 1 no, 1 abstain) the meningococcal conjugate vaccine MenACWY-CRM (Menveo, Novartis Vaccines) for use in infants ...
https://www.staging.medscape.com/viewarticle/813066
Oct 23rd, 2013 - The Centers for Disease Control and Prevention's Advisory Committee on Immunization Practices (ACIP) voted today to recommend (13 yes, 1 no, 1 abstain) the meningococcal conjugate vaccine MenACWY-CRM (Menveo, Novartis Vaccines) for use in infants ...
https://www.medscape.com/viewarticle/920918_6
Conclusion There is a multitude of evidence that confirms the importance of complement system activation in bacterial meningitis. Patients with genetic complement deficiencies, and/or lower complement levels in the CSF tend to have favourable outc...
