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About 153 results

ALLMedicine™ Complement Deficiencies Center

Research & Reviews  53 results

Screening for Immunodeficiencies in Children With Invasive Pneumococcal Disease: Six-Ye...
https://doi.org/10.1097/INF.0000000000003554
The Pediatric Infectious Disease Journal; Bijker EM, Bateman EAL et. al.

Apr 15th, 2022 - A previous study showed that investigation of children with invasive pneumococcal disease (IPD) revealed an immunodeficiency in up to 10% of cases. Following this report, we implemented a protocol to investigate children with IPD, to assess the pr...

Complement Deficiencies
https://emedicine.medscape.com/article/135478-overview

Feb 15th, 2022 - Background The complement system is part of the innate immune system. The complement system plays an important part in defense against pyogenic organisms. It promotes the inflammatory response, eliminates pathogens, and enhances the immune respons...

Complement Deficiencies
http://emedicine.medscape.com/article/135478-overview

Feb 15th, 2022 - Background The complement system is part of the innate immune system. The complement system plays an important part in defense against pyogenic organisms. It promotes the inflammatory response, eliminates pathogens, and enhances the immune respons...

Genetic workup as a complementary tool for the diagnosis of primary complement componen...
https://doi.org/10.1007/s00431-022-04397-9 10.1016/j.molimm.2014.06.030 10.1007/s10875-017-0465-8 10.1016/j.anai.2018.01.014 10.1002/art.40158 10.1016/j.aller.2018.02.004 10.1038/ng.806 10.1136/jmedgenet-2018-105349 10.1046/j.1365-2249.2000.01113.x 10.1016/j.gene.2013.03.027 10.1016/j.molimm.2006.11.022 10.1097/MD.0b013e318180a6b4 10.7196/SAMJ.5571 10.1007/s15010-013-0439-6 10.1016/j.cll.2019.07.006
European Journal of Pediatrics; Shamriz O, Simon AJ et. al.

Feb 5th, 2022 - Diagnosis of primary complement deficiencies requires a high index of suspicion. Thus, susceptible patients are often underdiagnosed and untreated. Here, we present a multicenter experience with two novel inborn errors of the classical complement ...

Clinical Outcome and Underlying Genetic Cause of Functional Terminal Complement Pathway...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8793329
Journal of Clinical Immunology; Shears A, Steele C et. al.

Jan 28th, 2022 - Terminal complement pathway deficiencies often present with severe and recurrent infections. There is a lack of good-quality data on these rare conditions. This study investigated the clinical outcome and genetic variation in a large UK multi-cent...

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News  8 results

Fast Five Quiz: Refresh Your Knowledge on Key Aspects of Sepsis
https://reference.medscape.com/viewarticle/897550_2

Jun 7th, 2018 - Risk factors for severe sepsis and septic shock include the following: Extremes of age (<10 years and >70 years) Primary diseases (eg, liver cirrhosis, alcoholism, diabetes, cardiopulmonary diseases, solid malignancy, and hematologic malignancy) I...

Fast Five Quiz: Do You Know Current Vaccination Recommendations?
https://reference.medscape.com/viewarticle/867564_5

Aug 22nd, 2016 - A single dose of meningococcal vaccine ACWY (ie, Menactra or Menveo) vaccine at age 11 through 12 years, with a booster dose at age 16 years, is recommended for routine vaccination. Meningococcal vaccination with conjugate ACWY vaccine is indicate...

New Meningococcal B Vaccines: Who Gets Them and When?
https://www.medscape.com/viewarticle/849640

Aug 20th, 2015 - Hello. I'm Dr Sandra Fryhofer. Welcome to Medicine Matters. The topic: the new Advisory Committee on Immunization Practices (ACIP) meningococcal B (MenB) vaccination recommendation. Here's why it matters. The good news is that meningococcal diseas...

ACIP OKs Meningitis Vaccine (Menveo) for High-Risk Infants
https://www.medscape.com/viewarticle/813066

Oct 23rd, 2013 - The Centers for Disease Control and Prevention's Advisory Committee on Immunization Practices (ACIP) voted today to recommend (13 yes, 1 no, 1 abstain) the meningococcal conjugate vaccine MenACWY-CRM (Menveo, Novartis Vaccines) for use in infants ...

ACIP OKs Meningitis Vaccine (Menveo) for High-Risk Infants
https://www.staging.medscape.com/viewarticle/813066

Oct 23rd, 2013 - The Centers for Disease Control and Prevention's Advisory Committee on Immunization Practices (ACIP) voted today to recommend (13 yes, 1 no, 1 abstain) the meningococcal conjugate vaccine MenACWY-CRM (Menveo, Novartis Vaccines) for use in infants ...

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