ALLMedicine™ Addison Disease Center

Apr 10th, 2021 - Adrenal crisis is a life-threatening manifestation of acute adrenal insufficiency. One of the most important underlying causes is Addison disease (primary adrenal insufficiency).A 42-year-old White woman with a medical history of Addison disease o...

Dec 8th, 2020 - Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) (polyglandular endocrinopathy type 1) is a rare autosomal recessive disorder caused by mutations in the autoimmune regulator gene (AIRE). The major clinical features of APECED...

Nov 26th, 2020 - Oral once-daily dual-release hydrocortisone (DR-HC) replacement therapy has demonstrated an improved metabolic profile compared to conventional 3-times-daily (TID-HC) therapy among patients with primary adrenal insufficiency. This effect might be ...

Oct 18th, 2020 - BACKGROUND Autoimmune polyglandular syndrome type 1 (APS-1) is an extremely rare autoimmune disorder with an autosomal recessive inheritance pattern. Its manifestations present in chronological sequence of the components mucocutaneous candidiasis,...

Jun 28th, 2020 - Hashimoto's thyroiditis is known to cluster with other systemic autoimmune disorders. Rheumatic manifestations, such as a seronegative non-erosive polyarthritis have been described. The aim of this study was to evaluate the characteristics and the...

Dec 11th, 2019 - The adrenal glands are a pair of triangular glands, each about 2 inches long and 1 inch wide, that sit on top of the kidneys. They are responsible for the release of hormones that regulate metabolism, immune system function, and the salt-water bal...

Nov 27th, 2019 - Last year, during the post-Thanksgiving Day sales, an Instant Pot I'd had my eye on became available at a bargain price. So I got one, took it home, and read the instruction manual so as to not violate the Gay-Lussac law of the mass, pressure, and...

Aug 12th, 2019 - Not long ago, someone asked me for guidance on one of those infrequent but memorable office dilemmas: She inherited a patient who had been treated outside the medical mainstream, with untoward consequences. This patient sought treatment for some m...

Sep 29th, 2017 - Benign hyperpigmentation of the lips and fingers has been reported. 1 The average age of onset of LHS is 52 years, and it typically is diagnosed in white adults.

Jun 1st, 2017 - A 54-year-old female smoker was admitted to the hospital for fever and respiratory infection. On the day of admission, she reported lesions of the oral mucosa for the past several months.