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About 100 results

ALLMedicine™ Autoimmune Inner Ear Disease Center

Research & Reviews  35 results

Allergy, Immunotherapy, and Alternative Treatments for Dizziness.
https://doi.org/10.1016/j.otc.2021.05.020
Otolaryngologic Clinics of North America; Derebery MJ, Christopher L

Jul 24th, 2021 - Allergic reactions may result in central symptoms of dizziness, including nonspecific chronic imbalance, Meniere's disease, and autoimmune inner ear disease. Excepting first-generation antihistamines, and short-term use of steroids, most pharmacot...

Biologics for Immune-Mediated Sensorineural Hearing Loss.
https://doi.org/10.1016/j.otc.2021.05.005
Otolaryngologic Clinics of North America; Vambutas A, Davia DV

Jun 14th, 2021 - Immune-mediated hearing losses include autoimmune inner ear disease, sudden sensorineural hearing loss, and Meniere's disease. Standard therapy for an acute decline in hearing is timely use of corticosteroids. Although 60% to 70% of patients are i...

The Correlation of Clinical Corticosteroid Responsiveness With Expression of IL-6 in Pe...
https://doi.org/10.1097/MAO.0000000000003196
Otology & Neurotology : Official Publication of the Ameri... Gorthey SW, Pathak S et. al.

May 25th, 2021 - Autoimmune inner ear disease (AIED) patients will differentially express interleukin (IL)-6 based on corticosteroid responsiveness. AIED is characterized by periods of acute sensorineural hearing loss (SNHL). In a majority of patients corticostero...

The Pathogenesis of secondary forms of Autoimmune Inner Ear Disease (AIED): advancing b...
https://doi.org/10.1080/1744666X.2021.1879640
Expert Review of Clinical Immunology; Corazzi V, Hatzopoulos S et. al.

Jan 22nd, 2021 - Autoimmune Inner Ear Disease (AIED) can be of a primary or secondary type. To date, a clear pathogenesis of the disease is still not available. Focusing on the secondary forms of AIED, the aim of this review is to (i) assess and describe the heari...

Autoimmune Inner Ear Disease among Patients with Selective IgA Deficiency.
https://doi.org/10.1159/000509577
Audiology & Neuro-otology; Magen E, Blum I et. al.

Dec 15th, 2020 - Autoimmune inner ear disease (AIED) is a distinct clinical entity from sudden sensorineural hearing loss. The purpose of this study was to investigate the clinical characteristics of AIED in patients with selective IgA deficiency (sIgAD). This ret...

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Clinicaltrials.gov  5 results

A Clinical Trial of Anakinra for Steroid-Resistant Autoimmune Inner Ear Disease
https://clinicaltrials.gov/ct2/show/NCT01267994

Jan 10th, 2018 - Patients with immune mediated hearing loss (also known as autoimmune hearing loss) are typically treated with corticosteroids. Of those treated, approximately 60% respond, however, that response may be lost over time. Other therapies use to date h...

Study of the Effects of Anakinra in Corticosteroid-resistant Subjects With Sudden Sensorineural Hearing Loss
https://clinicaltrials.gov/ct2/show/NCT02414152

Mar 13th, 2017 - For patients that experience an acute, sensorineural decline in hearing, timely corticosteroid administration may result in preservation of some or all of the hearing. For patients with sudden sensorineural hearing loss who have failed to respond ...

The Effects of Gevokizumab in Corticosteroid-resistant Subjects With Autoimmune Inner Ear Disease
https://clinicaltrials.gov/ct2/show/NCT01950312

Feb 3rd, 2016 - The purpose of this study is to determine if gevokizumab therapy may be an alternate therapy in patients with steroid resistant Autoimmune Inner Ear Disease.

Intratympanic Steroid Treatment For The Prevention Of Inner Ear Toxicity Associated With Systemic Treatment With Cisplatin.
https://clinicaltrials.gov/ct2/show/NCT01285674

Jan 28th, 2011 - Cisplatin is a potent and widely used antineoplastic drug. Ototoxicity is a serious and dose-limiting side effect. The ototoxic effect of cisplatin is characterized by irreversible, progressive, bilateral, high-frequency, sensorineural hearing los...

Autoimmunity in Inner Ear Disease
https://clinicaltrials.gov/ct2/show/NCT00000361

Apr 24th, 2006 - The purpose of this study is to determine whether prednisone, methotrexate, and cyclophosphamide are effective in the treatment of rapidly progressive sensorineural hearing loss in both ears. This condition is called autoimmune inner ear disease (...

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