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About 6,660 results

ALLMedicine™ Eosinophilia Center

Research & Reviews  2,319 results

FIP1L1-PDGFRA-Associated Hypereosinophilic Syndrome as a Treatable Cause of Watershed I...
https://doi.org/10.1161/STROKEAHA.121.034191
Stroke Tennenbaum J, Groh M et. al.

Jul 26th, 2021 - Ischemic stroke has been reported in various conditions associated with eosinophilia. FIP1L1-PDGFRA fusion ([Fip1-like 1-platelet-derived growth factor receptor alpha]; F/P) leads to the proliferation of the eosinophilic lineage and thus to a clon...

Kimura Disease: A Rare and Difficult to Diagnose Entity.
https://doi.org/10.1007/s12105-021-01359-9 10.1093/cid/ciw135 10.1016/S0046-8177(79)80114-8 10.1111/j.1365-4632.2004.02361.x 10.1053/hupa.2002.128247 10.1007/s00405-003-0677-9 10.4061/2010/673908 10.1016/j.anl.2013.12.006 10.1159/000439346 10.1053/hupa.2002.124037 10.1016/B978-1-4160-2589-4.00013-9 10.1097/00000478-200404000-00010 10.1111/j.1440-0960.2011.00744.x
Head and Neck Pathology; Bishop C, Wilhelm A et. al.

Jul 20th, 2021 - Kimura disease (KD) is a rare inflammatory disorder which involves the head and neck. Due to its rarity and various findings, definitive diagnosis can be difficult to ascertain. Kimura disease is distinguished from other conditions, including angi...

Cytological Diagnosis Of Microfilaria In Clinically Unsuspected Cases: A Retrospective ...
https://doi.org/10.1111/cyt.13035
Cytopathology : Official Journal of the British Society F... Gupta D, Gupta P et. al.

Jul 17th, 2021 - Filariasis is a major health problem in India. Despite the high prevalence, microfilariae are rarely found in cytology smears. Most of the cases are incidentally found, solely or in association with other pathologies. The study was undertaken to a...

Current Perspectives on Severe Drug Eruption.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8286049
Clinical Reviews in Allergy & Immunology; Zhang J, Lei Z et. al.

Jul 17th, 2021 - Adverse drug reactions involving the skin are commonly known as drug eruptions. Severe drug eruption may cause severe cutaneous adverse drug reactions (SCARs), which are considered to be fatal and life-threatening, including Stevens-Johnson syndro...

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Guidelines  6 results

Chest CT Diagnosis and Clinical Management of Drug-Related Pneumonitis in Patients Rece...
https://doi.org/10.1016/j.chest.2020.11.027
Chest Johkoh T, Lee KS et. al.

Jan 15th, 2021 - Use of molecular targeting agents and immune checkpoint inhibitors (ICIs) has increased the frequency and broadened the spectrum of lung toxicity, particularly in patients with cancer. The diagnosis of drug-related pneumonitis (DRP) is usually ach...

Outpatient management and follow-up recommendations for adverse drug reactions: guideli...
https://www.ncbi.nlm.nih.gov/pubmed/31233575
Cutis Khanna R, Vaudreuil A et. al.

Jun 24th, 2019 - Acute generalized exanthematous pustulosis (AGEP), drug rash with eosinophilia and systemic symptoms (DRESS) syndrome, and Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) are types of adverse drug reactions (ADRs), each with their ...

Updated International Consensus Diagnostic Criteria for Eosinophilic Esophagitis: Proce...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174113
Gastroenterology Dellon ES, Liacouras CA et. al.

Jul 16th, 2018 - Over the last decade, clinical experiences and research studies raised concerns regarding use of proton pump inhibitors (PPIs) as part of the diagnostic strategy for eosinophilic esophagitis (EoE). We aimed to clarify the use of PPIs in the evalua...

Asthma management: A new phenotype-based approach using presence of eosinophilia and al...
https://doi.org/10.1111/all.13165
Allergy Terl M, Sedlák V et. al.

Mar 22nd, 2017 - Asthma is a heterogeneous disease. The Czech Pneumology and Allergology Societies commissioned 10 experts to review the literature and create joint national guidelines for managing asthma, reflecting this heterogeneity. The aim was to develop an e...

Guideline for the investigation and management of eosinophilia.
https://doi.org/10.1111/bjh.14488
British Journal of Haematology; Butt NM, Lambert J et. al.

Jan 23rd, 2017 - Guideline for the investigation and management of eosinophilia.|2017|Butt NM,Lambert J,Ali S,Beer PA,Cross NC,|diagnosis,epidemiology,etiology,therapy,

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Drugs  151 results see all →

Clinicaltrials.gov  46 results

A Longitudinal Study of Familial Hypereosinophilia (FE): Natural History and Markers of Disease Progression
https://clinicaltrials.gov/ct2/show/NCT00091871

Apr 23rd, 2020 - Affected members of families with familial hypereosinophilia (FE) will be admitted on this protocol. A thorough clinical evaluation will be performed biyearly with emphasis on potential sequelae of eosinophil-mediated tissue damage. Blood cells, b...

Collection of Blood, Body Fluid and Tissue Specimens From Healthy Donors for Use in In Vitro Research
https://clinicaltrials.gov/ct2/show/NCT00090662

Apr 19th, 2020 - This protocol is designed to provide blood, urine, sputum, stool, cerebrospinal fluid, skin biopsy and bone marrow aspirate samples from paid, volunteer donors for use in in vitro studies of eosinophilia and parasitic diseases. Donors meeting stan...

Activation and Function of Eosinophils in Conditions With Blood or Tissue Eosinophilia
https://clinicaltrials.gov/ct2/show/NCT00001406

Apr 7th, 2020 - Subjects admitted on this protocol will have elevated eosinophil counts in the peripheral blood or tissues or will be relatives of subjects with eosinophilia. Eosinophilic subjects will undergo an extensive clinical evaluation focused on the ident...

Long-term Access Program (LAP) of Mepolizumab for Subjects Who Participated in Study MEA115921
https://clinicaltrials.gov/ct2/show/NCT03298061

Mar 11th, 2020 - Eosinophilic Granulomatosis with Polyangiitis (EGPA), also referred to as Churg-Strauss syndrome, is a rare hyper-eosinophilic syndrome. Eosinophilia is central to the pathophysiology of EGPA and interleukin-5 (IL-5) is a key cytokine regulating t...

An Exploratory Study of Genetic and Clinical Factors for Serious Skin Reactions Among Users of Eslicarbazepine Acetate
https://clinicaltrials.gov/ct2/show/NCT02520557

Nov 25th, 2019 - This study is a genetic case-control study conducted in the United States. In case-control studies, cases with a condition of interest (in this case, individuals with SCAR [severe cutaneous adverse reactions] after initiating ESL); and controls, i...

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News  139 results

Fast Five Quiz: Presentation and Diagnosis of Systemic Sclerosis
https://reference.medscape.com/viewarticle/914839

Feb 3rd, 2021 - Systemic sclerosis (SSc) is a rare, heterogenous autoimmune disease characterized by sclerodermatous skin changes, vasculopathy, and involvement of the lungs and other organs. The cause of SSc is largely unknown, but both genetic and environmental...

Expert Highlights Advances in DRESS
https://www.medscape.com/viewarticle/944939

Jan 28th, 2021 - Mounting evidence suggests it's a mistake to reject the diagnosis of drug reaction with eosinophilia and systemic symptoms, or DRESS, simply because the interval between initiating a drug and symptom onset is less than 15 days, Sarah Walsh, MD, sa...

Asthma-COPD Overlap: Patients Have High Disease Burden
https://www.medscape.com/viewarticle/944179

Jan 14th, 2021 - Patients with asthma–chronic obstructive pulmonary disease overlap (ACO) experienced a higher burden of disease than patients with either asthma or COPD alone, a recent study has found. Approximately 20% of chronic obstructive airway disease cases...

Encouraging Results for New Epilepsy Drug
https://www.medscape.com/viewarticle/942561

Dec 13th, 2020 - Cenobamate (Xcopri), a new epilepsy drug, is safe and effective up to 1 year, new research shows. Post hoc analyses from an open-label study showed that seizure frequency was significantly reduced and the seizure-freedom rate was significantly imp...

Fast Five Quiz: Eosinophilic Asthma
https://reference.medscape.com/viewarticle/922981_3

Jul 5th, 2020 - Figure 1. Sputum culture Although the sputum eosinophilia level is the gold standard for diagnosing EA, this approach is not common because sputum processing and cell counting are too technical for most clinical centers. Nonetheless, there is cons...

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Patient Education  3 results see all →