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About 1,953 results

ALLMedicine Hypogammaglobulinemia Center

Research & Reviews  943 results

Dysfunctional Immune System Reconstitution After Rituximab Exposure In Utero.
https://doi.org/10.1097/MPH.0000000000001871
Journal of Pediatric Hematology/oncology; Clark R, Lindsey D et. al.

Jun 26th, 2020 - Rituximab is an antibody that binds to B-lymphocytes and is increasingly used during pregnancy. As an immunoglobulin G, it will transfer across the placenta. Previous case reports describe a diversity of clinical presentations in neonates born fol...

Persistent hypogammaglobulinemia in pediatric solid organ transplant recipients.
https://doi.org/10.1111/ctr.14021
Clinical Transplantation; Pellett Madan R, Penkert RR et. al.

Jun 23rd, 2020 - Hypogammaglobulinemia has not been well studied in transplanted children. We quantified plasma immunoglobulin (Ig) and lymphocyte phenotypes among 31 pediatric heart and kidney recipients for two years post-transplant and from 10 non-transplanted ...

Complement activation by human IgG antibodies to galactose-alpha-1,3-galactose.
https://doi.org/10.1111/imm.13229
Immunology Bernth Jensen JM, Laursen NS et. al.

Jun 23rd, 2020 - Some human antibodies may paradoxically inhibit complement activation on bacteria and enhance pathogen survival in humans. This property was also claimed for IgG antibodies reacting with terminal Galα3Gal (IgG anti-αGal), a naturally occurring and...

Good syndrome with cytomegalovirus hepatitis: successful resection of Thymoma: a case r...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296951
Journal of Cardiothoracic Surgery; Isobe S, Sano A et. al.

Jun 16th, 2020 - Good syndrome is a rare condition, manifesting as immunodeficiency due to hypogammaglobulinemia associated with thymoma. Herein, we present a patient with Good syndrome whose thymoma was resected after treatment of cytomegalovirus hepatitis. The p...

Clinical, Immunologic, and Molecular Spectrum of Patients with Immunodeficiency, Centro...
https://doi.org/10.2174/1871530320666200613204426
Endocrine, Metabolic & Immune Disorders Drug Targets; Kiaee F, Zaki-Dizaji M et. al.

Jun 13th, 2020 - Immunodeficiency, centromeric instability and facial dysmorphism )ICF) syndrome is a rare autosomal recessive immune disorder presenting with hypogammaglobulinemia, developmental delay, and facial anomalies. The ICF type 1, type 2, type 3 and type...

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Drugs  4 results see all →

Clinicaltrials.gov  973 results

Dysfunctional Immune System Reconstitution After Rituximab Exposure In Utero.
https://doi.org/10.1097/MPH.0000000000001871
Journal of Pediatric Hematology/oncology; Clark R, Lindsey D et. al.

Jun 26th, 2020 - Rituximab is an antibody that binds to B-lymphocytes and is increasingly used during pregnancy. As an immunoglobulin G, it will transfer across the placenta. Previous case reports describe a diversity of clinical presentations in neonates born fol...

Persistent hypogammaglobulinemia in pediatric solid organ transplant recipients.
https://doi.org/10.1111/ctr.14021
Clinical Transplantation; Pellett Madan R, Penkert RR et. al.

Jun 23rd, 2020 - Hypogammaglobulinemia has not been well studied in transplanted children. We quantified plasma immunoglobulin (Ig) and lymphocyte phenotypes among 31 pediatric heart and kidney recipients for two years post-transplant and from 10 non-transplanted ...

Complement activation by human IgG antibodies to galactose-alpha-1,3-galactose.
https://doi.org/10.1111/imm.13229
Immunology Bernth Jensen JM, Laursen NS et. al.

Jun 23rd, 2020 - Some human antibodies may paradoxically inhibit complement activation on bacteria and enhance pathogen survival in humans. This property was also claimed for IgG antibodies reacting with terminal Galα3Gal (IgG anti-αGal), a naturally occurring and...

Good syndrome with cytomegalovirus hepatitis: successful resection of Thymoma: a case r...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296951
Journal of Cardiothoracic Surgery; Isobe S, Sano A et. al.

Jun 16th, 2020 - Good syndrome is a rare condition, manifesting as immunodeficiency due to hypogammaglobulinemia associated with thymoma. Herein, we present a patient with Good syndrome whose thymoma was resected after treatment of cytomegalovirus hepatitis. The p...

Clinical, Immunologic, and Molecular Spectrum of Patients with Immunodeficiency, Centro...
https://doi.org/10.2174/1871530320666200613204426
Endocrine, Metabolic & Immune Disorders Drug Targets; Kiaee F, Zaki-Dizaji M et. al.

Jun 13th, 2020 - Immunodeficiency, centromeric instability and facial dysmorphism )ICF) syndrome is a rare autosomal recessive immune disorder presenting with hypogammaglobulinemia, developmental delay, and facial anomalies. The ICF type 1, type 2, type 3 and type...

see more →

News  33 results

Cautionary Findings on Acquired Immunodeficiency From Anti-CD20 MS Therapy
https://www.medscape.com/viewarticle/929997

May 4th, 2020 - REPORTING FROM AAN 2020 Thirty-eight percent of a large cohort of multiple sclerosis (MS) patients developed low IgM and 7.4% became hypogammaglobulinemic during a mean 30 months of follow-up on anti-CD20 therapy, Brandi L. Vollmer, MPH, reported ...

Hypogammaglobulinemia and infection risk clarified in MS patients on anti-CD20 agents
https://www.mdedge.com/multiplesclerosishub/article/209320/multiple-sclerosis/hypogammaglobulinemia-and-infection-risk/page/0/1

Oct 2nd, 2019 - Ocrelizumab Tobias Derfuss, MD, provided data on infection rates in the pivotal phase 3 OPERA and ORATIO double-blind clinical trials combined with their long-term, open-label extensions totaling 288 weeks, or nearly 6 years, of follow-up. Serum I.

Plerixafor produced dramatic responses in severe WHIM syndrome
https://www.mdedge.com/familymedicine/article/192393/anemia/plerixafor-produced-dramatic-responses-severe-whim-syndrome
MDedge Hematology and Oncology; Amy Karon

Jan 9th, 2019 - Low-dose treatment with plerixafor, a CXC chemokine receptor 4 antagonist, was well tolerated and markedly improved severe presentations of warts, hypogammaglobulinemia, infections, and myelokathexis (WHIM) syndrome in three patients who could not.

Long-term side effects of CAR T cells mostly mild
https://www.mdedge.com/hematology-oncology/article/192072/cellular-therapy/long-term-side-effects-car-t-cells-mostly-mild
Neil Osterweil

Jan 4th, 2019 - SAN DIEGO – Longer-term follow-up of patients treated with CD19-targeted chimeric antigen receptor (CAR) T cells for hematologic malignancies indicates that the altered cells are generally safe, with most late events being mild in nature and possi.

Hypogammaglobulinemia Screening Needed for Patients Receiving Rituximab
https://www.medscape.com/viewarticle/904454

Nov 7th, 2018 - NEW YORK (Reuters Health) - Patients being considered for rituximab therapy should be screened for hypogammaglobulinemia before and after rituximab administration, researchers report. Several reports have described prolonged hypogammaglobulinemia ...

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