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About 4,506 results

ALLMedicine™ Immunodeficiencies Center

Research & Reviews  2,183 results

Update on Real-World Use of Subcutaneous Immunoglobulins in Patients with Immunodeficie...
https://doi.org/10.1080/1744666X.2021.1913122
Expert Review of Clinical Immunology; Borte M, Anderson-Smits C et. al.

Apr 28th, 2021 - SummaryImmunoglobulin replacement therapy has been shown in clinical trials to be an important therapeutic option for reducing the incidence of serious bacterial infections and improving the quality of life in patients with primary and secondary i...

Pneumococcal serotype-specific cut-offs based on antibody responses to pneumococcal pol...
https://doi.org/10.1016/j.vaccine.2021.04.015
Vaccine Park MA, Jenkins SM et. al.

Apr 26th, 2021 - Antibody responses to pneumococcal polysaccharide vaccination are frequently used as a diagnostic tool for humoral immunodeficiencies, part of the larger collection of inborn errors of immunity. Currently, arbitrary criteria, such as a serotype sp...

Initial presenting manifestations in 16,486 patients with Inborn Errors of Immunity inc...
https://doi.org/10.1016/j.jaci.2021.04.015
The Journal of Allergy and Clinical Immunology; Thalhammer J, Kindle G et. al.

Apr 25th, 2021 - Inborn errors of immunity (IEI) are rare diseases, which makes diagnosis a challenge. A better description of the initial presenting manifestations should improve awareness and avoid diagnostic delay. Whilst increased infection susceptibility is a...

Benefits of immunoglobulin substitution in primary and secondary immunodeficiencies: In...
https://doi.org/10.5414/CP203952
International Journal of Clinical Pharmacology and Therap... Bauhofer A, Schimo S et. al.

Apr 16th, 2021 - To assess the safety, tolerability, and effectiveness of the intravenous immunoglobulin (IVIG) Intratect 100 g/L in a prospective, large-scale non-interventional study (NIS) of patients with a wide range of antibody deficiencies as well as other i...

Clinical heterogeneity among pediatric patients with autoimmune type 1 diabetes stratif...
https://doi.org/10.1111/pedi.13208
Pediatric Diabetes; Anna H, Małgorzata S et. al.

Apr 11th, 2021 - Type 1 diabetes (T1D) may coexist with primary immunodeficiencies, indicating a shared genetic background. To evaluate the prevalence and clinical characteristics of immunoglobulin deficiency (IgD) among children with T1D. Serum samples and medica...

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Guidelines  1 results

Grifols announces FDA approval of Xembify®, 20% subcutaneous immunoglobulin for primary immunodeficiencies
https://www.grifols.com/en/view-news/-/news/grifols-announces-fda-approval-of-xembify-20-subcutaneous-immunoglobulin-for-primary-immunodeficiencies

Jul 4th, 2019 - Grifols (MCE:GRF, MCE:GRF.P NASDAQ:GRFS), a leading global producer of plasma-derived medicines, announced today that Xembify®, its new 20% subcutaneous immunoglobulin, has been approved by the U.S. Food and Drug Administration (FDA). Xembify® is ...

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Drugs  19 results see all →

Clinicaltrials.gov  2,247 results

Update on Real-World Use of Subcutaneous Immunoglobulins in Patients with Immunodeficie...
https://doi.org/10.1080/1744666X.2021.1913122
Expert Review of Clinical Immunology; Borte M, Anderson-Smits C et. al.

Apr 28th, 2021 - SummaryImmunoglobulin replacement therapy has been shown in clinical trials to be an important therapeutic option for reducing the incidence of serious bacterial infections and improving the quality of life in patients with primary and secondary i...

Pneumococcal serotype-specific cut-offs based on antibody responses to pneumococcal pol...
https://doi.org/10.1016/j.vaccine.2021.04.015
Vaccine Park MA, Jenkins SM et. al.

Apr 26th, 2021 - Antibody responses to pneumococcal polysaccharide vaccination are frequently used as a diagnostic tool for humoral immunodeficiencies, part of the larger collection of inborn errors of immunity. Currently, arbitrary criteria, such as a serotype sp...

Initial presenting manifestations in 16,486 patients with Inborn Errors of Immunity inc...
https://doi.org/10.1016/j.jaci.2021.04.015
The Journal of Allergy and Clinical Immunology; Thalhammer J, Kindle G et. al.

Apr 25th, 2021 - Inborn errors of immunity (IEI) are rare diseases, which makes diagnosis a challenge. A better description of the initial presenting manifestations should improve awareness and avoid diagnostic delay. Whilst increased infection susceptibility is a...

Benefits of immunoglobulin substitution in primary and secondary immunodeficiencies: In...
https://doi.org/10.5414/CP203952
International Journal of Clinical Pharmacology and Therap... Bauhofer A, Schimo S et. al.

Apr 16th, 2021 - To assess the safety, tolerability, and effectiveness of the intravenous immunoglobulin (IVIG) Intratect 100 g/L in a prospective, large-scale non-interventional study (NIS) of patients with a wide range of antibody deficiencies as well as other i...

Clinical heterogeneity among pediatric patients with autoimmune type 1 diabetes stratif...
https://doi.org/10.1111/pedi.13208
Pediatric Diabetes; Anna H, Małgorzata S et. al.

Apr 11th, 2021 - Type 1 diabetes (T1D) may coexist with primary immunodeficiencies, indicating a shared genetic background. To evaluate the prevalence and clinical characteristics of immunoglobulin deficiency (IgD) among children with T1D. Serum samples and medica...

see more →

News  53 results

Novel Study Explores Link Between Primary Immunodeficiencies, Rheumatic Diseases
https://www.staging.medscape.com/viewarticle/939605

Oct 21st, 2020 - Fully 48% of patients with autoimmune rheumatic diseases who developed persistent hypogammaglobulinemia after initiating treatment with immunomodulatory agents harbored gene variants associated with inborn errors of immunity, according to the find...

Novel Study Explores Link Between Primary Immunodeficiencies, Rheumatic Diseases
https://www.medscape.com/viewarticle/939605

Oct 21st, 2020 - Fully 48% of patients with autoimmune rheumatic diseases who developed persistent hypogammaglobulinemia after initiating treatment with immunomodulatory agents harbored gene variants associated with inborn errors of immunity, according to the find...

COVID-19 Outcomes Vary Widely in Patients With Primary Immunodeficiencies
https://www.staging.medscape.com/viewarticle/939374

Oct 19th, 2020 - NEW YORK (Reuters Health) - Clinical outcomes of COVID-19 in patients with primary immunodeficiency diseases range from mild illness to death, according to a small case series. "We were first surprised that we had only a few cases considering how ...

COVID-19 Outcomes Vary Widely in Patients With Primary Immunodeficiencies
https://www.medscape.com/viewarticle/939374

Oct 19th, 2020 - NEW YORK (Reuters Health) - Clinical outcomes of COVID-19 in patients with primary immunodeficiency diseases range from mild illness to death, according to a small case series. "We were first surprised that we had only a few cases considering how ...

Spotting immunodeficiency in the pediatric dermatology clinic
https://www.mdedge.com/dermatology/article/210332/rare-diseases/spotting-immunodeficiency-pediatric-dermatology-clinic?channel=39212
Jim Kling

Oct 17th, 2019 - SEATTLE – Immunodeficiency in children can look much like eczematous dermatitis. Be aware of this potential diagnosis.

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Patient Education  3 results see all →