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About 17,723 results

ALLMedicine™ Neutropenia Center

Research & Reviews  5,990 results

Immunological features and complications in patients with glycogen storage disease 1b a...
https://doi.org/10.1111/petr.14104
Pediatric Transplantation; Shimizu S, Sakamoto S et. al.

Aug 3rd, 2021 - LT is an elective treatment choice for children diagnosed with GSD1b that can improve their quality of life and stabilize their glucose intolerance. However, careful attention should be paid to immunosuppression after LT due to the susceptibility ...

Favorable outcomes after heart transplantation in Barth syndrome.
https://doi.org/10.1016/j.healun.2021.06.017
The Journal of Heart and Lung Transplantation : the Offic... Li Y, Godown J et. al.

Aug 1st, 2021 - Barth Syndrome (BTHS) is a rare, X-linked disease characterized by cardioskeletal myopathy and neutropenia. Comparative outcomes after heart transplantation have not been reported. We identified BTHS recipients across 3 registries (Pediatric Heart...

Fatal recurrent disseminated Lomentospora prolificans infection during autologous hemat...
https://doi.org/10.1111/tid.13701
Transplant Infectious Disease : an Official Journal of Th... Gow-Lee V, Moyers JT et. al.

Jul 31st, 2021 - Infections with Scedosporium and Lomentospora species, in particular Lomentospora (previously Scedosporium) prolificans, are nearly universally fatal and rapidly-progressive in the transplant population. We report a case of a patient with diffuse ...

The role of procalcitonin and presepsin in the septic febrile neutropenia in acute leuk...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321513
PloS One; Moustafa R, Albouni T et. al.

Jul 30th, 2021 - The source of bacterial infection in neutropenic acute leukemia patients is detected in about 20-30% of cases. Bacterial cultures may require a long incubation period and risk false-positive and false- negative results. Therefore, biomarkers disti...

Cetuximab-induced rash is associated with overall survival in patients with recurrent/m...
https://doi.org/10.1007/s00280-021-04328-9 10.1007/s12325-018-0791-0 10.1056/NEJMoa0802656 10.1016/S0140-6736(19)32591-7 10.3816/CCC.2008.n.007 10.1155/2014/734249 10.1002/ijc.27654 10.1007/s11523-013-0257-x 10.1016/S1470-2045(09)70311-0 10.1016/j.ijrobp.2016.03.011 10.3389/fonc.2018.00616 10.2165/11598190-000000000-00000 10.1016/j.imlet.2004.08.012
Cancer Chemotherapy and Pharmacology; Göksu SS, Tatlı AM et. al.

Jul 28th, 2021 - In this study, we looked for whether treatment-induced rash predicts treatment efficacy in patients with recurrent/metastatic HNSCC treated with Cetuximab and chemotherapy. Patients who were treated with platinum-based chemotherapy and cetuximab f...

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Guidelines  14 results

Emerging challenges in the evaluation of fever in cancer patients at risk of febrile ne...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682766
Supportive Care in Cancer : Official Journal of the Multi... Cooksley T, Font C et. al.

Nov 25th, 2020 - Patients with cancer are at higher risk of more severe COVID-19 infection and have more associated complications. The position paper describes the management of cancer patients, especially those receiving anticancer treatment, during the COVID-19 ...

Management and Appropriate Use of Diazoxide in Infants and Children with Hyperinsulinism.
https://doi.org/10.1210/clinem/dgaa543
The Journal of Clinical Endocrinology and Metabolism; Brar PC, Heksch R et. al.

Aug 19th, 2020 - The diagnosis of hypoglycemia and the use of diazoxide have risen in the last decade. Diazoxide is the only Food and Drug Agency-approved pharmacologic treatment for neonatal hypoglycemia caused by hyperinsulinism (HI). Recent publications have hi...

ACR Appropriateness Criteria® Acute Nonlocalized Abdominal Pain.
https://doi.org/10.1016/j.jacr.2018.09.010
Journal of the American College of Radiology : JACR; , Scheirey CD et. al.

Nov 6th, 2018 - The range of pathology in adults that can produce abdominal pain is broad and necessitates an imaging approach to evaluate many different organ systems. Although localizing pain prompts directed imaging/management, clinical presentations may vary ...

Antimicrobial Prophylaxis for Adult Patients With Cancer-Related Immunosuppression: ASC...
https://doi.org/10.1200/JCO.18.00374
Journal of Clinical Oncology : Official Journal of the Am... Taplitz RA, Kennedy EB et. al.

Sep 5th, 2018 - To provide an updated joint ASCO/Infectious Diseases Society of America (IDSA) guideline on antimicrobial prophylaxis for adult patients with immunosuppression associated with cancer and its treatment. ASCO and IDSA convened an update Expert Panel...

Outpatient Management of Fever and Neutropenia in Adults Treated for Malignancy: Americ...
https://doi.org/10.1200/JCO.2017.77.6211
Journal of Clinical Oncology : Official Journal of the Am... Taplitz RA, Kennedy EB et. al.

Feb 21st, 2018 - Purpose To provide an updated joint ASCO/Infectious Diseases Society of American (IDSA) guideline on outpatient management of fever and neutropenia in patients with cancer. Methods ASCO and IDSA convened an Update Expert Panel and conducted a syst...

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Drugs  268 results see all →

Clinicaltrials.gov  286 results

Natural History Study for BEN
https://clinicaltrials.gov/ct2/show/NCT00059423

Apr 24th, 2020 - Benign ethnic neutropenia (BEN) is defined by peripheral blood absolute neutrophil count less than 1.5 x 10 (9) per liter without an increase in infections. This condition has been described in individuals of African descent. Although these indivi...

Intensity-Modulated Radiation Therapy and Paclitaxel With or Without Pazopanib Hydrochloride in Treating Patients With Anaplastic Thyroid Cancer
https://clinicaltrials.gov/ct2/show/NCT01236547

Apr 17th, 2020 - PRIMARY OBJECTIVES: I. To evaluate the safety of IMRT, paclitaxel, and pazopanib (pazopanib hydrochloride) suspension. (Run-in component) II. To evaluate and compare overall survival at 1 year from study registration. (Phase II component) SECONDAR...

G-CSF in Preventing Neutropenia During First-Line Treatment With Chemotherapy and Bevacizumab in Patients With Metastatic Colorectal Cancer
https://clinicaltrials.gov/ct2/show/NCT00541125

Mar 30th, 2020 - OBJECTIVES: Primary Determine if primary prophylaxis comprising filgrastim (G-CSF) makes it possible to obtain neutropenia lower than grade 4 or a 30% decrease in fever in patients with metastatic colorectal cancer receiving first-line FOLFIRI and...

Epirubicin Versus Docetaxel Plus Cyclophosphamide in Lymph Node Negative, ER-positive, Her2-negative Breast Cancer
https://clinicaltrials.gov/ct2/show/NCT02549677

Mar 10th, 2020 - This is a non-inferiority study. According to previous study results, the investigators hypothesize the incidence of grade 3-4 neutropenia is 40%, with a α of 0.05 and β of 0.8, a sample size of 264 cases if needed.

A Study Comparing Two Standard of Care Adjuvant Chemotherapy Regimens for Lower Risk HER-2 Positive Breast Cancer
https://clinicaltrials.gov/ct2/show/NCT03705429

Mar 2nd, 2020 - Multi-center, open-label, randomized trial of patients with low-risk, HER2+ disease, who will receive adjuvant taxane-based chemotherapy (i.e. docetaxel and cyclophosphamide with trastuzumab [TC-H] or weekly paclitaxel with trastuzumab [P-H]) at t...

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News  531 results

Lifileucel Promising Against Unresponsive Malignant Melanoma
https://www.medscape.com/viewarticle/952183

Jun 2nd, 2021 - NEW YORK (Reuters Health) - Lifileucel shows promise in metastatic-melanoma patients whose disease had progressed on standard immune-checkpoint inhibitors (ICI) and other therapies, according to a small open-label trial. "Lifileucel is a ground-br...

Lobaplatin 'Promising' in Nasopharyngeal Cancer
https://www.medscape.com/viewarticle/950478

May 4th, 2021 - Lobaplatin-based induction plus chemoradiation was as effective as, and safer than, a cisplatin-based regimen in a phase 3 trial of more than 500 patients with advanced nasopharyngeal carcinoma. The lobaplatin regimen proved to be a "promising alt...

Gemcitabine Maintenance After First-Line Chemo Prolongs PFS in Malignant Mesothelioma
https://www.medscape.com/viewarticle/945372

Feb 8th, 2021 - NEW YORK (Reuters Health) - Gemcitabine maintenance therapy after first-line chemotherapy significantly prolonged progression-free survival (PFS) in patients with malignant mesothelioma, according to results of the Dutch NVALT19 trial. "Almost all...

Convenience, Cost Sway Choice of G-CSF Added to Chemo
https://www.medscape.com/viewarticle/945109

Feb 2nd, 2021 - The choice of whether to use granulocyte colony-stimulating factor (G-CSF) for the prevention of febrile neutropenia for patients undergoing chemotherapy depends on whether it is being used for primary or secondary prophylaxis, indicates a survey ...

Jury's Still Out on Trifluridine/Tipiracil Plus Bev in mCRC
https://www.medscape.com/viewarticle/944927

Jan 29th, 2021 - First-line trifluridine/tipiracil plus bevacizumab (TT-B) offered a slight survival benefit over capecitabine plus bevacizumab (C-B) in patients with unresectable metastatic colorectal cancer in the final analysis of the TASCO1 trial. The median p...

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