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About 5,992 results

ALLMedicine Splenomegaly Center

Research & Reviews  2,895 results

Type I interferon-independent T cell impairment in a Tmem173 N153S/WT mouse model of ST...
https://doi.org/10.1016/j.clim.2020.108466
Clinical Immunology (Orlando, Fla.); Siedel H, Roers A et. al.

May 29th, 2020 - STING-associated vasculopathy with onset in infancy (SAVI) is an autoimmune disease caused by heterozygous gain of function mutations of STING (stimulator of interferon genes) that had initially been classified as a type I interferonopathy. We rec...

Neoplastic fibrocytes play an essential role in bone marrow fibrosis in Jak2V617F-induc...
https://doi.org/10.1038/s41375-020-0880-3
Leukemia Ozono Y, Shide K et. al.

May 28th, 2020 - Primary myelofibrosis (PMF) is a myeloproliferative neoplasm (MPN) characterized by clonal myeloproliferation, progressive bone marrow (BM) fibrosis, splenomegaly, and anemia. BM fibrosis was previously thought to be a reactive phenomenon induced ...

Varices on Computed Tomography Could Predict Survival after Hepatic Resection in Patien...
https://doi.org/10.1111/jgh.15117
Journal of Gastroenterology and Hepatology; Lee DH, Chung JW et. al.

May 26th, 2020 - To evaluate whether presence of varices on CT could predict treatment outcome for hepatocellular carcinoma (HCC) patients. We enrolled 241 patients with single HCC≤5cm treated by surgery. Using preoperative CT/endoscopy, patients were classified i...

Ultrasonographic (US) Two-Dimensional Measurement of Spleen Is Superior to Traditional ...
https://doi.org/10.1007/s10620-020-06332-0
Digestive Diseases and Sciences; Lui FH, Ma P et. al.

May 24th, 2020 - Splenomegaly measured by spleen length has been an imaging evidence for cirrhosis. However, data remains lacking on the value of other US findings for diagnosing cirrhosis. This study evaluated the value of spleen two-dimensional measurements (2D,...

FDG PET/CT in a Patient With Mantle Cell Lymphoma and COVID-19: Typical Findings.
https://doi.org/10.1097/RLU.0000000000003113
Clinical Nuclear Medicine; Playe M, Siavellis J et. al.

May 19th, 2020 - A 52-year-old woman with no medical history was admitted on March 18, 2020, presenting since 3 days asthenia, abdominal pain, and dry cough but no fever. Adenomegalies, splenomegaly, leukocytosis, and elevated LDH suggested mature lymphoproliferat...

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Guidelines  1 results

Revised diagnostic criteria and classification for the autoimmune lymphoproliferative s...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2953894
Blood Oliveira JB, Bleesing JJ et. al.

Jun 11th, 2010 - Lymphadenopathy in children for which no infectious or malignant cause can be ascertained constitutes a challenging diagnostic dilemma. Autoimmune lymphoproliferative syndrome (ALPS) is a human genetic disorder of lymphocyte apoptosis resulting in...

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Drugs  1 results see all →

Clinicaltrials.gov  2,987 results

Type I interferon-independent T cell impairment in a Tmem173 N153S/WT mouse model of ST...
https://doi.org/10.1016/j.clim.2020.108466
Clinical Immunology (Orlando, Fla.); Siedel H, Roers A et. al.

May 29th, 2020 - STING-associated vasculopathy with onset in infancy (SAVI) is an autoimmune disease caused by heterozygous gain of function mutations of STING (stimulator of interferon genes) that had initially been classified as a type I interferonopathy. We rec...

Neoplastic fibrocytes play an essential role in bone marrow fibrosis in Jak2V617F-induc...
https://doi.org/10.1038/s41375-020-0880-3
Leukemia Ozono Y, Shide K et. al.

May 28th, 2020 - Primary myelofibrosis (PMF) is a myeloproliferative neoplasm (MPN) characterized by clonal myeloproliferation, progressive bone marrow (BM) fibrosis, splenomegaly, and anemia. BM fibrosis was previously thought to be a reactive phenomenon induced ...

Varices on Computed Tomography Could Predict Survival after Hepatic Resection in Patien...
https://doi.org/10.1111/jgh.15117
Journal of Gastroenterology and Hepatology; Lee DH, Chung JW et. al.

May 26th, 2020 - To evaluate whether presence of varices on CT could predict treatment outcome for hepatocellular carcinoma (HCC) patients. We enrolled 241 patients with single HCC≤5cm treated by surgery. Using preoperative CT/endoscopy, patients were classified i...

Ultrasonographic (US) Two-Dimensional Measurement of Spleen Is Superior to Traditional ...
https://doi.org/10.1007/s10620-020-06332-0
Digestive Diseases and Sciences; Lui FH, Ma P et. al.

May 24th, 2020 - Splenomegaly measured by spleen length has been an imaging evidence for cirrhosis. However, data remains lacking on the value of other US findings for diagnosing cirrhosis. This study evaluated the value of spleen two-dimensional measurements (2D,...

FDG PET/CT in a Patient With Mantle Cell Lymphoma and COVID-19: Typical Findings.
https://doi.org/10.1097/RLU.0000000000003113
Clinical Nuclear Medicine; Playe M, Siavellis J et. al.

May 19th, 2020 - A 52-year-old woman with no medical history was admitted on March 18, 2020, presenting since 3 days asthenia, abdominal pain, and dry cough but no fever. Adenomegalies, splenomegaly, leukocytosis, and elevated LDH suggested mature lymphoproliferat...

see more →

News  105 results

Atraumatic splenic rupture in acute myeloid leukemia
https://www.mdedge.com/ccjm/article/211092/hematology/atraumatic-splenic-rupture-acute-myeloid-leukemia?channel=263
Karthik Gnanapandithan, MD, MS

Nov 1st, 2019 - A 50-year-old man with acute myeloid leukemia (AML) with a complex karyotype was admitted to the hospital with several days of dull, left-sided abdominal pain. His most recent bone marrow biopsy showed 30% blasts, and immunophenotyping was suggest.

Long-acting interferon recommended for PV
https://www.mdedge.com/hematology-oncology/article/192212/cythemias/long-acting-interferon-recommended-pv
HT Staff

Dec 20th, 2018 - Image courtesy of AFIP Polycythemia vera The European Medicines Agency’s Committee for Medicinal Products for Human Use (CHMP) has recommended approval for ropeginterferon alfa-2b (BESREMi®) to treat adults who have polycythemia vera (PV) without.

Asymptomatic Visceral Leishmaniasis Common in Operation Iraqi Freedom Soldiers
https://www.medscape.com/viewarticle/903337

Oct 14th, 2018 - NEW YORK (Reuters Health) - As many as one in five U.S. soldiers deployed in Operation Iraqi Freedom (OIF) have serological evidence of asymptomatic visceral Leishmania infantum infection (AVL), researchers report. "Clinicians should consider a li...

Adult-Onset Still Disease: Persistent Pruritic Papular Rash With Unique Histopathologic Findings
https://www.mdedge.com/dermatology/article/175877/rare-diseases/adult-onset-still-disease-persistent-pruritic-papular-rash/page/0/1

Sep 27th, 2018 - Comment Adult-onset Still disease is a systemic inflammatory condition that clinically manifests as spiking fevers, arthralgia, salmon-pink evanescent erythema, and lymphadenopathy. 2 The condition also can cause liver dysfunction, splenomegaly, pe.

A Case of Systemic Mastocytosis With Associated Clonal Hematological Non-Mast Cell Lineage Disease at VA Pittsburgh Healthcare System
https://www.mdedge.com/fedprac/avaho/article/174895/lymphoma-plasma-cell-disorders/case-systemic-mastocytosis-associated
Liman AD, Gandhi A et. al.

Sep 14th, 2018 - Introduction: Systemic mastocytosis (SM) is a rare myeloid neoplasm that is caused by accumulation of abnormal mast cells in the bone marrow, liver, spleen, and skin. The KIT D816V mutation encodes a constitutively activated receptor tyrosine kina.

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Patient Education  3 results see all →