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About 140 results

ALLMedicine™ Autoimmune Inner Ear Disease Center

Research & Reviews  47 results

Deep Phenotyping of Hearing Instability Disorders: Cohort Establishment, Biomarker Identification, Development of Novel Phenotyping Measures, and Discovery of Therapeutic Targets
https://clinicaltrials.gov/ct2/show/NCT04806282

Sep 21st, 2022 - Title: Deep Phenotyping of Hearing Instability Disorders: Cohort Establishment, Biomarker Identification, Development of Novel Phenotyping Measures and Discovery of Therapeutic Targets Study Description: Disorders of hearing instability remain poo...

Cochlear implantation in systemic autoimmune disease.
https://doi.org/10.1097/MOO.0000000000000839
Current Opinion in Otolaryngology & Head and Neck Surgery; Goh X, Muzaffar J et. al.

Aug 26th, 2022 - Autoimmune inner ear disease (AIED) is a rare, but likely underrecognized cause of hearing loss. However, hearing loss is common in systemic autoimmune disease and it is important for the clinician to be familiar with the spectrum of disease. In t...

The Impact of Intratympanic Steroid Dosage on Hearing Recovery in Sudden Sensorineural ...
https://doi.org/10.1177/00034894221120125
The Annals of Otology, Rhinology, and Laryngology; Nelson L, Swanson D et. al.

Aug 23rd, 2022 - To investigate how dexamethasone dosage impacts intratympanic steroid therapy (IST) for treatment of sudden sensorineural hearing loss (SSNHL). Retrospective review. Inclusion criteria identified subjects who received IST between January 1, 2010 a...

Use of biologics for treatment of autoimmune inner ear disease.
https://doi.org/10.1016/j.amjoto.2022.103576
American Journal of Otolaryngology; Balouch B, Meehan R et. al.

Aug 14th, 2022 - Biologic medications are novel therapeutics in the treatment of Autoimmune Inner Ear Disease (AIED), an etiology of Sensorineural Hearing Loss (SNHL). The goal of this study is to review the currently available literature on the efficacy of biolog...

Clinical characteristics of patients with dizziness/vertigo showing a dissociation betw...
https://doi.org/10.1177/01455613221113790
Ear, Nose, & Throat Journal; Li X, Ling X et. al.

Jul 12th, 2022 - To explore the clinical characteristics of patients with dizziness/vertigo who showed a dissociation between the results of the caloric test and video head impulse test (vHIT). A total of 327 patients who complained of dizziness/vertigo were conti...

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Clinicaltrials.gov  9 results

Deep Phenotyping of Hearing Instability Disorders: Cohort Establishment, Biomarker Identification, Development of Novel Phenotyping Measures, and Discovery of Therapeutic Targets
https://clinicaltrials.gov/ct2/show/NCT04806282

Sep 21st, 2022 - Title: Deep Phenotyping of Hearing Instability Disorders: Cohort Establishment, Biomarker Identification, Development of Novel Phenotyping Measures and Discovery of Therapeutic Targets Study Description: Disorders of hearing instability remain poo...

Effects of Anakinra in Subjects With Autoimmune Inner Ear Disease
https://clinicaltrials.gov/ct2/show/NCT03587701

Sep 9th, 2021 - This study will be evaluating whether or not anakinra (kineret) is superior to placebo for improving sustained hearing thresholds in patients with CR-MD and CR-AIED. Final enrollment is contingent on an acute decline in hearing in the active ear a...

Transtympanic Gentamicin vs. Steroids in Refractory Meniere's Disease
https://clinicaltrials.gov/ct2/show/NCT00802529

Jun 27th, 2019 - Meniere's disease is characterised by episodic spontaneous vertigo attacks with hearing loss, ringing sounds and fullness in the ear. In one out of five patients, standard first line medical treatment is not effective in controlling vertigo attack...

A Clinical Trial of Anakinra for Steroid-Resistant Autoimmune Inner Ear Disease
https://clinicaltrials.gov/ct2/show/NCT01267994

Jan 10th, 2018 - Patients with immune mediated hearing loss (also known as autoimmune hearing loss) are typically treated with corticosteroids. Of those treated, approximately 60% respond, however, that response may be lost over time. Other therapies use to date h...

Study of the Effects of Anakinra in Corticosteroid-resistant Subjects With Sudden Sensorineural Hearing Loss
https://clinicaltrials.gov/ct2/show/NCT02414152

Mar 13th, 2017 - For patients that experience an acute, sensorineural decline in hearing, timely corticosteroid administration may result in preservation of some or all of the hearing. For patients with sudden sensorineural hearing loss who have failed to respond ...

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