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About 9,440 results

ALLMedicine™ Eosinophilia Center

Research & Reviews  3,096 results

Tumor-associated tissue eosinophilia promotes angiogenesis and metastasis in head and n...
https://doi.org/10.1016/j.neo.2022.100855
Neoplasia (New York, N.Y.); Lee TL, Chen TH et. al.

Nov 22nd, 2022 - Eosinophils are terminally differentiated leukocytes that participate in the process of chronic inflammation and allergy and are able to release multiple cytokines into the surrounding tissue environment. Tumor-associated tissue eosinophilia (TATE...

Physiological microbial exposure transiently inhibits mouse lung ILC2 responses to alle...
https://doi.org/10.1038/s41590-022-01350-8
Nature Immunology; Block KE, Iijima K et. al.

Nov 22nd, 2022 - Lung group 2 innate lymphoid cells (ILC2s) control the nature of immune responses to airway allergens. Some microbial products, including those that stimulate interferons, block ILC2 activation, but whether this occurs after natural infections or ...

Do General Pathologists Assess Gastric and Duodenal Eosinophilia?
https://doi.org/10.5858/arpa.2022-0204-OA
Archives of Pathology & Laboratory Medicine; Saad AJ, Genta RM et. al.

Nov 19th, 2022 - Eosinophilic diseases of the gastrointestinal tract (EGIDs), eosinophilic gastritis (EoG), and eosinophilic duodenitis (EoD) are rarely suspected clinically and infrequently detected by pathologists. To determine whether histories of allergic or e...

Eosinophil depletion with benralizumab is associated with attenuated mannitol airway hy...
https://doi.org/10.1016/j.jaci.2022.10.028
The Journal of Allergy and Clinical Immunology; Chan R, Kuo CR et. al.

Nov 19th, 2022 - Airway hyperresponsiveness (AHR) and eosinophilia are hallmarks of persistent asthma. We investigated whether eosinophil depletion with benralizumab (Benra) might attenuate indirect mannitol AHR in severe uncontrolled asthma using a pragmatic open...

Subgroups in the treatment of nasal polyposis with dupilumab: A retrospective study.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9666224
Medicine Bertlich M, Freytag S et. al.

Nov 19th, 2022 - Dupilumab has been shown to be safe and effective in treating chronic rhinosinusitis with polyposis (CRSwNP). There is to this date no published data whether subgroups like patients with aspirin exacerbated respiratory disease (AERD), increased hi...

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Guidelines  8 results

Myeloid/Lymphoid Neoplasms with Eosinophilia and TK Fusion Genes, Version 3.2021, NCCN ...
https://doi.org/10.6004/jnccn.2020.0042
Journal of the National Comprehensive Cancer Network : JN... Gerds AT, Gotlib J et. al.

Sep 5th, 2020 - Eosinophilic disorders and related syndromes represent a heterogeneous group of neoplastic and nonneoplastic conditions, characterized by more eosinophils in the peripheral blood, and may involve eosinophil-induced organ damage. In the WHO classif...

Technical Review on the Management of Eosinophilic Esophagitis: A Report From the AGA I...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9473155
Gastroenterology Rank MA, Sharaf RN et. al.

May 4th, 2020 - Eosinophilic esophagitis (EoE) is a chronic inflammatory condition of the esophagus. Many new studies have been reported recently that describe EoE management. An expert panel was convened by the American Gastroenterological Association Institute ...

Outpatient management and follow-up recommendations for adverse drug reactions: guideli...
https://www.ncbi.nlm.nih.gov/pubmed/31233575
Cutis Khanna R, Vaudreuil A et. al.

Jun 25th, 2019 - Acute generalized exanthematous pustulosis (AGEP), drug rash with eosinophilia and systemic symptoms (DRESS) syndrome, and Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) are types of adverse drug reactions (ADRs), each with their ...

Updated International Consensus Diagnostic Criteria for Eosinophilic Esophagitis: Proce...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174113
Gastroenterology Dellon ES, Liacouras CA et. al.

Jul 17th, 2018 - Over the last decade, clinical experiences and research studies raised concerns regarding use of proton pump inhibitors (PPIs) as part of the diagnostic strategy for eosinophilic esophagitis (EoE). We aimed to clarify the use of PPIs in the evalua...

Clinical Pharmacogenetics Implementation Consortium Guideline for HLA Genotype and Use ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847474
Clinical Pharmacology and Therapeutics; Phillips EJ, Sukasem C et. al.

Feb 3rd, 2018 - The variant allele HLA-B*15:02 is strongly associated with greater risk of Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) in patients treated with carbamazepine or oxcarbazepine. The variant allele HLA-A*31:01 is associated wi...

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Drugs  250 results see all →

Clinicaltrials.gov  142 results

Pilot Study of Reduced-Intensity Hematopoietic Stem Cell Transplant of DOCK8 Deficiency
https://clinicaltrials.gov/ct2/show/NCT01176006

Oct 14th, 2022 - Background Mutations in the Dedicator of Cytokinesis-8 (DOCK8) gene are responsible for an immunodeficiency disease characterized by: severe cutaneous and sinopulmonary infections with bacterial organisms; extensive cutaneous viral infections with...

Mepolizumab in Episodic Angioedema With Eosinophilia
https://clinicaltrials.gov/ct2/show/NCT04128371

Oct 14th, 2022 - Episodic angioedema with eosinophilia (EAE), also known as Gleich s Syndrome,is a rare disorder characterized by recurrent episodes of urticaria, fever, angioedema, weight gain and dramatic eosinophilia that occur at 3- to 6-week intervals and res...

Eosinophil-driven Corticotherapy for Patients Hospitalized for COPD Exacerbation
https://clinicaltrials.gov/ct2/show/NCT04234360

Oct 14th, 2022 - The primary objective of this study is to compare treatment failure rates between a group of eosinophilic (eosinophilia > 2% on day 1 of hospitalization) patients hospitalised for a COPD exacerbation treated via corticotherapy versus a similar gro...

Ketotifen for Children With Functional Dyspepsia in Association With Duodenal Eosinophilia
https://clinicaltrials.gov/ct2/show/NCT02484248

Oct 12th, 2022 - This study is a double-blind, placebo-controlled, cross-over trial of ketotifen in children ages 8 through 17 inclusive that have a diagnosis of functional dyspepsia and have had continued abdominal pain despite acid reduction therapy in combinati...

Activation and Function of Eosinophils in Conditions With Blood or Tissue Eosinophilia
https://clinicaltrials.gov/ct2/show/NCT00001406

Oct 6th, 2022 - Study Description: This study is designed to collect data and clinical samples from participants with elevated eosinophil counts in the peripheral blood or tissues or their relatives to enhance our understanding of the mechanisms driving eosinophi...

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News  269 results

Long-Acting Muscarinic Antagonist Therapy Takes a Hit in GINA Update
https://www.medscape.com/viewarticle/981575

Sep 29th, 2022 - In keeping with the new trend for providing "living guidelines," the Global Initiative for Asthma (GINA) Scientific Committee released their latest update a few months ago. The push toward earlier initiation of inhaled corticosteroids (ICS) has do...

Updates in eosinophilic gastrointestinal diseases
https://www.mdedge.com/gihepnews/article/258193/upper-gi-tract/updates-eosinophilic-gastrointestinal-diseases
Kathryn A. Peterson, MD, MSCI

Sep 23rd, 2022 - Eosinophilic gastrointestinal diseases (EGIDs) are characterized by GI signs or symptoms occurring along with tissue eosinophilia. Eosinophilic esophagitis (EoE) is the more commonly recognized EGID as endoscopic and histopathologic diagnostic cri.

Pemigatinib Represents Transformative Treatment for Myeloid/Lymphoid Neoplasms With FGFR1 Rearrangement
https://www.onclive.com/view/pemigatinib-represents-transformative-treatment-for-myeloid-lymphoid-neoplasms-with-fgfr1-rearrangement

Sep 13th, 2022 - The efficacy displayed by pemigatinib (Pemazyre) in the treatment of patients with myeloid/lymphoid neoplasms (MLNs) with FGFR1 rearrangement has emphasized the need for chromosomal analysis to identify translocation of chromosome 8p11, according ...

Erythematous Papule on the Nasal Ala
https://www.mdedge.com/dermatology/article/257719/erythematous-papule-nasal-ala
Rohit Gupta, MD, Abdul Hafeez Diwan, MD, PhD et. al.

Sep 12th, 2022 - The Diagnosis: Cutaneous Lymphoid Hyperplasia Cutaneous lymphoid hyperplasia (CLH)(also known as pseudolymphoma or lymphocytoma cutis) is a benign inflammatory condition that typically presents as a flesh-colored to erythematous or violaceous papu.

Consensus Document Aids Schistosomiasis Management
https://www.medscape.com/viewarticle/980115

Sep 1st, 2022 - After malaria, human schistosomiasis is the parasitic disease with the highest morbidity and mortality worldwide. An estimated 236 million people are infected. Most are in sub-Saharan Africa. Complications lead to the deaths of 300,000 people each...

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Patient Education  11 results see all →