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About 675 results

ALLMedicine™ Hypereosinophilic Syndrome Center

Research & Reviews  245 results

Study in Pediatrics With HypEREosinophilic Syndrome (SPHERE)
https://clinicaltrials.gov/ct2/show/NCT04965636

Jan 10th, 2022 - The purpose of this study is to investigate the efficacy and safety of mepolizumab in children and adolescents with hypereosinophilic syndrome (HES) who are receiving standard of care (SoC) therapy.

Loeffler endocarditis with intracardiac thrombus: case report and literature review.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8713406
BMC Cardiovascular Disorders; Zhang Q, Si D et. al.

Dec 29th, 2021 - Loeffler endocarditis is a relatively rare and potentially life-threatening heart disease. This study aimed to identify the characteristic features of Loeffler endocarditis with intracardiac thrombus on a background of hypereosinophilic syndrome (...

A Rare Manifestation of IgG4-Related Disease and Concurrent Idiopathic Hypereosinophili...
https://doi.org/10.1093/ibd/izab307
Inflammatory Bowel Diseases; Dai C, Huang YH

Dec 7th, 2021 - A Rare Manifestation of IgG4-Related Disease and Concurrent Idiopathic Hypereosinophilic Syndrome as Extensive Gastrointestinal Lesions: A Case Report.|2021|Dai C,Huang YH,|

Myocarditis Pathology
https://emedicine.medscape.com/article/1612533-print

Nov 5th, 2021 - The term myocarditis refers to an inflammatory response within the myocardium that is not secondary to ischemic events or cardiac rejection in the setting of transplantation. The presence of myocyte necrosis is required for certain types of myocar...

Hypereosinophilia: a rare cause of stroke and multiorgan dysfunction.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8488726
BMJ Case Reports; Barbind KL, Boddu R et. al.

Oct 3rd, 2021 - Eosinophilia can occur due to a plethora of allergic, infective, neoplastic and idiopathic conditions. Hypereosinophilic syndrome (HES) is characterised by sustained eosinophilia and multiorgan dysfunction in the absence of an identifiable cause. ...

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Drugs  8 results see all →

Clinicaltrials.gov  9 results

Study in Pediatrics With HypEREosinophilic Syndrome (SPHERE)
https://clinicaltrials.gov/ct2/show/NCT04965636

Jan 10th, 2022 - The purpose of this study is to investigate the efficacy and safety of mepolizumab in children and adolescents with hypereosinophilic syndrome (HES) who are receiving standard of care (SoC) therapy.

Steroid Treatment for Hypereosinophilic Syndrome
https://clinicaltrials.gov/ct2/show/NCT01524536

Aug 6th, 2021 - This study aims to develop a model to determine whether a single, oral, weight-based dose of glucocorticoid (GC) can predict clinical and biologic response to GC s over the long term in subjects with hypereosinophilic syndrome (HES). Subjects with...

Phase II Gleevec Idiopathic Hypereosinophilic Syndrome
https://clinicaltrials.gov/ct2/show/NCT00230334

May 10th, 2021 - The purpose of the trial is to determine the safety and efficacy of Gleevec" in idiopathic hypereosinophilic syndrome (HES) and to characterize the molecular basis for the therapeutic benefit of Gleevec" in HES.

This Record Contains Information About the Mepolizumab Compassionate Use (CU) Product Activities: 104317: CU and Long-Term Access Study of Mepolizumab in HES. 201956:A Long-term Access Programme fo...
https://clinicaltrials.gov/ct2/show/NCT00244686

Nov 25th, 2020 - 104317: The market authorisation application for mepolizumab for the indication of hypereosinophilic syndrome (HES) was filed in 2008, but later the file was withdrawn due to outstanding questions from regulator's raised from the application. On t...

Prospective Registry of Eosinophilia With Respiratory Manifestations With Translational Research Identifying and Characterizing Eosinophils
https://clinicaltrials.gov/ct2/show/NCT04538937

Sep 4th, 2020 - Introduction: The etiology and therapy of eosinophilic lung diseases are still poorly understood. For individual forms of disease, such as eosinophilic asthma or eosinophilic granulomatosis with polyangiitis (EGPA), new therapeutic approaches exis...

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News  5 results

Dr. Mesa on Upcoming Updates to NCCN Guideline for MPNs
https://www.onclive.com/view/dr-mesa-on-upcoming-updates-to-nccn-guideline-for-mpns

Dec 20th, 2020 - Ruben A. Mesa, MD, chair of Hematology, Mayo Clinic, discusses updates that are expected in 2017 to the NCCN Guideline for Myeloproliferative Neoplasms (MPNs). The NCCN Guidelines for Myeloproliferative Neoplasms (version 1.2017), which include t...

FDA OKs Mepolizumab (Nucala) for Hypereosinophilic Syndrome
https://www.medscape.com/viewarticle/938221

Sep 28th, 2020 - The US Food and Drug Administration (FDA) has expanded the indication for mepolizumab (Nucala, GlaxoSmithKline) to include patients with hypereosinophilic syndrome (HES). Mepolizumab is indicated for adults and children aged 12 years and older wit...

FDA OKs Mepolizumab (Nucala) for Hypereosinophilic Syndrome
https://www.staging.medscape.com/viewarticle/938221

Sep 28th, 2020 - The US Food and Drug Administration (FDA) has expanded the indication for mepolizumab (Nucala, GlaxoSmithKline) to include patients with hypereosinophilic syndrome (HES). Mepolizumab is indicated for adults and children aged 12 years and older wit...

FDA approves generic imatinib
https://www.mdedge.com/hematology-oncology/article/188490/cythemias/fda-approves-generic-imatinib
HT Staff

Dec 6th, 2015 - Prescription drugs Photo by Steven Harbour The US Food and Drug Administration (FDA) has approved the use of imatinib mesylate, a generic version of Novartis’s Gleevec being developed by a subsidiary of Sun Pharmaceuticals Limited. Under the terms.

Eosinophilic Esophagitis: New Guidelines
https://www.medscape.com/viewarticle/806908_2

Jul 8th, 2013 - Making the Diagnosis The diagnosis of EoE is not uncommon. We didn't see EoE 2 decades ago, but the condition is now being increasingly recognized. Slide 3. (Enlarge Slide) The presentation varies according to age. In adults, 34%-50% of patients p...

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Patient Education  3 results see all →