About 1,723 results

ALLMedicine™ Chronic Urticaria Center

Research & Reviews  391 results

Local inflammation enables a basophil-neuronal circuITCH in atopic dermatitis.
Allergy López-Sanz C, Jimenéz-Saiz R et. al.

Jul 29th, 2021 - Allergic inflammation is often the result of a dysregulated Th2 immune response, IgE production, and the release of allergic mediators such as histamine or leukotrienes (LTs) by basophils and mast cells (MCs). Allergic diseases can manifest as acu...

Basophil Activation Test for Allergy Diagnosis.
Journal of Visualized Experiments : JoVE; Doña I, Ariza A et. al.

Jun 15th, 2021 - The basophil activation test (BAT) is a complementary in vitro diagnostic test that can be used in addition to clinical history, skin test (ST), and specific IgE (sIgE) determination in the evaluation of IgE-mediated allergic reactions to food, in...

Approach to Children with Hives.
Pediatric Annals; Poowuttikul P, Pansare M et. al.

May 29th, 2021 - Urticaria (or hives) is a pruritic and erythematous skin rash. Angioedema commonly occurs with urticaria. The term "chronic urticaria" is used when hives are present for more than 6 weeks. Acute urticaria is common in children, whereas chronic urt...

Effects of pregnancy on chronic urticaria: Results of the PREG-CU UCARE study.
Allergy Kocatürk E, Al-Ahmad M et. al.

May 23rd, 2021 - Chronic urticaria (CU) predominantly affects women, and sex hormones can modulate disease activity in female CU patients. As of now, the impact of pregnancy on CU is largely unknown. To analyze the course and features of CU during and after pregna...

Improvement of patient outcomes following therapeutic optimization of chronic urticaria...
European Journal of Dermatology : EJD; Giordano-Labadie F, Becherel PA et. al.

May 19th, 2021 - It is important to assess the burden of chronic urticaria (CU) with real-life studies. The AWARE study was performed in 36 countries over two years in CU patients resistant to H1-antihistamines. To correlate patient-reported outcomes and available...

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Drugs  227 results see all →

Clinicaltrials.gov  23 results

Mepolizumab for the Treatment of Chronic Spontaneous Urticaria

Aug 15th, 2018 - This is an open-label, single arm exploratory study of mepolizumab in the treatment of CSU. The primary endpoint will be the mean reduction in the seven day urticaria activity score (UAS7) before and after 10 weeks of treatment with mepolizumab. S...

COrticosteroids in acUte uRticAria in emerGency dEpartment

Jun 4th, 2018 - Acute urticaria (hives) is a common skin disease. The prevalence of acute urticaria in life is about 15 to 20% in the general population. It is responsible for a frequent use of emergency departments (ED). The usual treatment is based on early adm...

AWARE - Chronic Urticaria

Feb 15th, 2018 - Non interventional study collecting patient reported outcomes. The study aims to assess the disease burden of chronic urticaria patients and to record the therapies used in daily clinical practice in the UK and the impact they have on the quality ...

An Efficacy and Safety Study of Desloratadine (MK-4117) in Japanese Participants With Chronic Urticaria (MK-4117-201)

Oct 18th, 2017 - This is a study to evaluate the efficacy and safety of desloratadine (MK-4117) in Japanese participants with chronic urticaria. The primary hypothesis is that the efficacy of desloratadine 10 mg and 5 mg is superior to placebo as based on the chan...

The Role of Vitamin D in Chronic Urticaria and Angioedema Treatment

Sep 28th, 2017 - The purpose of this pilot, 12 week, clinical research study is to determine if supplementation with Vitamin D will improve the clinical outcome in subjects with chronic urticaria and angioedema (CUA). Vitamin D is a key element in the regulation o...

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News  48 results

Swedish Registry Study Finds Atopic Dermatitis Significantly Associated With Autoimmune Diseases

Jan 5th, 2021 - A diagnosis of atopic dermatitis in individuals ages 15 years or older, compared with controls without atopic dermatitis, was nearly twice as likely to be associated with autoimmune disease, in a case control study derived from Swedish national he...

Fast Five Quiz: Chronic Spontaneous Urticaria

Jun 15th, 2020 - Both the American Academy of Allergy, Asthma, and Immunology (AAAAI) and the European Academy of Allergy and Clinical Immunology (EAACI)/Global Allergy and Asthma European Network (GA2LEN)/European Dermatology Forum (EDF)/World Allergy Organizatio...

Fast Five Quiz: Chronic Spontaneous Urticaria

Jun 15th, 2020 - Chronic spontaneous urticaria (CSU) (also referred to as "chronic idiopathic urticaria") represents the majority of cases of chronic urticaria. CSU is defined as chronic urticaria of known or unknown etiology lasting for ≥ 6 weeks. In a subset of ...

Ligelizumab May Improve Response in Chronic Urticaria

Oct 3rd, 2019 - In the fight against chronic hives, the humanized anti-IgE monoclonal antibody ligelizumab may pack a more powerful punch than omalizumab (Xolar, Genentech), the previous top contender for trapping IgE antibodies for patients with chronic spontane...

Antihistamines May Help Some Patients With Chronic Diarrhea

Jul 24th, 2019 - Some patients with idiopathic postprandial diarrhea (PPD) may respond to antihistamine treatment, according to a recent case series published online in Annals of Allergy, Asthma & Immunology. "Antihistamine-responsive PPD is seen in patients with ...

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