About 374 results
Asthma in Adults
Medical Clinics of North America; Nanda A, et al

Oct 27th, 2019 - Asthma affects approximately 300 million people worldwide and approximately 7.5% of adults in the United States. Among adults, asthma results in about 10.5 million physician office visits per year and affects approximately 8.7% of blacks, 7.6% of whites, and 5.8% of Hispanics. Asthma is characterized by inflammation of airways, variable airflow obstruction, and bronchial hyperresponsiveness.3 I...

Genentech Announces FDA Approval of Xofluza (Baloxavir Marboxil) for People at High Risk of Developing Influenza-Related Complications

Oct 16th, 2019 - Single-dose Xofluza is the first and only antiviral medicine indicated specifically for patients at high risk of developing serious complications from influenza (flu) The Centers for Disease Control and Prevention (CDC) defines people at high risk of serious flu complications as those who have conditions such as asthma, chronic lung disease, diabetes, heart disease, morbid obesity or adults ...

Predicting the Risk of Postoperative Pulmonary Complications
American Family Physician;

Oct 14th, 2019 - The incidence of pulmonary complications following major surgery is estimated to be 1% to 23%, with the risk varying based on patient factors and the type of surgery.1 Postoperative pulmonary complications include pneumonia, tracheobronchitis, pulmonary edema, pulmonary embolism, atelectasis, pleural effusion, pneumothorax, bronchospasm, aspiration, respiratory failure, and acute respiratory di...

Global Initiative for Asthma: Global Strategy for Asthma Management & Prevention

Sep 29th, 2019 - The 2019 update of the Global Strategy for Asthma Management and Prevention incorporates new scientific information about asthma based on a review of recent scientific literature by an international panel of experts on the GINA Science Committee. This comprehensive and practical resource about one of the most common chronic lung diseases worldwide contains extensive citations from the scientifi...

Can Mild Asthma Be Managed with Only As-Needed Inhaled Steroids Plus a Bronchodilator?

Sep 25th, 2019 - David J. Amrol, MD reviewing Hardy J et al. Lancet 2019 Sep 14 Gauthier M and Wenzel SE. Lancet 2019 Sep 14

Are Antihistamines and Steroids Helpful for Anaphylaxis?

Sep 23rd, 2019 - David J. Amrol, MD reviewing Gabrielli S et al. J Allergy Clin Immunol Pract 2019 Sep/Oct

FDA Allergenic Products Advisory Committee Votes to Support the Use of Aimmune’s PALFORZIA™ (AR101) for Peanut Allergy

Sep 12th, 2019 - Aimmune Therapeutics, Inc. (Nasdaq:AIMT), a biopharmaceutical company developing treatments for potentially life-threatening food allergies, today announced that the Allergenic Products Advisory Committee (APAC) convened by the U.S. Food and Drug Administration (FDA) voted to support the use of AR101 (proposed trade name PALFORZIA™) in children and teens with peanut allergy. PALFORZIA is a comp...

Nucala is the first biologic approved in the US for six to 11-year-old children with severe eosinophilic asthma

Sep 11th, 2019 - GlaxoSmithKline (LSE/NYSE: GSK) today announced that the US Food and Drug Administration (FDA) has approved Nucala (mepolizumab) for use in children as young as six years old who are living with severe eosinophilic asthma. Nucala is the only targeted biologic to be approved for the condition in the six to 11-year age group in the US.

Scientists discover immune cell subtype in mice that drives allergic reactions

Jul 31st, 2019 - Allergies can be life-threatening when they cause anaphylaxis, an extreme reaction with constriction of the airways and a sudden drop in blood pressure. Scientists have identified a subtype of immune cell that drives the production of antibodies (link is external) associated with anaphylaxis and other allergic reactions. The research was funded by the National Institute of Allergy and Infectio...

Clinical trial to evaluate experimental treatment in people allergic to multiple foods

Jul 31st, 2019 - Though food allergy affects more than 4.8 million children in the United States, no approved preventative treatments currently exist. While experimental desensitization strategies are available in research settings, people with food allergies must avoid known allergens and are advised to carry injectable epinephrine to prevent potentially life-threatening allergic reactions caused by accidenta...

Risk of Acute Myocardial Infarction and Ischemic Stroke in Patients with Asthma Exacerbation: A Population-Based, Self-Controlled Case Series Study
The Journal of Allergy and Clinical Immunology: In Practice; Raita, Y. et. al.

Jul 15th, 2019 - Background Patients with asthma have a high incidence of acute myocardial infarction and ischemic stroke. Objective To investigate the acute effect of asthma exacerbation on these cardiovascular events. Methods Using population-based inpatient data of 3 geographically diverse US states (Florida, Nebraska, and New York) during the period 2011 to 2014, we conducted a self-controlled case...

Teva Announces FDA Approval of AirDuo® Digihaler™ (fluticasone propionate 113 mcg and salmeterol 14 mcg) Inhalation Powder

Jul 14th, 2019 - Teva Pharmaceutical Industries Ltd. (NYSE and TASE: TEVA) announced today that the U.S. Food and Drug Administration (FDA) has approved AirDuo® Digihaler™ (fluticasone propionate 113 mcg and salmeterol 14 mcg) Inhalation Powder, a combination therapy digital inhaler with built-in sensors that connects to a companion mobile application to provide information on inhaler use to people with asthma....

Grifols announces FDA approval of Xembify®, 20% subcutaneous immunoglobulin for primary immunodeficiencies

Jul 4th, 2019 - Grifols (MCE:GRF, MCE:GRF.P NASDAQ:GRFS), a leading global producer of plasma-derived medicines, announced today that Xembify®, its new 20% subcutaneous immunoglobulin, has been approved by the U.S. Food and Drug Administration (FDA). Xembify® is used to treat primary immunodeficiencies.

Clinical Trials | NUCALA (mepolizumab)

Jun 26th, 2019 - NUCALA (mepolizumab) has clinical data on exacerbation reduction. Learn about NUCALA for patients with severe eosinophilic asthma.

Atopic dermatitis/Eczema | DermNet NZ

Jun 24th, 2019 - Atopic dermatitis is a chronic, itchy skin condition that is very common in children but may occur at any age. It is also known as eczema and atopic eczema and was formerly known as Besnier prurigo. It is the most common form of dermatitis. Atopic dermatitis usually occurs in people who have an 'atopic tendency'. This means they may develop any or all of three closely linked conditions; atop...

Eczema - StatPearls
Nemeth, V. et. al.

Jun 3rd, 2019 - Eczema, also known as atopic dermatitis, is the most common form of dermatitis. Genetic as well as environmental factors are thought to play a part in the pathogenesis. Eczema is most commonly seen in children but can be seen in adults. People with the disease tend to have dry, itchy skin that is prone to infection. Eczema is commonly known as the "itch that rashes" due to dry skin that lea...

Head‐to‐head oral prophylactic antibiotic therapy for chronic obstructive pulmonary disease
The Cochrane Database of Systematic Reviews; Threapleton, C. et. al.

May 23rd, 2019 - Chronic obstructive pulmonary disease (COPD; including chronic bronchitis and emphysema) is a chronic respiratory condition characterised by shortness of breath, cough and recurrent exacerbations. Long‐term antibiotic use may reduce both bacterial load and inflammation in the airways. Studies have shown a reduction of exacerbations with antibiotics in comparison to placebo in people with COPD, ...

Rate of life-threatening childbirth complications increasing sharply across U.S. racial, ethnic groups

May 2nd, 2019 - Racial and ethnic disparities in severe maternal morbidity — life-threatening maternal complications associated with childbirth — have persisted and increased at high rates among U.S. women, according to an analysis of nearly 20 years of California hospital records funded by the National Institutes of Health. Known risk factors for these complications — such as blood pressure disorders, asthma ...

Interventions for hand eczema
The Cochrane Database of Systematic Reviews; Christoffers, W. et. al.

Apr 25th, 2019 - Hand eczema is an inflammation of the skin of the hands that tends to run a chronic, relapsing course. This common condition is often associated with itch, social stigma, and impairment in employment. Many different interventions of unknown effectiveness are used to treat hand eczema.

Asthma Data, Statistics, and Surveillance

Mar 24th, 2019 - The latest national and state data on the burden of asthma among children and adults.

Clinical Practice Guideline for the Management of Asymptomatic Bacteriuria: 2019 Update by t...

Mar 20th, 2019 - Asymptomatic bacteriuria (ASB) is a common finding in many populations, including healthy women and persons with underlying urologic abnormalities. The 2005 guideline from the Infectious Diseases Society of America recommended that ASB should be screened for and treated only in pregnant women or in an individual prior to undergoing invasive urologic procedures.

The Effects of Early Nutritional Interventions on the Development of Atopic Disease in Infants and Children: The Role of Maternal Dietary Restriction, Breastfeeding, Hydrolyzed Formulas, and Timing...

Mar 17th, 2019 - This clinical report updates and replaces a 2008 clinical report from the American Academy of Pediatrics, which addressed the roles of maternal and early infant diet on the prevention of atopic disease, including atopic dermatitis, asthma, and food allergy. As with the previous report, the available data still limit the ability to draw firm conclusions about various aspects of atopy prevention ...

Asthma More Common in Opioid-Dependent Patients
Boyles, S.

Feb 23rd, 2019 - The prevalence of asthma was nearly twice as high as the national average in a cohort of opioid-dependent patients receiving acute care at an inner city hospital in a New York City borough, with female sex more closely linked to higher asthma risk than male sex, researchers reported here.

Coverage from the American Academy of Allergy, Asthma and Immunology (AAAAI) 2019 Meeting

Feb 21st, 2019 - American Academy of Allergy, Asthma and Immunology (AAAAI) 2019 Meeting: Read clinically focused news coverage of key developments from AAAAI 2019

The Asthma Controller Step-down Yardstick
Chipps, B.,et al

Dec 10th, 2018 - Asthma guidelines recommend a control-based approach to disease management in which the assessment of impairment and risk is linked to step-based therapy. Using this model, controller treatment is adjusted—upward or downward—according to a patient's level of asthma control over time.

Systemic Mastocytosis, Version 2.2019, NCCN Clinical Practice Guidelines in Oncology
Gotlib, J.

Nov 30th, 2018 - Mastocytosis is a group of heterogeneous disorders resulting from the clonal proliferation of abnormal mast cells and their accumulation in the skin and/or in various extracutaneous organs. Systemic mastocytosis is the most common form of mastocytosis diagnosed in adults, characterized by mast cell infiltration of one or more extracutaneous organs (with or without skin involvement).


Nov 12th, 2018 - Evidence-based update using Cochrane Eyes and Vision Group-identified systematic reviews for the initial evaluation of conjunctivitis patients and discussion of associated or predisposing factors.

Efficacy, adverse events, and inter-drug comparison of mepolizumab and reslizumab anti-IL-5 treatments of severe asthma – a systematic review and meta-analysis
European Clinical Respiratory Journal;

Nov 6th, 2018 - Background: New, complex, and expensive therapies targeting Interleukin-5 (IL-5) to treat severe eosinophilic asthma are emerging. Objective: To assess efficacy, adverse events, and inter-drug comparison of mepolizumab and reslizumab for treating severe eosinophilic asthma. Design: A systematic review and meta-analysis on randomized, placebo-controlled, clinical trials elucidating two cri...

Clinical Guideline for the Diagnosis, Evaluation and Management of Adults and Children with Asthma

Nov 3rd, 2018 - Consider a diagnosis of asthma and perform spirometry if any of these indicators are present :The symptoms of dyspnea, cough and/or wheezing, especially nocturnal, difficulty breathing or chest tightness

Antimicrobial Prophylaxis for Adult Patients With Cancer-Related Immunosuppression: ASCO and IDSA Clinical Practice Guideline Update
Taplitz, R. et. al.

Sep 3rd, 2018 - Antibacterial and antifungal prophylaxis is recommended for patients who are at high risk of infection, including patients who are expected to have profound, protracted neutropenia, which is defined as < 100 neutrophils/µL for > 7 days or other risk factors. Herpes simplex virus–seropositive patients undergoing allogeneic hematopoietic stem-cell transplantation or leukemia induction therapy sho...

Eosinophilic Asthma | Apfed

Jun 25th, 2018 - For decades physicians have understood that a diagnosis of asthma requires further description because attacks of wheezing and shortness of breath can be associated with several underlying diseases. For example, patients allergic to animal dander, such as cat dander, who have animals as pets, may suffer from chronic severe asthma. Identification of patients with this form of asthma (referred to...

Asthma for Healthcare Professionals | CDC

Jun 18th, 2018 - Vital Signs: Asthma in Children – United States, 2001-2016 Free continuing education (CE) activity that describes trends and demographic differences in health outcomes and healthcare use for childhood asthma, based on a CDC analysis of asthma data from the 2001-2016 National Health Interview Survey for children 17 years and younger.This activity is intended for pediatricians, pulmonologists, ...

Asthma Risk Factors | American Lung Association

May 20th, 2018 - The most common risk factors for developing asthma is having a parent with asthma, having a severe respiratory infection as a child, having an allergic condition, or being exposed to certain chemical irritants or industrial dusts in the workplace.

Outpatient Management of Fever and Neutropenia in Adults Treated for Malignancy
Randy A. Taplitz

May 9th, 2018 - To provide an updated joint ASCO/Infectious Diseases Society of American (IDSA) guideline on outpatient management of fever and neutropenia in patients with cancer.

Asthma as the Underlying Cause of Death | CDC

Apr 23rd, 2018 - Asthma deaths have decreased over time and varied by demographic characteristics. View the statistics from the Centers for Disease Control and Prevention (CDC) - National Center of Environmental Health (NCEH) - National Asthma Control Program

Current Asthma Prevalence by Weight Status Among Adults: United States, 2001–2014

Mar 15th, 2018 - Asthma is a common chronic airway disorder characterized by periods of airflow obstruction known as asthma attacks (1). Symptom frequency can range from intermittent to constant, and attack severity can vary from mild to life threatening (1). Several studies have shown that among adults, obesity is associated with an increased risk of asthma diagnosis, more frequent asthma-related health care u...

Asthma Statistics- Facts and Figures

Feb 16th, 2018 - Asthma statistics: Approximately 25.9 million Americans suffer from asthma. It is one of this country's most common and costly diseases.

Percentage of People with Asthma who Smoke

Jan 30th, 2018 - Nearly 17% of people without asthma smoke. But surprisingly, even more people with asthma smoke. About 21% of people with asthma smoke, even though cigarette smoke is known to trigger asthma attacks.

Practice Guidelines for Peanut Allergies
Sitton, C.,et al.

Dec 31st, 2017 - This article reviews the latest recommendations and clinical practice guidelines for peanut allergies among the pediatric population. Recommendations in this paper were compiled using information collected from a variety of publications of accredited professional organizations.

Pharmacologic Treatment of Seasonal Allergic Rhinitis: Synopsis of Guidance From the 2017 Jo...
Wallace, D.,et al

Dec 18th, 2017 - The Joint Task Force on Practice Parameters, which comprises representatives of the American Academy of Allergy, Asthma and Immunology (AAAAI) and the American College of Allergy, Asthma and Immunology (ACAAI), formed a workgroup to review evidence and provide guidance to health care providers on the initial pharmacologic treatment of seasonal allergic rhinitis in patients aged 12 years or older.

Myeloid Growth Factors, Version 2.2017, NCCN Clinical Practice Guidelines in Oncology
Crawford, J.,et al

Nov 30th, 2017 - Myeloid growth factors (MGFs) are given as supportive care to patients receiving myelosuppressive chemotherapy to reduce the incidence of neutropenia. This selection from the NCCN Guidelines for MGFs focuses on the evaluation of regimen- and patient-specific risk factors for the development of febrile neutropenia (FN), the prophylactic use of MGFs for the prevention of chemotherapy-induced FN,.

Asthma - Lab Tests

Oct 24th, 2017 - Asthma is a chronic inflammatory condition affecting the lungs. With asthma, the tubes that carry air throughout the lungs (bronchi) are inflamed and swollen, which narrows the airway and makes it more difficult to breathe. Learn about the lab tests used to help diagnose, monitor, and manage asthma.

Presentations and Discussion of the Sixth Jack Pepys Workshop on Asthma in the Workplace
Susan M. Tarlo

Aug 31st, 2017 - The Sixth Jack Pepys Workshop on Asthma in the Workplace focused on six key themes regarding the recognition and assessment of work-related asthma and airway diseases: (1) cleaning agents and disinfectants(includinginswimmingpools)asirritantsandsensitizers: how to evaluate types of bronchial reactions and reduce risks, (2) population-based studies of occupational obstructive diseases: use of da.

Asthma Clinical Resources

Aug 31st, 2017 - Pathogenenesis of viral infection in exacerbations of airway disease

Sodium Intake and Health Outcomes
Strom, B. et. al.

Aug 26th, 2017 - This chapter reviews and assesses new evidence for associations between dietary sodium intake and outcomes published in the peer-reviewed literature through 2012. The health outcomes reviewed by the committee include cardiovascular disease (CVD), including stroke CVD mortality and all-cause mortality, congestive heart failure (CHF), chronic kidney disease (CKD), diabetes, cancer, and “other” ou...

Treatment of seasonal allergic rhinitis
Dykewicz, M.

Jul 31st, 2017 - Allergic rhinitis (AR) is a prevalent disorder responsible for a significant and often underappreciated health burden for individuals and society (see Burden of Disease section). Guidelines to improve care for patients with AR have been evolving in an effort to respond to the introduction of new treatment approaches, to address the availability of additional studies that compare treatment optio.

Work-related Asthma Epidemiology - CDC

May 23rd, 2017 - Work-related asthma is the most prevalent occupational lung disease and is likely underrecognized in the clinical setting. Thus, a thorough occupational history is critical for identifying patients.

Mechanical Ventilation in Adult Patients with Acute Respiratory Distress Syndrome
Eddy Fan

Apr 30th, 2017 - The panel formulated and provided the rationale for recommendations on selected ventilatory interventions for adult patients with ARDS. Clinicians managing patients with ARDS should personalize decisions for their patients, particularly regarding the conditional recommendations in this guideline.

International consensus guidelines for the diagnosis and management of food protein–induced ...
Anna Nowak-Wegrzyn

Mar 31st, 2017 - These are the first international evidence-based guidelines to improve the diagnosis and management of patients with FPIES.

National Center for Health Statistics - Asthma

Jan 18th, 2017 - FastStats is an official application from the Centers for Disease Control and Prevention & (CDC) National Center for Health Statistics (NCHS) and puts access to topic-specific statistics at your fingertips.

The Lung Association calls for action to reduce Misdiagnosis of asthma
Canadian Lung Association

Jan 16th, 2017 - New research published in the Journal of American Medical Association demonstrates that people are continuing to be misdiagnosed with asthma. The findings published in the study – Reevaluation of Diagnosis in Adults with Physician-Diagnosed Asthma - show that 33 per cent of those recently diagnosed with asthma do not have it.

An Official American Thoracic Society Research Statement: Current Challenges Facing Research...
Y. S. Prakash

Jan 14th, 2017 - Airway remodeling (AR) is a prominent feature of asthma and other obstructive lung diseases that is minimally affected by current treatments. The goals of this Official American Thoracic Society (ATS) Research Statement are to discuss the scientific, technological, economic, and regulatory issues that deter progressof AR research and development of therapeutics targeting AR and to propose appro.

Dietary Therapy and Nutrition Management of Eosinophilic Esophagitis: A Work Group Report of...
Marion Groetch

Dec 20th, 2016 - This work group report addresses the potential challenges of implementing an elimination diet for the management of EoE and provides instructions and tools for physicians, dietitians, and other allied health professionals to help guide them in planning elimination diets for both children and adult.

Something new in the air: Paying for community-based environmental approaches to asthma prev...
Megan M. Tschudy

Dec 5th, 2016 - Although traditional health care payment models have not covered the costs of home-based environmental interventions, there are emerging payment models that cover these costs, and our work group was tasked with developing this report to educate health care providers about these emerging payment models.

An Official American Thoracic Society Workshop Report: Evaluation and Management of Asthma i...
Gwen S. Skloot

Oct 31st, 2016 - Asthma in the elderly (>65 yr old) is common and associated with higher morbidity and mortality than asthma in younger patients. The poor outcomes in this group are due, in part, to underdiagnosis and undertreatment.

Role of the Allergist-Immunologist and Upper Airway Allergy in Sleep-Disordered Breathing: A...
Shusterman D

Oct 2nd, 2016 - Objectives: To survey active American Academy of Allergy, Asthma & Immunology members regarding their perceptions and practices concerning sleep-disordered breathing in adult and pediatric patients with rhinitis, and to review the medical literature concerning this connection to identify therapeutic implications and research gaps.

A work group report on ultrafine particles (American Academy of Allergy, Asthma & Immunology...
Li N, Georas S et. al.

Jul 31st, 2016 - A work group report on ultrafine particles. The objective of this article is to provide an up-to-date report on the effect of UFPs on human health and potential nanomaterial hazards.

The frequency of asthma exacerbations and healthcare utilization in patients with asthma from the UK and USA
BMC Pulmonary Medicine;

Jul 21st, 2016 - Asthma exacerbations are frequent in patients with severe disease. This report describes results from two retrospective cohort studies describing exacerbation frequency and risk, emergency department (ED)/hospital re-admissions, and asthma-related costs by asthma severity in the US and UK.

Practice Guidelines for the Diagnosis and Management of Aspergillosis: 2016 Update by the In...
Thomas F. Patterson

Jun 25th, 2016 - Aspergillus species continue to be an important cause of life-threatening infection in immunocompromised patients. This at-risk population is comprised of patients with prolonged neutropenia, allogeneic hematopoietic stem cell transplant (HSCT), solid organ transplant (SOT), inherited or acquired immunodeficiencies, corticosteroid use, and others.

Creation and implementation of SAMPROTM: A school-based asthma management program:AAAAI Guid...
Robert F. Lemanske, Jr et. al.

Jun 2nd, 2016 - Clinicians who care for children with asthma have an obligation to coordinate asthma care with the schools. Aside from routine clinical care of asthmatic children, providers must educate the family and child about the need for an asthma treatment plan in school and support the school nurse meeting the needs of the student requiring school-based asthma care.

Exercise-induced bronchoconstrictionupdate—2016
Weiler, J.

Apr 30th, 2016 - The first practice parameter on exercise-induced bronchoconstriction (EIB) was published in 2010. This updated practice parameter was prepared 5 years later.

Anaphylaxis- practice parameter update 2015
Lieberman, P.

Oct 31st, 2015 - The Joint Task Force on Practice Parameters (JTF) is a 13-member task force consisting of 6 representatives assigned bythe American Academy of Allergy, Asthma & Immunology, 6 bythe American College of Allergy, Asthma & Immunology, and 1 bythe Joint Council of Allergy and Immunology. This JTF oversees thedevelopment of practice parameters, selects the workgroupchair(s), and reviews drafts of the.

Practice parameter for the diagnosis and managementof primary immunodeficiency
Bonilla, F.

Oct 31st, 2015 - The American Academy of Allergy, Asthma & Immunology (AAAAI) and the American College of Allergy, Asthma & Immunology (ACAAI) have jointly accepted responsibility for establishing the "Practice parameter for the diagnosis and management of primary immunodeficiency. " This is a complete and comprehensive document at the current time.

Causes and Evaluation of Chronic Dyspnea

Jul 11th, 2015 - Chronic dyspnea is shortness of breath that lasts more than one month. The perception of dyspnea varies based on behavioral and physiologic responses. Dyspnea that is greater than expected with the degree of exertion is a symptom of disease. Most cases of dyspnea result from asthma, heart failure and myocardial ischemia, chronic obstructive pulmonary disease, interstitial lung disease, pneumoni...

Presentations and Discussion of the Fifth Jack Pepys Workshop on Asthma in the Workplace
Jean-Luc Malo

Jun 30th, 2015 - The fifth Jack Pepys Workshop on Asthma in the Workplace focused on the similarities and differences of work-related asthma (WRA) and non-work-related asthma (non-WRA). WRA includes occupational asthma (OA) and work-exacerbated asthma (WEA).

The Canadian Lung Association applauds a new law that allows kids in Ontario with asthma to ...
Canadian Lung Association

Apr 29th, 2015 - The Canadian Lung Association applauds the Ontario Legislature for passing a new law that allows children with asthma to carry asthma inhalers at school and would require school boards to develop a comprehensive asthma policy.

Clinical Practice Guideline: Allergic Rhinitis
Michael D. Seidman

Feb 1st, 2015 - Allergic rhinitis (AR) is one of the most common diseases affecting adults. It is the most common chronic disease in children in the United States today and the fifth most common chronic disease in the United States overall.

Emergency department diagnosis and treatment of anaphylaxis:a practice parameter
Campbell, R.

Nov 30th, 2014 - This practice parameter is a joint effort between emergency physicians, who are often on the front line in the management ofanaphylaxis, and allergists-immunologists, who have a vested interest in how such patients are managed. As recognized by emergency physicians and allergists, the timely administration of epinephrine is essential to the effective treatment of anaphylaxis,and such administra.

Physician Implementation of Asthma Management Guidelines and Recommendations: 2 Case Studies
D. Parker Jonathan

Oct 31st, 2014 - Despite the development and availability of new treatments and prescription medications, asthma remains a widespread chronic health problem in the United States. Achieving asthma control in patients is a resource-intensive enterprise that requires close assessment and personalized management.

Management of acute loss of asthma control in the yellow zone:a practice parameter
Dinakar, C.

Jul 31st, 2014 - The Yellow Zone Practice Parameter Workgroup was commissionedby the JTF to develop practice parameters that addressmanagement of acute loss of asthma control in the yellow zone. Thechair (Chitra Dinakar, MD) invited workgroup members to participatein the parameter development who are considered experts inthe field of asthma management.

Practice Guidelines for the Diagnosis and Management of Skin and Soft Tissue Infections: 201...
Dennis L. Stevens

Jul 14th, 2014 - A panel of national experts was convened by the Infectious Diseases Society of America (IDSA) to update the 2005 guidelines for the treatment of skin and soft tissue infections (SSTIs). The panel's recommendations were developed to be concordant with the recently published IDSA guidelines for the treatment of methicillin-resistant Staphylococcus aureus infections.

The diagnosis and management of acute and chronic urticaria: 2014 update
Bernstein, J.

Apr 30th, 2014 - Theworkgroup was formed by the JTFPP to develop a practiceparameter to address the diagnosis and treatment of urticaria withor without angioedema. The chair, Jonathan Bernstein, MD,invited workgroup members to participate in the parameterdevelopment.

Diagnosis and management of eosinophilic asthma: a US perspective
Journal of Asthma and Allergy;

Apr 10th, 2014 - Eosinophilic asthma is now recognized as an important subphenotype of asthma based on the pattern of inflammatory cellular infiltrate in the airway. Eosinophilic asthma can be associated with increased asthma severity, atopy, late-onset disease, and steroid refractoriness. Induced sputum cell count is the gold standard for identifying eosinophilic inflammation in asthma although several noninva...

Consensus statement on the diagnosis, treatment and follow-up of patients with primary adren...
Husebye, E.

Jan 31st, 2014 - Primary adrenal insufficiency (PAI), or Addison's disease, is a rare, potentially deadly, but treatable disease. Most cases of PAI are caused by autoimmune destruction of the adrenal cortex.

International ERS/ATS Guidelines on Definition, Evaluation and Treatment of Severe Asthma
Kian Fan Chung

Jan 31st, 2014 - Coordinated research efforts for improved phenotyping will provide safe and effective biomarker-driven approaches to severe asthma therapy.

International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma
Kian Fan Chung

Jan 31st, 2014 - The European Respiratory Society (ERS)/American Thoracic Society (ATS) Task Force on severe asthma includes an updated definition of severe asthma, a discussion of severe asthma phenotypes in relation to genetics, natural history, pathobiology and physiology, as well as sections on evaluation and treatment of severe asthma where specific recommendations for practice are made.

Environmental assessment and exposure reduction of cockroaches: A practice parameter
Portnoy, J.

Sep 30th, 2013 - This parameter was developed by the Joint Task Force on Practice Parameters, representing the American Academy of Allergy, Asthma & Immunology (AAAAI), the American College of Allergy, Asthma & Immunology (ACAAI), and the Joint Council of Allergy, Asthma & Immunology. The AAAAI and the ACAAI have jointly accepted responsibility for establishing "Environmental assessment and remediation: a pract.

An Official American Thoracic Society Proceedings: Work-related Asthma and Airway Diseases
Susan M. Tarlo, Jean-Luc Malo

Jul 31st, 2013 - Work-related asthma is a common occupational lung disease. The scope of the Fourth Jack Pepys Workshop that was held in May 2010 went beyond asthma to include discussion of other occupational airway diseases, in particular occupationally related chronic obstructive pulmonary disease (COPD) and bronchiolitis.

Clinical Practice Guideline for the Diagnosis and Management of Acute Bacterial Sinusitis in...
Wald, E.

Jun 30th, 2013 - To update the American Academy of Pediatrics clinical practice guideline regarding the diagnosis and management of acute bacterial sinusitis in children and adolescents.

An Official American Thoracic Society Clinical Practice Guideline: Exercise-induced Bronchoc...
Jonathan P. Parsons

Apr 30th, 2013 - Exercise-induced bronchoconstriction (EIB) describes acute airway narrowing that occurs as a result of exercise. A substantial proportion of patients with asthma experience exercise-induced respiratory symptoms.

Allergic conjunctivitis: a comprehensive review of the literature
Italian Journal of Pediatrics; La Rosa, M. et. al.

Mar 13th, 2013 - Ocular allergy represents one of the most common conditions encountered by allergists and ophthalmologists. Allergic conjunctivitis is often underdiagnosed and consequently undertreated. Basic and clinical research has provided a better understanding of the cells, mediators, and immunologic events, which occur in ocular allergy. New pharmacological agents have improved the efficacy and safety o...

A focused parameter update: Hereditary angioedema,acquired C1 inhibitor deficiency, and angi...
Zuraw, B.

Feb 28th, 2013 - Hereditary angioedema (HAE) usually results from a deficiencyof the serine protease inhibitor C1 inhibitor (C1INH). (LB)There are 2 types of HAE, type I is most common.

Atopic dermatitis: A practice parameter update 2012
Schneider, L.

Nov 30th, 2012 - Atopic dermatitis (AD) is often the first manifestation ofallergic disease. Most patients with AD will also have anotheratopic disorder, such as allergic rhinitis, asthma, or foodallergy.

Guideline for the Management of Fever and Neutropenia in Children With Cancer and/or Undergo...
Thomas Lehrnbecher

Feb 29th, 2012 - This guideline represents an evidence-based approach to FN specific to children with cancer. Although some recommendations are similar to adult-based guidelines, there are key distinctions in multiple areas.

Screening for Obesity in Children and Adolescents: US Preventive Services Task Force Re...
JAMA , Grossman DC et. al.

Jun 20th, 2017 - Based on year 2000 Centers for Disease Control and Prevention growth charts, approximately 17% of children and adolescents aged 2 to 19 years in the United States have obesity, and almost 32% of children and adolescents are overweight or have obesity. Obesity in children and adolescents is associated with morbidity such as mental health and psychological issues, asthma, obstructive sleep apnea,...

What is the Emergency Department Management of Patients with Angioedema Secondary to an ACE-...
Michael Winters, Steven Rosenbaum

Apr 10th, 2011 - The current literature on ACE-inhibitor angioedema is primarily limited to retrospective reviews, case series, and case reports. Based upon this review of the literature, ACE-inhibitor angioedema should be considered in any ED patient presenting with asymmetric swelling of the lips, tongue, floor of the mouth, face, neck or eyelids.

Guidelines for the Diagnosis and Management of Food Allergy in the United: States Summary of the NIAID-Sponsored Expert Panel Report
National Institute of Allergy and Infectious Diseases

Dec 16th, 2010 - Food allergy (FA) is an important public health problem that affects adults and children and may be increasing in prevalence. Despite the risk of severe allergic reactions and even death, there is no current treatment for FA: the disease can only be managed by allergen avoidance or treatment of symptoms. Moreover, the diagnosis of FA may be problematic, given that nonallergic food reactions, su...

Guidelines for the diagnosis and management of food allergy in the United States: report of the NIAID-sponsored expert panel

Dec 15th, 2010 - Food allergy is an important public health problem that affects children and adults and may be increasing in prevalence. Despite the risk of severe allergic reactions and even death, there is no current treatment for food allergy: the disease can only be managed by allergen avoidance or treatment of symptoms. The diagnosis and management of food allergy also may vary from one clinical practice ...

Guidelines of care for the management of atopic dermatitis: section 3. Management and t...
Journal of the American Academy of Dermatology; Sidbury R, Davis DM et. al.

May 12th, 2014 - Atopic dermatitis is a chronic, pruritic inflammatory dermatosis that affects up to 25% of children and 2% to 3% of adults. This guideline addresses important clinical questions that arise in atopic dermatitis management and care, providing recommendations based on the available evidence. In this third of 4 sections, treatment of atopic dermatitis with phototherapy and systemic immunomodulators...

Guidelines for the Diagnosis and Management of Asthma

Aug 27th, 2007 - The EPR 3 Guidelines on Asthma was developed by an expert panel commissioned by the National Asthma Education and Prevention Program (NAEPP) Coordinating Committee (CC), coordinated by the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health. Using the 1997 EPR 2 guidelines and the 2004 update of EPR 2 as the framework, the expert panel organized the literature.

Guideline for Preventing Sensitivity and Allergic Reactions to Natural Rubber Latex in the W...
The Society of Gastroenterology Nurses and Associates

Dec 31st, 2006 - Workers and patients exposed to latex gloves and other products containing natural rubber latex may develop sensitivity or allergic reactions such as skin rashes, hives, nasal, eye, or sinus symptoms, asthma, and (rarely) shock. Latex allergy is an increasing problem in health care.

Pharmacologic Treatment of Seasonal Allergic Rhinitis: Synopsis of Guidance From the 20...
Annals of Internal Medicine; Wallace DV, Dykewicz MS et. al.

Nov 28th, 2017 - The Joint Task Force on Practice Parameters, which comprises representatives of the American Academy of Allergy, Asthma and Immunology (AAAAI) and the American College of Allergy, Asthma and Immunology (ACAAI), formed a workgroup to review evidence and provide guidance to health care providers on the initial pharmacologic treatment of seasonal allergic rhinitis in patients aged 12 years or olde...

An Official American Thoracic Society/European Society of Intensive Care Medicine/Socie...
American Journal of Respiratory and Critical Care Medicine; Fan E, Del Sorbo L et. al.

May 1st, 2017 - This document provides evidence-based clinical practice guidelines on the use of mechanical ventilation in adult patients with acute respiratory distress syndrome (ARDS). A multidisciplinary panel conducted systematic reviews and metaanalyses of the relevant research and applied Grading of Recommendations, Assessment, Development, and Evaluation methodology for clinical recommendations. For all...

Epinephrine for First-aid Management of Anaphylaxis.
Pediatrics Sicherer SH, Simons FER et. al.

Feb 14th, 2017 - Anaphylaxis is a severe, generalized allergic or hypersensitivity reaction that is rapid in onset and may cause death. Epinephrine (adrenaline) can be life-saving when administered as rapidly as possible once anaphylaxis is recognized. This clinical report from the American Academy of Pediatrics is an update of the 2007 clinical report on this topic. It provides information to help clinicians i...

International consensus guidelines for the diagnosis and management of food protein-ind...
The Journal of Allergy and Clinical Immunology; Nowak-Węgrzyn A, Chehade M et. al.

Feb 8th, 2017 - Food protein-induced enterocolitis (FPIES) is a non-IgE cell- mediated food allergy that can be severe and lead to shock. Despite the potential seriousness of reactions, awareness of FPIES is low; high-quality studies providing insight into the pathophysiology, diagnosis, and management are lacking; and clinical outcomes are poorly established. This consensus document is the result of work done...

Management of Children With Chronic Wet Cough and Protracted Bacterial Bronchitis: CHES...
Chest Chang AB, Oppenheimer JJ et. al.

Feb 1st, 2017 - Wet or productive cough is common in children with chronic cough. We formulated recommendations based on systematic reviews related to the management of chronic wet cough in children (aged ≤ 14 years) based on two key questions: (1) how effective are antibiotics in improving the resolution of cough? If so, what antibiotic should be used and for how long? and (2) when should children be referred...

Clinical Practice Guidelines for the Management of Atopic Dermatitis 2016.
The Journal of Dermatology; Saeki H, Nakahara T et. al.

Apr 14th, 2016 - Atopic dermatitis (AD) is a disease characterized by relapsing eczema with pruritus as a primary lesion. Most patients have an atopic predisposition. The definitive diagnosis of AD requires the presence of all three features: (i) pruritus; (ii) typical morphology and distribution of the eczema; and (iii) chronic and chronically relapsing course. The current strategies to treat AD in Japan from ...

ETFAD/EADV Eczema task force 2015 position paper on diagnosis and treatment of atopic d...
Journal of the European Academy of Dermatology and Venereology : JEADV; Wollenberg A, Oranje A et. al.

Mar 23rd, 2016 - Atopic dermatitis (AD) is a clinically defined, highly pruritic, chronic inflammatory skin disease of children and adults. The diagnosis is made using evaluated clinical criteria. Disease activity is best measured with a composite score assessing both objective signs and subjective symptoms, such as SCORAD. The management of AD must consider the clinical and pathogenic variabilities of the dise...


Risankizumab (ABBV-066) is an anti-IL-23 antibody being investigated for the treatment of multiple inflammatory diseases, including psoriasis, Crohn's disease, ulcerative colitis, atopic dermatitis and psoriatic arthritis.

CINRYZE® (C1 esterase inhibitor [human])

CINRYZE® (C1 esterase inhibitor [human]) is indicated for routine prophylaxis against angioedema attacks in adults, adolescents and pediatric patients (6 years of age and older) with Hereditary Angioedema (HAE).