×
About 1,845 results

ALLMedicine™ Brugada Syndrome Center

Research & Reviews  682 results

Does function trump bioinformatics in Brugada syndrome-associated SCN5A mutation callin...
https://doi.org/10.1093/eurheartj/ehab292
European Heart Journal; Wilde AAM, Wu CI

Aug 2nd, 2021 - Does function trump bioinformatics in Brugada syndrome-associated SCN5A mutation calling? Patients, computers, and patches.|2021|Wilde AAM,Wu CI,|

Common variants in SCN10A gene associated with Brugada syndrome.
https://doi.org/10.1093/hmg/ddab217
Human Molecular Genetics; Huang Y, Chen XM et. al.

Jul 28th, 2021 - Genome-wide association studies indicate that SCN10A plays an important role in cardiac electrophysiology. Common and rare SCN10A variants are suggested to contribute to Brugada Syndrome (BrS), an inherited channelopathy resulting from genetic-det...

Cardiac surgery and Brugada syndrome: operative considerations.
https://doi.org/10.1093/icvts/ivab199
Interactive Cardiovascular and Thoracic Surgery; Singh S, Chokkarapu SP et. al.

Jul 28th, 2021 - Brugada syndrome is an uncommon arrhythmic disease due to abnormality in myocardial transmembrane sodium channels and is associated with sudden death due to ventricular arrhythmias. We report our strategy and highlight precautions to reduce the ri...

Identification of a SCN5A Founder Mutation Causing Sudden Death, Brugada Syndrome and C...
https://doi.org/10.1016/j.hrthm.2021.07.003
Heart Rhythm; Curcio A, Malovini A et. al.

Jul 11th, 2021 - The genetic architecture of Brugada syndrome (BrS) is emerging as an increasingly complex area of investigation. The identification of genetically homogeneous populations can provide mechanistic insights and improve genotype-phenotype correlation....

Brugada Pattern Manifesting During Hyperkalemia, Diabetic Ketoacidosis, and Acute Alcoh...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8279077
The American Journal of Case Reports; Pfirman KS, Donley CJ et. al.

Jul 9th, 2021 - BACKGROUND Brugada syndrome is a rare ion channelopathy that can lead to sudden cardiac death and lethal arrhythmias in patients without a structural cardiac defect, the most common of which being the gain-of-function mutation of the SCN5a sodium ...

see more →

Drugs  3 results see all →

Clinicaltrials.gov  5 results

Epicardial Ablation in Brugada Syndrome to Prevent Sudden Death
https://clinicaltrials.gov/ct2/show/NCT03294278

Mar 26th, 2020 - The main purpose of this trial is to develop evidence-based curative treatment with optimal net benefit for patients with Brugada syndrome. As recent non-randomized pilot studies and scarce case reports documented the potential benefit of epicardi...

Diagnostic Value and Safety of Flecainide Infusion Test in Brugada Syndrome
https://clinicaltrials.gov/ct2/show/NCT02302274

Oct 25th, 2018 - Brugada Syndrome is an inherited arrhythmogenic disease responsible for life-threatening arrhythmias and sudden cardiac death in young individuals with structural normal heart. It is characterized by a peculiar ECG pattern, but this pattern could ...

Sodium Channel Splicing in Obstructive Sleep Apnea (SOCS-OSA)
https://clinicaltrials.gov/ct2/show/NCT02725632

Apr 26th, 2017 - BACKGROUND & SIGNIFICANCE Obstructive sleep apnea (OSA) is a common disease with an estimated prevalence of 3% to 7%. It is characterized by recurrent episodes of partial or complete collapse of the upper airway during sleep, resulting in hypopnea...

Ajmaline Utilization in the Diagnosis and Treatment of Cardiac Arrhythmias
https://clinicaltrials.gov/ct2/show/NCT00702117

Dec 15th, 2010 - The study evaluates 3 different populations: It is an open, randomized, parallel-group study comparing the effectiveness of intravenous (iv) ajmaline with currently used antiarrhythmic drugs in the acute treatment of : recent-onset atrial fibrilla...

Molecular Genetic Screening and Identification of Congenital Arrhythmogenic Diseases
https://clinicaltrials.gov/ct2/show/NCT00221832

Molecular genetic screening in patients with: supraventricular ventricular arrhythmia syncopes of unknown origin and/or suspicion of an arrhythmogenic origin family members of patients with sudden cardiac death and aborted sudden cardiac death Exa...

see more →

News  45 results

Lamictal (lamotrigine): Drug Safety Communication - Studies Show Increased Risk of Heart Rhythm Problems in Patients with Heart Disease | FDA
https://www.fda.gov/safety/medical-product-safety-information/lamictal-lamotrigine-drug-safety-communication-studies-show-increased-risk-heart-rhythm-problems

[Posted 03/31/2021]  AUDIENCE: Patient, Health Professional, Pharmacy, Neurology, Cardiology, Psychiatry  ISSUE: An FDA review of study findings showed a potential increased risk of heart rhythm problems, called arrhythmias, in patients with heart...

New Model Quantifies Cardiac Arrest Risk in Brugada Syndrome
https://www.medscape.com/viewarticle/940327

Nov 4th, 2020 - NEW YORK (Reuters Health) - A new risk stratification model for patients with Brugada syndrome (BrS) is based on four risk factors for ventricular arrhythmias/sudden cardiac death (VA/SCD) and can inform the need for an implantable cardioverter de...

New Model Quantifies Cardiac Arrest Risk in Brugada Syndrome
https://www.staging.medscape.com/viewarticle/940327

Nov 4th, 2020 - NEW YORK (Reuters Health) - A new risk stratification model for patients with Brugada syndrome (BrS) is based on four risk factors for ventricular arrhythmias/sudden cardiac death (VA/SCD) and can inform the need for an implantable cardioverter de...

Brugada Genes Debunked; T2D Drug Excuses; Paradise Pivotal Trial
https://www.medpagetoday.com/cardiology/prevention/73911

Jul 9th, 2018 - A study reevaluating genes reported to be associated with Brugada syndrome challenged the validity of all but one. (Circulation) The American College of Cardiology renamed its ACTION Registry under the National Cardiovascular Data Registry umbrell...

Robotic Telestenting; BP Cuff Smartwatch; Medicare Bundled Care
https://www.medpagetoday.com/cardiology/prevention/70514

Jan 15th, 2018 - Lipoprotein(a) isn't often tested for or well understood by most clinicians, but can have a big risk for premature heart disease in people who otherwise seem healthy. (New York Times) One lot of clopidogrel (Plavix) tablets from International Labo...

see more →

Patient Education  3 results see all →