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About 1,005 results

ALLMedicine™ Torsade De Pointes Center

Research & Reviews  250 results

Long QT Syndrome and Torsade de Pointes Ultimately Treated With Quinidine: Introducing ...
https://doi.org/10.1161/CIRCULATIONAHA.121.054991
Circulation Viskin S, Marai I et. al.

Jul 6th, 2021 - Long QT Syndrome and Torsade de Pointes Ultimately Treated With Quinidine: Introducing the Concept of Pseudo-Torsade de Pointes.|2021|Viskin S,Marai I,Rosso R,|

The CredibleMeds® list: Usage of QT interval prolonging drugs in Germany and discordanc...
https://doi.org/10.1111/bcp.14951
British Journal of Clinical Pharmacology; Then MI, Andrikyan W et. al.

Jun 22nd, 2021 - A substantial number of Summaries of Product Characteristics (SmPCs)/Prescribing Information (PI) have warnings or contraindications on QT interval prolongation. The goal of this work was to quantify usage of QT interval prolonging drugs according...

Comprehensive Cardiotoxicity Assessment of COVID-19 Treatments Using Human Induced Plur...
https://doi.org/10.1093/toxsci/kfab079
Toxicological Sciences : an Official Journal of the Socie... Yanagida S, Satsuka A et. al.

Jun 18th, 2021 - Coronavirus disease 2019 (COVID-19) continues to spread across the globe, with numerous clinical trials underway seeking to develop and test effective COVID-19 therapies, including remdesivir. Several ongoing studies have reported hydroxychloroqui...

Modulating the voltage sensor of a cardiac potassium channel shows antiarrhythmic effects.
https://doi.org/10.1073/pnas.2024215118
Proceedings of the National Academy of Sciences of the Un... Lin Y, Grinter SZ et. al.

May 15th, 2021 - Cardiac arrhythmias are the most common cause of sudden cardiac death worldwide. Lengthening the ventricular action potential duration (APD), either congenitally or via pathologic or pharmacologic means, predisposes to a life-threatening ventricul...

Cardiovascular Safety of Hydroxychloroquine in Veterans with Rheumatoid Arthritis.
https://doi.org/10.1002/art.41803
Arthritis & Rheumatology (Hoboken, N.J.); Faselis C, Zeng-Treitler Q et. al.

May 11th, 2021 - Hydroxychloroquine (HCQ) may prolong the QT interval, a risk factor for torsade de pointes, a potentially fatal ventricular arrhythmia. We examined the cardiovascular safety of HCQ in patients with rheumatoid arthritis (RA). We conducted an active...

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Guidelines  2 results

Guidelines for reporting case studies and series on drug-induced QT interval prolongati...
https://doi.org/10.1080/15563650.2019.1605077
Clinical Toxicology (Philadelphia, Pa.); Berling I, Hatten BW et. al.

Apr 25th, 2019 - Background: The assessment and management of patients with QT interval prolongation in poisoning requires an appropriate method of measuring and adjusting the QT interval for the heart rate (HR) in order to decide if the patient is at risk of life...

Prevention of torsade de pointes in hospital settings: a scientific statement from the ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3056123
Circulation Drew BJ, Ackerman MJ et. al.

Feb 9th, 2010 - Prevention of torsade de pointes in hospital settings: a scientific statement from the American Heart Association and the American College of Cardiology Foundation.|2010|Drew BJ,Ackerman MJ,Funk M,Gibler WB,Kligfield P,|physiology,epidemiology,phy...

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Drugs  120 results see all →

Clinicaltrials.gov  5 results

A Registry to Determine the Clinical and Genetic Risk Factors for Torsade De Pointes
https://clinicaltrials.gov/ct2/show/NCT02439645

Aug 27th, 2018 - BACKGROUND AND SIGNIFICANCE Drug-induced long QT syndrome (LQTS), and the subsequent fatal arrhythmia torsade de pointes (TdP), is an important side effect associated with the use of a number of medications. Prolongation of the QT interval is the ...

Genetics of QT Prolongation With Antiarrhythmics
https://clinicaltrials.gov/ct2/show/NCT02439658

Aug 27th, 2018 - Drug-induced long QT syndrome (LQTS), and the subsequent fatal arrhythmia torsade de pointes (TdP), is a major concern with use of a number of medications. Prolongation of the QT interval is the most common cause of withdrawal of medications alrea...

KCNH2 Polymorphisms on the QTc Interval in Kelantanese Malays Patients Receiving Methadone Maintenance Therapy (MMT)
https://clinicaltrials.gov/ct2/show/NCT03603158

Jul 29th, 2018 - Methadone maintenance therapy (MMT) is one of the modalities to prevent HIV transmission among injected drug users, particularly in opioid-dependent users. However, methadone-associated cardiotoxicity is one of the fatal adverse events that limit ...

Risk of QT-prolongation and Torsade de Pointes in Patients Treated With Acute Medication in a University Hospital
https://clinicaltrials.gov/ct2/show/NCT02068170

Jul 27th, 2015 - A prospective, observational study in a university hospital (UZ Leuven). Patients are included when they are treated with a potentional QT-prolonging drug: haloperidol for delirium, antibiotics (moxifloxacin, levofloxacin, azithromycin, clarithrom...

Comparison of Two Macrolides, Azithromycin and Erythromycin, for Symptomatic Treatment of Gastroparesis
https://clinicaltrials.gov/ct2/show/NCT01323582

Dec 4th, 2014 - Gastroparesis (GP) is a chronic gastrointestinal motility disorder resulting from delayed transit of gastric contents from the stomach into the duodenum in the absence of mechanical outlet obstruction. The symptoms of GP are variable but include e...

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News  25 results

Cardiology Groups Push Back on Hydroxychloroquine, Azithromycin for COVID-19
https://www.staging.medscape.com/viewarticle/928456

Apr 8th, 2020 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. The nation's leading cardiology associations urged caution with hydroxychloroquine and azithromycin for COVID-19 in patients with cardiovascular d...

ECG Challenge: Teen With His First Seizure
https://www.medscape.com/viewarticle/920545_2

Nov 5th, 2019 - The correct diagnosis is long QT, torsade de pointes (Figure 2). Figure 2. Courtesy of Dr Podrid. Discussion The first QRS complex is narrow and supraventricular (*). It is followed by a rapid and irregular rhythm with a rate of up to 300 beats/mi...

A 10-Year-Old Boy With Fainting Spells and Seizure Activity
https://reference.medscape.com/viewarticle/884107_6

Sep 24th, 2019 - Question 1 of 2 Which of the following conditions is not associated with congenital LQTS? Your Peers Chose: Congenital sensorineural hearing loss 0% Congenital optic atrophy 0% Syncopal attacks 0% Seizures 0% Sudden cardiac death 0% Important clue...

Is Prucalopride the Gastroparesis Treatment We've Been Waiting For?
https://www.medscape.com/viewarticle/916387

Aug 19th, 2019 - This transcript has been edited for clarity. Hello. I'm Dr David Johnson, professor of medicine and chief of gastroenterology at Eastern Virginia Medical School in Norfolk, Virginia. If you've been taking care of patients in a practice, you'll rec...

Is Prucalopride the Gastroparesis Treatment We've Been Waiting For?
https://www.staging.medscape.com/viewarticle/916387

Aug 19th, 2019 - This transcript has been edited for clarity. Hello. I'm Dr David Johnson, professor of medicine and chief of gastroenterology at Eastern Virginia Medical School in Norfolk, Virginia. If you've been taking care of patients in a practice, you'll rec...

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