ALLMedicine™ Torsade De Pointes Center
Research & Reviews 643 results
https://doi.org/10.1097/PRA.0000000000000526
Journal of Psychiatric Practice; Preskorn SH, Lochmann DB et. al.
Jan 13th, 2021 - QTc stands for heart-rate corrected QT interval on the electrocardiogram and is a measure of the efficiency of repolarization of the left ventricle. Excessive prolongation, generally considered to be >500 ms, can result in a potentially fatal vent...
https://doi.org/10.1002/cpt.2137
Clinical Pharmacology and Therapeutics; Strauss DG, Wu WW et. al.
Dec 17th, 2020 - After multiple drugs were removed from the market secondary to drug-induced torsade de pointes (TdP) risk, the International Council for Harmonisation (ICH) released guidelines in 2005 that focused on the nonclinical (S7B) and clinical (E14) asses...
https://doi.org/10.1002/cpt.2133
Clinical Pharmacology and Therapeutics; Liu T, Liu J et. al.
Dec 7th, 2020 - Drugs that prolong QT may cause torsade de pointes (TdP). However, translation of nonclinical assessment of QT prolongation or hERG channel, targeted by QT-prolonging drugs, into clinical TdP risk has been insufficient to date. In this blinded stu...
https://doi.org/10.1007/s00228-020-03049-x
European Journal of Clinical Pharmacology; Elsayed M, Abdel-Kahaar E et. al.
Nov 24th, 2020 - Most psychiatric drugs, such as antidepressants (AD) and antipsychotics (AP), may cause cardiac adverse events (CAE). We used summaries of product characteristics (SmPC) for assessing the likelihood of AD and AP to cause CAE. We identified all ori...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738207
Expert Review of Pharmacoeconomics & Outcomes Research; Diaby V, Almutairi RD et. al.
Nov 13th, 2020 - Background: Hydroxychloroquine, an antimalarial drug, combined with azithromycin has been considered a potential treatment for COVID-19. However, these drugs may cause electrocardiogram QT prolongation (QTp) and torsade de Pointes (TdP). We examin...
Guidelines 2 results
https://doi.org/10.1080/15563650.2019.1605077
Clinical Toxicology (Philadelphia, Pa.); Berling I, Hatten BW et. al.
Apr 25th, 2019 - Background: The assessment and management of patients with QT interval prolongation in poisoning requires an appropriate method of measuring and adjusting the QT interval for the heart rate (HR) in order to decide if the patient is at risk of life...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3056123
Circulation Drew BJ, Ackerman MJ et. al.
Feb 9th, 2010 - Prevention of torsade de pointes in hospital settings: a scientific statement from the American Heart Association and the American College of Cardiology Foundation.|2010|Drew BJ,Ackerman MJ,Funk M,Gibler WB,Kligfield P,|physiology,epidemiology,phy...
Drugs 69 results see all →
Clinicaltrials.gov 755 results
https://doi.org/10.1097/PRA.0000000000000526
Journal of Psychiatric Practice; Preskorn SH, Lochmann DB et. al.
Jan 13th, 2021 - QTc stands for heart-rate corrected QT interval on the electrocardiogram and is a measure of the efficiency of repolarization of the left ventricle. Excessive prolongation, generally considered to be >500 ms, can result in a potentially fatal vent...
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=80c13492-3873-48ba-882f-58e02dc7237d
Dec 31st, 2020 - Ziprasidone hydrochloride capsules are indicated for the treatment of schizophrenia. When deciding among the alternative treatments available for the condition needing treatment, the prescriber should consider the finding of ziprasidone’ s greater...
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b650e8b6-6df7-4301-837d-3d3b650b7456
Dec 31st, 2020 - Ziprasidone hydrochloride capsules are indicated for the treatment of schizophrenia. When deciding among the alternative treatments available for the condition needing treatment, the prescriber should consider the finding of ziprasidone's greater ...
https://doi.org/10.1002/cpt.2137
Clinical Pharmacology and Therapeutics; Strauss DG, Wu WW et. al.
Dec 17th, 2020 - After multiple drugs were removed from the market secondary to drug-induced torsade de pointes (TdP) risk, the International Council for Harmonisation (ICH) released guidelines in 2005 that focused on the nonclinical (S7B) and clinical (E14) asses...
https://doi.org/10.1002/cpt.2133
Clinical Pharmacology and Therapeutics; Liu T, Liu J et. al.
Dec 7th, 2020 - Drugs that prolong QT may cause torsade de pointes (TdP). However, translation of nonclinical assessment of QT prolongation or hERG channel, targeted by QT-prolonging drugs, into clinical TdP risk has been insufficient to date. In this blinded stu...
News 31 results
https://www.staging.medscape.com/viewarticle/928456
Apr 8th, 2020 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. The nation's leading cardiology associations urged caution with hydroxychloroquine and azithromycin for COVID-19 in patients with cardiovascular d...
https://www.medscape.com/viewarticle/928456
Apr 8th, 2020 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. The nation's leading cardiology associations urged caution with hydroxychloroquine and azithromycin for COVID-19 in patients with cardiovascular d...
https://www.medscape.com/viewarticle/920545_2
Nov 5th, 2019 - The correct diagnosis is long QT, torsade de pointes (Figure 2). Figure 2. Courtesy of Dr Podrid. Discussion The first QRS complex is narrow and supraventricular (*). It is followed by a rapid and irregular rhythm with a rate of up to 300 beats/mi...
https://www.medpagetoday.com/cardiology/prevention/81440
Aug 6th, 2019 - Certain Ellipse implantable cardioverter defibrillators from Abbott are under Class I recall because of electrical failures attributed to a faulty manufacturing process, the FDA announced. Thanks to artificial intelligence, the VMS+ system may all...
https://www.medpagetoday.com/cardiology/arrhythmias/74350
Aug 1st, 2018 - Action Points Healthy women on oral contraceptives may have a higher risk for drug-induced alterations of ventricular repolarization. Note that the results generate the hypothesis that drospirenone may be a risk factor for drug-induced torsade de ...