ALLMedicine™ Torsade De Pointes Center

Oct 8th, 2020 - Torsade de Pointes arrhythmia is a potentially lethal polymorphic ventricular tachyarrhythmia (pVT) in the setting of long QT syndrome. Arrhythmia susceptibility is influenced by risk factors modifying repolarization. To characterize repolarizatio...

Oct 7th, 2020 - Bepridil prolongs the QT interval and can induce torsade de pointes. Although increased bepridil concentration may be a primary cause of prolonged QT, the relationship between serum bepridil concentration and prolonged QT remains unclear. We inves...

Oct 2nd, 2020 - Background - The SARs-CoV-2 coronavirus has resulted in a global pandemic. Hydroxychloroquine ± azithromycin have been widely used to treat COVID-19 despite a paucity of evidence regarding efficacy. The incidence of torsade de pointes (TdP) remain...

Sep 14th, 2020 - Ivabradine is a selective inhibitor of the sinoatrial node "funny" current, prolonging the slow diastolic depolarization. As it has the ability to block the heart rate selectively, it is more effective at a faster heart rate. It is recommended for...

Aug 9th, 2020 - It has been two decades since screening new molecules and potential clinical drug candidates against the hERG potassium channel became a routine part of safety pharmacology. The earliest heuristic for what was an adequate safety margin to separate...

Apr 25th, 2019 - Background: The assessment and management of patients with QT interval prolongation in poisoning requires an appropriate method of measuring and adjusting the QT interval for the heart rate (HR) in order to decide if the patient is at risk of life...

Feb 9th, 2010 - Prevention of torsade de pointes in hospital settings: a scientific statement from the American Heart Association and the American College of Cardiology Foundation.|2010|Drew BJ,Ackerman MJ,Funk M,Gibler WB,Kligfield P,|physiology,epidemiology,phy...

Oct 8th, 2020 - Torsade de Pointes arrhythmia is a potentially lethal polymorphic ventricular tachyarrhythmia (pVT) in the setting of long QT syndrome. Arrhythmia susceptibility is influenced by risk factors modifying repolarization. To characterize repolarizatio...

Oct 7th, 2020 - Bepridil prolongs the QT interval and can induce torsade de pointes. Although increased bepridil concentration may be a primary cause of prolonged QT, the relationship between serum bepridil concentration and prolonged QT remains unclear. We inves...

Oct 2nd, 2020 - Background - The SARs-CoV-2 coronavirus has resulted in a global pandemic. Hydroxychloroquine ± azithromycin have been widely used to treat COVID-19 despite a paucity of evidence regarding efficacy. The incidence of torsade de pointes (TdP) remain...

Sep 14th, 2020 - Ivabradine is a selective inhibitor of the sinoatrial node "funny" current, prolonging the slow diastolic depolarization. As it has the ability to block the heart rate selectively, it is more effective at a faster heart rate. It is recommended for...

Sep 6th, 2020 - Ziprasidone mesylate for injection intramuscular is indicated for acute agitation in schizophrenic patients. When deciding among the alternative treatments available for the condition needing treatment, the prescriber should consider the finding o...

Aug 6th, 2019 - Certain Ellipse implantable cardioverter defibrillators from Abbott are under Class I recall because of electrical failures attributed to a faulty manufacturing process, the FDA announced. Thanks to artificial intelligence, the VMS+ system may all...

Aug 1st, 2018 - Action Points Healthy women on oral contraceptives may have a higher risk for drug-induced alterations of ventricular repolarization. Note that the results generate the hypothesis that drospirenone may be a risk factor for drug-induced torsade de ...

Sep 15th, 2011 - WASHINGTON -- A drug used to treat nausea and vomiting caused by chemotherapy may trigger dangerous and possibly lethal changes in heart rhythms, the FDA warned Thursday. The drug, ondansetron (Zofran), may increase the risk of "developing prolong...

Feb 8th, 2010 - Action Points Note that an awareness of drug-induced torsade de pointes and a protocol for treating it could save lives in the hospital when the rare condition strikes, according to a statement by three professional associations. Note that the sta...