ALLMedicine™ Long QT Syndrome Center

Oct 4th, 2022 - Clustered regularly interspaced short palindromic repeats (CRISPR) in animal models enable precise genetic manipulation for the study of physiological phenomena. Zebrafish have been used as an effective genetic model to study numerous questions re...

Sep 30th, 2022 - There are no recommended guidelines or clinical studies on safety of COVID-19 vaccines in patients with inborn errors of metabolism (IEMs). Here, we aimed to examine the relationship between COVID-19 vaccination and metabolic outcome in paediatric...

Sep 28th, 2022 - There have been remarkable advances in our knowledge of the underlying heritability of cardiac arrhythmias. Long QT syndrome, Brugada syndrome, catecholaminergic polymorphic ventricular tachycardia, progressive cardiac conduction disease and the s...

Sep 24th, 2022 - The subcutaneous implantable cardioverter defibrillator (S-ICD) was developed as an alternative to the transvenous ICD, to prevent lead-related complications associated with the latter. The absence of intravascular or intracardiac components offer...

Sep 23rd, 2022 - Inherited primary arrhythmia syndromes and arrhythmogenic cardiomyopathies can lead to sudden cardiac arrest in otherwise healthy individuals. The burden and expression of these diseases in a real-world, well-phenotyped cardiovascular population i...

Sep 2nd, 2022 - There is a deficit in literature assessing the risk associated with these repurposed medications in COVID-19 patients. The investigators propose to evaluate if the use of repurposed drugs including hydroxychloroquine and chloroquine is associated ...

Aug 24th, 2022 - This study will address the hypothesis that re-phenotyping patients with AF and pathogenic arrhythmia/CM variants will identify unrecognized underlying genetic disease. The investigators will recruit from participants sequenced as part of our pros...

Aug 17th, 2022 - It is estimated that approximately 600 apparently fit and healthy individuals aged under 35 years die suddenly in the UK every year Many of these sudden cardiac deaths (SCD) in the young are the result of inherited cardiac conditions (ICC), the ma...

Jun 14th, 2022 - Pressure wire-based Fractional Flow Reserve (FFR) has become the reference standard index of haemodynamic significance to guide revascularisation of intermediate coronary artery lesions. The FFR measurement determines the ratio of the maximum bloo...

Apr 27th, 2022 - The study will involve acquiring ECG data in a cohort of up to 1,000 newborns and infants (500 controls (non-LQTS) and 500 LQTS newborns and infants) that are being seen in the Gonda SL ECG Lab (or Baldwin Building)and enrolled during their appoin...

Sep 30th, 2022 - Updated clinical guidelines for managing patients with ventricular arrhythmias and preventing sudden cardiac death were published in August 2022 by the European Society of Cardiology (ESC), in the European Heart Journal.[1] In patients presenting ...

Apr 12th, 2022 - Physicians doing a diagnostic workup for nocturnal enuresis, or bedwetting, appear to rarely consider cardiac arrhythmia as a differential diagnosis, new research suggests. Researchers surveyed doctors about how they would approach assessment of a...

Jan 4th, 2022 - A new analysis of cardiovascular adverse drug reactions for non–small cell lung cancer (NCSLC)–targeted therapies finds that ALK and ROS1 inhibitors are associated with higher odds of conduction disease and QT prolongation than BRAF and EGFR inhib.

Aug 19th, 2021 - (Reuters Health) - Women with long QT syndrome who use progestin-only oral contraceptives without concomitant beta-blockers are at increased risk for cardiac events, a new study suggests. Researchers examined data on 1,659 women with long QT syndr...

Aug 17th, 2021 - The story of interventional cardiologist Sherman Sorensen, MD, and his numerous patent foramen ovale closures, fraudulent billing, and pending malpractice lawsuits. (The Atlantic) A cardiologist in Australia caught with "deviant, distressing and d...