About 1,265 results

ALLMedicine™ Torsade De Pointes Center

Research & Reviews  313 results

Prolonged QT Interval in Cirrhosis: Twisting Time?
Gut and Liver; Lee W, Vandenberk B et. al.

Jul 23rd, 2022 - Approximately 30% to 70% of patients with cirrhosis have QT interval prolongation. In patients without cirrhosis, QT prolongation is associated with an increased risk of ventricular arrhythmias, such as torsade de pointes (TdP). In cirrhotic patie...

Hypomagnesemia Clinical Presentation

Jul 19th, 2022 - History At least 10 inherited disorders of magnesium handling cause hypomagnesemia. [117] Consequently, a careful family history is important, particularly when acquired causes of hypomagnesemia have been excluded. Magnesium is critically importan...

Atrioventricular Block Clinical Presentation

Jul 13th, 2022 - History The degree atrioventricular (AV) block is generally associated with the severity of symptoms and clinical history. Common presentations and symptoms are outlined below for the different types of AV block. Any level of AV block leading to p...

Torsade de Pointes/QT Prolongation Associated with Antifungal Triazoles: A Pharmacovigi...
Journal of Pharmacy & Pharmaceutical Sciences : a Publica... Yu Z, Liao X

Jul 6th, 2022 - Torsade de pointes (TdP)/QT prolongation is a fatal adverse event (AE) when using antifungal triazoles. We aimed to compare the AE signals of TdP/QT prolongation and onset time among different drugs of this kind comprehensively. This retrospective...

Hypermagnesemia in Emergency Medicine

Jun 23rd, 2022 - Practice Essentials Magnesium is one of the body's major electrolytes. As the second most common intracellular cation, it plays a vital role in many cellular metabolic pathways. [1] Magnesium is required for deoxyribonucleic acid (DNA) and protein...

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Guidelines  2 results

Guidelines for reporting case studies and series on drug-induced QT interval prolongati...
Clinical Toxicology (Philadelphia, Pa.); Berling I, Hatten BW et. al.

Apr 26th, 2019 - Background: The assessment and management of patients with QT interval prolongation in poisoning requires an appropriate method of measuring and adjusting the QT interval for the heart rate (HR) in order to decide if the patient is at risk of life...

Prevention of torsade de pointes in hospital settings: a scientific statement from the ...
Circulation Drew BJ, Ackerman MJ et. al.

Feb 10th, 2010 - Prevention of torsade de pointes in hospital settings: a scientific statement from the American Heart Association and the American College of Cardiology Foundation.|2010|Drew BJ,Ackerman MJ,Funk M,Gibler WB,Kligfield P,|physiology,epidemiology,phy...

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Drugs  144 results see all →

Clinicaltrials.gov  13 results

Long-term Efficacy Study of Sodium Channel Blocker in LQT3 Patients

Apr 7th, 2022 - Long QT syndrome (LQTS) is a genetic disorder characterized by prolongation of the QT interval in the electrocardiogram (ECG) and a propensity to torsade de pointes ventricular tachycardia frequently leading to syncope, cardiac arrest, or sudden d...

Thorough QT/QTc Study of Multiple Oral Doses of NOMAC-E2 (Org 10486 0 + Org 2317) in Healthy Women (Study 292011)(P05802)

Feb 16th, 2022 - The trial is a single-center randomized, double-blind, double-dummy, placebo and positive controlled, parallel group clinical trial. This trial investigated whether NOMAC-E2 (Org 10486 -0 + Org 2317), a new combined hormonal contraceptive, has pot...

Genetics of QT Response to Moxifloxacin

Jan 12th, 2022 - I. Background and Significance A. Historical Background and Scientific Basis The most common cause of withdrawal or restriction of drugs that are already on the market is prolongation of the QT interval, and the consequent, potentially fatal, arrh...

A Registry to Determine the Clinical and Genetic Risk Factors for Torsade De Pointes

Dec 3rd, 2021 - BACKGROUND AND SIGNIFICANCE Drug-induced long QT syndrome (LQTS), and the subsequent fatal arrhythmia torsade de pointes (TdP), is an important side effect associated with the use of a number of medications. Prolongation of the QT interval is the ...

The Comparison of Changes of QTc, Tp-e Interval, and Tp-e/QT Ratio, Tp-e/QTc Ratio on the ECG During Living Donor Liver Transplantation Under Desflurane and Total Intravenous Anesthesia -Randomized...

Oct 15th, 2021 - Prolonged corrected QT interval (QTc) has been observed in about half of patients with liver cirrhosis. Marked prolongation of QTc (ie, 500 msec) has been considered to be a risk factor for fatal ventricular arrhythmia, such as torsade de pointes,...

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News  33 results

Antibiotics Used in Dialysis Patients Linked With Sudden Cardiac Death

Oct 20th, 2021 - Fluoroquinolones were associated with a modest uptick in sudden cardiac death (SCD) among people getting hemodialysis, though the benefits of these antibiotics may still outweigh their risks in this group, according to a study. SCD rates within 5 ...

Do You Believe in HCQ for COVID-19? It Will Break Your Heart

May 6th, 2020 - Chloroquine and hydroxychloroquine (HCQ) have been touted as promising and effective treatments for patients with COVID-19 infection. The drugs are often recommended to be used together with azithromycin, an antibiotic. On March 21, 2020, Presiden...

Cardiology Groups Push Back on Hydroxychloroquine, Azithromycin for COVID-19

Apr 9th, 2020 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. The nation's leading cardiology associations urged caution with hydroxychloroquine and azithromycin for COVID-19 in patients with cardiovascular d...

Cardiology groups push back on hydroxychloroquine, azithromycin for COVID-19
M. Alexander Otto

Apr 8th, 2020 - The nation’s leading cardiology associations urged caution with hydroxychloroquine and azithromycin for COVID-19 in patients with cardiovascular disease. Thinkstock “Hydroxychloroquine and azithromycin have been touted for potential prophylaxis or.

ECG Challenge: Teen With His First Seizure

Nov 6th, 2019 - The correct diagnosis is long QT, torsade de pointes (Figure 2). Figure 2. Courtesy of Dr Podrid. Discussion The first QRS complex is narrow and supraventricular (*). It is followed by a rapid and irregular rhythm with a rate of up to 300 beats/mi...

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Patient Education  1 results see all →