ALLMedicine™ Atherosclerosis Center

Mar 20th, 2023 - Atherosclerosis (AS) is a chronic inflammatory disease, as a main cause leading to vascular diseases worldwide. Although increasing studies have focused on macrophages in AS, the exact relating mechanism is still largely unclear. Our study aimed t...

Mar 19th, 2023 - This review aims to summarize key articles published in the Journal of Cardiovascular Computed Tomography (JCCT) in 2022, focusing on those that had the most scientific and educational impact. The JCCT continues to expand; the number of submission...

Mar 19th, 2023 - In patients with type 2 diabetes who were inadequately controlled with metformin and sulfonylurea, we compared the glucose-lowering efficacy, cardiometabolic parameters, and safety of two drugs, ipragliflozin, a SGLT-2 inhibitor, and sitagliptin, ...

Mar 18th, 2023 - Background Although there is research on the impact of social determinants of health (SDOHs) on cardiovascular health, most existing evidence is based on individual SDOH components. We evaluated the impact of cumulative SDOH burden on cardiovascul...

Mar 18th, 2023 - Background Childhood exposure to dyslipidemia is associated with adult atherosclerosis, but it is unclear whether the long-term risk associated with dyslipidemia is attenuated on its resolution by adulthood. We aimed to address this question by ex...

Aug 13th, 2022 - Atherosclerosis begins in youth and is directly linked with the presence and severity of cardiovascular risk factors, including dyslipidemia. Thus, the timely identification and management of dyslipidemia in childhood might slow atherosclerotic pr...

May 11th, 2022 - Patients with widespread atherosclerosis such as peripheral artery disease (PAD) have a high risk of cardiovascular and limb symptoms and complications, which affects their quality of life and longevity. Over the past 2 decades there have been sub...

Apr 21st, 2022 - Dunnigan syndrome, or Familial Partial Lipodystrophy type 2 (FPLD2; ORPHA 2348), is a rare autosomal dominant disorder due to pathogenic variants of the LMNA gene. The objective of the French National Diagnosis and Care Protocol (PNDS; Protocole N...

Mar 23rd, 2022 - To review treatments for reducing the risk of recurrent stroke or death in patients with symptomatic intracranial atherosclerotic arterial stenosis (sICAS). The development of this practice advisory followed the process outlined in the American Ac...

May 8th, 2021 - Coronary atherosclerotic disease is a leading cause of mortality and morbidity due to major cardiovascular events in the United States and abroad. Risk stratification and early preventive measures can reduce major cardiovascular events given the l...

Mar 10th, 2023 - Hypercholesterolemia is a risk factor for the occurrence and development of atherosclerosis. Recent animal studies have found that increased serum cholesterol level is associated with peripheral Treg cell senescence, but clinical evidence is still...

Mar 10th, 2023 - Study Description: This is a deep phenotype study of women who are determined to have 45,X mosaicism as a secondary genomic finding following cfDNA sequencing during pregnancy. Objectives: To define and describe a comprehensive phenotype of women ...

Mar 10th, 2023 - According to the latest 2021 data from the International Diabetes Federation, an estimated 537 million adults are living with DM globally.3 Prevalence is increasing rapidly, with numbers projected to rise to 643 million by 2030 and 783 million by ...

Mar 10th, 2023 - The PROVE-DM trial is a multi-center, open-labeled, randomized controlled trial comparing two different lipid lowering strategies in patients with prediabetes and established atherosclerosis. Patients with prediabetes and documented atherosclerosi...

Mar 10th, 2023 - Background: SARS-CoV-2 has affected almost every country worldwide with regard to health system capacities and economic burden, so far. The typical clinical presentations of COVID-19 are fever, sore through, cough, dyspnea, abdominal pain and diar...

Mar 2nd, 2023 - Older adults who added a quarter mile of steps to their day showed a reduction in risk of cardiovascular events by 14% within 4 years, according to a study in more than 400 individuals. “Aging is such a dynamic process, but most studies of daily s.

Feb 21st, 2023 - Irregular sleeping habits were associated with measures of subclinical atherosclerosis, including coronary artery calcium burden and abnormal ankle‐brachial index, in middle age. (Journal of the American Heart Association) Meanwhile, better cardio...

Feb 20th, 2023 - Neurodegenerative pathologies have shown few differences over time despite falling dementia incidence rates, brain autopsy data suggested. In over 1,500 deceased people from birth epochs spanning 25 years (1905-1930), no significant differences in...

Feb 7th, 2023 - Pregnant women should undergo frequent blood pressure checks to identify not just one but all hypertensive disorders of pregnancy, the U.S. Preventive Services Task Force (USPSTF) proposed. In a draft recommendation statement, the USPSTF said that...

Jan 31st, 2023 - Want good Yelp reviews? Positive online reviews of cardiologists tended to focus on patient‐perceived cardiologist competency, thoroughness, and positive staff interactions. (Journal of the American Heart Association) Former Pfizer executive remar...