ALLMedicine™ Coronary Artery Disease Center

Sep 23rd, 2021 - Hypertriglyceridemia has emerged as a critical coronary artery disease (CAD) risk factor. Rare loss-of-function (LoF) variants in apolipoprotein C-III have been reported to reduce triglycerides (TG) and are cardioprotective in American Indians and...

Sep 22nd, 2021 - Coronary artery disease (CAD) has been the leading cause of morbidity and mortality worldwide, and its pathogenesis is closely related with the proliferation and migration of vascular smooth muscle cell (VSMC). We previously reported a truncated G...

Sep 22nd, 2021 - Flecainide is a useful antiarrhythmic for atrial fibrillation (AF). However, because of ventricular proarrhythmia risk, a history of myocardial infarction (MI) or coronary artery disease (CAD) is a flecainide exclusion, and stress testing is used ...

Sep 22nd, 2021 - AZD5718, a 5-lipoxygenase-activating protein (FLAP) inhibitor, is in clinical development for treatment of coronary artery disease (CAD) and chronic kidney disease (CKD). This study evaluated AZD5718 pharmacokinetics, pharmacodynamics, and tolerab...

Sep 21st, 2021 - In this international, multicenter study, using third-generation dual-source computed tomography (CT), we investigated the diagnostic performance of dynamic stress CT myocardial perfusion imaging (CT-MPI) in addition to coronary CT angiography (CT...

May 8th, 2021 - Coronary atherosclerotic disease is a leading cause of mortality and morbidity due to major cardiovascular events in the United States and abroad. Risk stratification and early preventive measures can reduce major cardiovascular events given the l...

Dec 29th, 2020 - Myocardial infarction without obstructive coronary artery disease (MINOCA) is defined by the evidence of spontaneous acute myocardial infarction (MI) and angiographic exclusion of coronary stenoses ≥50% in any potential infarct related artery, aft...

Nov 11th, 2020 - Cardiovascular computed tomography (CCT) is a well-validated non-invasive imaging tool with an ever-expanding array of applications beyond the assessment of coronary artery disease. These include the evaluation of structural heart diseases, congen...

Nov 7th, 2020 - Patients with acute nonspecific chest pain and low probability for coronary disease remain an important clinical management dilemma. We focus on evidence for imaging, in an integrated decision-making setting. The American College of Radiology Appr...

May 7th, 2020 - Chest pain is a frequent cause for emergency department visits and inpatient evaluation, with particular concern for acute coronary syndrome as an etiology, since cardiovascular disease is the leading cause of death in the United States. Although ...

Jun 28th, 2021 - The resuscitation of Danish professional soccer player Christian Eriksen on the pitch, in front of millions of people, is a chance to consider how the United States could do better in the prevention and treatment of sudden cardiac death (SCD).   T...

Jun 28th, 2021 - Headache specialists face many challenges and difficult decisions in the treatment of acute migraine. They must first accurately distinguish acute migraine from migraine mimics such as thunderclap headaches or a COVID-19 headache without fever. Ac...

Jun 22nd, 2021 - Obstructive sleep apnea (OSA) is common in patients with cardiovascular disease (CVD), yet it is often under-recognized and treated in cardiovascular practice, the American Heart Association (AHA) says in a new scientific statement. "Obstructive s...

Jun 17th, 2021 - NEW YORK (Reuters Health) - People with HIV have a rate of sudden cardiac death that is more than double that in the non-infected population, according to a new study of cases in San Francisco County in California. But a closer look at those death...

Jun 17th, 2021 - A 52-year-old man with a history of coronary artery disease and hypertension — treated with an angiotensin-converting enzyme (ACE) inhibitor, a beta-blocker, and long-acting nitrate — visits the emergency department with complaints of lightheadedn...