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About 216,772 results

ALLMedicine Heart Failure Center

Research & Reviews  94,163 results

Gut microbial diversity, inflammation, and oxidative stress are associated with tacroli...
https://doi.org/10.1371/journal.pone.0233646
PloS One; Jennings DL, Bohn B et. al.

May 29th, 2020 - Effective tacrolimus (TAC) dosing is hampered by complex pharmacokinetics and significant patient variability. The gut microbiome, a key mediator of endotoxemia, inflammation and oxidative stress in advanced heart failure (HF) patients, is a possi...

Sacubitril/Valsartan (Entresto®) utilisation and prescribing patterns in the context of...
https://doi.org/10.1111/bcp.14393
British Journal of Clinical Pharmacology; Kennedy C, Smith A et. al.

May 29th, 2020 - Entresto® (sacubitril/valsartan) is used to treat symptomatic chronic heart failure with reduced ejection fraction. Given its high potential budget impact, the Health Services Executive introduced a reimbursement application system (RAS) to ensure...

Risk Scores Did Not Reliably Predict Individual Risk Of Mortality For Patients With Dec...
https://doi.org/10.1016/j.jclinepi.2020.05.020
Journal of Clinical Epidemiology; Scrutinio D, Guida P et. al.

May 28th, 2020 - We investigated the performance of four prognostic tools in predicting 180-day mortality for patients admitted for decompensated heart failure (ADHF) by calculating sensitivity, specificity, positive predictive value (PPV), and negative predictive...

Klotho alleviates indoxyl sulfate-induced heart failure and kidney damage by promoting ...
https://doi.org/10.18632/aging.103183
Aging Lv J, Chen J et. al.

May 28th, 2020 - Indoxyl sulfate (IS) is a protein-bound uremic toxin that can accumulate in patients with chronic kidney disease (CKD) or acute kidney injury (AKI) and cause kidney and cardiac dysfunction. Klotho is an anti-aging protein that has reno- and cardio...

Self-Maintenance of Cardiac Resident Reparative Macrophages Attenuates Doxorubicin-indu...
https://doi.org/10.1161/CIRCRESAHA.119.316428
Circulation Research; Zhang H, Xu A et. al.

May 28th, 2020 - Rationale: Doxorubicin-induced cardiomyopathy (DiCM) is a primary cause of heart failure and mortality in cancer patients, in which macrophage-orchestrated inflammation serves as an essential pathological mechanism. However, the specific roles of ...

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Guidelines  277 results

Meeting News From ACC 2020
https://www.healio.com/cardiology/meeting-news/acc-meeting
Cardiology Today;

Apr 1st, 2020 - The latest news from the ACC Annual Scientific Session, with physician perspective, researcher interviews and clinician insight on cardiovascular prevention, heart failure and more.

Patients taking ACE-i and ARBs who contract COVID-19 should continue treatment, unless otherwise advised by their physician
https://newsroom.heart.org/news/patients-taking-ace-i-and-arbs-who-contract-covid-19-should-continue-treatment-unless-otherwise-advised-by-their-physician
American Heart Association;

Mar 16th, 2020 - As the global impact of COVID-19 rises, the scientific community continues to evaluate the clinical impact and health care needs of patients with cardiovascular disease, who are at increased risk for serious complications with COVID-19. Together, ...

2020 ACC/HFSA/ISHLT Lifelong Learning Statement for Advanced Heart Failure and Transpla...
https://doi.org/10.1016/j.jacc.2019.09.030
Journal of the American College of Cardiology; Yancy CW, Drazner MH et. al.

Feb 22nd, 2020 - 2020 ACC/HFSA/ISHLT Lifelong Learning Statement for Advanced Heart Failure and Transplant Cardiology Specialists: A Report of the ACC Competency Management Committee.|2020|Yancy CW,Drazner MH,Coffin ST,Cornwell W,Desai S,|

2020 ACC/HFSA/ISHLT Lifelong Learning Statement for Advanced Heart Failure and Transpla...
https://doi.org/10.1016/j.cardfail.2020.01.008
Journal of Cardiac Failure; , Yancy CW et. al.

Feb 22nd, 2020 - 2020 ACC/HFSA/ISHLT Lifelong Learning Statement for Advanced Heart Failure and Transplant Cardiology Specialists: A Report of the ACC Competency Management Committee.|2020| ,Yancy CW,Drazner MH,Coffin ST,Cornwell W,|

CCS/CHFS Heart Failure Guidelines: Clinical Trial Update on Functional Mitral Regurgita...
https://doi.org/10.1016/j.cjca.2019.11.036
The Canadian Journal of Cardiology; O'Meara E, McDonald M et. al.

Feb 9th, 2020 - In this update, we focus on selected topics of high clinical relevance for health care providers who treat patients with heart failure (HF), on the basis of clinical trials published after 2017. Our objective was to review the evidence, and provid...

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Drugs  2,373 results see all →

Clinicaltrials.gov  107,053 results

Gut microbial diversity, inflammation, and oxidative stress are associated with tacroli...
https://doi.org/10.1371/journal.pone.0233646
PloS One; Jennings DL, Bohn B et. al.

May 29th, 2020 - Effective tacrolimus (TAC) dosing is hampered by complex pharmacokinetics and significant patient variability. The gut microbiome, a key mediator of endotoxemia, inflammation and oxidative stress in advanced heart failure (HF) patients, is a possi...

Sacubitril/Valsartan (Entresto®) utilisation and prescribing patterns in the context of...
https://doi.org/10.1111/bcp.14393
British Journal of Clinical Pharmacology; Kennedy C, Smith A et. al.

May 29th, 2020 - Entresto® (sacubitril/valsartan) is used to treat symptomatic chronic heart failure with reduced ejection fraction. Given its high potential budget impact, the Health Services Executive introduced a reimbursement application system (RAS) to ensure...

Risk Scores Did Not Reliably Predict Individual Risk Of Mortality For Patients With Dec...
https://doi.org/10.1016/j.jclinepi.2020.05.020
Journal of Clinical Epidemiology; Scrutinio D, Guida P et. al.

May 28th, 2020 - We investigated the performance of four prognostic tools in predicting 180-day mortality for patients admitted for decompensated heart failure (ADHF) by calculating sensitivity, specificity, positive predictive value (PPV), and negative predictive...

Klotho alleviates indoxyl sulfate-induced heart failure and kidney damage by promoting ...
https://doi.org/10.18632/aging.103183
Aging Lv J, Chen J et. al.

May 28th, 2020 - Indoxyl sulfate (IS) is a protein-bound uremic toxin that can accumulate in patients with chronic kidney disease (CKD) or acute kidney injury (AKI) and cause kidney and cardiac dysfunction. Klotho is an anti-aging protein that has reno- and cardio...

Self-Maintenance of Cardiac Resident Reparative Macrophages Attenuates Doxorubicin-indu...
https://doi.org/10.1161/CIRCRESAHA.119.316428
Circulation Research; Zhang H, Xu A et. al.

May 28th, 2020 - Rationale: Doxorubicin-induced cardiomyopathy (DiCM) is a primary cause of heart failure and mortality in cancer patients, in which macrophage-orchestrated inflammation serves as an essential pathological mechanism. However, the specific roles of ...

see more →

News  12,743 results

End-of-Life Care Disrupted in COVID-19 Crisis
https://www.medscape.com/viewarticle/931324

May 27th, 2020 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. An elderly man with congestive heart failure was getting worse, but fear of going to the emergency department during the COVID-19 public health cr...

Heart Failure Prevention Post–Myocardial Infarction: 5 Things to Know
https://www.medscape.com/viewarticle/931015

May 27th, 2020 - Heart failure (HF), a common complication of myocardial infarction (MI), occurs in 14%-36% of hospitalized patients. Patients with HF can present with a wide spectrum of clinical severity, ranging from asymptomatic left ventricular (LV) dysfunctio...

American College of Cardiology Virtual Scientific Sessions 2020: Drug Therapy Highlights
https://www.medscape.com/viewarticle/930769

May 21st, 2020 - Related News Stories VICTORIA: Vericiguat Seen as Novel Success in Tough-to-Treat, High-Risk Heart Failure Rivaroxaban Plus Aspirin Safely Benefits PAD Patients After Limb Revascularization REDUCE-IT: CV Benefit of Icosapent Ethyl Directly Related...

Stem Cells Show Signal of Benefit in Microvascular Dysfunction
https://www.medscape.com/viewarticle/930782

May 19th, 2020 - Autologous CD34-positive stem cells may improve coronary flow reserve and angina symptoms in patients with microvascular dysfunction, proof-of-concept testing suggests. Evidence of microvascular dysfunction is present in about 50% to 70% of patien...

SGLT2 Inhibitor Therapy Could Curb Heart Failure Deaths
https://www.medscape.com/viewarticle/930517

May 14th, 2020 - NEW YORK (Reuters Health) — According to projections from a decision-analytical model, sodium-glucose co-transporter 2 (SGLT2) inhibitor therapy could be of great benefit in certain patients with heart failure. The findings show "that the addition...

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Patient Education  163 results see all →