ALLMedicine Cardiomyopathy Center

Jun 1st, 2020 - Dilated cardiomyopathy (DCM) refers to a spectrum of heterogeneous myocardial disorders characterized by ventricular dilation and depressed cardiac performance in the absence of hypertension, valvular, congenital, or ischemic heart diseases, and w...

Jun 1st, 2020 - Invasive Hemodynamics of Hypertrophic Cardiomyopathy: Exercise Versus Isoproterenol.|2020|Caravita S,Baratto C,Perego GB,Cecchi F,Crotti L,|

Jun 1st, 2020 - The pattern of myocardial fibrosis differs significantly between different cardiomyopathies. Fibrosis in hypertrophic cardiomyopathy (HCM) is characteristically as patchy and regional but in dilated cardiomyopathy (DCM) as diffuse and global. We s...

Jun 1st, 2020 - Biallelic damaging variants in ALPK3, encoding alpha-protein kinase 3, cause pediatric-onset cardiomyopathy with manifestations that are incompletely defined. We analyzed clinical manifestations of damaging biallelic ALPK3 variants in 19 pediatric...

May 31st, 2020 - We aimed to assess long-term outcomes in S-ICD recipients with structural heart disease, especially focusing on shock incidence, predictors and associated prognoses. In this multicenter registry-based study, we retrospectively included all patient...

May 21st, 2019 - Question Is it possible to identify most patients with hypertrophic cardiomyopathy (HCM) at risk of arrhythmic sudden cardiac death (SCD) and to prevent such events with prophylactic implantable cardioverter/defibrillators (ICDs)? Findings In t...

Aug 19th, 2018 - Chagas disease, resulting from the protozoan Trypanosoma cruzi, is an important cause of heart failure, stroke, arrhythmia, and sudden death. Traditionally regarded as a tropical disease found only in Central America and South America, Chagas dise.

Jun 15th, 2018 - The purpose of this document is to provide updated guidance for the genetic evaluation of cardiomyopathy and for an approach to manage secondary findings from cardiomyopathy genes. The genetic bases of the primary cardiomyopathies (dilated, hypert...

Dec 31st, 2017 - Chagas disease (ChD) is a significant public health problem in mostLatin American countries. Observed mainly in rural areas, in recentdecades it has spread to cities and to nonendemic countries, mostlyas a result of migration of infected people.

Jul 31st, 2017 - Lightning strikes are a common and leading cause of morbidity and mortality. Multiple organ systems can be involved, though the effects of the electrical current on the cardiovascular system are one of the main modes leading to cardiorespiratory a...

Jun 1st, 2020 - Dilated cardiomyopathy (DCM) refers to a spectrum of heterogeneous myocardial disorders characterized by ventricular dilation and depressed cardiac performance in the absence of hypertension, valvular, congenital, or ischemic heart diseases, and w...

Jun 1st, 2020 - Invasive Hemodynamics of Hypertrophic Cardiomyopathy: Exercise Versus Isoproterenol.|2020|Caravita S,Baratto C,Perego GB,Cecchi F,Crotti L,|

Jun 1st, 2020 - The pattern of myocardial fibrosis differs significantly between different cardiomyopathies. Fibrosis in hypertrophic cardiomyopathy (HCM) is characteristically as patchy and regional but in dilated cardiomyopathy (DCM) as diffuse and global. We s...

Jun 1st, 2020 - Biallelic damaging variants in ALPK3, encoding alpha-protein kinase 3, cause pediatric-onset cardiomyopathy with manifestations that are incompletely defined. We analyzed clinical manifestations of damaging biallelic ALPK3 variants in 19 pediatric...

May 31st, 2020 - We aimed to assess long-term outcomes in S-ICD recipients with structural heart disease, especially focusing on shock incidence, predictors and associated prognoses. In this multicenter registry-based study, we retrospectively included all patient...

May 25th, 2020 - An investigational, first-in-class agent showed hypothesis-generating promise in symptomatic adults with nonobstructive hypertrophic cardiomyopathy (HCM), a condition lacking in good treatment options, in an early dose-finding study. The 40 patien...

May 21st, 2020 - Hypertrophic cardiomyopathy (HCM) is the most common inherited monogenic cardiac disorder, affecting 0.2-0.5% of the population.[1,2] In the United States, 750,000 people are estimated to have HCM; however, only approximately 100,000 people have b...

May 14th, 2020 - NEW YORK (Reuters Health) — According to projections from a decision-analytical model, sodium-glucose co-transporter 2 (SGLT2) inhibitor therapy could be of great benefit in certain patients with heart failure. The findings show "that the addition...

May 11th, 2020 - Acute heart failure is characterized by rapid onset or deterioration of symptoms and/or signs of heart failure, frequently with decompensation of preexisting cardiomyopathy. It is a life-threatening medical emergency. Globally, both in-hospital an...

May 11th, 2020 - Patients with obstructive hypertrophic cardiomyopathy (HCM) who took an investigational agent that targets cardiac myosin over about 7 months showed across-the-board improvements in functional capacity, symptoms, and left ventricular outflow obstr...