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About 7,205 results

ALLMedicine™ Hypertrophic Cardiomyopathy Center

Research & Reviews  2,647 results

The modified US heart allocation system improves transplant rates and decreases status ...
https://doi.org/10.1016/j.healun.2021.06.018
The Journal of Heart and Lung Transplantation : the Offic... Fowler CC, Helmers MR et. al.

Aug 2nd, 2021 - On October 18, 2018, the US heart allocation policy was restructured to improve transplant waitlist outcomes. Previously, hypertrophic cardiomyopathy (HCM) patients experienced significant waitlist mortality and functional decline, often requiring...

Invasive Assessment of Microvascular Resistance in Hypertrophic Cardiomyopathy With Ech...
https://doi.org/10.1016/j.hlc.2021.07.002
Heart, Lung & Circulation; Bakar SN, Hayman S et. al.

Aug 2nd, 2021 - Hypertrophic cardiomyopathy (HCM) is often associated with ischaemia despite lack of focal epicardial coronary stenosis. Our aim was to assess invasive coronary microvascular circulation and correlate findings with echocardiography. We prospective...

RBM20 is a candidate gene for hypertrophic cardiomyopathy.
https://doi.org/10.1016/j.cjca.2021.07.014
The Canadian Journal of Cardiology; Dai J, Li Z et. al.

Aug 2nd, 2021 - The genetic basis of a considerable fraction of hypertrophic cardiomyopathy (HCM) cases remains unknown. Whether the gene encoding RNA Binding Motif Protein 20 (RBM20) is implicated in HCM and the correlation of clinical characteristics of RBM20 h...

Variation p.R1045H in MYH7 correlated with hypertrophic cardiomyopathy in a Chinese ped...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8325323
BMC Medical Genomics; Zhang Y, Shang Y et. al.

Aug 1st, 2021 - Inherited hypertrophic cardiomyopathy (HCM) is a common heart muscle disease that damages heart function and may cause the heart to suddenly stop beating. Genetic factors play an important role in HCM. Pedigree analysis is a good way to identify t...

Early outcomes of septal myectomy for obstructive hypertrophic cardiomyopathy in childr...
https://doi.org/10.1053/j.semtcvs.2021.07.027
Seminars in Thoracic and Cardiovascular Surgery; Chen S, Chen L et. al.

Jul 30th, 2021 - Noonan syndrome (NS) is a genetic syndrome causing obstructive hypertrophic cardiomyopathy (HCM) in infants. Studies of cardiac surgery in pediatric HCM patients with NS (NS-HCM) are lacking. We aim to characterize the early disease course of youn...

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Guidelines  8 results

2020 AHA/ACC guideline for the diagnosis and treatment of patients with hypertrophic ca...
https://doi.org/10.1016/j.jtcvs.2021.04.001
The Journal of Thoracic and Cardiovascular Surgery; , Ommen SR et. al.

May 1st, 2021 - 2020 AHA/ACC guideline for the diagnosis and treatment of patients with hypertrophic cardiomyopathy: A report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.|2021| ,Ommen SR,Mital S...

ACR Appropriateness Criteria® Nonischemic Myocardial Disease with Clinical Manifestatio...
https://doi.org/10.1016/j.jacr.2021.01.019
Journal of the American College of Radiology : JACR; , Rajiah P et. al.

Mar 3rd, 2021 - Nonischemic cardiomyopathies encompass a broad spectrum of myocardial disorders with mechanical or electrical dysfunction without evidence of ischemia. There are five broad variants of nonischemic cardiomyopathies; hypertrophic cardiomyopathy (Var...

2020 AHA/ACC Guideline for the Diagnosis and Treatment of Patients With Hypertrophic Ca...
https://doi.org/10.1016/j.jacc.2020.08.045
Journal of the American College of Cardiology; Ommen SR, Mital S et. al.

Nov 25th, 2020 - 2020 AHA/ACC Guideline for the Diagnosis and Treatment of Patients With Hypertrophic Cardiomyopathy: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.|2020|Ommen SR,Mital S,B...

2020 AHA/ACC Guideline for the Diagnosis and Treatment of Patients With Hypertrophic Ca...
https://doi.org/10.1016/j.jacc.2020.08.044
Journal of the American College of Cardiology; Ommen SR, Mital S et. al.

Nov 25th, 2020 - This executive summary of the hypertrophic cardiomyopathy clinical practice guideline provides recommendations and algorithms for clinicians to diagnose and manage hypertrophic cardiomyopathy in adult and pediatric patients as well as supporting d...

Guidelines for Diagnosis and Treatment of Patients With Hypertrophic Cardiomyopathy (JC...
https://doi.org/10.1253/circj.CJ-66-0122
Circulation Journal : Official Journal of the Japanese Ci...

Feb 5th, 2016 - Guidelines for Diagnosis and Treatment of Patients With Hypertrophic Cardiomyopathy (JCS 2012) - Digest Version .|2016| ,|diagnosis,physiopathology,therapy,

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Drugs  6 results see all →

Clinicaltrials.gov  64 results

Arrhythmogenic Substrate in Primary Cardiomyopathies
https://clinicaltrials.gov/ct2/show/NCT03304847

Mar 26th, 2020 - The present study is designed as a prospective single center study. All selected patients with implanted ICD to prevent VT/VF recurrence who are referred to the Arrhythmology Department of San Donato Milanese Hospital, for the management of a prim...

High Intensity Exercise for Increasing Fitness in Patients With Hypertrophic Cardiomyopathy
https://clinicaltrials.gov/ct2/show/NCT03335332

Mar 18th, 2020 - Regular exercise reduces the risk of all-cause and cardiovascular mortality in the general population. Specifically, higher cardiorespiratory fitness is associated with a 10 - 20 % reduction in mortality risk for every 1 MET (metabolic equivalent ...

Differentiating Hypertrophic Cardiomyopathy From Hypertensive Heart Disease
https://clinicaltrials.gov/ct2/show/NCT03271385

Mar 4th, 2020 - Both hypertrophic cardiomyopathy (HCM) and hypertensive heart disease (HHD) present left ventricular hypertrophy (LVH), but the prognosis varies. Nevertheless, the feasibility of distinguishing these two conditions is limited by the fact that over...

Microvascular Dysfunction in Nonischemic Cardiomyopathy: Insights From CMR Assessment of Coronary Flow Reserve
https://clinicaltrials.gov/ct2/show/NCT03249272

Dec 13th, 2019 - Coronary microvascular dysfunction (MVD) has been implicated as an important marker of cardiac risk and has been thought to directly contribute to the pathogenesis of a wide variety of cardiomyopathies. For instance, MVD is believed to cause ische...

Routine vs Selective Cardiac Magnetic Resonance in Non-Ischemic Heart Failure
https://clinicaltrials.gov/ct2/show/NCT01281384

Nov 21st, 2019 - Primary objective: to compare the effect of routine cardiac magnetic resonance (CMR) versus standard care (i.e. echocardiography with only selective use of CMR) on the etiological diagnosis in patients with a non-ischemic heart failure (HF). The p...

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News  143 results

High-Intensity Exercise Safe and Effective in HCM Patients
https://www.medscape.com/viewarticle/952866

Jun 10th, 2021 - Patients with hypertrophic cardiomyopathy (HCM) can not only safely complete a high-intensity exercise programme but experience significant improvements in fitness, cardiovascular risk, and psychological outcomes, say UK researchers. Dr Joyee Basu...

Pathogenic Variants Tied to Unexplained Sudden Cardiac Death in US Adults
https://www.medscape.com/viewarticle/952606

Jun 8th, 2021 - NEW YORK (Reuters Health) - Close to 20% of U.S. adults dying from unexplained sudden cardiac death (SCD) carried pathogenic or likely pathogenic (P/LP) variants of inherited cardiomyopathies (CMs) and arrhythmia syndromes in a large genetic assoc...

Mavacamten Boosts Quality of Life in Hypertrophic Cardiomyopathy
https://www.medscape.com/viewarticle/952563

Jun 7th, 2021 - Of patients with symptomatic, obstructive hypertrophic cardiomyopathy treated with the investigational oral agent mavacamten, more than twice as many, compared with placebo, had a very large improvement from baseline in their summary quality of li...

New HCM Guidelines Make Shared Decision-making Top Priority
https://www.medscape.com/viewarticle/941365

Nov 20th, 2020 - Greater involvement of the patient and family in decision-making, clarity on the role of genetic testing and parameters for team-oriented care, and use of high-volume specialty centers are cornerstones of the first update in almost a decade of the...

Surgery Still Best Option in Obstructive HCM Despite EXPLORER-HCM Results
https://www.medscape.com/viewarticle/939029

Oct 15th, 2020 - Among the landmark presentations at the recent European Society of Cardiology virtual congress was the presentation on the EXPLORER-HCM randomized controlled trial. In this study, simultaneously published in The Lancet, the investigational drug ma...

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Patient Education  14 results see all →