ALLMedicine™ Hypertrophic Cardiomyopathy Center
Research & Reviews 7,033 results
https://doi.org/10.1093/hmg/ddab010
Human Molecular Genetics; Fukuzawa A, Koch D et. al.
Jan 13th, 2021 - Obscurin is a giant muscle protein that connects the sarcomere with the sarcoplasmic reticulum, with poorly understood structural and signalling functions. Increasingly, obscurin variants are implicated in the pathophysiology of cardiovascular dis...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797548
International Journal of Medical Sciences; Liu L, Liu Z et. al.
Jan 13th, 2021 - Hypertrophic cardiomyopathy (HCM) is an inherited cardiac disease, which has a marked heterogeneity in clinical expression, natural history, and prognosis. HCM is associated with a high prevalence of thromboembolic events (stroke and systemic embo...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797532
International Journal of Medical Sciences; Jensen CJ, Lambers M et. al.
Jan 13th, 2021 - Objective: We sought to investigate the possible association of a wide QRS-T angle on the surface EKG and myocardial fibrosis on contrast-enhanced cardiovascular magnetic (CMR) imaging in patients with hypertrophic cardiomyopathy (HCM). Background...
https://doi.org/10.1053/j.jvca.2020.12.014
Journal of Cardiothoracic and Vascular Anesthesia; Moreno Garijo J, Amador Y et. al.
Jan 12th, 2021 - Determine whether the intraoperative three-dimensional left ventricular outflow tract cross-sectional area may be inversely correlated with pressure gradients as a determinant of surgical success after septal myectomy in hypertrophic cardiomyopath...
https://doi.org/10.1161/CIRCHEARTFAILURE.120.008006
Circulation. Heart Failure; Margulies KB, Prosser BL
Jan 12th, 2021 - Tubulin Detyrosination: An Emerging Therapeutic Target in Hypertrophic Cardiomyopathy.|2021|Margulies KB,Prosser BL,|
Guidelines 15 results
https://jamanetwork.com/journals/jamacardiology/fullarticle/2733139
May 21st, 2019 - Question Is it possible to identify most patients with hypertrophic cardiomyopathy (HCM) at risk of arrhythmic sudden cardiac death (SCD) and to prevent such events with prophylactic implantable cardioverter/defibrillators (ICDs)? Findings In t...
https://doi.org/10.1253/circj.CJ-66-0122
Circulation Journal : Official Journal of the Japanese Circulation Society;
Feb 4th, 2016 - Guidelines for Diagnosis and Treatment of Patients With Hypertrophic Cardiomyopathy (JCS 2012) - Digest Version .|2016| ,|diagnosis,physiopathology,therapy,
https://doi.org/10.1093/eurheartj/ehu284
European Heart Journal; , Elliott PM et. al.
Aug 31st, 2014 - 2014 ESC Guidelines on diagnosis and management of hypertrophic cardiomyopathy: the Task Force for the Diagnosis and Management of Hypertrophic Cardiomyopathy of the European Society of Cardiology (ESC).|2014| ,Elliott PM,Anastasakis A,Borger MA,B...
https://doi.org/10.1016/j.jtcvs.2011.10.019
The Journal of Thoracic and Cardiovascular Surgery; , et. al.
Nov 18th, 2011 - 2011 ACCF/AHA guideline for the diagnosis and treatment of hypertrophic cardiomyopathy: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines.|2011| , , , , ,|diag...
https://doi.org/10.1016/j.jacc.2011.06.011
Journal of the American College of Cardiology; Gersh BJ, Maron BJ et. al.
Nov 14th, 2011 - 2011 ACCF/AHA Guideline for the Diagnosis and Treatment of Hypertrophic Cardiomyopathy: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Developed in collaboration with the Ame...
Clinicaltrials.gov 7,227 results
https://doi.org/10.1093/hmg/ddab010
Human Molecular Genetics; Fukuzawa A, Koch D et. al.
Jan 13th, 2021 - Obscurin is a giant muscle protein that connects the sarcomere with the sarcoplasmic reticulum, with poorly understood structural and signalling functions. Increasingly, obscurin variants are implicated in the pathophysiology of cardiovascular dis...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797548
International Journal of Medical Sciences; Liu L, Liu Z et. al.
Jan 13th, 2021 - Hypertrophic cardiomyopathy (HCM) is an inherited cardiac disease, which has a marked heterogeneity in clinical expression, natural history, and prognosis. HCM is associated with a high prevalence of thromboembolic events (stroke and systemic embo...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797532
International Journal of Medical Sciences; Jensen CJ, Lambers M et. al.
Jan 13th, 2021 - Objective: We sought to investigate the possible association of a wide QRS-T angle on the surface EKG and myocardial fibrosis on contrast-enhanced cardiovascular magnetic (CMR) imaging in patients with hypertrophic cardiomyopathy (HCM). Background...
https://doi.org/10.1053/j.jvca.2020.12.014
Journal of Cardiothoracic and Vascular Anesthesia; Moreno Garijo J, Amador Y et. al.
Jan 12th, 2021 - Determine whether the intraoperative three-dimensional left ventricular outflow tract cross-sectional area may be inversely correlated with pressure gradients as a determinant of surgical success after septal myectomy in hypertrophic cardiomyopath...
https://doi.org/10.1161/CIRCHEARTFAILURE.120.008006
Circulation. Heart Failure; Margulies KB, Prosser BL
Jan 12th, 2021 - Tubulin Detyrosination: An Emerging Therapeutic Target in Hypertrophic Cardiomyopathy.|2021|Margulies KB,Prosser BL,|
News 205 results
https://www.medscape.com/viewarticle/941365
Nov 19th, 2020 - Greater involvement of the patient and family in decision-making, clarity on the role of genetic testing and parameters for team-oriented care, and use of high-volume specialty centers are cornerstones of the first update in almost a decade of the...
https://www.staging.medscape.com/viewarticle/939029
Oct 14th, 2020 - Among the landmark presentations at the recent European Society of Cardiology virtual congress was the presentation on the EXPLORER-HCM randomized controlled trial. In this study, simultaneously published in The Lancet, the investigational drug ma...
https://www.medscape.com/viewarticle/939029
Oct 14th, 2020 - Among the landmark presentations at the recent European Society of Cardiology virtual congress was the presentation on the EXPLORER-HCM randomized controlled trial. In this study, simultaneously published in The Lancet, the investigational drug ma...
https://www.staging.medscape.com/viewarticle/936542
Aug 28th, 2020 - An investigational drug that targets part of the molecular machinery underlying obstructive hypertrophic cardiomyopathy (HCM) can improve both symptoms and functional status in patients with the genetic disorder, suggests a placebo-controlled phas...
https://www.medscape.com/viewarticle/936542
Aug 28th, 2020 - An investigational drug that targets part of the molecular machinery underlying obstructive hypertrophic cardiomyopathy (HCM) can improve both symptoms and functional status in patients with the genetic disorder, suggests a placebo-controlled phas...