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About 7,778 results

ALLMedicine™ Hypertrophic Cardiomyopathy Center

Research & Reviews  2,837 results

Moderate Intensity Training in Patients With Truncating Genetic Variants in TTN.
https://clinicaltrials.gov/ct2/show/NCT05180188

Jan 21st, 2022 - Mutations leading to truncations of the large sarcomeric protein titin was discovered in 2012 as the most prevalent genetic cause of familial dilated cardiomyopathy, affecting approximately 25% of all cases of familial dilated cardiomyopathy. The ...

Impact of Body Mass Index on Postoperative Atrial Fibrillation in Patients With Hypertr...
https://doi.org/10.1161/JAHA.121.023152
Journal of the American Heart Association; Zhang J, Zhu C et. al.

Jan 20th, 2022 - Background Obesity is an established cardiovascular risk factor in patients with hypertrophic cardiomyopathy. Postoperative atrial fibrillation (POAF) is one of the most common complications after surgery in patients with obstructive hypertrophic ...

Outcomes and Revascularization Strategies of ST-Elevation Myocardial Infarction in Pati...
https://doi.org/10.1016/j.cpcardiol.2022.101102
Current Problems in Cardiology; Ariss RW, Khan Minhas AM et. al.

Jan 19th, 2022 - Myocardial ischemia is a known complication of HCM. Contemporary outcomes and care processes after STEMI are extensively examined; however, there are limited data on outcomes and revascularization strategies of HCM patients with STEMI. The Nationa...

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Guidelines  8 results

2020 AHA/ACC guideline for the diagnosis and treatment of patients with hypertrophic ca...
https://doi.org/10.1016/j.jtcvs.2021.04.001
The Journal of Thoracic and Cardiovascular Surgery; , Ommen SR et. al.

May 1st, 2021 - 2020 AHA/ACC guideline for the diagnosis and treatment of patients with hypertrophic cardiomyopathy: A report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.|2021| ,Ommen SR,Mital S...

ACR Appropriateness Criteria® Nonischemic Myocardial Disease with Clinical Manifestatio...
https://doi.org/10.1016/j.jacr.2021.01.019
Journal of the American College of Radiology : JACR; , Rajiah P et. al.

Mar 3rd, 2021 - Nonischemic cardiomyopathies encompass a broad spectrum of myocardial disorders with mechanical or electrical dysfunction without evidence of ischemia. There are five broad variants of nonischemic cardiomyopathies; hypertrophic cardiomyopathy (Var...

2020 AHA/ACC Guideline for the Diagnosis and Treatment of Patients With Hypertrophic Ca...
https://doi.org/10.1016/j.jacc.2020.08.045
Journal of the American College of Cardiology; Ommen SR, Mital S et. al.

Nov 25th, 2020 - 2020 AHA/ACC Guideline for the Diagnosis and Treatment of Patients With Hypertrophic Cardiomyopathy: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.|2020|Ommen SR,Mital S,B...

2020 AHA/ACC Guideline for the Diagnosis and Treatment of Patients With Hypertrophic Ca...
https://doi.org/10.1016/j.jacc.2020.08.044
Journal of the American College of Cardiology; Ommen SR, Mital S et. al.

Nov 25th, 2020 - This executive summary of the hypertrophic cardiomyopathy clinical practice guideline provides recommendations and algorithms for clinicians to diagnose and manage hypertrophic cardiomyopathy in adult and pediatric patients as well as supporting d...

Guidelines for Diagnosis and Treatment of Patients With Hypertrophic Cardiomyopathy (JC...
https://doi.org/10.1253/circj.CJ-66-0122
Circulation Journal : Official Journal of the Japanese Ci...

Feb 5th, 2016 - Guidelines for Diagnosis and Treatment of Patients With Hypertrophic Cardiomyopathy (JCS 2012) - Digest Version .|2016| ,|diagnosis,physiopathology,therapy,

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Drugs  5 results see all →

Clinicaltrials.gov  52 results

Moderate Intensity Training in Patients With Truncating Genetic Variants in TTN.
https://clinicaltrials.gov/ct2/show/NCT05180188

Jan 21st, 2022 - Mutations leading to truncations of the large sarcomeric protein titin was discovered in 2012 as the most prevalent genetic cause of familial dilated cardiomyopathy, affecting approximately 25% of all cases of familial dilated cardiomyopathy. The ...

Artificial Intelligence Guided Echocardiographic Screening of Rare Diseases (EchoNet-Screening)
https://clinicaltrials.gov/ct2/show/NCT05139797

Jan 19th, 2022 - Despite rapidly advancing developments in targeted therapeutics and genetic sequencing, persistent limits in the accuracy and throughput of clinical phenotyping has led to a widening gap between the potential and the actual benefits realized by pr...

A Prospective Incident Study of Arrhythmias in Hypertrophic Cardiomyopathy
https://clinicaltrials.gov/ct2/show/NCT04112290

Jan 14th, 2022 - Adult patients with hypertrophic cardiomyopathy and without known atrial fibrillation or pacemaker/implantable cardiac defibrillation will undergo implantable loop recorder implantation. No direct interventions will be performed. Prospective obser...

Comparison of Squat-to-Stand Maneuver With Amyl Nitrite, Valsalva, and Exercise Stress Echocardiography in Inducing Latent Left Ventricular Outflow Obstruction in Hypertrophic Cardiomyopathy
https://clinicaltrials.gov/ct2/show/NCT04905173

Jan 11th, 2022 - Left ventricular hypertrophy and abnormal ventricular configuration result in dynamic left ventricular outflow obstruction in ~75% of HCM patients, which is associated with increased cardiac morbidity and mortality. However, the dynamic nature of ...

A Phase I Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of CT-G20 in Subjects With Obstructive Hypertrophic Cardiomyopathy
https://clinicaltrials.gov/ct2/show/NCT04418297

Dec 29th, 2021 - This is a randomized, double-blind, placebo-controlled, sequential, 5-day treatment, ascending dose study in subjects with obstructive HCM aged 18-70 years. The purpose of this study is to assess the safety, tolerability, pharmacokinetics and phar...

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News  194 results

Cardiologist's Omicron Recovery; Public AEDs MIA; Language Barrier to CVD Reporting?
https://www.medpagetoday.com/cardiology/prevention/96191

Dec 14th, 2021 - COVID-19 infection was associated with just 40 myocarditis cases per 1 million people in a large study from England. The risk of heart inflammation was several-fold lower after vaccination, researchers noted. (Nature Medicine) Israeli intervention...

Hypertrophic Cardiomyopathy: Do New Markers Enhance Current Risk-Stratification Models?
https://www.medscape.com/viewarticle/959790

Oct 5th, 2021 - Hypertrophic cardiomyopathy (HCM) is the most common form of hereditary heart disease, affecting 1 in 200-500 people. Of all the heterogenous manifestations associated with HCM, including left ventricular outflow tract obstruction and heart failur...

Genetic Testing in Early AF May Reveal More Serious Congenital Problems
https://www.medscape.com/viewarticle/959009

Sep 22nd, 2021 - NEW YORK (Reuters Health) - Genetic testing in patients with early-onset atrial fibrillation (AF) identified a more serious disease-associated variant in 10% of cases, researchers found. "Research over the past several years has raised the concern...

Another Myosin Inhibitor Raises Hopes for Obstructive HCM in Early Study
https://www.medscape.com/viewarticle/958638

Sep 13th, 2021 - DENVER — Patients with obstructive hypertrophic cardiomyopathy (HCM) treated with an agent that targets the disorder's underlying disease process showed important gains in hemodynamics and other benefits, with few adverse effects, in a small phase...

Novel Mutation May Be Unrecognized Cause of Sudden Infant Death
https://www.medscape.com/viewarticle/957129

Aug 24th, 2021 - A previously healthy infant who survived sudden cardiac arrest at home was later found to have a de novo likely pathogenic genetic mutation in the SOS1 gene, which might be an unrecognized cause of sudden infant death, report clinicians from Misso...

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Patient Education  15 results see all →