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About 3,738 results

ALLMedicine™ Myopathies Center

Research & Reviews  1,410 results

Ultrasound evaluation of diaphragm motion in BAG-3 myofibrillar myopathy: A case report.
https://doi.org/10.1097/MD.0000000000028484
Medicine Zhan L, Lv L et. al.

Jan 15th, 2022 - Mutations in Bcl-2-associated athanogene-3 (BAG-3) can cause a rare subtype of myofibrillar myopathies (MFMs), characterized by progressive muscle weakness, cardiomyopathy, and severe respiratory insufficiency in childhood. Little is known about d...

Autoantibodies against Four-and-a-Half-LIM Domain 1 (FHL1) in Inflammatory Myopathies: ...
https://doi.org/10.1093/rheumatology/keac003
Rheumatology (Oxford, England); Galindo-Feria AS, Horuluoglu B et. al.

Jan 14th, 2022 - To determine the prevalence and associations of autoantibodies targeting a muscle-specific autoantigen, Four-and-a-half-LIM-domain 1 (FHL1), in South Australian patients with histologically-confirmed IIM and in patients with systemic sclerosis (SS...

Idiopathic inflammatory myopathies: CT characteristics of interstitial lung disease and...
https://doi.org/10.1007/s00330-021-08411-w 10.1016/j.chest.2016.04.007 10.1183/16000617.00002015 10.3233/JND-180308 10.1056/NEJM197502132920706 10.1093/qjmed/77.1.1019 10.1002/ana.410380504 10.1016/j.nmd.2004.02.006 10.1136/rmdopen-2017-000507 10.1111/joim.12451 10.1097/WCO.0000000000000376 10.1001/jamaneurol.2018.2598 10.1183/09031936.03.00026703 10.1164/ajrccm.164.7.2103110 10.1164/ajrccm/141.3.727 10.1016/j.resinv.2016.09.006 10.1016/j.rmed.2007.02.017 10.1002/art.23571 10.1016/S0720-048X(03)00094-9 10.1371/journal.pone.0098824 10.1016/j.chest.2020.01.033 10.1016/j.ejrad.2007.05.017 10.1164/rccm.201308-1483ST 10.1148/radiol.2462070712 10.1097/BOR.0000000000000537 10.1016/j.semarthrit.2020.11.009 10.1007/s12016-015-8510-y 10.1016/j.rmed.2011.05.006 10.1016/j.rmed.2016.10.019 10.1007/s40674-018-0110-6 10.1016/j.resinv.2018.07.007 10.1016/j.resinv.2016.08.007 10.1016/j.rmed.2013.01.014 10.1016/j.amjms.2017.07.013 10.1007/s12016-020-08822-5 10.1007/s11926-013-0359-6 10.1097/MCC.0000000000000373 10.1164/rccm.201508-1632OC 10.1007/s00330-019-06152-5 10.1016/j.ejrad.2014.11.026 10.1093/rheumatology/keaa372 10.1148/radiology.212.2.r99au05567
European Radiology; Laporte A, Mariampillai K et. al.

Jan 14th, 2022 - Interstitial lung disease (ILD), one of the most common extramuscular manifestations of idiopathic inflammatory myopathies (IIMs), carries a poor prognosis. Myositis-specific autoantibody (MSA)-positivity is a key finding for IIM diagnosis. We aim...

Targeting necroptosis in muscle fibers ameliorates inflammatory myopathies.
https://doi.org/10.1038/s41467-021-27875-4
Nature Communications; Kamiya M, Mizoguchi F et. al.

Jan 12th, 2022 - Muscle cell death in polymyositis is induced by CD8+ cytotoxic T lymphocytes. We hypothesized that the injured muscle fibers release pro-inflammatory molecules, which would further accelerate CD8+ cytotoxic T lymphocytes-induced muscle injury, and...

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Guidelines  2 results

2017 European League Against Rheumatism/American College of Rheumatology classification...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736307
Annals of the Rheumatic Diseases; Lundberg IE, Tjärnlund A et. al.

Oct 29th, 2017 - To develop and validate new classification criteria for adult and juvenile idiopathic inflammatory myopathies (IIM) and their major subgroups. Candidate variables were assembled from published criteria and expert opinion using consensus methodolog...

EFNS guidelines for the molecular diagnosis of neurogenetic disorders: motoneuron, peri...
https://doi.org/10.1111/j.1468-1331.2010.03069.x
European Journal of Neurology; Burgunder JM, Schöls L et. al.

May 27th, 2010 - These EFNS guidelines on the molecular diagnosis of motoneuron disorders, neuropathies and myopathies are designed to summarize the possibilities and limitations of molecular genetic techniques and to provide diagnostic criteria for deciding when ...

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Clinicaltrials.gov  31 results

Study of Families With Twins or Siblings Discordant for Rheumatic Disorders
https://clinicaltrials.gov/ct2/show/NCT00055055

Jan 12th, 2022 - Most autoimmune diseases are thought to develop as a result of chronic immune activation and dysregulation after selected environmental exposures in genetically susceptible individuals. Current evidence suggests that the adult and juvenile forms o...

Assessing Clinical Endpoints and Biomarkers in Myotonic Dystrophy Type-1 and Type 2 (ASCEND-DM)
https://clinicaltrials.gov/ct2/show/NCT03867435

Nov 4th, 2021 - Objective: Myotonic dystrophy type 1 (DM1) and type 2 (DM2) are the most common inherited skeletal myopathies in adults. RNA toxicity is the core disease mechanism, good molecular targets have been identified and there has been rapid progress in d...

Natural History Study of Patients With Centronuclear Myopathies
https://clinicaltrials.gov/ct2/show/NCT04977648

Oct 19th, 2021 - This is a prospective, longitudinal study of the natural disease course intended to recruit approximately 60 patients with centronuclear myopathies (CNM) in Europe and the United States. The duration of the study, including the enrollment period, ...

Molecular and Genetic Studies of Congenital Myopathies
https://clinicaltrials.gov/ct2/show/NCT00272883

Sep 8th, 2021 - The Congenital Myopathy Research Program consists of a group of scientists and healthcare providers all working to better understand the congenital myopathies. We are taking two approaches to reach our research goals. The first involves identifyin...

Clinical Database and Biobank of Patients With Inflammatory Myopathies: the MASC Project (Myositis, DNA, Serum, Cells) (MASC)
https://clinicaltrials.gov/ct2/show/NCT04637672

Sep 2nd, 2021 - Myositis is a rare autoimmune disease in which the immune system mistakenly attacks the patient's own peripheral muscles. This aggression manifests by muscle inflammation and necrosis responsible for a motor deficit of varying severity. The treatm...

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News  48 results

Pneumocystis Often Lethal in Dermatomyositis
https://www.medpagetoday.com/rheumatology/generalrheumatology/94445

Sep 10th, 2021 - Patients with dermatomyositis who were positive for a myositis-specific antibody had a much higher incidence of and mortality associated with Pneumocystis jirovecii infection than patients with other antibody-negative idiopathic inflammatory myopa...

Another Trial Backs Statin Safety
https://www.medpagetoday.com/cardiology/prevention/91356

Feb 25th, 2021 - Close on the heels of SAMSON, a series of randomized "n-of-1" trials showed no difference in muscle symptoms when people were put on a statin versus a placebo. People who had previously reported statin myopathies ended up rating muscle symptoms si...

Environmental Factors in Myositis: A Link?
https://www.medpagetoday.com/rheumatology/generalrheumatology/87118

Jun 17th, 2020 - The development of a subtype of inflammatory myopathy characterized by interstitial lung disease and positivity for a specific autoantibody was influenced by seasonality and place of residence, Japanese researchers found. Among patients with polym...

Congenital myasthenic syndrome diagnosed best with repetitive stimulation and jitter analysis
https://www.mdedge.com/neurology/article/210304/neuromuscular-disorders/congenital-myasthenic-syndrome-diagnosed-best?channel=53
Tara Haelle

Oct 17th, 2019 - AUSTIN, TEX. – The use of both repetitive stimulation (RS) and jitter analysis are important for accurate diagnosis of congenital myasthenic syndrome (CMS) suggests newly presented research.

Congenital myasthenic syndrome diagnosed best with repetitive stimulation and jitter analysis
https://www.mdedge.com/neurology/article/210304/neuromuscular-disorders/congenital-myasthenic-syndrome-diagnosed-best
Tara Haelle

Oct 17th, 2019 - AUSTIN, TEX. – The use of both repetitive stimulation (RS) and jitter analysis are important for accurate diagnosis of congenital myasthenic syndrome (CMS) suggests newly presented research.

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Patient Education  4 results see all →