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About 4,510 results

ALLMedicine™ Myopathies Center

Research & Reviews  1,645 results

Amelioration of inflammatory myopathies by glucagon-like peptide-1 receptor agonist via...
https://doi.org/10.1002/jcsm.13025
Journal of Cachexia, Sarcopenia and Muscle; Kamiya M, Mizoguchi F et. al.

Jul 2nd, 2022 - As glucocorticoids induce muscle atrophy during the treatment course of polymyositis (PM), novel therapeutic strategy is awaited that suppresses muscle inflammation but retains muscle strength. We recently found that injured muscle fibres in PM un...

Studies of the Natural History and Pathogenesis of Autoimmune/Connective Tissue Diseases
https://clinicaltrials.gov/ct2/show/NCT00341679

Jul 1st, 2022 - Individuals who develop chronic harmful inflammation in association with self-reactive autoantibodies or T cells are said to have autoimmune diseases. The causes of these diseases are unknown but they are thought to occur in genetically susceptibl...

Novel PET Radioligands as Inflammatory Biomarkers in Rheumatoid Arthritis and Myositis
https://clinicaltrials.gov/ct2/show/NCT03912428

Jul 1st, 2022 - I. Objective 18-kDa translocator protein (TSPO) and cyclooxygenase-2 (COX-2) are both implicated in the pathophysiology of various inflammatory disorders, suggesting that both may serve as potential biomarkers of inflammation in brain as well as p...

Study of Families With Twins or Siblings Discordant for Rheumatic Disorders
https://clinicaltrials.gov/ct2/show/NCT00055055

Jul 1st, 2022 - Most autoimmune diseases are thought to develop as a result of chronic immune activation and dysregulation after selected environmental exposures in genetically susceptible individuals. Current evidence suggests that the adult and juvenile forms o...

Study and Treatment of Inflammatory Muscle Diseases
https://clinicaltrials.gov/ct2/show/NCT00001265

Jul 1st, 2022 - Polymyositis, dermatomyositis and related disorders, also known as the idiopathic inflammatory myopathies (IIM), are an uncommon, heterogeneous group of diseases. This is an omnibus protocol designed to continue our description of this rare group ...

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Guidelines  2 results

2017 European League Against Rheumatism/American College of Rheumatology classification...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736307
Annals of the Rheumatic Diseases; Lundberg IE, Tjärnlund A et. al.

Oct 29th, 2017 - To develop and validate new classification criteria for adult and juvenile idiopathic inflammatory myopathies (IIM) and their major subgroups. Candidate variables were assembled from published criteria and expert opinion using consensus methodolog...

EFNS guidelines for the molecular diagnosis of neurogenetic disorders: motoneuron, peri...
https://doi.org/10.1111/j.1468-1331.2010.03069.x
European Journal of Neurology; Burgunder JM, Schöls L et. al.

May 27th, 2010 - These EFNS guidelines on the molecular diagnosis of motoneuron disorders, neuropathies and myopathies are designed to summarize the possibilities and limitations of molecular genetic techniques and to provide diagnostic criteria for deciding when ...

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Clinicaltrials.gov  95 results

Studies of the Natural History and Pathogenesis of Autoimmune/Connective Tissue Diseases
https://clinicaltrials.gov/ct2/show/NCT00341679

Jul 1st, 2022 - Individuals who develop chronic harmful inflammation in association with self-reactive autoantibodies or T cells are said to have autoimmune diseases. The causes of these diseases are unknown but they are thought to occur in genetically susceptibl...

Novel PET Radioligands as Inflammatory Biomarkers in Rheumatoid Arthritis and Myositis
https://clinicaltrials.gov/ct2/show/NCT03912428

Jul 1st, 2022 - I. Objective 18-kDa translocator protein (TSPO) and cyclooxygenase-2 (COX-2) are both implicated in the pathophysiology of various inflammatory disorders, suggesting that both may serve as potential biomarkers of inflammation in brain as well as p...

Study and Treatment of Inflammatory Muscle Diseases
https://clinicaltrials.gov/ct2/show/NCT00001265

Jul 1st, 2022 - Polymyositis, dermatomyositis and related disorders, also known as the idiopathic inflammatory myopathies (IIM), are an uncommon, heterogeneous group of diseases. This is an omnibus protocol designed to continue our description of this rare group ...

A Study of Nipocalimab in Participants With Active Idiopathic Inflammatory Myopathies
https://clinicaltrials.gov/ct2/show/NCT05379634

Jul 1st, 2022 - IIM is considered as a group of rare diseases that is characterized by common features of insidious painless, proximal skeletal muscle weakness, low endurance, and elevated serum muscle enzyme levels. Due to muscle weakness and progressive muscula...

Study of Families With Twins or Siblings Discordant for Rheumatic Disorders
https://clinicaltrials.gov/ct2/show/NCT00055055

Jul 1st, 2022 - Most autoimmune diseases are thought to develop as a result of chronic immune activation and dysregulation after selected environmental exposures in genetically susceptible individuals. Current evidence suggests that the adult and juvenile forms o...

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News  59 results

Myositis guidelines aim to standardize adult and pediatric care
https://www.mdedge.com/rheumatology/article/254607/lupus-connective-tissue-diseases/myositis-guidelines-aim-standardize
Sara Freeman

May 13th, 2022 - All patients with idiopathic inflammatory myopathies (IIM) should be screened for swallowing difficulties, according to the first evidence-based guideline to be produced. The guideline, which has been developed by a working group of the British So.

Myositis Guidelines Aim to Standardize Adult and Pediatric Care
https://www.medscape.com/viewarticle/973968

May 13th, 2022 - All patients with idiopathic inflammatory myopathies (IIM) should be screened for swallowing difficulties, according to the first evidence-based guideline to be produced. The guideline, which has been developed by a working group of the British So...

Predicting Treatment Response in Inflammatory Muscle Disorders
https://www.medpagetoday.com/rheumatology/generalrheumatology/97219

Feb 16th, 2022 - Rheumatologists looking for clues to whether their patients with certain inflammatory myopathies will improve on immunosuppressive drugs may find them in a new study appearing in Arthritis Care & Research. Presence of dermatomyositis-specific auto...

 Muscle-wasting Conditions May be More Common in the UK Than Previous Estimates
https://www.medscape.com/viewarticle/968599

Feb 16th, 2022 - Tens of thousands more people in the UK could be living with neuromuscular disease (NMD) than previous estimates suggested, according to new research. A study in the journal PLOS ONE, which analysed millions of GP records, suggested that the preva...

Another Trial Backs Statin Safety
https://www.medpagetoday.com/cardiology/prevention/91356

Feb 25th, 2021 - Close on the heels of SAMSON, a series of randomized "n-of-1" trials showed no difference in muscle symptoms when people were put on a statin versus a placebo. People who had previously reported statin myopathies ended up rating muscle symptoms si...

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Patient Education  3 results see all →