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About 1,445 results

ALLMedicine™ Thoracic Aortic Aneurysm Center

Research & Reviews  531 results

Inhibition of HIPK2 Alleviates Thoracic Aortic Disease in Mice With Progressively Sever...
https://doi.org/10.1161/ATVBAHA.121.316464
Arteriosclerosis, Thrombosis, and Vascular Biology; Caescu CI, Hansen J et. al.

Jul 30th, 2021 - Despite considerable research, the goal of finding nonsurgical remedies against thoracic aortic aneurysm and acute aortic dissection remains elusive. We sought to identify a novel aortic protein kinase that can be pharmacologically targeted to mit...

Nitro-oleic acid (NO2-OA) reduces thoracic aortic aneurysm progression in a mouse model...
https://doi.org/10.1093/cvr/cvab256
Cardiovascular Research; Nettersheim FS, Lemties J et. al.

Jul 30th, 2021 - Marfan syndrome (MFS) is a connective tissue disorder caused by mutations in the Fibrillin-1 gene. It is associated with formation of thoracic aortic aneurysms that can potentially be a life-threatening condition due to aortic rupture or dissectio...

Integrative analysis of genomic variants reveals new associations of candidate haploins...
https://doi.org/10.1371/journal.pgen.1009679
PLoS Genetics; Audain E, Wilsdon A et. al.

Jul 30th, 2021 - Numerous genetic studies have established a role for rare genomic variants in Congenital Heart Disease (CHD) at the copy number variation (CNV) and de novo variant (DNV) level. To identify novel haploinsufficient CHD disease genes, we performed an...

In-depth bioinformatic study of the cadherin 5 interactome in patients with thoracic ao...
https://doi.org/10.1093/ejcts/ezab338
European Journal of Cardio-thoracic Surgery : Official Jo... Magouliotis DE, Fergadi MP et. al.

Jul 23rd, 2021 - Thoracic aortic aneurysm (TAA) is characterized by the dilation of the aorta and is associated with poor prognosis if not diagnosed and treated early. In this context, the identification of biomarkers regarding the TAA diagnosis, monitoring and pr...

Association of diameter and wall stresses of tricuspid aortic valve ascending thoracic ...
https://doi.org/10.1016/j.jtcvs.2021.05.049
The Journal of Thoracic and Cardiovascular Surgery; Gomez A, Wang Z et. al.

Jul 20th, 2021 - Ascending thoracic aortic aneurysms carry a risk of acute type A dissection. Elective repair guidelines are designed around size thresholds, but the 1-dimensional parameter of maximum diameter cannot predict acute events in small aneurysms. Biomec...

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Guidelines  3 results

Society for Vascular Surgery clinical practice guidelines of thoracic endovascular aort...
https://doi.org/10.1016/j.jvs.2020.05.076
Journal of Vascular Surgery; Upchurch GR, Escobar GA et. al.

Jul 7th, 2020 - Thoracic aortic diseases, including disease of the descending thoracic aorta (DTA), are significant causes of death in the United States. Open repair of the DTA is a physiologically impactful operation with relatively high rates of mortality, para...

ACR Appropriateness Criteria® Suspected Thoracic Aortic Aneurysm.
https://doi.org/10.1016/j.jacr.2018.03.031
Journal of the American College of Radiology : JACR; , Bennett SJ et. al.

May 5th, 2018 - Although the incidence of thoracic aortic aneurysm is on the rise, initial imaging diagnosis can present a challenge for many clinicians. Providers are faced with many imaging choices as part of the initial workup. Considering level of invasivenes...

A Practical Guide to Clinical Management of Thoracic Aortic Disease.
https://doi.org/10.1016/j.cjca.2015.10.020
The Canadian Journal of Cardiology; Bradley TJ, Alvarez NA et. al.

Jan 3rd, 2016 - Physicians and surgeons faced with patients with thoracic aortic disease (TAD) need to determine the underlying diagnosis to facilitate decisions regarding appropriate investigations as well as which other specialists to involve, when to start med...

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Clinicaltrials.gov  17 results

Zenith® TX2® Low Profile TAA Endovascular Graft
https://clinicaltrials.gov/ct2/show/NCT02471781

Jan 18th, 2020 - The Zenith TX2 Low Profile TAA Endovascular Graft extended study is to collect confirmatory safety and effectiveness data. The Zenith TX2 Low Profile TAA Endovascular Graft is indicated for the treatment of patients with a descending thoracic aort...

Physician-Sponsored IDE for the Talent Endoluminal Stent Graft System for the Treatment of Thoracic Lesions
https://clinicaltrials.gov/ct2/show/NCT00597870

Oct 24th, 2018 - The endovascular method consists of the insertion of catheters (vinyl tubes) into both groin arteries. These catheters then allow positioning of artificial tubes or stent graft(s) into the diseased blood vessel without the need for major surgery w...

Prehabilitation for Aortic Repair Patients
https://clinicaltrials.gov/ct2/show/NCT02767518

Sep 10th, 2018 - Patients undergoing elective repair of their thoracic aortic aneurysm will be randomized to a "prehabilitation" program prior to their surgery or to usual care. The prehabilitation program is self-directed program designed to improve health and qu...

Valiant Evo US Clinical Trial
https://clinicaltrials.gov/ct2/show/NCT02652949

Aug 31st, 2018 - The purpose of the Valiant Evo US Clinical Trial is to demonstrate the safety and effectiveness of the Valiant Evo Thoracic Stent Graft System in subjects with a descending thoracic aortic aneurysm (DTAA) who are candidates for endovascular repair.

Pathogenetic Basis of Aortopathy and Aortic Valve Disease
https://clinicaltrials.gov/ct2/show/NCT03440697

Aug 8th, 2018 - Thoracic aortic aneurysm (TAA) is a type of aortopathy describing dilation of the proximal aortic dimensions including the aortic root, which is a risk factor for aortic dissection and sudden cardiac death. TAA and other forms of aortopathy (e.g. ...

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News  16 results

Respiratory effects may account for worse survival in women undergoing DTA and TAAA repair
https://www.mdedge.com/surgery/article/200917/aneurysms/respiratory-effects-may-account-worse-survival-women-undergoing-dta?channel=39313
Mark S. Lesney

May 14th, 2019 - Women undergoing open descending thoracic aortic aneurysm (DTA) and open thoracoabdominal aortic aneurysm (TAAA) repair are not at greater risk for operative mortality than their male counterparts. However, they are at significantly greater risk f.

Superior Survival With TEVAR vs Open Aortic Aneurysm Repair
https://www.medscape.com/viewarticle/909379

Feb 21st, 2019 - Thoracic endovascular aortic repair (TEVAR) confers a survival rate superior to that of open surgical repair of intact descending thoracic aortic aneurysms, a new study suggests. A team of investigators from the Department of Cardiothoracic Surger...

Aortic aneurysm: Fluoroquinolones, genetic counseling
https://www.mdedge.com/ccjm/article/173577/cardiology/aortic-aneurysm-fluoroquinolones-genetic-counseling?channel=312
Mark R. Goldstein, MD, FACP, Luca Mascitelli, MD

Sep 4th, 2018 - To the Editor: We read with interest the article by Cikach et al on thoracic aortic aneurysm. 1 For medical management of this condition, the authors emphasized controlling blood pressure and heart rate and also avoiding isometric exercises and he.

New Clinical Practice Guidelines, August 2018 Edition
https://www.medscape.com/viewarticle/900291_18

Aug 9th, 2018 - Vascular Surgery Arterial Procedures Society for Vascular Surgery (7/2018) After carotid endarterectomy (CEA) or carotid artery stenting (CAS), recommend surveillance with duplex ultrasound (DUS) at baseline and every 6 months for 2 years and annu...

Thoracic aortic aneurysm: How to counsel, when to refer
https://www.mdedge.com/ccjm/article/166717/cardiology/thoracic-aortic-aneurysm-how-counsel-when-refer?channel=312
Frank Cikach, MD, Milind Y. Desai, MD, FACC, FAHA, FESC et. al.

Jun 1st, 2018 - Thoracic aortic aneurysm (TAA) needs to be detected, monitored, and managed in a timely manner to prevent a serious consequence such as acute dissection or rupture. But only about 5% of patients experience symptoms before an acute event occurs, an.

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Patient Education  11 results see all →