ALLMedicine™ Thoracic Aortic Aneurysm Center

Nov 21st, 2022 - Patients with a bicuspid aortic valve have an extreme high risk to develop a thoracic aortic aneurysm and dissection (TAAD). TAADs form a leading cause of death worldwide, with the majority of deaths being preventable if individuals at risk are id...

Nov 18th, 2022 - Primary infected aortic aneurysms are life-threatening if not treated promptly, but still possess a high mortality rate following open repair. The goal of treatment is to prevent rupture and clear infection. An endovascular approach is accepted as...

Nov 12th, 2022 - Phospholipase Cε (PLCε) is a phospholipase C isoform with a wide range of physiologic functions. It has been implicated in aortic valve disorders but its role in frequently associated aortic disease remains unclear. To determine the role of PLCε i...

Nov 7th, 2022 - Thoracic aortic aneurysm and dissection (TAAD) is caused by the apoptosis and phenotypic transformation of vascular smooth muscle cells (VSMCs). The dysfunction of VSMCs affects their secretion of chemokines such as monocyte chemoattractant protei...

Nov 3rd, 2022 - A gentleman in his late 30s presented with a history of evening rise of temperature and generalised malaise of 1-week duration. He had associated upper back pain with tingling and numbness of both lower limbs. An unexplained episode of hypotension...

Jul 7th, 2020 - Thoracic aortic diseases, including disease of the descending thoracic aorta (DTA), are significant causes of death in the United States. Open repair of the DTA is a physiologically impactful operation with relatively high rates of mortality, para...

May 5th, 2018 - Although the incidence of thoracic aortic aneurysm is on the rise, initial imaging diagnosis can present a challenge for many clinicians. Providers are faced with many imaging choices as part of the initial workup. Considering level of invasivenes...

Jan 3rd, 2016 - Physicians and surgeons faced with patients with thoracic aortic disease (TAD) need to determine the underlying diagnosis to facilitate decisions regarding appropriate investigations as well as which other specialists to involve, when to start med...

Aug 3rd, 2022 - The endovascular method consists of the insertion of catheters (vinyl tubes) into both groin arteries. These catheters then allow positioning of artificial tubes or stent graft(s) into the diseased blood vessel without the need for major surgery w...

Jun 6th, 2022 - Patient Population and Clinical Measurements: The Frankel Cardiovascular Center at the University of Michigan Health System (UMHS) is a regional center with expertise in managing a large variety of aortic diseases. Only adult patients (age between...

Jun 3rd, 2022 - Thoracic aneurysm is a silent disease with a potential mid-term high risk of death or major complications. Few data are available on the real incidence of major complications in case of small and moderate thoracic aneurysm. Different factors are s...

Apr 27th, 2022 - All patients referred electively to a participating investigator for the evaluation of their ascending aortic aneurysm will be screened for study eligibility. Patients between the age of 18 and 79 with an asymptomatic ascending aortic aneurysm bet...

Jan 24th, 2022 - Patients undergoing elective repair of their thoracic aortic aneurysm will be randomized to a "prehabilitation" program prior to their surgery or to usual care. The prehabilitation program is self-directed program designed to improve health and qu...

May 12th, 2021 - An 88-year-old male veteran with a medical history of chronic obstructive pulmonary disease (COPD) on home oxygen, chronic alcohol use, squamous cell carcinoma of the lung status after left upper lobectomy, and a 5. 7 cm thoracic aortic aneurysm wa.

Apr 12th, 2021 - For the first time, fluoroquinolone exposure was tied to aortic complications in patients with established aortic disease in a large study. In the cohort study from Taiwan, people with an existing aortic dissection (AD) or aortic aneurysm (AA) wer...

Jan 6th, 2021 - The link between fluoroquinolone antibiotics and aortic aneurysm (AA) was further strengthened by analysis of a U.S. commercial claims database. Incidence of AA formation or dissection reached 7.5 per 10,000 prescription fills for fluoroquinolones...

May 14th, 2019 - Women undergoing open descending thoracic aortic aneurysm (DTA) and open thoracoabdominal aortic aneurysm (TAAA) repair are not at greater risk for operative mortality than their male counterparts. However, they are at significantly greater risk f.

May 14th, 2019 - Women undergoing open descending thoracic aortic aneurysm (DTA) and open thoracoabdominal aortic aneurysm (TAAA) repair are not at greater risk for operative mortality than their male counterparts. However, they are at significantly greater risk f.