ALLMedicine™ Thrombosis Center

Dec 6th, 2022 - Intestinal failure (IF) is a rare disease that requires ongoing intravenous supplementation to sustain growth and health. Advancements in parenteral nutrition (PN) and central venous access in the 1960s and 1970s transformed a life-limiting diseas...

Dec 6th, 2022 - Superior vena cava (SVC) syndrome refers to the clinical manifestations of cerebral venous hypertension secondary to obstruction of the SVC and/or the innominate veins. The most common cause of SVC syndrome is malignancy like small cell lung cance...

Dec 6th, 2022 - Variants of the junctional cadherin 5 associated (JCAD) locus associate with acute coronary syndromes. JCAD promotes experimental atherosclerosis through the large tumor suppressor kinase 2 (LATS2)/Hippo pathway. This study investigates the role o...

Dec 6th, 2022 - Pseudoaneurysms (PSA) are one of the most common complications after arterial punctures. This retrospective study examined whether platelet aggregation inhibitors (APT) or anticoagulants (AC) lower the success rates of PSA treatment. A total of 46...

Dec 6th, 2022 - To explore the clinical and radiological effects of the free vascularized iliac bone flap (FVIBF) based on deep iliac circumflex vessels for Association Research Circulation Osseous (ARCO) stage 3 traumatic osteonecrosis of the femoral head (TONFH...

Nov 28th, 2022 - Pulmonary embolism (PE) remains a common and important clinical condition that cannot be accurately diagnosed on the basis of signs, symptoms, and history alone. The diagnosis of PE has been facilitated by technical advancements and multidetector ...

Mar 19th, 2022 - The prevention and management of bleeding and thrombosis in patients with cirrhosis poses several difficult clinical questions. These Clinical Practice Guidelines have been developed to provide practical guidance on debated topics, including curre...

Nov 3rd, 2021 - COVID-19-related acute illness is associated with an increased risk of venous thromboembolism (VTE). These evidence-based guidelines of the American Society of Hematology (ASH) are intended to support patients, clinicians, and other health care pr...

Sep 24th, 2021 - Hydroxychloroquine is the most widely prescribed intracellular anti-infective for human SARS-CoV-2 infection and COVID-19 syndrome. There have been 296 studies, 220 of which are peer reviewed, 246 comparing treatment and control groups [1]. This a...

Sep 3rd, 2021 - COVID-19-related critical illness is associated with an increased risk of venous thromboembolism (VTE). These evidence-based guidelines of the American Society of Hematology (ASH) are intended to support patients, clinicians, and other health care...

Oct 14th, 2022 - The non-interventional study (NIS) CICERO will collect real-world data to explore acalabrutinib (+/- obinutuzumab) in adult CLL patients (irrespective of treatment line) who receive co-medication with DOACs. The primary focus of the study is to in...

Oct 14th, 2022 - A patent foramen ovale (PFO) is present in ~30% of the general population. The PFO has historically been considered to be trivial. However, recent work by the investigator's group and others has identified that, compared to individuals without a P...

Oct 14th, 2022 - To provide more information on safety profile of VAXZEVRIA in Japanese subjects, specific drug use result study in subjects with underling disease at higher risk of worsening COVID-19 is planned as an additional pharmacovigilance plan. The present...

Oct 13th, 2022 - D-dimer, a fibrin degradation product generated as a result of plasmin mediated clot dissolution processes, is an indicator of recent clot formation and subsequent fibrinolysis. Analysis of D-dimer concentration is employed in the diagnosis of dee...

Oct 13th, 2022 - The ULTREC research project is designed to assess the safety of a negative strategy relying on Colour Doppler Ultrasound (CDUS) for excluding the diagnosis of a new thrombosis. The ULTREC project does not take into account the validity of the CDUS...

Dec 6th, 2022 - Vaccination against the flu showed mixed results for cardiovascular prevention in a large international trial. (The Lancet Global Health) Dietary supplements with the strongest evidence for cardiometabolic benefits: omega-3 fatty acids, folic acid...

Nov 22nd, 2022 - PHILADELPHIA — A draft update of criteria for classifying antiphospholipid syndrome (APS) incorporates a much broader spectrum of disease signs and symptoms, such as kidney disease and more variables for pregnancy, and meets a higher level of spec...

Nov 18th, 2022 - The study covered in this summary was published in Research Square as a preprint and has not yet been peer reviewed. Key Takeaways Endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) may be a less invasive alternative to resection of pa...

Nov 10th, 2022 - The 6000-patient BRIGHT-4 trial from China is prompting a rethink on bivalirudin in cath labs around the world and whether it should be the first-choice anticoagulant in primary percutaneous coronary intervention (PCI) for ST-segment elevation myo...

Nov 10th, 2022 - A new US randomized trial has failed to show benefit of a 35-day course of oral anticoagulation with rivaroxaban for the prevention of thrombotic events in outpatients with symptomatic COVID-19. The PREVENT-HD trial was presented at the American H...