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Efficacy and Safety of Low-Dose Colchicine after Myocardial Infarction
https://www.nejm.org/doi/full/10.1056/NEJMoa1912388?query=featured_home
New England Journal of Medicine; Tardif JC et al

Nov 16th, 2019 - Experimental and clinical evidence support the role of inflammation in atherosclerosis and its complications. Colchicine is an orally administered, potent antiinflammatory medication that is indicated for the treatment of gout and pericarditis.

Subclinical and Device-Detected Atrial Fibrillation: Pondering the Knowledge Gap: A Scientific Statement From the American Heart Association
https://www.ahajournals.org/doi/10.1161/CIR.0000000000000740
Circulation Peter A. Noseworthy, et al.

Nov 14th, 2019 - The widespread use of cardiac implantable electronic devices and wearable monitors has led to the detection of subclinical atrial fibrillation in a substantial proportion of patients. There is evidence that these asymptomatic arrhythmias are associated with increased risk of stroke. Thus, detection of subclinical atrial fibrillation may offer an opportunity to reduce stroke risk by initiating a...

Marijuana Use Linked to Stroke, Arrhythmia in Young People
https://www.medscape.com/viewarticle/921116
Medscape

Nov 13th, 2019 - Use of marijuana is linked to a higher risk of stroke and hospitalization for cardiac arrhythmia in young people, two new studies suggest.

2019 AHA/ACC Clinical Performance and Quality Measures for Adults With High Blood Pressure: A Report of the American College of Cardiology/American Heart Association Task Force on Performance Measures
https://www.ahajournals.org/doi/10.1161/HCQ.0000000000000057
Circulation: Cardiovascular Quality and Outcomes; Casey E, et al.

Nov 12th, 2019 - In 2018, the Task Force convened the writing committee to begin the process of revising the existing performance measures set for hypertension that had been released in 2011.3 The writing committee also was charged with the task of developing new measures to evaluate the care of patients in accordance with the 2017 Hypertension Clinical Practice Guidelines.4 The writing committee developed a...

Renin-Angiotensin System Inhibitors vs. Other Antihypertensive Drug Classes for Hypertension
https://www.aafp.org/afp/2019/1101/p540.html
American Family Physician; JEFFREY C. LEGGIT, MD

Nov 5th, 2019 - RAS inhibitors have been widely prescribed to treat hypertension; however, it remains unclear whether they are superior to other antihypertensive drugs in terms of clinically relevant outcomes for primary hypertension.

Comprehensive comparative effectiveness and safety of first-line antihypertensive drug classes: a systematic, multinational, large-scale analysis
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(19)32317-7/fulltext

Oct 23rd, 2019 - Uncertainty remains about the optimal monotherapy for hypertension, with current guidelines recommending any primary agent among the first-line drug classes thiazide or thiazide-like diuretics, angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, dihydropyridine calcium channel blockers, and non-dihydropyridine calcium channel blockers, in the absence of comorbid indications...

Relief and Prevention of Congestion in Heart Failure Enhance Quality and Length of Life
https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.119.042660
Circulation Drazner, M. et. al.

Oct 20th, 2019 - This article is a commentary on the following Prognostic Implications of Congestion on Physical Examination Among Contemporary Patients With Heart Failure and Reduced Ejection Fraction

Farxiga approved in the US to reduce the risk of hospitalisation for heart failure in patients with type-2 diabetes
https://www.astrazeneca.com/content/astraz/media-centre/press-releases/2019/farxiga-approved-in-the-us-to-reduce-the-risk-of-hospitalisation-for-heart-failure-in-patients-with-type-2-diabetes-21102019.html

Oct 20th, 2019 - AstraZeneca today announced that the US Food and Drug Administration (FDA) has approved Farxiga (dapagliflozin) to reduce the risk of hospitalisation for heart failure (hHF) in adults with type-2 diabetes (T2D) and established cardiovascular disease (CVD) or multiple cardiovascular (CV) risk factors.

TCT 2019: Top Interventional Takeaways
https://www.acc.org/latest-in-cardiology/articles/2019/10/06/24/42/tct-2019-top-interventional-takeaways

Oct 17th, 2019 - TCT 2019 in San Francisco has left us with a few trials that potentially may change our interventional practice. The COMPLETE study is now complete! To refresh your memory, the COMPLETE trial was presented at ESC Congress 2019, one month before TCT, and studied patients presented with STEMI and multivessel disease. At a median of three-years follow-up, complete revascularization was superior to...

Association of Cardiovascular Disease With Premature Mortality in the United States
https://jamanetwork.com/journals/jamacardiology/fullarticle/2752889
JAMA Cardiology; Chen, Y. et. al.

Oct 15th, 2019 - Question How have the trends in premature mortality from cardiovascular disease (CVD) changed in the United States during 2000 to 2015 by demographics and county-level factors, including education, rurality, and the prevalence of smoking, obesity, and diabetes? Findings In this study, CVD mortality rates increased significantly among American Indian/Alaska Native individuals age 25 to 49 y...

Statins for primary prevention of cardiovascular disease
https://www.bmj.com/content/367/bmj.l5674/article-info
BMJ Byrne, P. et. al.

Oct 15th, 2019 - Statins are now the most commonly used drug in the UK and one of the most commonly used medicines in the world.12 Although prices have fallen since their patents expired, statins account for substantial drug expenditure in a context of often overstretched healthcare budgets, with estimated global sales approaching $1tn by 2020.3 Use of statins in people with established cardiovascular disease i...

The 2019 ESC Guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD: New features and the ‘Ten Commandments’ of the 2019 Guidelines are discussed...
https://academic.oup.com/eurheartj/article/40/39/3215/5586545
European Heart Journal; Grant, P. et. al.

Oct 13th, 2019 - The prevalence of diabetes continues to increase, with 60 million thought to have diabetes in Europe in 2017 and predictions of more than 600 million individuals with diabetes worldwide by 2045. These numbers carry a huge burden of morbidity and mortality with a high prevalence of microvascular disease affecting the eyes, nerves, and kidneys and macrovascular disease leading to CV, cerebrovascu...

Longitudinal Associations Between Income Changes and Incident Cardiovascular Disease
https://jamanetwork.com/journals/jamacardiology/article-abstract/2752544
JAMA Cardiology; Wang, S. et. al.

Oct 8th, 2019 - Question What is the association between bidirectional income change and cardiovascular disease? Findings In this cohort study of middle-aged, community-dwelling adults, a more than 50% income drop was significantly associated with higher risk of incident cardiovascular disease, while a more than 50% income rise was significantly associated with lower risk of incident cardiovascular diseas...

Dog Ownership and Survival
https://www.ahajournals.org/doi/10.1161/CIRCOUTCOMES.119.005554
Circulation Kramer, C. et. al.

Oct 7th, 2019 - Dog ownership has been associated with decreased cardiovascular risk. Recent reports have suggested an association of dog companionship with lower blood pressure levels, improved lipid profile, and diminished sympathetic responses to stress. However, it is unclear if dog ownership is associated with improved survival as previous studies have yielded inconsistent results. Thus, we performed a sy...

A Clinician's Guide to Healthy Eating for Cardiovascular Disease Prevention
https://www.acc.org/latest-in-cardiology/articles/2019/10/08/13/20/a-clinicians-guide-to-healthy-eating-for-cvd-prevention

Oct 7th, 2019 - The recently released 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease has given clinicians a comprehensive, evidence-based resource to inform management of patients at increased risk of atherosclerotic cardiovascular disease. In addition to guidance on risk stratification and medication prescribing, the Prevention Guideline stresses the importance of lifestyle interve...

Statin Use in Primary Prevention of ASCVD According to 5 Guidelines
https://www.acc.org/latest-in-cardiology/journal-scans/2019/10/08/11/49/statin-use-in-primary-prevention-of-atherosclerotic

Oct 7th, 2019 - Is there a difference in the sensitivity, specificity, and estimated number needed to treat (NNT10) with a statin to prevent one atherosclerotic cardiovascular disease (ASCVD) event in 10 years by criteria from five of the major guidelines?

Spironolactone With Patiromer in the Treatment of Resistant Hypertension in Chronic Kidney Disease - AMBER
https://www.acc.org/latest-in-cardiology/clinical-trials/2019/10/08/14/26/amber

Oct 7th, 2019 - The AMBER trial showed that the potassium binder patiromer was effective at allowing more patients to remain on spironolactone.

Sleeping less than six hours and heart disease, stroke – deadly combo
https://newsroom.heart.org/news/sleeping-less-than-six-hours-and-heart-disease-stroke-deadly-combo

Oct 1st, 2019 - Middle-aged adults with high blood pressure, Type 2 diabetes, heart disease or stroke could be at increased risk for cancer and early death when sleeping less than 6 hours per day.

Preventive Cardiology as a Subspecialty of Cardiovascular Medicine
http://www.onlinejacc.org/content/74/15/1926?_ga=2.47888103.1317319445.1570642054-675541502.1568116402
Journal of the American College of Cardiology; Shapiro, M. et. al.

Oct 1st, 2019 - Although significant progress has been made to reduce the global burden of cardiovascular disease, efforts have focused primarily on treatment of manifest disease rather than on prevention of events. An enormous opportunity exists to transition focus from intervention to providing equal attention to prevention of cardiovascular disease. The nascent specialty of “preventive cardiology” is emergi...

Anticoagulation: Updated Guidelines for Outpatient Management
https://www.aafp.org/afp/2019/1001/p426.html
American Family Physician;

Sep 30th, 2019 - Anticoagulation therapy is recommended for preventing, treating, and reducing the recurrence of venous thromboembolism, and preventing stroke in persons with atrial fibrillation. Direct oral anticoagulants are first-line agents for eligible patients for treating venous thromboembolism and preventing stroke in those with nonvalvular atrial fibrillation. Vitamin K antagonists are recommended for ...