About 39,850 results
Heart Failure Society of America Meeting

Sep 12th, 2019 - HFSA's Annual Scientific Meeting is intended for physicians, nurses, nurse practitioners, pharmacists, scientists, and health care professionals .

Effects of Helicobacter pylori treatment and vitamin and garlic supplementation on gastric cancer incidence and mortality: follow-up of a randomized intervention trial
The BMJ;

Sep 10th, 2019 - Objective To assess the effects of Helicobacter pylori treatment, vitamin supplementation, and garlic supplementation in the prevention of gastric cancer. Design Blinded randomized placebo controlled trial. Setting Linqu County, Shandong province, China. Participants 3365 residents of a high risk region for gastric cancer. 2258 participants seropositive for antibodies to H pylori were ...

Menopausal Estrogen-Alone Therapy and Health Outcomes in Women With and Without Bilateral Oophorectomy: A Randomized Trial
Annals of Internal Medicine;

Sep 9th, 2019 - Background: Whether health outcomes of menopausal estrogen therapy differ between women with and without bilateral salpingo-oophorectomy (BSO) is unknown. Objective: To examine estrogen therapy outcomes by BSO status, with additional stratification by 10-year age groups. Design: Subgroup analyses of the randomized Women's Health Initiative Estrogen-Alone Trial. (ClinicalTrials.gov: NCT...

Hypertension Scientific Sessions 2019

Sep 6th, 2019 - Hypertension Scientific Sessions 2019, Sept. 5-8, 2019 in New Orleans, LA, explores the latest clinical and basic research on hypertension science.

Hypertension 2019 Scientific Sessions -Final Program

Sep 6th, 2019 - Sponsored and organized by the Council on Hypertension in collaboration Sponsored and organized by the Council on Hypertension in collaboration with the Council on the Kidney in Cardiovascular Disease with the Council on the Kidney in Cardiovascular Disease.

Modifiable risk factors, cardiovascular disease, and mortality in 155 722 individuals from 21 high-income, middle-income, and low-income countries (PURE): a prospective cohort study
The Lancet; Yusuf, S. et. al.

Sep 2nd, 2019 - Global estimates of the effect of common modifiable risk factors on cardiovascular disease and mortality are largely based on data from separate studies, using different methodologies. The Prospective Urban Rural Epidemiology (PURE) study overcomes these limitations by using similar methods to prospectively measure the effect of modifiable risk factors on cardiovascular disease and mortality ac...

Ticagrelor or Prasugrel in Patients with Acute Coronary Syndromes
The New England Journal of Medicine; Schüpke, S. et. al.

Aug 31st, 2019 - BACKGROUND The relative merits of ticagrelor as compared with prasugrel in patients with acute coronary syndromes for whom invasive evaluation is planned are uncertain. METHODS In this multicenter, randomized, open-label trial, we randomly assigned patients who presented with acute coronary syndromes and for whom invasive evaluation was planned to receive either ticagrelor or prasugrel. Th...

Effects of Serelaxin in Patients with Acute Heart Failure
The New England Journal of Medicine; Metra, M. et. al.

Aug 21st, 2019 - BACKGROUND Serelaxin is a recombinant form of human relaxin-2, a vasodilator hormone that contributes to cardiovascular and renal adaptations during pregnancy. Previous studies have suggested that treatment with serelaxin may result in relief of symptoms and in better outcomes in patients with acute heart failure. METHODS In this multicenter, double-blind, placebo-controlled, event-driven ...

Improving Access to Guideline-Based Coronary Artery Calcium Testing for Cardiovascular Disease Prevention
JAMA Cardiology;

Aug 20th, 2019 - With the publication of the 2018 Cholesterol Clinical Practice Guidelines and the 2019 American College of Cardiology/American Heart Association Guideline on the Primary Prevention of Cardiovascular Disease comes a greater focus on shared decision-making regarding the institution of pharmacologic therapy for patients at increased risk of experiencing future cardiovascular events. In particular,...

Associations between blood pressure across adulthood and late-life brain structure and pathology in the neuroscience substudy of the 1946 British birth cohort (Insight 46): an epidemiological study
The Lancet Neurology;

Aug 19th, 2019 - Midlife hypertension confers increased risk for cognitive impairment in late life. The sensitive period for risk exposure and extent that risk is mediated through amyloid or vascular-related mechanisms are poorly understood. We aimed to identify if, and when, blood pressure or change in blood pressure during adulthood were associated with late-life brain structure, pathology, and cognition.

Insomnia tied to higher risk of heart disease and stroke

Aug 18th, 2019 - People suffering from insomnia may have an increased risk of coronary artery disease, heart failure and stroke, according to new research in the American Heart Association’s journal Circulation. Previous observational studies have found an association between insomnia, which affects up to 30% of the general population, and an increased risk of developing heart disease and stroke. These obse...

Intensive blood pressure management may preserve brain health

Aug 13th, 2019 - Numerous large, cohort studies have linked midlife hypertension to mild cognitive impairment and dementia later on. Some of these studies found a higher risk of lesions in the brain's white matter in older age among people with high blood pressure in their 50s. The white matter of the brain consists of bundles of axons, which are the thin elongations of neurons. White matter is "white" due to m...

Should Adults With Prediabetes Be Prescribed Metformin To Prevent Diabetes Mellitus? No: Evidence Does Not Show Improvements in Patient-Oriented Outcomes
American Family Physician; Brown, S.

Aug 1st, 2019 - Prediabetes is not a disease. It is a risk factor for a disease (diabetes mellitus). Most people with so-called prediabetes will not develop diabetes within five years.1 The American Diabetes Association (ADA) definition of prediabetes now includes a threshold value in fasting glucose (100 to 125 mg per dL [5.5 to 6.9 mmol per L]), two-hour glucose tolerance test (140 to 199 mg per dL [7.8 to 1...

Autopsies reveal how meth hurts the heart

Jul 31st, 2019 - Use of the illegal stimulant methamphetamine causes build-up of tough protein fibers in heart muscle, which may help explain the development of enlarged hearts and heart failure in users, according to preliminary research presented at the American Heart Association’s Basic Cardiovascular Sciences 2019 Scientific Sessions.

Updates to the 2019 Standards of Medical Care in Diabetes Issued Today by the American Diabetes Association

Jul 30th, 2019 - The American Diabetes Association® (ADA) issued important updates to the 2019 Standards of Medical Care in Diabetes (Standards of Care) today, in annotations as the Living Standards of Care, with the changes focusing on new metrics for continuous glucose monitoring (CGM) utilization and new medication options and recommendations for youth and adults with type 2 diabetes. The updates were inform...

Pulse waves measured at the wrist uncover often-missed artery changes in menopausal women

Jul 28th, 2019 - Measuring a menopausal woman’s pulse wave at her wrist can detect circulatory system changes that aren’t evident with blood pressure readings. Menopause’s effect on these radial pulse wave harmonics can help explain why women in menopause are at heightened cardiovascular disease risk.

AHA's "Life's Simple 7" Reduces Heart Failure Risk

Jul 24th, 2019 - The incidence of congestive heart failure (HF) was reduced by 47% in a group of individuals adhering to a combination of healthy lifestyle practices; among individuals who adhered to an “ideal” combination of those practices, HF was reduced by 55%. In a recent study that analyzed the impact of the American Heart Association’s (AHA) Life’s Simple 7 (LS7) healthy behaviors on HF risk reduction, t...

Intensive vs Standard Treatment of Hyperglycemia and Functional Outcome in Patients With Acute Ischemic Stroke

Jul 22nd, 2019 - Question Does intensive glucose control improve functional outcome in patients with hyperglycemic acute ischemic stroke? Findings This randomized clinical trial included 1151 adults who received either intensive treatment of hyperglycemia (target blood glucose concentration of 80-130 mg/dL) or standard treatment of hyperglycemia (target glucose concentration of 80-179 mg/dL). The proportio...

Recent Research on the Health Benefits of Blueberries and Their Anthocyanins
Advances in Nutrition; Kalt, W. et. al.

Jul 21st, 2019 - Awareness of the human health benefits of blueberries is underpinned by a growing body of positive scientific evidence from human observational and clinical research, plus mechanistic research using animal and in vitro models. Blueberries contain a large number of phytochemicals, including abundant anthocyanin pigments. Of their various phytochemicals, anthocyanins probably make the greatest im...