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About 1,025 results

ALLMedicine™ Malignant Hyperthermia Center

Research & Reviews  368 results

Anaesthetic management of a parturient patient with a malignant hyperthermia partner.
https://doi.org/10.1136/bcr-2021-247953
BMJ Case Reports; Dolan R, Corcoran F

Apr 10th, 2022 - Malignant hyperthermia (MH) is a rare but deleterious anaesthetic emergency that has an autosomal dominant inheritance. Successful management of the MH-susceptible fetus hinges on early suspicion and preparation. This case highlights the importanc...

Referral Indications for Malignant Hyperthermia Susceptibility Diagnostics in Patients ...
https://doi.org/10.1097/ALN.0000000000004199
Anesthesiology van den Bersselaar LR, Hellblom A et. al.

Mar 15th, 2022 - The introduction of next-generation sequencing into the diagnosis of neuromuscular disorders has resulted in an increased number of newly identified RYR1 variants. The hypothesis was that there is an increased referral of patients to malignant hyp...

Anesthetic Management of an Adult With Hyperekplexia Undergoing a Laparoscopic Colectom...
https://doi.org/10.1213/XAA.0000000000001571
A&A Practice; Chang BA, Bernstein KR

Mar 8th, 2022 - Hyperekplexia is a rare genetic disorder characterized by an exaggerated startle response to innocuous stimuli. There are several case reports documenting the administration of general anesthesia to infants and children with hyperekplexia and 1 ca...

Population at Risk of Malignant Hyperthermia: Ambispective Cohort.
https://clinicaltrials.gov/ct2/show/NCT04287556

Jan 13th, 2022 - Malignant hyperthermia (MH) is a pharmacogenetic disease that manifests itself as a hypermetabolic response of skeletal musculature, in genetically susceptible patients, with the inhalation of volatile halogenated anesthetics, depolarizing neuromu...

Age-Specific Clinical Features of Pediatric Malignant Hyperthermia: A Review of 187 Cas...
https://doi.org/10.1213/ANE.0000000000005837
Anesthesia and Analgesia; Otsuki S, Miyoshi H et. al.

Dec 29th, 2021 - Malignant hyperthermia (MH) is an inherited muscle disorder induced by volatile anesthetics and depolarizing muscle relaxants. While the incidence of MH is high in young, there are few reports on the clinical features of pediatric MH. In this stud...

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Guidelines  4 results

Consensus guidelines on perioperative management of malignant hyperthermia suspected or...
https://doi.org/10.1016/j.bja.2020.09.029
British Journal of Anaesthesia; Rüffert H, Bastian B et. al.

Nov 3rd, 2020 - Malignant hyperthermia is a potentially fatal condition, in which genetically predisposed individuals develop a hypermetabolic reaction to potent inhalation anaesthetics or succinylcholine. Because of the rarity of malignant hyperthermia and ethic...

Availability of dantrolene for the management of malignant hyperthermia crises: Europea...
https://doi.org/10.1016/j.bja.2020.04.089
British Journal of Anaesthesia; Glahn KPE, Bendixen D et. al.

Jun 28th, 2020 - Faced with a malignant hyperthermia crisis, the immediate access to sufficient dantrolene is essential to achieve the best possible outcome for the patient. However, malignant hyperthermia crises are rare, and there may be administrative pressures...

Malignant Hyperthermia-Susceptible Adult Patient and Ambulatory Surgery Center: Society...
https://doi.org/10.1213/ANE.0000000000004257
Anesthesia and Analgesia; Urman RD, Rajan N et. al.

Jun 6th, 2019 - This document represents a joint effort of the Society for Ambulatory Anesthesia (SAMBA) and the Ambulatory Surgical Care Committee of the American Society of Anesthesiologists (ASA) concerning the safe anesthetic care of adult malignant hyperther...

Special article: Creation of a guide for the transfer of care of the malignant hyperthe...
https://doi.org/10.1213/ANE.0b013e3182373b4a
Anesthesia and Analgesia; Larach MG, Dirksen SJ et. al.

Nov 5th, 2011 - Volatile anesthetics and/or succinylcholine may trigger a potentially lethal malignant hyperthermia (MH) event requiring critical care crisis management. If the MH triggering anesthetic is given in an ambulatory surgical center (ASC), then the pat...

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Drugs  13 results see all →

Clinicaltrials.gov  9 results

Population at Risk of Malignant Hyperthermia: Ambispective Cohort.
https://clinicaltrials.gov/ct2/show/NCT04287556

Jan 13th, 2022 - Malignant hyperthermia (MH) is a pharmacogenetic disease that manifests itself as a hypermetabolic response of skeletal musculature, in genetically susceptible patients, with the inhalation of volatile halogenated anesthetics, depolarizing neuromu...

Gene Mutation Spectrum of Malignant Hyperthermia in China
https://clinicaltrials.gov/ct2/show/NCT04474860

Nov 10th, 2021 - When MH cases or suspected cases occur in China, anesthesiologists can seek help through malignant hyperthermia emergency rescue WeChat group in which experts from all over the country will give therapy instructions. Afterwards, the responsible an...

Comparison of Postoperative QoR-15 Scores Between Desflurane and Remimazolam in Lumbar Fusion Surgery
https://clinicaltrials.gov/ct2/show/NCT04983966

Aug 9th, 2021 - The purpose of the study is to compare the quality of recovery (QoR)-15 scores according to the use of maintenance anesthetics in the lumbar fusion surgery. Total intravenous anesthesia (TIVA) have been known to help reducing risks of postoperativ...

Assessment of Remifentanil for Rapid Sequence Induction and Intubation in Full Stomach Patient Compared to Muscle Relaxant
https://clinicaltrials.gov/ct2/show/NCT03960801

Apr 27th, 2021 - BACKGROUND: Rapid sequence intubation is the reference anaesthetic procedure for patient at risk of pulmonary aspiration of gastric contents (for example emergency procedure, bowel obstruction, obese patients, gastroesophageal reflux …) or difficu...

Antioxidant Therapy in RYR1-Related Congenital Myopathy
https://clinicaltrials.gov/ct2/show/NCT02362425

Dec 24th, 2019 - Although genetic disorders of muscle that present at birth are rare, RYR1-related myopathies comprise the most common non-dystrophic congenital myopathy in the United States, with a prevalence of approximately 1/90,000 people (Amburgey et al, 2011...

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News  13 results

Coronavirus (COVID-19) Update: Daily Roundup May 26, 2020
http://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-daily-roundup-may-26-2020

For Immediate Release: May 26, 2020 The U.S. Food and Drug Administration today announced the following actions taken in its ongoing response effort to the COVID-19 pandemic: The FDA issued an Emergency Use Authorization (EUA) in response to conce...

Coronavirus (COVID-19) Update: December 22, 2020
http://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-december-22-2020

For Immediate Release: December 22, 2020 The U.S. Food and Drug Administration today announced the following actions taken in its ongoing response effort to the COVID-19 pandemic: The FDA has posted translations of the Moderna COVID-19 Vaccine fac...

Coronavirus (COVID-19) Update: Daily Roundup June 17, 2020
http://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-daily-roundup-june-17-2020

For Immediate Release: June 17, 2020 The U.S. Food and Drug Administration today announced the following actions taken in its ongoing response effort to the COVID-19 pandemic: On June 16, 2020, the FDA approved an abbreviated new drug application ...

Coronavirus (COVID-19) Update: Daily Roundup May 19, 2020
http://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-daily-roundup-may-19-2020

For Immediate Release: May 19, 2020 The U.S. Food and Drug Administration today announced the following actions taken in its ongoing response effort to the COVID-19 pandemic: Today, the FDA approved succinylcholine chloride injection USP 200 mg/10...

A 26-Year-Old Woman With Confusion and Hyperthermia
https://reference.medscape.com/viewarticle/876162_4

Feb 24th, 2017 - Besides serotonin syndrome, other differential diagnoses were considered but excluded in this case. Neuroleptic malignant syndrome (NMS) is an idiopathic drug reaction to antipsychotics that has a presentation similar to that of serotonin syndrome...

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Patient Education  3 results see all →