ALLMedicine™ Malignant Hyperthermia Center
Research & Reviews 452 results
https://doi.org/10.1007/s00213-023-06321-x
Psychopharmacology Cameron-Burr KT, Bola RA et. al.
Jan 27th, 2023 - Hyperthermia induced by psychomotor stimulants may cause leakage of the blood-brain barrier, vasogenic edema, and lethality in extreme cases. Current treatments such as whole-body cooling are only symptomatic and a clear need to develop pharmacolo...
https://doi.org/10.1016/j.ejmg.2023.104706
European Journal of Medical Genetics; Lester EB, Larsen MJ et. al.
Jan 21st, 2023 - Disease causing variants in the Ryanodine receptor 1 (RYR1) gene are a common cause for congenital myopathy and for malignant hyperthermia susceptibility. We report a 17 year old boy with congenital muscle weakness progressing to a myasthenia like...
https://doi.org/10.1073/pnas.2117503120
Proceedings of the National Academy of Sciences of the Un... Singh DP, Pearce L et. al.
Jan 18th, 2023 - Resting skeletal muscle generates heat for endothermy in mammals but not amphibians, while both use the same Ca2+-handling proteins and membrane structures to conduct excitation-contraction coupling apart from having different ryanodine receptor (...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9847307
The American Journal of Case Reports; Yeh J, Al Ashi A et. al.
Jan 14th, 2023 - BACKGROUND The purpose of this study is to discuss a patient with a history of conditions, including arthrogryposis, gastroschisis, and malignant hyperthermia, who presented with cecal volvulus requiring urgent surgical intervention. CASE REPORT A...
https://doi.org/10.1213/XAA.0000000000001651
A&A Practice; Fu PH, Ho CN
Jan 5th, 2023 - Malignant hyperthermia (MH) is a rare but life-threatening genetic disorder of the skeletal muscles triggered by inhalation anesthetics or succinylcholine. A 49-year-old female developed symptoms of MH shortly after a lumbar surgery. Despite being...
Guidelines 4 results
https://doi.org/10.1016/j.bja.2020.09.029
British Journal of Anaesthesia; Rüffert H, Bastian B et. al.
Nov 3rd, 2020 - Malignant hyperthermia is a potentially fatal condition, in which genetically predisposed individuals develop a hypermetabolic reaction to potent inhalation anaesthetics or succinylcholine. Because of the rarity of malignant hyperthermia and ethic...
https://doi.org/10.1016/j.bja.2020.04.089
British Journal of Anaesthesia; Glahn KPE, Bendixen D et. al.
Jun 28th, 2020 - Faced with a malignant hyperthermia crisis, the immediate access to sufficient dantrolene is essential to achieve the best possible outcome for the patient. However, malignant hyperthermia crises are rare, and there may be administrative pressures...
https://doi.org/10.1213/ANE.0000000000004257
Anesthesia and Analgesia; Urman RD, Rajan N et. al.
Jun 6th, 2019 - This document represents a joint effort of the Society for Ambulatory Anesthesia (SAMBA) and the Ambulatory Surgical Care Committee of the American Society of Anesthesiologists (ASA) concerning the safe anesthetic care of adult malignant hyperther...
https://doi.org/10.1213/ANE.0b013e3182373b4a
Anesthesia and Analgesia; Larach MG, Dirksen SJ et. al.
Nov 5th, 2011 - Volatile anesthetics and/or succinylcholine may trigger a potentially lethal malignant hyperthermia (MH) event requiring critical care crisis management. If the MH triggering anesthetic is given in an ambulatory surgical center (ASC), then the pat...
Drugs 19 results see all →
Clinicaltrials.gov 34 results
https://clinicaltrials.gov/ct2/show/NCT02561598
Dec 15th, 2022 - The current study will use the combination of electronic medical records and genomic information in samples of persons who have exhibited signs of Malignant Hyperthermia (MH) or have family history or high risk of MH to see if risk factors can be ...
https://clinicaltrials.gov/ct2/show/NCT04983966
Sep 16th, 2022 - The purpose of the study is to compare the quality of recovery (QoR)-15 scores according to the use of maintenance anesthetics in the lumbar fusion surgery. Total intravenous anesthesia (TIVA) have been known to help reducing risks of postoperativ...
https://clinicaltrials.gov/ct2/show/NCT05402839
Jun 2nd, 2022 - This study intends to target patients who underwent surgery under general anesthesia during the study period and developed malignant hyperthermia during or after surgery. Therefore, the total sample size was estimated to be about 50 people based o...
https://clinicaltrials.gov/ct2/show/NCT05036148
Apr 15th, 2022 - We evaluated every referral to the MH centre since 2002 then. IVCT results, clinical data, personal and family history and molecular genetic data, have been recorded in an electronic medical record. Potential MHS patients, probands, were investiga...
https://clinicaltrials.gov/ct2/show/NCT05019222
Mar 31st, 2022 - The purpose of the study is to compare the quality of recovery (QoR)-15 scores according to the use of maintenance anesthetics in the cervical spine surgery. Total intravenous anesthesia (TIVA) have been known to help reducing risks of postoperati...
News 16 results
https://www.medpagetoday.com/anesthesiology/anesthesiology/78719
Mar 21st, 2019 - Inhaled anesthesia may be safer for the heart than infusion agents, but that didn't lead to better survival in patients undergoing coronary artery bypass grafting (CABG) surgery in the MYRIAD trial. Those randomized to inhaled anesthesia had the s...
https://www.mdedge.com/fedprac/article/141649/hospital-medicine/symptoms-mimicking-those-hypokalemic-periodic-paralysis
COL (Ret) Terrence J. O’Neil, MD, FASN, USAFMC, Badar Siddiqui
Jul 17th, 2017 - Hypokalemic periodic paralysis (HPP) is a relatively common and potentially life-threating condition that can be either sporadic or recurring and has both inherited and acquired causes. 1 Familial HPP, on the other hand, is a rare condition (1:100.
http://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-daily-roundup-may-26-2020
For Immediate Release: May 26, 2020 The U.S. Food and Drug Administration today announced the following actions taken in its ongoing response effort to the COVID-19 pandemic: The FDA issued an Emergency Use Authorization (EUA) in response to conce...
http://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-december-22-2020
For Immediate Release: December 22, 2020 The U.S. Food and Drug Administration today announced the following actions taken in its ongoing response effort to the COVID-19 pandemic: The FDA has posted translations of the Moderna COVID-19 Vaccine fac...
http://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-daily-roundup-june-17-2020
For Immediate Release: June 17, 2020 The U.S. Food and Drug Administration today announced the following actions taken in its ongoing response effort to the COVID-19 pandemic: On June 16, 2020, the FDA approved an abbreviated new drug application ...