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About 1,333 results

ALLMedicine™ Malignant Hyperthermia Center

Research & Reviews  452 results

Dantrolene sodium fails to reverse robust brain hyperthermia induced by MDMA and metham...
https://doi.org/10.1007/s00213-023-06321-x
Psychopharmacology Cameron-Burr KT, Bola RA et. al.

Jan 27th, 2023 - Hyperthermia induced by psychomotor stimulants may cause leakage of the blood-brain barrier, vasogenic edema, and lethality in extreme cases. Current treatments such as whole-body cooling are only symptomatic and a clear need to develop pharmacolo...

Ryanodine receptor 1 related myasthenia like myopathy responsive to pyridostigmine.
https://doi.org/10.1016/j.ejmg.2023.104706
European Journal of Medical Genetics; Lester EB, Larsen MJ et. al.

Jan 21st, 2023 - Disease causing variants in the Ryanodine receptor 1 (RYR1) gene are a common cause for congenital myopathy and for malignant hyperthermia susceptibility. We report a 17 year old boy with congenital muscle weakness progressing to a myasthenia like...

Evolutionary isolation of ryanodine receptor isoform 1 for muscle-based thermogenesis i...
https://doi.org/10.1073/pnas.2117503120
Proceedings of the National Academy of Sciences of the Un... Singh DP, Pearce L et. al.

Jan 18th, 2023 - Resting skeletal muscle generates heat for endothermy in mammals but not amphibians, while both use the same Ca2+-handling proteins and membrane structures to conduct excitation-contraction coupling apart from having different ryanodine receptor (...

An Unusual Combination of Arthrogryposis, Gastroschisis, Cecal Volvulus, and Malignant ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9847307
The American Journal of Case Reports; Yeh J, Al Ashi A et. al.

Jan 14th, 2023 - BACKGROUND The purpose of this study is to discuss a patient with a history of conditions, including arthrogryposis, gastroschisis, and malignant hyperthermia, who presented with cecal volvulus requiring urgent surgical intervention. CASE REPORT A...

A Case Report of an Incidental Ultrasound Finding in a Suspected Malignant Hyperthermia...
https://doi.org/10.1213/XAA.0000000000001651
A&A Practice; Fu PH, Ho CN

Jan 5th, 2023 - Malignant hyperthermia (MH) is a rare but life-threatening genetic disorder of the skeletal muscles triggered by inhalation anesthetics or succinylcholine. A 49-year-old female developed symptoms of MH shortly after a lumbar surgery. Despite being...

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Guidelines  4 results

Consensus guidelines on perioperative management of malignant hyperthermia suspected or...
https://doi.org/10.1016/j.bja.2020.09.029
British Journal of Anaesthesia; Rüffert H, Bastian B et. al.

Nov 3rd, 2020 - Malignant hyperthermia is a potentially fatal condition, in which genetically predisposed individuals develop a hypermetabolic reaction to potent inhalation anaesthetics or succinylcholine. Because of the rarity of malignant hyperthermia and ethic...

Availability of dantrolene for the management of malignant hyperthermia crises: Europea...
https://doi.org/10.1016/j.bja.2020.04.089
British Journal of Anaesthesia; Glahn KPE, Bendixen D et. al.

Jun 28th, 2020 - Faced with a malignant hyperthermia crisis, the immediate access to sufficient dantrolene is essential to achieve the best possible outcome for the patient. However, malignant hyperthermia crises are rare, and there may be administrative pressures...

Malignant Hyperthermia-Susceptible Adult Patient and Ambulatory Surgery Center: Society...
https://doi.org/10.1213/ANE.0000000000004257
Anesthesia and Analgesia; Urman RD, Rajan N et. al.

Jun 6th, 2019 - This document represents a joint effort of the Society for Ambulatory Anesthesia (SAMBA) and the Ambulatory Surgical Care Committee of the American Society of Anesthesiologists (ASA) concerning the safe anesthetic care of adult malignant hyperther...

Special article: Creation of a guide for the transfer of care of the malignant hyperthe...
https://doi.org/10.1213/ANE.0b013e3182373b4a
Anesthesia and Analgesia; Larach MG, Dirksen SJ et. al.

Nov 5th, 2011 - Volatile anesthetics and/or succinylcholine may trigger a potentially lethal malignant hyperthermia (MH) event requiring critical care crisis management. If the MH triggering anesthetic is given in an ambulatory surgical center (ASC), then the pat...

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Drugs  19 results see all →

Clinicaltrials.gov  34 results

A Case Control Study of Patients With Diagnosis of Malignant Hyperthermia
https://clinicaltrials.gov/ct2/show/NCT02561598

Dec 15th, 2022 - The current study will use the combination of electronic medical records and genomic information in samples of persons who have exhibited signs of Malignant Hyperthermia (MH) or have family history or high risk of MH to see if risk factors can be ...

Comparison of Postoperative QoR-15 Scores Between Desflurane and Remimazolam in Lumbar Fusion Surgery
https://clinicaltrials.gov/ct2/show/NCT04983966

Sep 16th, 2022 - The purpose of the study is to compare the quality of recovery (QoR)-15 scores according to the use of maintenance anesthetics in the lumbar fusion surgery. Total intravenous anesthesia (TIVA) have been known to help reducing risks of postoperativ...

Screening of Malignant Hyperthermia Susceptible Individuals
https://clinicaltrials.gov/ct2/show/NCT05402839

Jun 2nd, 2022 - This study intends to target patients who underwent surgery under general anesthesia during the study period and developed malignant hyperthermia during or after surgery. Therefore, the total sample size was estimated to be about 50 people based o...

Malignant Hyperthermia in Czech Republic: Description of the Biggest Slavonic Group of Patients Investigated for Risk of Malignant Hyperthermia
https://clinicaltrials.gov/ct2/show/NCT05036148

Apr 15th, 2022 - We evaluated every referral to the MH centre since 2002 then. IVCT results, clinical data, personal and family history and molecular genetic data, have been recorded in an electronic medical record. Potential MHS patients, probands, were investiga...

Comparison of Postoperative QoR-15 Scores Between Sevoflurane and Remimazolam
https://clinicaltrials.gov/ct2/show/NCT05019222

Mar 31st, 2022 - The purpose of the study is to compare the quality of recovery (QoR)-15 scores according to the use of maintenance anesthetics in the cervical spine surgery. Total intravenous anesthesia (TIVA) have been known to help reducing risks of postoperati...

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News  16 results

Inhaled, IV Anesthetics Even in Cardiac Surgery Survival
https://www.medpagetoday.com/anesthesiology/anesthesiology/78719

Mar 21st, 2019 - Inhaled anesthesia may be safer for the heart than infusion agents, but that didn't lead to better survival in patients undergoing coronary artery bypass grafting (CABG) surgery in the MYRIAD trial. Those randomized to inhaled anesthesia had the s...

Symptoms Mimicking Those of Hypokalemic Periodic Paralysis Induced by Soluble Barium Poisoning
https://www.mdedge.com/fedprac/article/141649/hospital-medicine/symptoms-mimicking-those-hypokalemic-periodic-paralysis
COL (Ret) Terrence J. O’Neil, MD, FASN, USAFMC, Badar Siddiqui

Jul 17th, 2017 - Hypokalemic periodic paralysis (HPP) is a relatively common and potentially life-threating condition that can be either sporadic or recurring and has both inherited and acquired causes. 1 Familial HPP, on the other hand, is a rare condition (1:100.

Coronavirus (COVID-19) Update: Daily Roundup May 26, 2020
http://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-daily-roundup-may-26-2020

For Immediate Release: May 26, 2020 The U.S. Food and Drug Administration today announced the following actions taken in its ongoing response effort to the COVID-19 pandemic: The FDA issued an Emergency Use Authorization (EUA) in response to conce...

Coronavirus (COVID-19) Update: December 22, 2020
http://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-december-22-2020

For Immediate Release: December 22, 2020 The U.S. Food and Drug Administration today announced the following actions taken in its ongoing response effort to the COVID-19 pandemic: The FDA has posted translations of the Moderna COVID-19 Vaccine fac...

Coronavirus (COVID-19) Update: Daily Roundup June 17, 2020
http://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-daily-roundup-june-17-2020

For Immediate Release: June 17, 2020 The U.S. Food and Drug Administration today announced the following actions taken in its ongoing response effort to the COVID-19 pandemic: On June 16, 2020, the FDA approved an abbreviated new drug application ...

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Patient Education  8 results see all →