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About 13,205 results

ALLMedicine™ Organ Transplantation Center

Research & Reviews  4,647 results

Organ Transplantation Outcomes of Deceased Organ Donors in Organ Procurement Organizati...
https://doi.org/10.1177/15269248231164176
Progress in Transplantation (Aliso Viejo, Calif.); Vail EA, Schaubel DE et. al.

Mar 22nd, 2023 - Recovery of donated organs at organ procurement organization (OPO)-based recovery facilities has been proposed to improve organ donation outcomes, but few data exist to characterize differences between facilities and acute-care hospitals. To compa...

Liver Transplantation in Recipients With a Positive Crossmatch: A Retrospective Single-...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017503
Transplant International : Official Journal of the Europe... Krendl FJ, Fodor M et. al.

Mar 21st, 2023 - A positive crossmatch (XM+) is considered a contraindication to solid abdominal organ transplantation except liver transplantation (LT). Conflicting reports exist regarding the effects of XM+ on post-transplant outcomes. The goal of this retrospec...

Tonsillectomy Outcomes in Children After Solid-Organ Transplantation: A 15-Year Single-...
https://doi.org/10.1002/ohn.193
Otolaryngology--head and Neck Surgery : Official Journal ... Hazkani I, Hajnas N et. al.

Mar 21st, 2023 - Solid-organ transplantation (SOT) has become the standard of care for children with terminal organ failure. Long-term immunosuppression has improved survival substantially but is associated with secondary malignancies and impaired wound healing. O...

High frequency and mortality of head and neck malignancy in organ transplant recipients...
https://doi.org/10.1016/j.amjoto.2023.103827
American Journal of Otolaryngology; Conlon E, Fitzgerald C et. al.

Mar 19th, 2023 - Solid organ transplant recipients are recognized to carry a high burden of malignancy and frequently this cancer develops in the head and neck region. Furthermore, cancer of the head and neck post-transplant carries a significantly increased morta...

The unmet need of organ transplantation in Africa.
https://doi.org/10.1097/JS9.0000000000000025
International Journal of Surgery (London, England); Awuah WA, Ng JC et. al.

Mar 18th, 2023 - The unmet need of organ transplantation in Africa.|2023|Awuah WA,Ng JC,Bulut HI,Nazir A,Tenkorang PO,|

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Guidelines  18 results

Reproductive health after thoracic transplantation: An ISHLT expert consensus statement.
https://doi.org/10.1016/j.healun.2022.10.009
The Journal of Heart and Lung Transplantation : the Offic... Kittleson MM, DeFilippis EM et. al.

Dec 18th, 2022 - Pregnancy after thoracic organ transplantation is feasible for select individuals but requires multidisciplinary subspecialty care. Key components for a successful pregnancy after lung or heart transplantation include preconception and contracepti...

ISHLT position paper on thoracic organ transplantation in controlled donation after cir...
https://doi.org/10.1016/j.healun.2022.03.005
The Journal of Heart and Lung Transplantation : the Offic... Holm AM, Courtwright A et. al.

Apr 5th, 2022 - Controlled organ donation after circulatory determination of death is increasingly being used for the donation of organs also in thoracic transplantation. This document outlines the position of the International Society for Heart and Lung Transpla...

Cancer immunotherapy in special challenging populations: recommendations of the Advisor...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009216
Journal for Immunotherapy of Cancer; Gonzalez-Cao M, Puertolas T et. al.

Mar 31st, 2021 - Cancer immunotherapy based on the use of antibodies targeting the so-called checkpoint inhibitors, such as programmed cell death-1 receptor, its ligand, or CTLA-4, has shown durable clinical benefit and survival improvement in melanoma and other t...

Management of metabolic alterations in adult kidney transplant recipients: A joint posi...
https://doi.org/10.1016/j.numecd.2020.05.004
Nutrition, Metabolism, and Cardiovascular Diseases : NMCD; Conte C, Maggiore U et. al.

Jul 2nd, 2020 - Chronic metabolic alterations such as post-transplant diabetes mellitus (PTDM), dyslipidaemias and overweight/obesity significantly impact on kidney transplant (KT) outcomes. This joint position statement is based on the evidence on the management...

Guidelines for the Use of Transesophageal Echocardiography to Assist with Surgical Deci...
https://doi.org/10.1016/j.echo.2020.03.002
Journal of the American Society of Echocardiography : Off... Nicoara A, Skubas N et. al.

Jun 7th, 2020 - Intraoperative transesophageal echocardiography is a standard diagnostic and monitoring tool employed in the management of patients undergoing an entire spectrum of cardiac surgical procedures, ranging from "routine" surgical coronary revasculariz...

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Drugs  12 results see all →

Clinicaltrials.gov  319 results

FASHION Fabry Disease Hypertrophic Cardiomyopathy and Infammation
https://clinicaltrials.gov/ct2/show/NCT05761834

Mar 9th, 2023 - This study investigate whether partecipants with FD and HCM have a different inflammatory phenotype defined by plasma biomarkers, serum proteomic profile and transcriptomic analysis in peripheral blood mononuclear cells. Moreover, the investigator...

COVID19 Vaccine in SOT Adult Recipients
https://clinicaltrials.gov/ct2/show/NCT05116748

Mar 6th, 2023 - Several studies indicate that solid organ transplant recipients are at increased risk of severe SARS-CoV2 disease (COVID19) and increased mortality from it (Pereira MR, AmJT 2020; Fernandez-Ruiz M, AmJT 2020; Kates OS, ClinInfectDis 2020). Both IS...

Clinical and Laboratory Study of Methylmalonic Acidemia
https://clinicaltrials.gov/ct2/show/NCT00078078

Mar 3rd, 2023 - Methylmalonic acidemia (MMA), one of the most common inborn errors of organic acid metabolism, is heterogeneous in etiology and clinical manifestations. Affected patients with cblA, cblB and mut classes of MMA are medically fragile and can suffer ...

Genome Transplant Dynamics
https://clinicaltrials.gov/ct2/show/NCT02423070

Mar 3rd, 2023 - Acute rejection (AR) occurs within the first 6 months after transplantation in 20 percent of heart transplant patients and in 50 percent of lung-transplant patients. Given the often silent clinical presentation of AR, these patients require monito...

Efficacy, Safety, and Immunogenicity of Vaccine Reimmunization With a Third Homologous Versus Heterologous Dose Against COVID-19 in Patients Undergoing Solid Organ Transplantation.
https://clinicaltrials.gov/ct2/show/NCT05048940

Mar 2nd, 2023 - The main objective of this trial is to evaluate the immunogenicity of reimmunization against SARS-CoV-2 in patients undergoing solid organ transplantation with heterologous revaccination, testing whether in patients who received two doses of Spike...

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News  281 results

Biden Administration Announces Plan to Overhaul the Organ Transplant System
https://www.medpagetoday.com/transplantation/transplantation/103662

Mar 22nd, 2023 - The Biden administration said Wednesday it is launching an initiative to modernize the current organ procurement system to give it greater accountability and transparency. "Every day, patients and families across the United States rely on the Orga...

CTX130 Allogeneic CAR T-cell Therapy Shows Tolerability, Intriguing Activity in Advanced RCC
https://www.onclive.com/view/ctx130-allogeneic-car-t-cell-therapy-shows-tolerability-intriguing-activity-in-advanced-rcc

Nov 21st, 2022 - CTX130, an investigational allogeneic, CRISP/Cas9 gene-edited, anti-CD70 CAR T-cell therapy, was found to be safe with early signs of clinical activity in patients with advanced clear cell renal cell carcinoma (RCC), according to findings from the...

Onatasertib Plus Toripalimab Elicits Early Responses in Relapsed/Metastatic Cervical Cancer
https://www.onclive.com/view/onatasertib-plus-toripalimab-elicits-early-responses-in-relapsed-metastatic-cervical-cancer

Nov 17th, 2022 - Onatasertib (ATG-008) plus toripalimab elicited an objective response rate (ORR) of 52.4% in patients with relapsed or metastatic cervical cancer, irrespective of PD-L1 expression, according to preliminary data from the phase 2 TORCH trial (NCT035...

Nab-sirolimus Under Investigation in TSC1- and TSC2-mutated Gynecologic Cancers and Other Solid Tumors
https://www.onclive.com/view/nab-sirolimus-under-investigation-in-tsc1--and-tsc2-mutated-gynecologic-cancers

Nov 15th, 2022 - The mTOR inhibitor nab-sirolimus (ABI-009) may emerge as an effective and tolerable treatment in patients with gynecologic cancers with TSC1 and TSC2 mutations, according to Kathleen N. Moore, MD, MS. The phase 2 PRECISION 1 trial (NCT05103358) i...

Are Heart Transplantation Outcomes Worse After the New OPTN Policy?
https://www.medscape.com/viewarticle/981683

Oct 11th, 2022 - In 2016, the Organ Procurement and Transplantation Network (OPTN), which is administered by the United Network for Organ Sharing (UNOS), approved a new heart allocation policy that went into effect October 18, 2018. The revised policy reflected th...

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Patient Education  5 results see all →