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About 11,720 results

ALLMedicine™ Organ Transplantation Center

Research & Reviews  4,114 results

Complement (C1q) Binding to HLA Antibodies in a Solid-phase Immunoassay and Clinical Effect on Platelet Transfusion
https://clinicaltrials.gov/ct2/show/NCT02858323

Aug 4th, 2022 - Human leukocyte antigen (HLA) alloimmunization is common in patients undergoing frequent platelet transfusion, and is the most important cause of immune platelet refractoriness. Management strategies in HLA alloimmune platelet-refractory patients ...

HIV-to-HIV Transplant at MGH
https://clinicaltrials.gov/ct2/show/NCT02750397

Aug 3rd, 2022 - This is an observational study designed to evaluate safety and outcomes of solid organ transplantation in HIV+ recipients of HIV+ deceased donors. This study will evaluate overall survival and graft survival compared to transplantation with an HIV...

Fatal systemic disorder caused by biallelic variants in FARSA.
https://doi.org/10.1186/s13023-022-02457-9
Orphanet Journal of Rare Diseases; Kim SY, Ko S et. al.

Aug 3rd, 2022 - Aminoacyl tRNA transferases play an essential role in protein biosynthesis, and variants of these enzymes result in various human diseases. FARSA, which encodes the α subunit of cytosolic phenylalanyl-tRNA synthetase, was recently reported as a su...

Noninvasive Prediction of Immune Rejection After Liver Transplantation with T cell immu...
https://doi.org/10.1016/j.transproceed.2022.04.032
Transplantation Proceedings; Qin L, Zheng W et. al.

Aug 3rd, 2022 - T cell immunoglobulin domain, and mucin domain-3 (Tim-3) is associated with immunosuppression, immune tolerance, and rejection after organ transplantation, but there are no reports of rejection after human liver transplantation. This study aimed t...

Decision Making in the Context of Paediatric Solid Organ Transplantation Medicine.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329518
Transplant International : Official Journal of the Europe... Prüfe J

Aug 2nd, 2022 - This manuscript aims to outline ethical, legal, and psychosocial key situations in the context of transplantation under special consideration of children. Besides being particularly vulnerable, children as minors by law are not meant to consent to...

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Guidelines  14 results

ISHLT position paper on thoracic organ transplantation in controlled donation after cir...
https://doi.org/10.1016/j.healun.2022.03.005
The Journal of Heart and Lung Transplantation : the Offic... Holm AM, Courtwright A et. al.

Apr 5th, 2022 - Controlled organ donation after circulatory determination of death is increasingly being used for the donation of organs also in thoracic transplantation. This document outlines the position of the International Society for Heart and Lung Transpla...

Cancer immunotherapy in special challenging populations: recommendations of the Advisor...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009216
Journal for Immunotherapy of Cancer; Gonzalez-Cao M, Puertolas T et. al.

Mar 31st, 2021 - Cancer immunotherapy based on the use of antibodies targeting the so-called checkpoint inhibitors, such as programmed cell death-1 receptor, its ligand, or CTLA-4, has shown durable clinical benefit and survival improvement in melanoma and other t...

Management of metabolic alterations in adult kidney transplant recipients: A joint posi...
https://doi.org/10.1016/j.numecd.2020.05.004
Nutrition, Metabolism, and Cardiovascular Diseases : NMCD; Conte C, Maggiore U et. al.

Jul 2nd, 2020 - Chronic metabolic alterations such as post-transplant diabetes mellitus (PTDM), dyslipidaemias and overweight/obesity significantly impact on kidney transplant (KT) outcomes. This joint position statement is based on the evidence on the management...

Guidelines for the Use of Transesophageal Echocardiography to Assist with Surgical Deci...
https://doi.org/10.1016/j.echo.2020.03.002
Journal of the American Society of Echocardiography : Off... Nicoara A, Skubas N et. al.

Jun 7th, 2020 - Intraoperative transesophageal echocardiography is a standard diagnostic and monitoring tool employed in the management of patients undergoing an entire spectrum of cardiac surgical procedures, ranging from "routine" surgical coronary revasculariz...

Canadian Cardiovascular Society/Canadian Cardiac Transplant Network Position Statement ...
https://doi.org/10.1016/j.cjca.2019.12.025
The Canadian Journal of Cardiology; Chih S, McDonald M et. al.

Mar 9th, 2020 - Significant practice-changing developments have occurred in the care of heart transplantation candidates and recipients over the past decade. This Canadian Cardiovascular Society/Canadian Cardiac Transplant Network Position Statement provides evid...

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Drugs  9 results see all →

Clinicaltrials.gov  305 results

Complement (C1q) Binding to HLA Antibodies in a Solid-phase Immunoassay and Clinical Effect on Platelet Transfusion
https://clinicaltrials.gov/ct2/show/NCT02858323

Aug 4th, 2022 - Human leukocyte antigen (HLA) alloimmunization is common in patients undergoing frequent platelet transfusion, and is the most important cause of immune platelet refractoriness. Management strategies in HLA alloimmune platelet-refractory patients ...

HIV-to-HIV Transplant at MGH
https://clinicaltrials.gov/ct2/show/NCT02750397

Aug 3rd, 2022 - This is an observational study designed to evaluate safety and outcomes of solid organ transplantation in HIV+ recipients of HIV+ deceased donors. This study will evaluate overall survival and graft survival compared to transplantation with an HIV...

Fecal Microbiota Transplantation for C. Difficile Infection in Solid Organ Transplant Recipients
https://clinicaltrials.gov/ct2/show/NCT03617445

Aug 2nd, 2022 - Clostridium difficile (C.difficile) is a pathogen of major public health importance, especially in individuals with comorbid conditions such as solid organ transplantation (SOT). The incidence and adverse outcomes of CDI are greatly amplified in t...

Cell-Mediated Immunity Based Primary Prophylaxis for CMV Infection in Organ Transplant Recipients
https://clinicaltrials.gov/ct2/show/NCT02784756

Aug 2nd, 2022 - Cytomegalovirus (CMV) disease is an important cause of morbidity in solid organ transplantation recipients and remains the most common opportunistic viral infection in these patients. Standard CMV prevention strategies include universal prophylaxi...

Islet Transplantation in Type 1 Diabetic Patients Using the University of Illinois at Chicago (UIC) Protocol
https://clinicaltrials.gov/ct2/show/NCT00679042

Jul 27th, 2022 - This study is a Phase 3 single center, uncontrolled trial in which 1-3 allogeneic pancreatic islet transplants are performed for each study subject. Follow-up evaluations after transplant continue for 52 weeks after the final islet transplantation...

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News  243 results

When HIV Stigma and Conscientious Objection Collide
https://www.medscape.com/viewarticle/978615

Aug 4th, 2022 - A quiet academic debate over a physician's right to refuse specific healthcare services on the basis of moral or ethical objections or religious beliefs is spilling over into the HIV arena in some states, pitting some patients requesting preventiv...

Organ Decay Halted, Cell Function Restored in Pigs After Death: Study
https://www.medscape.com/viewarticle/978526

Aug 4th, 2022 - (Reuters) - Researchers have found that decay of tissues after death can be halted and cell functions restored based on early experiments in pigs that may eventually help increase the number of transplantable human organs. Sixty minutes after stop...

HBCU Medical Schools to Tackle Organ Transplant Disparities
https://www.medscape.com/viewarticle/973515

May 5th, 2022 - A new initiative aimed at increasing the number of Black Americans registered as organ donors and combating disparities among transplant recipients was announced Thursday by a coalition that includes the four medical schools at the nation's histor...

Concurrent Durvalumab/Chemoradiation Misses PFS End Point in Locally Advanced Cervical Cancer
https://www.onclive.com/view/concurrent-durvalumab-chemoradiation-misses-pfs-end-point-in-locally-advanced-cervical-cancer

Apr 20th, 2022 - Durvalumab (Imfinzi) given concurrently with chemoradiation was not found to significantly improve progression-free survival (PFS) vs chemoradiation alone in patients with locally advanced cervical cancer, missing the primary end point of the phas...

Donating Bodies to Science Carries Risks and Benefits
https://www.medscape.com/viewarticle/971030

Mar 28th, 2022 - It has become standard operating procedure that when you renew or obtain your driver's license, you're given the chance to sign on as an organ donor. Statistically, just over 50% of drivers sign on that dotted line, helping put a dent in the list ...

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Patient Education  3 results see all →