About 4,170 results

ALLMedicine™ Acute Liver Failure Center

Research & Reviews  1,502 results

Present and future management of viral hepatitis.
World Journal of Gastroenterology; González Grande R, Santaella Leiva I et. al.

Jan 25th, 2022 - Viral hepatitis can result in important morbidity and mortality, with its impact on health conditioned by the specific type of hepatitis, the geographical region of presentation and the development and access to new drugs, among other factors. Mos...

Ammonia Clearance with Different Continuous Renal Replacement Therapy Techniques in Pat...
Blood Purification; Fisher C, Baldwin I et. al.

Jan 19th, 2022 - Continuous renal replacement therapy (CRRT) can be used to treat hyperammonaemia. However, no study has assessed the effect of different CRRT techniques on ammonia clearance. We compared 3 different CRRT techniques in adult patients with hyperammo...

The Immune Landscape of Hepatitis B Virus-Related Acute Liver Failure by Integration An...
Journal of Immunology Research; Gong J, Chen Y et. al.

Jan 18th, 2022 - Hepatitis B virus-related acute liver failure (HBV-ALF) is a common type of liver failure, associated with high short-term mortality and morbidity rates. However, the immune landscape of HBV-ALF and its correlation with cell death are currently un...

Biliary atresia combined Wilson disease identified by whole exome sequencing in Vietnam...
Medicine Hoa NPA, Lien NTK et. al.

Jan 15th, 2022 - Hepatobiliary diseases such as biliary atresia (BA), Wilson disease, and progressive familial intrahepatic cholestasis are common causes of morbidity and mortality in young children. Affected patients progress rapidly to end-stage cirrhosis and re...

Serum superoxide dismutase level is a potential biomarker of disease prognosis in patie...
BMC Gastroenterology; He Y, Wang F et. al.

Jan 11th, 2022 - Viral hepatitis E clinically ranges from self-limiting hepatitis to lethal liver failure. Oxidative stress has been shown to mediate hepatic inflammation during HBV-induced liver failure. We investigated whether a biomarker of oxidative stress may...

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Guidelines  1 results

ESPEN practical guideline: Clinical nutrition in liver disease.
Clinical Nutrition (Edinburgh, Scotland); Bischoff SC, Bernal W et. al.

Nov 21st, 2020 - The Practical guideline is based on the current scientific ESPEN guideline on Clinical Nutrition in Liver Disease. It has been shortened and transformed into flow charts for easier use in clinical practice. The guideline is dedicated to all profes...

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Drugs  27 results see all →

Clinicaltrials.gov  30 results

A Multi-Center Trial to Study Acute Liver Failure in Adults

Dec 27th, 2021 - Although ALF is truly an orphan disease affecting only about 2,000 persons per year, its severity, its frequency among young adults, and its high resource utilization justifies the attention paid to it. In addition, ALF has captured the interest a...

TReatment for ImmUne Mediated PathopHysiology

Nov 22nd, 2021 - Pediatric Acute Liver Failure (PALF) is a rare, devastating condition that affects an estimated 250 children per year in North America, causing death in approximately 15% and the need for liver transplantation in an additional 20-30%. In the major...

Presepsin and Presepsin:Gelsolin Ratio in Sepsis-related Acute Kidney Injury

Oct 6th, 2021 - Presepsin is the 13-kDa soluble N-terminal fragment of the 55-kDa cluster of differentiation (CD) marker protein CD14, which is the receptor for lipopolysaccharide (LPS) and LPS-binding protein complexes. CD14 is a glycoprotein expressed mostly on...

36 Weeks Short-Term Optimization Treatment of Glucocorticosteroid in the Patients With Chronic Recurrent DILI

Sep 8th, 2021 - Drug-induced liver injury (DILI) refers to liver diseases caused by drugs and toxic substances. DILI is a clinical event that can be associated with severe outcomes such as acute liver failure. Up to now, approximately 1100 drugs, herbal products,...

Emergency Use of OCR-002 in Acute Liver Failure (ALF)

Jun 24th, 2021 - This is an open-label study in patients diagnosed with ALF who are not responding to the institution's standards of care. Standard of care may include, but is not limited to, administration of N-acetylcysteine, lactulose, hypothermia therapy, and ...

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News  104 results

Catequentinib Proves Efficacious, Well Tolerated in Synovial Sarcoma

Oct 6th, 2021 - Catequentinib (Anlotinib) significantly prolonged progression-free survival (PFS) in patients with synovial sarcoma who experienced disease progression following anthracycline-containing therapies, according to Brian A. Van Tine, MD, PhD, who adde...

COVID-19 and Liver Disease: Answering the Key Questions

Aug 18th, 2021 - For those of us treating patients with liver disease throughout the pandemic, we have anticipated evidence-based guidance regarding the contribution of specific liver disease phenotypes and immune suppression/transplantation on COVID-19 susceptibi...

Fast Five Quiz: Acetaminophen

Jul 22nd, 2021 - Acetaminophen is one of the most commonly used oral analgesic and antipyretic agents, with as many as 23% of US adults using an acetaminophen-containing medicine each week. It has an excellent safety profile when administered in proper therapeutic...

Avelumab Effective in PD-L1-Positive Metastatic Breast Cancer

Dec 20th, 2020 - Luc Y. Dirix, MD Treatment with the PD-L1 inhibitor avelumab demonstrated promising overall response rates (ORR) for patients with PD-L1—positive metastatic breast cancer, particularly for those with triple-negative disease, according to findings...

Liver Failure Management in the ICU: Clinical Practice Guidelines (2020)

Feb 28th, 2020 - In February 2020, a panel from the Society of Critical Care Medicine published clinical practice management guidelines on adult acute and acute-on-chronic liver failure, as encountered in the intensive care unit (ICU).[1] For patients with acute l...

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Patient Education  4 results see all →