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About 4,990 results

ALLMedicine™ Acute Liver Failure Center

Research & Reviews  1,747 results

Changes in Epidemiology of Acetaminophen Overdoses in an Urban County Hospital After 20...
https://doi.org/10.14309/ajg.0000000000001826
The American Journal of Gastroenterology; Long A, Magrath M et. al.

Aug 5th, 2022 - Acetaminophen (APAP) toxicity is the main cause of acute liver failure in the United States. A prior series (1992-1995) identified 71 hospitalized adults with APAP toxicity through the International Statistical Classification of Disease and Relate...

Heart rate variability is associated with encephalopathy and outcomes in pediatric acut...
https://doi.org/10.1038/s41390-022-02225-2
Pediatric Research; Pendergrast TR, Chapin CA et. al.

Aug 5th, 2022 - More than half of children with pediatric acute liver failure (PALF) experience hepatic encephalopathy (HE), which is related to poor outcomes; however, HE is difficult to diagnose in children. The objective of this study was to evaluate if heart ...

The successful application of hemoadsorption for extracorporeal liver support in a chil...
https://doi.org/10.1177/03913988221116135
The International Journal of Artificial Organs; Hui WF, Cheung WL et. al.

Aug 4th, 2022 - A 6-year-old boy developed acute liver failure with hepatic coma due to drug rash with eosinophilia and systemic symptoms (DRESS) after multiple antibiotics exposure. He had hyperbilirubinemia, elevated serum bile acids and hyperammonemia with pea...

A case of drug-induced acute liver failure caused by corticosteroids.
https://doi.org/10.1007/s12328-022-01661-1
Clinical Journal of Gastroenterology; Kajiwara A, Kawamura Y et. al.

Aug 2nd, 2022 - We report a 61-year-old man treated with betamethasone for sudden-onset deafness. Several days later, he had a temperature > 38 °C. He sought care at another hospital and was admitted based on abnormal liver function tests (aspartate aminotransfer...

Acute hepatitis-like presentation with cholestasis of CBFB-MYH11-positive acute myeloid...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9339180
Journal of Medical Case Reports; Spinelli I, De Santis A et. al.

Jul 31st, 2022 - Liver involvement in adults with acute myeloid leukemia is uncommon. Most of the case reports describe acute liver failure or obstructive jaundice, while acute hepatitis is rarely mentioned. We report a patient with acute myeloid leukemia who pres...

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Guidelines  1 results

ESPEN practical guideline: Clinical nutrition in liver disease.
https://doi.org/10.1016/j.clnu.2020.09.001
Clinical Nutrition (Edinburgh, Scotland); Bischoff SC, Bernal W et. al.

Nov 21st, 2020 - The Practical guideline is based on the current scientific ESPEN guideline on Clinical Nutrition in Liver Disease. It has been shortened and transformed into flow charts for easier use in clinical practice. The guideline is dedicated to all profes...

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Drugs  36 results see all →

Clinicaltrials.gov  82 results

Alterations of Gut Microbiota and Serum Biochemical Markers in DILI Patients
https://clinicaltrials.gov/ct2/show/NCT05465642

Jul 25th, 2022 - Background: Drug-induced liver injury(DILI) refers to the liver injury induced by all kinds of drugs and is the leading cause of acute liver failure worldwide. China has a large population base and a wide variety of clinical drugs, and it is commo...

TReatment for ImmUne Mediated PathopHysiology
https://clinicaltrials.gov/ct2/show/NCT04862221

Jul 5th, 2022 - Pediatric Acute Liver Failure (PALF) is a rare, devastating condition that affects an estimated 250 children per year in North America, causing death in approximately 15% and the need for liver transplantation in an additional 20-30%. In the major...

Prognosis of Patients With Acute-on-chronic Liver Failure
https://clinicaltrials.gov/ct2/show/NCT05393453

Jun 16th, 2022 - Patients with Acute on Chronic Liver Failure (ACLF) have high short-term mortality. The use of a severity score could define the patient's prognosis and would help determine in whom the treatment is effective. This study mainly prospectively analy...

Clinical Efficacy of Ulinastatin for Treatment of Sepsis With Systemic Inflammatory Response Syndrome
https://clinicaltrials.gov/ct2/show/NCT05391789

May 26th, 2022 - The study plans to recruit 120 septic patients with systemic inflammatory response syndrome. After signing the informed consent, they will be included as day 0. They will be randomly assigned to the ordinary dose group, high dose group and placebo...

The Effects of Double Plasma Molecular Adsorption System in Acute on Chronic Liver Failure Patients
https://clinicaltrials.gov/ct2/show/NCT05030571

Apr 8th, 2022 - Acute liver failure patients posed high mortality rate despite receiving standard therapy. The severity and mortality even higher in patients with underlying liver disease. Acute liver failure cause hyperinflammatory response in early stage and im...

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News  123 results

Cidofovir for Pediatric Adenovirus-Related Hepatitis Rapidly Reduces Viremia
https://www.medscape.com/viewarticle/976459

Jul 1st, 2022 - NEW YORK (Reuters Health) - Off-label use of cidofovir in children with acute liver failure and confirmed adenovirus infection cleared the virus or substantially reduced viremia in a small case series from Kings College Hospital, London. Dr. Avita...

CDC Updates Guidelines for Hepatitis Outbreak Among Children
https://www.medscape.com/viewarticle/973893

May 12th, 2022 - The CDC updated its recommendations for doctors and public health officials regarding the unusual outbreak of acute hepatitis among children. As of May 5, the CDC and state health departments are investigating 109 children with hepatitis of unknow...

Clinical Clues, Possible Culprit Identified in Kids' Mystery Hepatitis Cases
https://www.medpagetoday.com/infectiousdisease/hepatitis/98489

Apr 29th, 2022 - Adenovirus was detected in the blood specimens of all nine children with acute hepatitis infection identified in Alabama from October 2021 to February 2022, researchers found. The nine children were 0 to 6 years old and previously healthy, and mos...

Human CRP protects against acetaminophen-induced liver injury in mice
https://www.mdedge.com/internalmedicine/article/248909/hepatology/human-crp-protects-against-acetaminophen-induced-liver
Brandon May

Nov 18th, 2021 - While often linked to deleterious outcomes in certain disease states, the hepatocyte-produced inflammatory marker C-reactive protein (CRP) may be a checkpoint that protects against acetaminophen-induced acute liver injury, according to research fi.

COVID-19 and Liver Disease: Answering the Key Questions
https://www.medscape.com/viewarticle/956584

Aug 18th, 2021 - For those of us treating patients with liver disease throughout the pandemic, we have anticipated evidence-based guidance regarding the contribution of specific liver disease phenotypes and immune suppression/transplantation on COVID-19 susceptibi...

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Patient Education  7 results see all →