ALLMedicine™ Chronic Pancreatitis Center

Jan 22nd, 2022 - Pancreatitis is a complex syndrome that results from many etiologies. Large well-characterized cohorts are needed to further understand disease risk and prognosis. A pancreatitis cohort of over 4,200 patients and 24,000 controls were identified in...

Jan 19th, 2022 - Transforming growth factor-β (TGF-β)-mediated accumulation of extracellular matrix proteins such as collagen I is a common feature of fibrosis. Pancreatic stellate cells play an integral role in the pathogenesis of pancreatitis, and their profibro...

Jan 19th, 2022 - We developed an epidemiological algorithm to classify types of diabetes mellitus (DM) in chronic pancreatitis (CP), and applied it to a nationwide prospective longitudinal cohort of CP patients. Patients with definite CP (M-ANNHEIM criteria) were ...

Jan 19th, 2022 - This is a prospective observational study. Patients who need EUS-FNA/B for diagnosis of pancreatic solid lesions (pancreatic cancer, chronic pancreatitis, and autoimmune pancreatitis, etc)will be successively included in this study. The EUS-FNA/B ...

Jan 16th, 2022 - Genetic mutations in various pancreatic enzymes or their counteracting proteins have been linked to chronic pancreatitis. In particular, variants in the genes encoding pancreatic lipase (PNLIP) and carboxyl ester lipase (CEL) have been associated ...

Nov 2nd, 2020 - EUS remains a primary diagnostic tool for the evaluation of pancreaticobiliary disease. Although EUS combined with FNA or biopsy sampling is highly sensitive for the diagnosis of neoplasia within the pancreaticobiliary tract, limitations exist in ...

Aug 15th, 2020 - This paper is part of the international consensus guidelines on chronic pancreatitis, presenting for interventional endoscopy. An international working group with experts on interventional endoscopy evaluated 26 statements generated from evidence ...

Jul 8th, 2020 - Chronic pancreatitis (CP) is a complex inflammatory disease with variable presentations and outcomes. This statement is part of the international consensus guidelines on CP, specifically on the diagnostic role of endoscopic ultrasound (EUS). An in...

Jul 7th, 2020 - Patients with chronic pancreatitis (CP) have an increased risk of pancreatic cancer. We present the international consensus guidelines for surveillance of pancreatic cancer in CP. The international group evaluated 10 statements generated from evid...

May 18th, 2020 - Chronic pancreatitis is a complex multifactorial fibro-inflammatory disease. Consensus guidelines are needed for the histopathological evaluation of non-autoimmune chronic pancreatitis (CP). An international working group with experts on the histo...

Jan 19th, 2022 - This is a prospective observational study. Patients who need EUS-FNA/B for diagnosis of pancreatic solid lesions (pancreatic cancer, chronic pancreatitis, and autoimmune pancreatitis, etc)will be successively included in this study. The EUS-FNA/B ...

Jan 14th, 2022 - AIMS: To explore the correlation between the characteristics of microbial flora in pancreas and clinical and pathological characteristics of patients with various pancreatic diseases; To clarify the similarities and differences of microbial flora ...

Dec 15th, 2021 - Exocrine Pancreatic Insufficiency (EPI) is a condition where pancreatic enzyme quantity or activity is reduced below threshold needed for normal digestion. Symptoms include bloating, flatulence, diarrhea and steatorrhea. This is an observational s...

Dec 9th, 2021 - Niclosamide is an approved drug for the treatment of intestinal worm infections that can potentially induce the process of autophagy and thus significantly limit viral replication in cells. Camostat is approved in Japan for the treatment of chroni...

Dec 8th, 2021 - Acute pancreatitis (AP) is a common and devastating disease with an annual incidence of 22-30 per 100,000 in the UK. The incidence is increasing. AP is most commonly triggered by gallstones or alcohol excess and has a range of outcomes, from compl...

Oct 24th, 2021 - Key clinical point: Treatment with nonsteroidal anti-inflammatory drugs (NSAID) worsened exocrine pancreatic insufficiency (EPI) in patients with primary osteoarthritis in gastrointestinal comorbidity with EPI. Moreover, the trophologic status of.

Sep 28th, 2021 - More than half of chronic pancreatitis patients showed osteopathy on dual-energy x-ray absorptiometry (DXA) screening, researchers found in a prospective study. In a cross-sectional analysis involving nearly 300 patients with confirmed chronic pan...

Aug 31st, 2021 - Akash Goel, MD In recent months, there have been multiple publications around novel diagnostic testing which both might help to identify patients at risk for exocrine pancreatic insufficiency (EPI) and its clinical sequela. Our first study comes o.

Aug 28th, 2021 - Key clinical point: The prevalence of exocrine pancreatic insufficiency (EPI) was higher in patients with diffuse echogenicity of the pancreas on endoscopic ultrasound (EUS; fatty pancreas group) vs patients with chronic diarrhea without known pan.

May 20th, 2021 - For patients with necrotizing severe acute pancreatitis, several key clinical risk factors contributed to risk of developing infected pancreatic necrosis, a small study from Finland found. Independent risk factors included post-interventional panc...