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About 3,796 results

ALLMedicine™ Bacterial Pneumonia Center

Research & Reviews  1,595 results

Lefamulin: A Novel Oral and Intravenous Pleuromutilin for the Treatment of Community-Ac...
https://doi.org/10.1007/s40265-020-01443-4
Drugs Zhanel GG, Deng C et. al.

Nov 28th, 2020 - Lefamulin is a novel oral and intravenous (IV) pleuromutilin developed as a twice-daily treatment for community-acquired bacterial pneumonia (CABP). It is a semi-synthetic pleuromutilin with a chemical structure that contains a tricyclic core of f...

A phase Ib/IIa, randomised, double-blind, multicentre trial to assess the safety and ef...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686829
BMC Pulmonary Medicine; Laterre PF, Sánchez-García M et. al.

Nov 26th, 2020 - Community-acquired bacterial pneumonia (CABP) can lead to sepsis and is associated with high mortality rates in patients presenting with shock and/or respiratory failure and who require mechanical ventilation and admission to intensive care units,...

NLRP6 modulates neutrophil homeostasis in bacterial pneumonia-derived sepsis.
https://doi.org/10.1038/s41385-020-00357-4
Mucosal Immunology; Cai S, Paudel S et. al.

Nov 24th, 2020 - Bacterial pneumonia is a significant cause of morbidity, mortality, and health care expenditures. Optimum neutrophil recruitment and their function are critical defense mechanisms against respiratory pathogens. The nucleotide-binding oligomerizati...

Procalcitonin Correlates With but Is Not Superior to Other Diagnostic Markers of Bacter...
https://doi.org/10.1093/ajcp/aqaa148
American Journal of Clinical Pathology; Ayala-Lopez N, Peaper DR et. al.

Nov 19th, 2020 - Despite extensive research on procalcitonin (PCT)-guided therapy in lower respiratory tract infections, the association between PCT and bacterial pneumonia remains unclear. We evaluated retrospectively the performance of PCT in patients presenting...

Estrogen Alleviates Sex-Dependent Differences in Lung Bacterial Clearance and Mortality...
https://doi.org/10.1089/neu.2020.7327
Journal of Neurotrauma; Pittet JF, Hu P et. al.

Nov 18th, 2020 - Traumatic brain injury (TBI) is the leading cause of injury-related death and disability in patients under the age of 46 years. Survivors of the initial injury often endure systemic complications such as pulmonary infection and Pseudomonas aerugin...

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Guidelines  7 results

Shared Decision-Making for Administering PCV13 in Older Adults
https://www.aafp.org/afp/2020/0201/p134.html
American Family Physician; Shah AA,et al

Jan 31st, 2020 - Streptococcus pneumoniae infection, the most common cause of bacterial pneumonia, leads to significant morbidity and mortality in older people. With the addition of the pneumococcal conjugate vaccine to childhood immunization schedules in 2000, he...

Melinta Therapeutics Announces U.S. FDA Approval of Supplemental New Drug Application for BAXDELA® (delafloxacin) for the Treatment of Community-Acquired Bacterial Pneumonia (CABP)
http://ir.melinta.com/news-releases/news-release-details/melinta-therapeutics-announces-us-fda-approval-supplemental-new

Oct 23rd, 2019 - Melinta Therapeutics, Inc. (NASDAQ: MLNT), a commercial-stage company focused on the development and commercialization of novel antibiotics to treat serious bacterial infections, today announced the U.S. Food and Drug Administration (FDA) has appr...

Improving Conduct and Feasibility of Clinical Trials to Evaluate Antibacterial Drugs to...
https://doi.org/10.1093/cid/ciw258
Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America; Knirsch C, Alemayehu D et. al.

Aug 2nd, 2016 - The etiology of hospital-acquired or ventilator-associated bacterial pneumonia (HABP/VABP) is often multidrug-resistant infections. The evaluation of new antibacterial drugs for efficacy in this population is important, as many antibacterial drugs...

Streamlining Safety Data Collection in Hospital-Acquired Bacterial Pneumonia and Ventil...
https://doi.org/10.1093/cid/ciw316
Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America; Donnelly H, Alemayehu D et. al.

Aug 2nd, 2016 - Resistant bacteria are one of the leading causes of hospital-acquired/ventilator-associated bacterial pneumonia (HABP/VABP). HABP/VABP trials are complex and difficult to conduct due to the large number of medical procedures, adverse events, and c...

XENLETA™ (lefamulin) Website for Healthcare Professionals
https://www.xenleta.com/

community-acquired bacterial pneumonia See XENLETA™ (lefamulin) clinical trial results and product attributes

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Drugs  137 results see all →

Clinicaltrials.gov  1,861 results

Lefamulin: A Novel Oral and Intravenous Pleuromutilin for the Treatment of Community-Ac...
https://doi.org/10.1007/s40265-020-01443-4
Drugs Zhanel GG, Deng C et. al.

Nov 28th, 2020 - Lefamulin is a novel oral and intravenous (IV) pleuromutilin developed as a twice-daily treatment for community-acquired bacterial pneumonia (CABP). It is a semi-synthetic pleuromutilin with a chemical structure that contains a tricyclic core of f...

A phase Ib/IIa, randomised, double-blind, multicentre trial to assess the safety and ef...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686829
BMC Pulmonary Medicine; Laterre PF, Sánchez-García M et. al.

Nov 26th, 2020 - Community-acquired bacterial pneumonia (CABP) can lead to sepsis and is associated with high mortality rates in patients presenting with shock and/or respiratory failure and who require mechanical ventilation and admission to intensive care units,...

NLRP6 modulates neutrophil homeostasis in bacterial pneumonia-derived sepsis.
https://doi.org/10.1038/s41385-020-00357-4
Mucosal Immunology; Cai S, Paudel S et. al.

Nov 24th, 2020 - Bacterial pneumonia is a significant cause of morbidity, mortality, and health care expenditures. Optimum neutrophil recruitment and their function are critical defense mechanisms against respiratory pathogens. The nucleotide-binding oligomerizati...

Procalcitonin Correlates With but Is Not Superior to Other Diagnostic Markers of Bacter...
https://doi.org/10.1093/ajcp/aqaa148
American Journal of Clinical Pathology; Ayala-Lopez N, Peaper DR et. al.

Nov 19th, 2020 - Despite extensive research on procalcitonin (PCT)-guided therapy in lower respiratory tract infections, the association between PCT and bacterial pneumonia remains unclear. We evaluated retrospectively the performance of PCT in patients presenting...

Estrogen Alleviates Sex-Dependent Differences in Lung Bacterial Clearance and Mortality...
https://doi.org/10.1089/neu.2020.7327
Journal of Neurotrauma; Pittet JF, Hu P et. al.

Nov 18th, 2020 - Traumatic brain injury (TBI) is the leading cause of injury-related death and disability in patients under the age of 46 years. Survivors of the initial injury often endure systemic complications such as pulmonary infection and Pseudomonas aerugin...

see more →

News  193 results

How the COVID Pandemic May End: Lessons From the 1918 Flu
https://www.medscape.com/viewarticle/940788

Nov 11th, 2020 - Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. The Spanish flu hit in the fall of 1918; a second surge occurred from January to April 1919, and a smaller one followed in the winter of 1920. Forty million peop...

As COVID-19 Cases Spike, Pneumonia Vaccine Demand Rockets and Europe Runs Low
https://www.staging.medscape.com/viewarticle/939667

Oct 25th, 2020 - MILAN/FRANKFURT/NEW YORK (Reuters) - As COVID-19 infections rise, people seeking to avoid one lung disease compounding another are queuing up to get inoculated against bacterial pneumonia, causing shortages of a Merck & Co vaccine in parts of Euro...

Fast Five Quiz: Pneumonia Key Aspects
https://reference.medscape.com/viewarticle/922410_2

Mar 22nd, 2020 - Physical examination findings may vary depending on the type of organism, severity of infection, coexisting host factors, and presence of complications. Signs of bacterial pneumonia may include the following: Hyperthermia (fever, typically > 38°C)...

Fast Five Quiz: Pneumonia Key Aspects
https://reference.medscape.com/viewarticle/922410

Mar 22nd, 2020 - Bacterial pneumonia is caused by a pathogenic infection of the lungs and may present as a primary disease process or as the final, fatal disorder, primarily in an individual who is already debilitated. Community-acquired pneumonia (CAP) is one of ...

Shared Decision-Making for Administering PCV13 in Older Adults
https://www.aafp.org/afp/2020/0201/p134.html
American Family Physician; Shah AA,et al

Jan 31st, 2020 - Streptococcus pneumoniae infection, the most common cause of bacterial pneumonia, leads to significant morbidity and mortality in older people. With the addition of the pneumococcal conjugate vaccine to childhood immunization schedules in 2000, he...

see more →

Patient Education  3 results see all →