ALLMedicine™ Bacterial Sepsis Center

Jul 16th, 2021 - The COVID-19 pandemic is a global public health crisis with considerable mortality and morbidity. A role for cytokine storm and therapeutic immunomodulation in a subgroup of patients with severe COVID-19 was proposed early in the pandemic. The con...

Jun 30th, 2021 - Antimicrobial peptides (AMPs) contribute to an effective protection against infections. The antibacterial function of AMPs depends on their interactions with microbial membranes and lipids, such as lipopolysaccharide (LPS; endotoxin). Hyperinflamm...

Jun 12th, 2021 - The mechanisms driving acute kidney injury (AKI) in critically ill COVID-19 patients are unclear. We collected kidney biopsies from COVID-19 AKI patients within 30 min after death in order to examine the histopathology and perform mRNA expression ...

May 19th, 2021 - Although clinical presentation of coronavirus disease 2019 has been extensively described, immune response to severe acute respiratory syndrome coronavirus 2 remains yet not fully understood. Similarities with bacterial sepsis were observed; howev...

May 6th, 2021 - Early diagnosis and antibiotic administration are essential for reducing sepsis morbidity and mortality; however, diagnosis remains difficult due to complex pathogenesis and presentation. We created a machine learning model for bacterial sepsis id...

Oct 30th, 2018 - The pathophysiology of macrophage activation syndrome has been mainly studied in pediatric genetic primary forms. There is little data in secondary forms related to bacterial sepsis. Because of the seriousness of this entity (43% of deaths in inte...

Sep 5th, 2018 - Vaccines work by stimulating the body to produce a high-quality, rapid and specific immune response upon exposure to infection by a particular disease-causing microorganism - the microorganism targeted by the vaccine. Evidence is emerging that som...

Aug 1st, 2018 - The delayed administration of an adequate antimicrobial therapy is a strong predictor of impaired outcome in patients with bacterial sepsis. Therefore, the current Surviving Sepsis Campaign guidelines (2016) recommend that administration of intrav...

Jun 29th, 2018 - Detailed objectives of the study are: To compare the efficacy of an optimised vancomycin dosing regimen to a standard vancomycin dosing regimen in patients with late onset, bacterial sepsis, known or suspected to be caused by Gram-positive microor...

Apr 19th, 2018 - The investigators will undertake a proof-of-concept, pilot, prospective, observational trial that aims to recruit ~90 children from the Seattle Children's Hospital Pediatric Intensive Care Unit (PICU) and Cardiac Intensive Care Unit (CICU). The st...

Oct 16th, 2020 - Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection that can be bacterial, fungal, protozoal, or viral in origin, ...

Oct 16th, 2020 - Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection that can be bacterial, fungal, protozoal, or viral in origin, ...

Sep 8th, 2020 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. The immune system overactivation known as a "cytokine storm" does not play a major role in more severe COVID-19 outcomes, according to unexpected ...

Summary Company Announcement Date: June 25, 2017 FDA Publish Date: February 07, 2018 Product Type: Drugs Reason for Announcement: Recall Reason Description Due to Lack of Sterility Assurance Company Name: PharMEDium Services Brand Name: Brand Name...

Summary Company Announcement Date: June 16, 2017 FDA Publish Date: February 08, 2018 Product Type: Drugs Reason for Announcement: Recall Reason Description Due to Lack of Sterility Assurance Company Name: Alvogen Brand Name: Brand Name(s) Alvogen ...