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About 1,263 results

ALLMedicine™ Bacterial Sepsis Center

Research & Reviews  613 results

Novel TLR2xTLR4 Bispecific Antibody Inhibits Bacterial Sepsis.
https://doi.org/10.1089/mab.2020.0025
Monoclonal Antibodies in Immunodiagnosis and Immunotherapy; Sato M, Takeuchi S et. al.

Dec 21st, 2020 - Toll-like receptors (TLRs) sense microbial infection through recognition of pathogen-associated molecular patterns. For example, TLR4 responds to the lipopolysaccharide of gram-negative bacteria, whereas TLR2 recognizes a broad range of microbial ...

Antibiotic therapeutic drug monitoring in intensive care patients treated with differen...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689974
Critical Care (London, England); Kühn D, Metz C et. al.

Nov 26th, 2020 - Effective antimicrobial treatment is key to reduce mortality associated with bacterial sepsis in patients on intensive care units (ICUs). Dose adjustments are often necessary to account for pathophysiological changes or renal replacement therapy. ...

Validation of Inflammopathic, Adaptive, and Coagulopathic Sepsis Endotypes in Coronavir...
https://doi.org/10.1097/CCM.0000000000004786
Critical Care Medicine; Sweeney TE, Liesenfeld O et. al.

Nov 17th, 2020 - Complex critical syndromes like sepsis and coronavirus disease 2019 may be composed of underling "endotypes," which may respond differently to treatment. The aim of this study was to test whether a previously defined bacterial sepsis endotypes cla...

miRNA-23b as a biomarker of culture-positive neonatal sepsis.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542968
Molecular Medicine (Cambridge, Mass.); Fatmi A, Rebiahi SA et. al.

Oct 9th, 2020 - Neonatal sepsis remains an important cause of morbidity and mortality. The ability to quickly and accurately diagnose neonatal sepsis based on clinical assessments and laboratory blood tests remains difficult, where haemoculture is the gold standa...

Lipoprotein concentrations over time in the intensive care unit COVID-19 patients: Resu...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7514065
PloS One; Tanaka S, De Tymowski C et. al.

Sep 24th, 2020 - Severe acute respiratory syndrome coronavirus2 has caused a global pandemic of coronavirus disease 2019 (COVID-19). High-density lipoproteins (HDLs), particles chiefly known for their reverse cholesterol transport function, also display pleiotropi...

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Guidelines  4 results

Management of Neonates Born at ?34 6/7 Weeks’ Gestation With Suspected or Proven Early-Onset...
http://pediatrics.aappublications.org/content/142/6/e20182896
Puopolo, Karen M.

Nov 30th, 2018 - Early-onset sepsis (EOS) remains a serious and often fatal illness among infants born preterm, particularly among newborn infants of the lowest gestational age. Currently, most preterm infants with very low birth weight are treated empirically wit.

Beating the Clock to Reduce Sepsis Mortality
https://news.aamc.org/patient-care/article/beating-clock-reduce-sepsis-mortality/
Robin Warshaw

Dec 11th, 2017 - Often overlooked and more difficult to identify than many other life-threatening conditions, sepsis causes one-third to one-half of all deaths in U. S.

Does Early Goal-Directed Therapy Decrease Mortality Compared with Standard Care in Patients ...
http://www.aaem.org/UserFiles/DoesEarlyGoal-DirectedTherapyDecreaseMortalityComparedwithStandardCareinPatientswithSepticShock_.pdf
Robert Sherwin, Michael Winters

Feb 16th, 2016 - Improvements in usual care can largely be attributed to the emphasis that the EGDT study placed on caring for patients with sepsis. Patients in the usual care arms of the ProCESS, ARISE, and ProMISE trials received aggressive intravenous fluids an.

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Clinicaltrials.gov  627 results

Novel TLR2xTLR4 Bispecific Antibody Inhibits Bacterial Sepsis.
https://doi.org/10.1089/mab.2020.0025
Monoclonal Antibodies in Immunodiagnosis and Immunotherapy; Sato M, Takeuchi S et. al.

Dec 21st, 2020 - Toll-like receptors (TLRs) sense microbial infection through recognition of pathogen-associated molecular patterns. For example, TLR4 responds to the lipopolysaccharide of gram-negative bacteria, whereas TLR2 recognizes a broad range of microbial ...

Antibiotic therapeutic drug monitoring in intensive care patients treated with differen...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689974
Critical Care (London, England); Kühn D, Metz C et. al.

Nov 26th, 2020 - Effective antimicrobial treatment is key to reduce mortality associated with bacterial sepsis in patients on intensive care units (ICUs). Dose adjustments are often necessary to account for pathophysiological changes or renal replacement therapy. ...

Validation of Inflammopathic, Adaptive, and Coagulopathic Sepsis Endotypes in Coronavir...
https://doi.org/10.1097/CCM.0000000000004786
Critical Care Medicine; Sweeney TE, Liesenfeld O et. al.

Nov 17th, 2020 - Complex critical syndromes like sepsis and coronavirus disease 2019 may be composed of underling "endotypes," which may respond differently to treatment. The aim of this study was to test whether a previously defined bacterial sepsis endotypes cla...

miRNA-23b as a biomarker of culture-positive neonatal sepsis.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542968
Molecular Medicine (Cambridge, Mass.); Fatmi A, Rebiahi SA et. al.

Oct 9th, 2020 - Neonatal sepsis remains an important cause of morbidity and mortality. The ability to quickly and accurately diagnose neonatal sepsis based on clinical assessments and laboratory blood tests remains difficult, where haemoculture is the gold standa...

Lipoprotein concentrations over time in the intensive care unit COVID-19 patients: Resu...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7514065
PloS One; Tanaka S, De Tymowski C et. al.

Sep 24th, 2020 - Severe acute respiratory syndrome coronavirus2 has caused a global pandemic of coronavirus disease 2019 (COVID-19). High-density lipoproteins (HDLs), particles chiefly known for their reverse cholesterol transport function, also display pleiotropi...

see more →

News  19 results

Platelet Contamination Leads to 3 Deaths
https://www.mdedge.com/fedprac/article/171390/mixed-topics/platelet-contamination-leads-3-deaths
Jan Dyer

Aug 15th, 2018 - Platelet-transmitted bacterial infections persist as a cause of transfusion-associated morbidity and mortality, according to researchers writing in Mortality and Morbidity Weekly Report. They describe 2 separate clusters of platelet transfusion-a.

Whole blood PCR improves diagnosis of pediatric bacterial sepsis
https://www.mdedge.com/familymedicine/article/140453/infectious-diseases/whole-blood-pcr-improves-diagnosis-pediatric
Pediatric News; Bruce Jancin

Jun 14th, 2017 - MADRID – Whole blood multiplex polymerase chain reaction (PCR) holds considerable promise as a rapid noninvasive test to improve diagnosis of life-threatening bacterial infections in children with suspected sepsis yet negative blood cultures, Clar.

Low UTI rates after foregoing prophylactic antibiotics for cystoscopy
https://www.mdedge.com/hematology-oncology/article/81272/genitourinary-cancer/low-uti-rates-after-foregoing-prophylactic
Amy Karon

Mar 27th, 2014 - Only 1. 9% of tumor patients who did not have prophylactic antibiotics developed febrile urinary tract infections after flexible cystoscopy, according to research published in the April issue of European Urology.

Assay Could Speed Diagnosis of Bacterial Sepsis
https://www.mdedge.com/authors/jeff-evans?page=28
Jeff Evans

Jan 1st, 2010 - A testing method that uses positive blood cultures and an automated DNA-based polymerase chain reaction and microarray system accurately identified bacteria in sepsis much faster than a standard culture-based process. The test identified bacterial.

FDA Issues Boxed Warning for Efalizumab
https://www.medpagetoday.com/infectiousdisease/publichealth/11358

Oct 16th, 2008 - ROCKVILLE, Md., Oct. 16 -- The FDA today announced that efalizumab (Raptiva) must carry a boxed warning to highlight the risk of life-threatening infections, including progressive multifocal leukoencephalopathy (PML). The warning will also include...

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