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About 798 results

ALLMedicine™ Bacterial Sepsis Center

Research & Reviews  282 results

Is severe COVID-19 a cytokine storm syndrome: a hyperinflammatory debate.
https://doi.org/10.1097/BOR.0000000000000822
Current Opinion in Rheumatology; Mehta P, Fajgenbaum DC

Jul 16th, 2021 - The COVID-19 pandemic is a global public health crisis with considerable mortality and morbidity. A role for cytokine storm and therapeutic immunomodulation in a subgroup of patients with severe COVID-19 was proposed early in the pandemic. The con...

Cathelicidin and PMB neutralize endotoxins by multifactorial mechanisms including LPS i...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8271772
Proceedings of the National Academy of Sciences of the Un... Schromm AB, Paulowski L et. al.

Jun 30th, 2021 - Antimicrobial peptides (AMPs) contribute to an effective protection against infections. The antibacterial function of AMPs depends on their interactions with microbial membranes and lipids, such as lipopolysaccharide (LPS; endotoxin). Hyperinflamm...

Comparison of renal histopathology and gene expression profiles between severe COVID-19...
https://doi.org/10.1186/s13054-021-03631-4
Critical Care (London, England); Volbeda M, Jou-Valencia D et. al.

Jun 12th, 2021 - The mechanisms driving acute kidney injury (AKI) in critically ill COVID-19 patients are unclear. We collected kidney biopsies from COVID-19 AKI patients within 30 min after death in order to examine the histopathology and perform mRNA expression ...

Comparison of Circulating Immune Cells Profiles and Kinetics Between Coronavirus Diseas...
https://doi.org/10.1097/CCM.0000000000005088
Critical Care Medicine; de Roquetaillade C, Mansouri S et. al.

May 19th, 2021 - Although clinical presentation of coronavirus disease 2019 has been extensively described, immune response to severe acute respiratory syndrome coronavirus 2 remains yet not fully understood. Similarities with bacterial sepsis were observed; howev...

Aiding clinical assessment of neonatal sepsis using hematological analyzer data with ma...
https://doi.org/10.1111/ijlh.13549
International Journal of Laboratory Hematology; Huang B, Wang R et. al.

May 6th, 2021 - Early diagnosis and antibiotic administration are essential for reducing sepsis morbidity and mortality; however, diagnosis remains difficult due to complex pathogenesis and presentation. We created a machine learning model for bacterial sepsis id...

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Drugs  2 results see all →

Clinicaltrials.gov  8 results

Characterization of the Inflammatory Profile of Patients With Macrophage Activation Syndrome Secondary to Bacterial Sepsis
https://clinicaltrials.gov/ct2/show/NCT03721809

Oct 30th, 2018 - The pathophysiology of macrophage activation syndrome has been mainly studied in pediatric genetic primary forms. There is little data in secondary forms related to bacterial sepsis. Because of the seriousness of this entity (43% of deaths in inte...

Non-specific Effects of Rabies Vaccine
https://clinicaltrials.gov/ct2/show/NCT03656198

Sep 5th, 2018 - Vaccines work by stimulating the body to produce a high-quality, rapid and specific immune response upon exposure to infection by a particular disease-causing microorganism - the microorganism targeted by the vaccine. Evidence is emerging that som...

Impact of qSOFA Calculation on the Timing of Antimicrobial Therapy in the Emergency Department
https://clinicaltrials.gov/ct2/show/NCT03299894

Aug 1st, 2018 - The delayed administration of an adequate antimicrobial therapy is a strong predictor of impaired outcome in patients with bacterial sepsis. Therefore, the current Surviving Sepsis Campaign guidelines (2016) recommend that administration of intrav...

Neonatal Vancomycin Trial
https://clinicaltrials.gov/ct2/show/NCT02790996

Jun 29th, 2018 - Detailed objectives of the study are: To compare the efficacy of an optimised vancomycin dosing regimen to a standard vancomycin dosing regimen in patients with late onset, bacterial sepsis, known or suspected to be caused by Gram-positive microor...

Genotypes and Phenotypes in Pediatric SIRS and Sepsis
https://clinicaltrials.gov/ct2/show/NCT02728401

Apr 19th, 2018 - The investigators will undertake a proof-of-concept, pilot, prospective, observational trial that aims to recruit ~90 children from the Seattle Children's Hospital Pediatric Intensive Care Unit (PICU) and Cardiac Intensive Care Unit (CICU). The st...

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News  27 results

Does COVID-19 Cause Sepsis?
https://www.medscape.com/viewarticle/939038

Oct 16th, 2020 - Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection that can be bacterial, fungal, protozoal, or viral in origin, ...

Does COVID-19 Cause Sepsis?
https://www.staging.medscape.com/viewarticle/939038

Oct 16th, 2020 - Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection that can be bacterial, fungal, protozoal, or viral in origin, ...

Unexpected Results in New COVID-19 'Cytokine Storm' Data
https://www.medscape.com/viewarticle/937044

Sep 8th, 2020 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. The immune system overactivation known as a "cytokine storm" does not play a major role in more severe COVID-19 outcomes, according to unexpected ...

PharMEDium Services Issues Voluntary Nationwide Recall of Specific Lots of Potassium Phosphate and Succinylcholine Chloride Due to a Lack of Sterility Assurance | FDA
https://www.fda.gov/safety/recalls-market-withdrawals-safety-alerts/pharmedium-services-issues-voluntary-nationwide-recall-specific-lots-potassium-phosphate-and

Summary Company Announcement Date: June 25, 2017 FDA Publish Date: February 07, 2018 Product Type: Drugs Reason for Announcement: Recall Reason Description Due to Lack of Sterility Assurance Company Name: PharMEDium Services Brand Name: Brand Name...

Alvogen Issues Voluntary Nationwide Recall of Clindamycin Injection Due to a Potential for a Lack of Sterility Assurance | FDA
https://www.fda.gov/safety/recalls-market-withdrawals-safety-alerts/alvogen-issues-voluntary-nationwide-recall-clindamycin-injection-due-potential-lack-sterility

Summary Company Announcement Date: June 16, 2017 FDA Publish Date: February 08, 2018 Product Type: Drugs Reason for Announcement: Recall Reason Description Due to Lack of Sterility Assurance Company Name: Alvogen Brand Name: Brand Name(s) Alvogen ...

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