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About 1,256 results

ALLMedicine Bacterial Sepsis Center

Research & Reviews  591 results

High sPLA2-IIA level is associated with eicosanoid metabolism in patients with bacteria...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065791
PloS One; Ahmad NS, Tan TL et. al.

Mar 11th, 2020 - The aim of this study was to determine the association between secretory phospholipase A2 group IIA (sPLA2-IIA) and eicosanoid pathway metabolites in patients with bacterial sepsis syndrome (BSS). Levels of sPLA2-IIA, eicosanoids prostaglandin (PG...

An immune-cell signature of bacterial sepsis.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235950
Nature Medicine; Reyes M, Filbin MR et. al.

Feb 18th, 2020 - Dysregulation of the immune response to bacterial infection can lead to sepsis, a condition with high mortality. Multiple whole-blood gene-expression studies have defined sepsis-associated molecular signatures, but have not resolved changes in tra...

The role of type 1 interferons in coagulation induced by gram-negative bacteria.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118812
Blood Yang X, Cheng X et. al.

Feb 5th, 2020 - Bacterial infection not only stimulates innate immune responses but also activates coagulation cascades. Overactivation of the coagulation system in bacterial sepsis leads to disseminated intravascular coagulation (DIC), a life-threatening conditi...

Management of HIV-infected patients in the intensive care unit.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7095039
Intensive Care Medicine; Barbier F, Mer M et. al.

Feb 5th, 2020 - The widespread use of combination antiretroviral therapies (cART) has converted the prognosis of HIV infection from a rapidly progressive and ultimately fatal disease to a chronic condition with limited impact on life expectancy. Yet, HIV-infected...

PCR for the detection of pathogens in neonatal early onset sepsis.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6980546
PloS One; Oeser C, Pond M et. al.

Jan 24th, 2020 - A large proportion of neonates are treated for presumed bacterial sepsis with broad spectrum antibiotics even though their blood cultures subsequently show no growth. This study aimed to investigate PCR-based methods to identify pathogens not dete...

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Guidelines  3 results

Management of Neonates Born at ?34 6/7 Weeks’ Gestation With Suspected or Proven Early-Onset...
http://pediatrics.aappublications.org/content/142/6/e20182896
Puopolo, Karen M.

Nov 30th, 2018 - Early-onset sepsis (EOS) remains a serious and often fatal illness among infants born preterm, particularly among newborn infants of the lowest gestational age. Currently, most preterm infants with very low birth weight are treated empirically wit.

Beating the Clock to Reduce Sepsis Mortality
https://news.aamc.org/patient-care/article/beating-clock-reduce-sepsis-mortality/
Robin Warshaw

Dec 11th, 2017 - Often overlooked and more difficult to identify than many other life-threatening conditions, sepsis causes one-third to one-half of all deaths in U. S.

Does Early Goal-Directed Therapy Decrease Mortality Compared with Standard Care in Patients ...
http://www.aaem.org/UserFiles/DoesEarlyGoal-DirectedTherapyDecreaseMortalityComparedwithStandardCareinPatientswithSepticShock_.pdf
Robert Sherwin, Michael Winters

Feb 16th, 2016 - Improvements in usual care can largely be attributed to the emphasis that the EGDT study placed on caring for patients with sepsis. Patients in the usual care arms of the ProCESS, ARISE, and ProMISE trials received aggressive intravenous fluids an.

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Clinicaltrials.gov  625 results

High sPLA2-IIA level is associated with eicosanoid metabolism in patients with bacteria...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065791
PloS One; Ahmad NS, Tan TL et. al.

Mar 11th, 2020 - The aim of this study was to determine the association between secretory phospholipase A2 group IIA (sPLA2-IIA) and eicosanoid pathway metabolites in patients with bacterial sepsis syndrome (BSS). Levels of sPLA2-IIA, eicosanoids prostaglandin (PG...

An immune-cell signature of bacterial sepsis.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235950
Nature Medicine; Reyes M, Filbin MR et. al.

Feb 18th, 2020 - Dysregulation of the immune response to bacterial infection can lead to sepsis, a condition with high mortality. Multiple whole-blood gene-expression studies have defined sepsis-associated molecular signatures, but have not resolved changes in tra...

The role of type 1 interferons in coagulation induced by gram-negative bacteria.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118812
Blood Yang X, Cheng X et. al.

Feb 5th, 2020 - Bacterial infection not only stimulates innate immune responses but also activates coagulation cascades. Overactivation of the coagulation system in bacterial sepsis leads to disseminated intravascular coagulation (DIC), a life-threatening conditi...

Management of HIV-infected patients in the intensive care unit.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7095039
Intensive Care Medicine; Barbier F, Mer M et. al.

Feb 5th, 2020 - The widespread use of combination antiretroviral therapies (cART) has converted the prognosis of HIV infection from a rapidly progressive and ultimately fatal disease to a chronic condition with limited impact on life expectancy. Yet, HIV-infected...

PCR for the detection of pathogens in neonatal early onset sepsis.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6980546
PloS One; Oeser C, Pond M et. al.

Jan 24th, 2020 - A large proportion of neonates are treated for presumed bacterial sepsis with broad spectrum antibiotics even though their blood cultures subsequently show no growth. This study aimed to investigate PCR-based methods to identify pathogens not dete...

see more →

News  37 results

Samsung Bioepis Humira Biosimilar Wins FDA Approval
https://www.medscape.com/viewarticle/915994

Jul 25th, 2019 - (Reuters) - The U.S. Food and Drug Administration approved Samsung Bioepis Co Ltd's biosimilar to AbbVie Inc's blockbuster rheumatoid arthritis treatment Humira, the health agency said on Tuesday. The drug, Hadlima, was developed by South Korea's ...

Merck's Biosimilar to AbbVie's Humira Wins FDA Approval
https://www.medscape.com/viewarticle/915971

Jul 23rd, 2019 - (Reuters) - The U.S. Food and Drug Administration approved Merck & Co Inc's biosimilar to AbbVie Inc's blockbuster rheumatoid arthritis treatment Humira (adalimumab), the health agency said on Tuesday. The drug, Hadlima, is manufactured by Samsung...

Platelet Contamination Leads to 3 Deaths
https://www.mdedge.com/fedprac/article/171390/mixed-topics/platelet-contamination-leads-3-deaths
Jan Dyer

Aug 15th, 2018 - Platelet-transmitted bacterial infections persist as a cause of transfusion-associated morbidity and mortality, according to researchers writing in Mortality and Morbidity Weekly Report. They describe 2 separate clusters of platelet transfusion-a.

Whole blood PCR improves diagnosis of pediatric bacterial sepsis
https://www.mdedge.com/familymedicine/article/140453/infectious-diseases/whole-blood-pcr-improves-diagnosis-pediatric
Pediatric News; Bruce Jancin

Jun 14th, 2017 - MADRID – Whole blood multiplex polymerase chain reaction (PCR) holds considerable promise as a rapid noninvasive test to improve diagnosis of life-threatening bacterial infections in children with suspected sepsis yet negative blood cultures, Clar.

Kids and Flu: How Common Are Complications, Really?
https://www.medscape.com/viewarticle/832632

Oct 2nd, 2014 - Influenza in Children Influenza in children differs in a few essential ways from influenza in adults, starting with the rate of infection from influenza viruses, which is highest in children. The characteristic symptoms—fever, nonproductive cough,...

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