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About 20,368 results

ALLMedicine™ Septic Shock Center

Research & Reviews  9,905 results

Clinical outcomes of continuous vs intermittent meropenem infusion for the treatment of...
https://doi.org/10.17219/acem/121934
Advances in Clinical and Experimental Medicine : Official Organ Wroclaw Medical University; Chen P, Chen F et. al.

Aug 11th, 2020 - The antibiotic meropenem is commonly administered to patients with sepsis and septic shock. The aim of this study was to conduct a meta-analysis to evaluate the clinical efficacy and safety of continuous compared to intermittent meropenem infusion...

PDK1/mTOR Signaling in Myeloid Cells Differentially Regulates the Early and Late Stages...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397376
Mediators of Inflammation; Du J, Li G et. al.

Aug 10th, 2020 - The cecal ligation and perforation (CLP) model is the gold standard for the polymicrobial sepsis. In the CLP mice, the myeloid cells play an important role in septic shock. The phenotypes and the activation state of the macrophage and neutrophil c...

Changes in perfusion can detect changes in the cardiac index in patients with septic sh...
https://doi.org/10.1177/0300060520931675
The Journal of International Medical Research; Lian H, Wang X et. al.

Aug 10th, 2020 - The perfusion index (PI) is usually used to assess peripheral perfusion, which can be influenced by the cardiac index (CI). CI monitoring is often needed during the treatment of patients with shock. We investigated the relationship between changes...

Evaluation of Disseminated Intravascular Coagulation in Critically Ill Pediatric Hemato...
https://doi.org/10.1055/s-0040-1714737
Thrombosis and Haemostasis; Jhang WK, Park SJ

Aug 8th, 2020 - Disseminated intravascular coagulation (DIC) is a serious complication in septic shock. This study aimed to evaluate DIC and associated clinical outcomes using the International Society on Thrombosis and Hemostasis (ISTH) and modified ISTH overt D...

Timing of norepinephrine initiation in patients with septic shock: a systematic review ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409707
Critical Care (London, England); Li Y, Li H et. al.

Aug 8th, 2020 - The effect of the timing of norepinephrine initiation on clinical outcomes in patients with septic shock is uncertain. A systematic review and meta-analysis was performed to evaluate the impact of early and late start of norepinephrine support on ...

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Guidelines  31 results

Blood Purification and Mortality in Sepsis and Septic Shock: A Systematic Review and Meta-analysis of Randomized Trials
https://anesthesiology.pubs.asahq.org/article.aspx?articleid=2737141&resultClick=3
Anesthesiology Putzu,A.,et akl

Jun 26th, 2019 - Background: Sepsis and septic shock are severe inflammatory conditions related to high morbidity and mortality. We performed a systematic review with meta-analysis of randomized trials to assess whether extracorporeal blood purification reduces mo...

The Use of qSOFA in the Emergency Department
https://www.aaem.org/UserFiles/UseofqSOFAintheED.pdf

Apr 7th, 2019 - The quick Sequential Organ Failure Assessment (qSOFA) tool performs poorly in comparison to Systemic Inflammatory Response Syndrome (SIRS) as a diagnostic tool for Emergency Department (ED) patients who may have sepsis or septic shock. However, qS...

Bacteremia - StatPearls
https://www.ncbi.nlm.nih.gov/books/NBK441979/

Nov 14th, 2018 - Bacteremia in the strictest sense refers to viable bacteria in the blood. Asymptomatic bacteremia can occur in normal daily activities such as conducting oral hygiene and after minor medical procedures. In a healthy person, these clinically benign...

Sepsis and Septic Shock - Merck Manuals Professional Edition
https://www.merckmanuals.com/professional/critical-care-medicine/sepsis-and-septic-shock/sepsis-and-septic-shock

Jan 31st, 2018 - Sepsis is a clinical syndrome of life-threatening organ dysfunction caused by a dysregulated response to infection. In septic shock, there is critical reduction in tissue perfusion; acute failure of multiple organs, including the lungs, kidneys, a...

The American College of Critical Care Medicine Clinical Practice Parameters for Hemodyn...
https://doi.org/10.1097/PCC.0000000000001259
Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies; Davis AL, Carcillo JA et. al.

Jul 20th, 2017 - The American College of Critical Care Medicine Clinical Practice Parameters for Hemodynamic Support of Pediatric and Neonatal Septic Shock: Executive Summary.|2017|Davis AL,Carcillo JA,Aneja RK,Deymann AJ,Lin JC,|methods,physiology,methods,therapy,

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Drugs  115 results see all →

Clinicaltrials.gov  10,099 results

Clinical outcomes of continuous vs intermittent meropenem infusion for the treatment of...
https://doi.org/10.17219/acem/121934
Advances in Clinical and Experimental Medicine : Official Organ Wroclaw Medical University; Chen P, Chen F et. al.

Aug 11th, 2020 - The antibiotic meropenem is commonly administered to patients with sepsis and septic shock. The aim of this study was to conduct a meta-analysis to evaluate the clinical efficacy and safety of continuous compared to intermittent meropenem infusion...

PDK1/mTOR Signaling in Myeloid Cells Differentially Regulates the Early and Late Stages...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397376
Mediators of Inflammation; Du J, Li G et. al.

Aug 10th, 2020 - The cecal ligation and perforation (CLP) model is the gold standard for the polymicrobial sepsis. In the CLP mice, the myeloid cells play an important role in septic shock. The phenotypes and the activation state of the macrophage and neutrophil c...

Changes in perfusion can detect changes in the cardiac index in patients with septic sh...
https://doi.org/10.1177/0300060520931675
The Journal of International Medical Research; Lian H, Wang X et. al.

Aug 10th, 2020 - The perfusion index (PI) is usually used to assess peripheral perfusion, which can be influenced by the cardiac index (CI). CI monitoring is often needed during the treatment of patients with shock. We investigated the relationship between changes...

Evaluation of Disseminated Intravascular Coagulation in Critically Ill Pediatric Hemato...
https://doi.org/10.1055/s-0040-1714737
Thrombosis and Haemostasis; Jhang WK, Park SJ

Aug 8th, 2020 - Disseminated intravascular coagulation (DIC) is a serious complication in septic shock. This study aimed to evaluate DIC and associated clinical outcomes using the International Society on Thrombosis and Hemostasis (ISTH) and modified ISTH overt D...

Timing of norepinephrine initiation in patients with septic shock: a systematic review ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409707
Critical Care (London, England); Li Y, Li H et. al.

Aug 8th, 2020 - The effect of the timing of norepinephrine initiation on clinical outcomes in patients with septic shock is uncertain. A systematic review and meta-analysis was performed to evaluate the impact of early and late start of norepinephrine support on ...

see more →

News  211 results

Contrasting qSOFA and SIRS Criteria for Early Sepsis Identification in a Veteran Population
https://www.mdedge.com/fedprac/article/196202/hospital-medicine/contrasting-qsofa-and-sirs-criteria-early-sepsis/page/0/1?channel=327

Mar 1st, 2020 - Sepsis and Septic Shock Assessment Tools As outlined in the Sepsis-3 guidelines, sepsis was defined as suspected or confirmed infection with an acute change in the SOFA score of ≥ 2 points, which is assumed to be 0 in those not known to have preex.

Blood Purification and Mortality in Sepsis and Septic Shock: A Systematic Review and Meta-analysis of Randomized Trials
https://anesthesiology.pubs.asahq.org/article.aspx?articleid=2737141&resultClick=3
Anesthesiology Putzu,A.,et akl

Jun 26th, 2019 - Background: Sepsis and septic shock are severe inflammatory conditions related to high morbidity and mortality. We performed a systematic review with meta-analysis of randomized trials to assess whether extracorporeal blood purification reduces mo...

What’s new in pediatric sepsis
https://www.mdedge.com/jcomjournal/article/203587/infectious-diseases/whats-new-pediatric-sepsis/page/0/1?channel=325

Jun 26th, 2019 - The current Pediatric Sepsis Consensus Conference definition dates back to 2005. A comprehensive revision is getting underway.

The Use of qSOFA in the Emergency Department
https://www.aaem.org/UserFiles/UseofqSOFAintheED.pdf

Apr 7th, 2019 - The quick Sequential Organ Failure Assessment (qSOFA) tool performs poorly in comparison to Systemic Inflammatory Response Syndrome (SIRS) as a diagnostic tool for Emergency Department (ED) patients who may have sepsis or septic shock. However, qS...

Peripheral perfusion fails septic shock test, but optimism remains
https://www.mdedge.com/internalmedicine/article/195129/critical-care/peripheral-perfusion-fails-septic-shock-test-optimism?channel=39313
Jim Kling

Feb 25th, 2019 - SAN DIEGO – During resuscitation of patients with septic shock, a simple strategy of timing the refilling of peripheral capillaries trended toward better 28-day survival than using lactate level targeting, but missed statistical significance. Jim.

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Patient Education  7 results see all →