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About 22,598 results

ALLMedicine™ Septic Shock Center

Research & Reviews  10,643 results

Lipocalin 10 as a New Prognostic Biomarker in Sepsis-Induced Myocardial Dysfunction and...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166480
Mediators of Inflammation; Wang L, Xie W et. al.

Jun 14th, 2021 - Sepsis-induced myocardial dysfunction (SIMD) is the most common complications of sepsis and septic shock with extremely high incidence and mortality. Lipocalin 10 (Lcn10) has recently been identified as a potential biomarker for heart failure, yet...

Antimicrobial Dose Reduction in Continuous Renal Replacement Therapy: Myth or Real Need...
https://doi.org/10.1007/s40262-021-01040-y 10.1007/s00134-017-4755-7 10.1097/01.ASN.0000059863.48590.E9 10.1001/jama.294.7.813 10.1128/AAC.00583-19 10.3389/fphar.2020.00786 10.1177/1060028019865873 10.1016/j.diagmicrobio.2015.01.013 10.1016/j.coph.2015.07.003 10.1093/cid/ciaa224 10.1001/jama.2016.11764 10.3390/microorganisms8020191 10.1128/CMR.00115-20 10.1128/CMR.00079-17 10.1080/17512433.2021.1901574 10.1093/ofid/ofaa139 10.1016/j.ijantimicag.2018.11.001 10.1007/s40262-019-00791-z 10.1186/s13054-019-2378-9 10.1128/AAC.04955-14 10.1128/AAC.02260-20 10.1080/14787210.2020.1756775 10.1128/AAC.01655-19 10.1002/phar.2502 10.1093/jac/dkl251 10.1128/AAC.02608-15 10.1016/j.ijantimicag.2016.06.005 10.1128/AAC.01782-19 10.1186/s13054-019-2434-5 10.1016/j.jgar.2020.03.003 10.1002/phar.1744 10.1002/phar.2338 10.1093/jac/dkz103 10.1007/s00228-018-2535-0 10.1097/FTD.0000000000000729 10.1186/cc10441 10.1007/s10096-021-04181-x 10.1128/AAC.01375-20 10.1136/ejhpharm-2017-001221 10.1093/cid/ciz828 10.1007/s40262-021-00986-3 10.1080/17425255.2020.1750597 10.1186/cc10257 10.2165/00003088-200746120-00003 10.1159/000170103 10.2165/00003495-200868050-00006 10.1016/j.bpa.2003.09.002 10.1016/j.ijantimicag.2017.03.018 10.1128/AAC.02029-20 10.1093/jac/dkaa416 10.1097/CCM.0000000000000317 10.1186/s13054-015-0818-8 10.1159/000455897 10.1159/000316685 10.1159/000501632 10.1186/s13054-019-2692-2 10.1186/s13054-019-2724-y 10.1093/jac/dkv503 10.1186/cc7774 10.1016/S1473-3099(14)70036-2 10.1128/AAC.00712-15 10.1016/j.ijantimicag.2018.10.006 10.1186/1471-2369-14-250 10.1016/j.ijantimicag.2017.01.009 10.1097/CCM.0b013e318241e553 10.1517/17425255.2014.972932 10.1007/s40262-018-0705-y 10.1002/phar.1609 10.1007/s40262-016-0418-z 10.1080/23744235.2017.1296968 10.1016/j.ijantimicag.2009.08.013 10.1007/s40265-017-0851-9
Clinical Pharmacokinetics; Gatti M, Pea F

Jun 14th, 2021 - Acute kidney injury represents a common complication in critically ill patients affected by septic shock and in many cases continuous renal replacement therapy (CRRT) may be required. In this scenario, antimicrobial dose optimization is highly cha...

Predictive value of change in effective arterial elastance in norepinephrine weaning: a...
https://doi.org/10.21037/apm-21-482
Annals of Palliative Medicine; Yang T, Jiang W et. al.

Jun 13th, 2021 - The weaning of vasopressors is usually an empirical choice made by clinicians. The aim of this study is to assess the predictive value of change in effective arterial elastance (ΔEa%) induced by fluid administration in early initiation of norepine...

High pyocyanin production and non-motility of Pseudomonas aeruginosa isolates are corre...
https://doi.org/10.1371/journal.pone.0253259
PloS One; Gupte A, Jyot J et. al.

Jun 11th, 2021 - Studies of the outcome of Pseudomonas aeruginosa bacteremia (Pab) have focused mainly on antibiotic appropriateness. However, P. aeruginosa possesses many virulence factors whose roles in outcomes have not been examined in humans, except for the t...

Leukocyte kinetics during the early stage acts as a prognostic marker in patients with ...
https://doi.org/10.1097/MD.0000000000026288
Medicine Li Q, Xie J et. al.

Jun 11th, 2021 - The leukocytes play an important role in immune function during sepsis. We performed a retrospective study to investigate if leukocytes kinetics was associated with survival in critically ill patients with septic shock in intensive care unit (ICU)...

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Guidelines  33 results

Executive Summary: Surviving Sepsis Campaign International Guidelines for the Managemen...
https://doi.org/10.1097/PCC.0000000000002197
Pediatric Critical Care Medicine : a Journal of the Socie... Weiss SL, Peters MJ et. al.

Feb 7th, 2020 - Executive Summary: Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children.|2020|Weiss SL,Peters MJ,Alhazzani W,Agus MSD,Flori HR,|therapeutic use,standards,methods,...

Blood Purification and Mortality in Sepsis and Septic Shock: A Systematic Review and Meta-analysis of Randomized Trials
https://anesthesiology.pubs.asahq.org/article.aspx?articleid=2737141&resultClick=3
Anesthesiology Putzu,A.,et akl

Jun 26th, 2019 - Background: Sepsis and septic shock are severe inflammatory conditions related to high morbidity and mortality. We performed a systematic review with meta-analysis of randomized trials to assess whether extracorporeal blood purification reduces mo...

The Use of qSOFA in the Emergency Department
https://www.aaem.org/UserFiles/UseofqSOFAintheED.pdf

Apr 7th, 2019 - The quick Sequential Organ Failure Assessment (qSOFA) tool performs poorly in comparison to Systemic Inflammatory Response Syndrome (SIRS) as a diagnostic tool for Emergency Department (ED) patients who may have sepsis or septic shock. However, qS...

Bacteremia - StatPearls
https://www.ncbi.nlm.nih.gov/books/NBK441979/

Nov 14th, 2018 - Bacteremia in the strictest sense refers to viable bacteria in the blood. Asymptomatic bacteremia can occur in normal daily activities such as conducting oral hygiene and after minor medical procedures. In a healthy person, these clinically benign...

Sepsis and Septic Shock - Merck Manuals Professional Edition
https://www.merckmanuals.com/professional/critical-care-medicine/sepsis-and-septic-shock/sepsis-and-septic-shock

Jan 31st, 2018 - Sepsis is a clinical syndrome of life-threatening organ dysfunction caused by a dysregulated response to infection. In septic shock, there is critical reduction in tissue perfusion; acute failure of multiple organs, including the lungs, kidneys, a...

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Drugs  151 results see all →

Clinicaltrials.gov  11,213 results

Lipocalin 10 as a New Prognostic Biomarker in Sepsis-Induced Myocardial Dysfunction and...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166480
Mediators of Inflammation; Wang L, Xie W et. al.

Jun 14th, 2021 - Sepsis-induced myocardial dysfunction (SIMD) is the most common complications of sepsis and septic shock with extremely high incidence and mortality. Lipocalin 10 (Lcn10) has recently been identified as a potential biomarker for heart failure, yet...

Antimicrobial Dose Reduction in Continuous Renal Replacement Therapy: Myth or Real Need...
https://doi.org/10.1007/s40262-021-01040-y 10.1007/s00134-017-4755-7 10.1097/01.ASN.0000059863.48590.E9 10.1001/jama.294.7.813 10.1128/AAC.00583-19 10.3389/fphar.2020.00786 10.1177/1060028019865873 10.1016/j.diagmicrobio.2015.01.013 10.1016/j.coph.2015.07.003 10.1093/cid/ciaa224 10.1001/jama.2016.11764 10.3390/microorganisms8020191 10.1128/CMR.00115-20 10.1128/CMR.00079-17 10.1080/17512433.2021.1901574 10.1093/ofid/ofaa139 10.1016/j.ijantimicag.2018.11.001 10.1007/s40262-019-00791-z 10.1186/s13054-019-2378-9 10.1128/AAC.04955-14 10.1128/AAC.02260-20 10.1080/14787210.2020.1756775 10.1128/AAC.01655-19 10.1002/phar.2502 10.1093/jac/dkl251 10.1128/AAC.02608-15 10.1016/j.ijantimicag.2016.06.005 10.1128/AAC.01782-19 10.1186/s13054-019-2434-5 10.1016/j.jgar.2020.03.003 10.1002/phar.1744 10.1002/phar.2338 10.1093/jac/dkz103 10.1007/s00228-018-2535-0 10.1097/FTD.0000000000000729 10.1186/cc10441 10.1007/s10096-021-04181-x 10.1128/AAC.01375-20 10.1136/ejhpharm-2017-001221 10.1093/cid/ciz828 10.1007/s40262-021-00986-3 10.1080/17425255.2020.1750597 10.1186/cc10257 10.2165/00003088-200746120-00003 10.1159/000170103 10.2165/00003495-200868050-00006 10.1016/j.bpa.2003.09.002 10.1016/j.ijantimicag.2017.03.018 10.1128/AAC.02029-20 10.1093/jac/dkaa416 10.1097/CCM.0000000000000317 10.1186/s13054-015-0818-8 10.1159/000455897 10.1159/000316685 10.1159/000501632 10.1186/s13054-019-2692-2 10.1186/s13054-019-2724-y 10.1093/jac/dkv503 10.1186/cc7774 10.1016/S1473-3099(14)70036-2 10.1128/AAC.00712-15 10.1016/j.ijantimicag.2018.10.006 10.1186/1471-2369-14-250 10.1016/j.ijantimicag.2017.01.009 10.1097/CCM.0b013e318241e553 10.1517/17425255.2014.972932 10.1007/s40262-018-0705-y 10.1002/phar.1609 10.1007/s40262-016-0418-z 10.1080/23744235.2017.1296968 10.1016/j.ijantimicag.2009.08.013 10.1007/s40265-017-0851-9
Clinical Pharmacokinetics; Gatti M, Pea F

Jun 14th, 2021 - Acute kidney injury represents a common complication in critically ill patients affected by septic shock and in many cases continuous renal replacement therapy (CRRT) may be required. In this scenario, antimicrobial dose optimization is highly cha...

Predictive value of change in effective arterial elastance in norepinephrine weaning: a...
https://doi.org/10.21037/apm-21-482
Annals of Palliative Medicine; Yang T, Jiang W et. al.

Jun 13th, 2021 - The weaning of vasopressors is usually an empirical choice made by clinicians. The aim of this study is to assess the predictive value of change in effective arterial elastance (ΔEa%) induced by fluid administration in early initiation of norepine...

High pyocyanin production and non-motility of Pseudomonas aeruginosa isolates are corre...
https://doi.org/10.1371/journal.pone.0253259
PloS One; Gupte A, Jyot J et. al.

Jun 11th, 2021 - Studies of the outcome of Pseudomonas aeruginosa bacteremia (Pab) have focused mainly on antibiotic appropriateness. However, P. aeruginosa possesses many virulence factors whose roles in outcomes have not been examined in humans, except for the t...

Leukocyte kinetics during the early stage acts as a prognostic marker in patients with ...
https://doi.org/10.1097/MD.0000000000026288
Medicine Li Q, Xie J et. al.

Jun 11th, 2021 - The leukocytes play an important role in immune function during sepsis. We performed a retrospective study to investigate if leukocytes kinetics was associated with survival in critically ill patients with septic shock in intensive care unit (ICU)...

see more →

News  553 results

Solutions for Diabetic Ketoacidosis: Finding the Right Balance
https://www.staging.medscape.com/viewarticle/938029

Oct 1st, 2020 - Recent studies have shown improved renal outcomes in adult patients with sepsis receiving balanced solutions instead of "normal" saline. For years, it has been known that 0.9% saline (colloquially referred to as "abnormal saline") can cause a hype...

Solutions for Diabetic Ketoacidosis: Finding the Right Balance
https://www.medscape.com/viewarticle/938029

Oct 1st, 2020 - Recent studies have shown improved renal outcomes in adult patients with sepsis receiving balanced solutions instead of "normal" saline. For years, it has been known that 0.9% saline (colloquially referred to as "abnormal saline") can cause a hype...

9/11 Survivor: 'COVID Humbled Me'
https://www.medscape.com/viewarticle/937238

Sep 10th, 2020 - Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. 9/11 survivor John Feal's foot was crushed by a steel beam, which led to gangrene, septic shock, and partial amputation. But it's the mental trauma that has been...

Fast Five Quiz: Sepsis Key Aspects
https://reference.staging.medscape.com/viewarticle/932124_5

Jun 16th, 2020 - Multiple clinical, laboratory, radiologic, and microbiological data are required for the diagnosis of sepsis and septic shock. Sepsis cannot be diagnosed on the basis of a single abnormality. However, the diagnosis is often made empirically at the...

Key Drugs Join PPEs on List of Front-Line Shortages
https://www.staging.medscape.com/viewarticle/928039

Apr 1st, 2020 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's  Coronavirus Resource Center. First it was a critical shortage of personal protective equipment. Then pleas for more ventilators to sustain patients with COVID-19 and provider...

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Patient Education  5 results see all →