ALLMedicine™ Bacterial Pneumonia Center

Nov 15th, 2022 - IL-38, a recently discovered cytokine of IL-1 family, exerts immunoregulatory activities in multi-type inflammatory diseases. However, its expression level and underlying clinical importance for IL-38 in respiratory bacterial infections remain unk...

Nov 14th, 2022 - Procalcitonin (PCT) is an inflammatory marker elevated in bacteremia and bacterial pneumonia. We aimed to assess the real-world diagnostic accuracy of PCT in hospitalized patients with malignancy. A retrospective cohort of 715 patients with cancer...

Nov 10th, 2022 - Streptococcus pneumoniae persists as a leading cause of bacterial pneumonia despite the widespread use of polysaccharide-based vaccines. The limited serotype coverage of current vaccines has led to increased incidence of nonvaccine serotypes, as w...

Nov 5th, 2022 - To describe the natural course of procalcitonin (PCT) in patients with coronavirus disease 2019 (COVID-19) and the correlation between PCT and antimicrobial prescribing to provide insight into best practices for PCT data utilization in antimicrobi...

Oct 28th, 2022 - The global health crisis due to the fast spread of coronavirus disease (Covid-19) has caused great danger to all aspects of healthcare, economy, and other aspects. The highly infectious and insidious nature of the new coronavirus greatly increases...

Sep 16th, 2022 - The primary purpose of this study is to evaluate the safety and tolerability of imipenem/cilastatin/relebactam (IMI/REL) in participants from birth to less than 18 years of age with confirmed or suspected gram-negative bacterial infection. Partici...

Aug 4th, 2022 - Pneumonia is the most common infectious cause of mortality in older adults. Standard practice for older adults with pneumonia involves hospitalization and antibiotics. However, recent studies suggest that a significant portion of suspected communi...

Jul 20th, 2022 - This study will evaluate the efficacy and safety of imipenem/cilastatin/relebactam (IMI/REL) (MK-7655A) compared to piperacillin/tazobactam (PIP/TAZ) in the treatment of adults diagnosed with Hospital-Acquired Bacterial Pneumonia (HABP) or Ventila...

Jun 21st, 2022 - In patients with positive airway sample for respiratory viruses, the investigators hypothesize that discontinuation of antibiotic therapy is safe and non-inferior to continuation of antibiotic therapy. More specifically, the investigators hypothes...

May 31st, 2022 - Clinical pneumonia is a leading cause of pediatric hospitalization. The etiology is generally bacterial or viral. Prompt and optimal treatment of pneumonia is critical to reduce mortality. However, adequate pneumonia management is hampered by: a) ...

Oct 25th, 2022 - In early October, respiratory syncytial virus, or RSV, tore through Victoria Thiele's Indiana home. Her three older children had manageable symptoms. But her 8-week-old newborn ended up developing a severe case. Thiele, whose family lives in Fort ...

Oct 21st, 2022 - Patients with iron deficiency anemia who developed bacterial pneumonia showed improved outcomes compared to those without iron deficiency anemia, based on data from more than 450,000 individuals in the National Inpatient Sample. Iron deficiency is...

Aug 4th, 2022 - Findings from a phase 1b trial (NCT02537613) showed that the addition of obinutuzumab (Gazyva) to ibrutinib (Imbruvica) produced a complete response (CR) rate that compared favorably with what has historically been observed with ibrutinib monother...

Jul 26th, 2022 - In the spring of 2022, the Pediatric Academic Society meeting sponsored an informative "Hot Topic" session reviewing practitioner dilemmas when diagnosing and treating community-acquired pneumonia (CAP). The CAP Diagnosis One of the first challeng...

Jun 27th, 2022 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. COVID-19 has been associated with a threefold increased risk of Alzheimer's disease (AD) and a doubling of Parkinson's disease (PD) risk, a new st...