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About 13,860 results

ALLMedicine™ Septic Shock Center

Research & Reviews  4,628 results

Endothelial-Dependent Responses Correlate with Pediatric SOFA Scores During Severe Seps...
https://doi.org/10.1007/s12265-021-10202-z 10.5114/amsad.2019.86754 10.1097/PCC.0000000000002049 10.1097/00024382-200303000-00013 10.1016/j.atherosclerosis.2007.07.009
Journal of Cardiovascular Translational Research; Stark RJ

Jan 19th, 2022 - Sepsis is an exaggerated host response to an infectious challenge that is associated with significant alterations in vasomotor tone. We hypothesized that the endothelial dysfunction observed during severe sepsis and septic shock would correlate wi...

Construction and Validation of a Risk Prediction Model for Acute Kidney Injury in Patie...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758295
Disease Markers; Yue S, Li S et. al.

Jan 18th, 2022 - Acute kidney injury (AKI) is an important complication in critically ill patients, especially in sepsis and septic shock patients. Early prediction of AKI in septic shock can provide clinicians with sufficient information for timely intervention s...

Sugemalimab versus placebo, in combination with platinum-based chemotherapy, as first-l...
https://doi.org/10.1016/S1470-2045(21)00650-1
The Lancet. Oncology; Zhou C, Wang Z et. al.

Jan 18th, 2022 - PD-1 inhibitor plus chemotherapy had been shown to be an effective first-line treatment for patients with metastatic non-small-cell lung cancer (NSCLC). However, there was no robust evidence showing a PD-L1 inhibitor combined with chemotherapy ben...

Differential Diagnosis of Motor Weakness in Bilateral Lower Extremities Developed durin...
https://doi.org/10.1097/PHM.0000000000001950
American Journal of Physical Medicine & Rehabilitation; Kang MS, Boudier-Revéret M et. al.

Jan 17th, 2022 - Differential Diagnosis of Motor Weakness in Bilateral Lower Extremities Developed during Treatment of Septic Shock due to Urinary Tract Infection.|2022|Kang MS,Boudier-Revéret M,Chang MC,|

Central Venous-to-Arterial CO2 Difference-Assisted Goal-Directed Hemodynamic Management...
https://doi.org/10.1213/ANE.0000000000005833 10.1097/ana.0000000000000769
Anesthesia and Analgesia; H N LK, Tripathy S et. al.

Jan 15th, 2022 - Different goals have guided goal-directed therapy (GDT). Protocols aiming for central venous-to-arterial carbon dioxide gap (DCO2) <6 mm Hg have improved organ function in septic shock. Evidence for use of DCO2 in the perioperative period is scarc...

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Guidelines  10 results

COVID-19 PICU guidelines: for high- and limited-resource settings.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577838
Pediatric Research; Kache S, Chisti MJ et. al.

Jul 8th, 2020 - Fewer children than adults have been affected by the COVID-19 pandemic, and the clinical manifestations are distinct from those of adults. Some children particularly those with acute or chronic co-morbidities are likely to develop critical illness...

Executive Summary: Surviving Sepsis Campaign International Guidelines for the Managemen...
https://doi.org/10.1097/PCC.0000000000002197
Pediatric Critical Care Medicine : a Journal of the Socie... Weiss SL, Peters MJ et. al.

Feb 8th, 2020 - Executive Summary: Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children.|2020|Weiss SL,Peters MJ,Alhazzani W,Agus MSD,Flori HR,|therapeutic use,standards,methods,...

Endoscopic management of common bile duct stones: European Society of Gastrointestinal ...
https://doi.org/10.1055/a-0862-0346
Endoscopy Manes G, Paspatis G et. al.

Apr 4th, 2019 - ESGE recommends offering stone extraction to all patients with common bile duct stones, symptomatic or not, who are fit enough to tolerate the intervention.Strong recommendation, low quality evidence.ESGE recommends liver function tests and abdomi...

The American College of Critical Care Medicine Clinical Practice Parameters for Hemodyn...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341147
Pediatric Critical Care Medicine : a Journal of the Socie... Davis AL, Carcillo JA et. al.

Jul 21st, 2017 - The American College of Critical Care Medicine Clinical Practice Parameters for Hemodynamic Support of Pediatric and Neonatal Septic Shock: Executive Summary.|2017|Davis AL,Carcillo JA,Aneja RK,Deymann AJ,Lin JC,|methods,physiology,methods,therapy,

Task force on management and prevention of Acinetobacter baumannii infections in the ICU.
https://doi.org/10.1007/s00134-015-4079-4
Intensive Care Medicine; Garnacho-Montero J, Dimopoulos G et. al.

Oct 7th, 2015 - Acinetobacter baumannii constitutes a dreadful problem in many ICUs worldwide. The very limited therapeutic options available for these organisms are a matter of great concern. No specific guidelines exist addressing the prevention and management ...

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Drugs  91 results see all →

Clinicaltrials.gov  346 results

Vitamin C, Hydrocortisone and Thiamine in Patients With Septic Shock
https://clinicaltrials.gov/ct2/show/NCT05192213

Jan 14th, 2022 - The global burden of sepsis is substantial with an estimated 15 to 19 million cases per year, most occurring in low-income countries. With recent advances in diagnosis and supportive treatment, the 28-day mortality from sepsis in high-income count...

Velocity Time Integral vs PICCO for Evaluation of Passive Leg Raising in Septic Shock
https://clinicaltrials.gov/ct2/show/NCT03621449

Jan 11th, 2022 - One method to predict fluid responsiveness is to increase preload by transferring blood from the lower extremities to the central compartment through a passive leg raising (PLR) maneuver and then measure the resulting change in cardiac output. It ...

Implementation Trial of Predictive Modeling to Enhance Diagnosis and Improve Treatment in Pediatric Septic Shock
https://clinicaltrials.gov/ct2/show/NCT05065333

Jan 11th, 2022 - Septic shock is a leading global cause of pediatric death. In the US, the in-hospital mortality rate for children with sepsis is 5-20%. Septic shock is a state of critical infection that requires advanced and resource-intensive resuscitation, and ...

Restrictive Fluid Administration vs. Standard of Care in Emergency Department Sepsis Patients
https://clinicaltrials.gov/ct2/show/NCT05076435

Jan 6th, 2022 - BACKGROUND: Sepsis is common in emergency department (ED) patients. Traditionally, intravenous (IV) fluids are used to optimise the circulation, and the use of higher volumes is recommended by international guidelines, but there are no recommendat...

Early Vasopressors in Sepsis
https://clinicaltrials.gov/ct2/show/NCT05179499

Jan 5th, 2022 - Sepsis results from overwhelming reactions to microbial infections where the immune system initiates dysregulated responses that lead to remote organ dysfunction, shock and ultimately death. Sepsis remains a significant global issue - as well as d...

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News  461 results

Enfortumab Vedotin Approaches EU Approval for Locally Advanced or Metastatic Urothelial Cancer
https://www.onclive.com/view/enfortumab-vedotin-approaches-eu-approval-for-locally-advanced-or-metastatic-urothelial-cancer

Dec 17th, 2021 - The European Medicines Agency’s Committee for Medicinal Products for Human Use (CHMP) has adopted a positive opinion in favor of the approval of enfortumab vedotin (Padcev) as a monotherapy in the treatment of adult patients with locally advanced ...

Trabectedin Effective in Heavily Pretreated Metastatic Soft Tissue Sarcomas
https://www.onclive.com/view/trabectedin-effective-in-heavily-pretreated-metastatic-soft-tissue-sarcomas

Oct 6th, 2021 - George D. Demetri, MD Trabectedin demonstrated superior disease control compared with dacarbazine in heavily pretreated patients with advanced soft tissue sarcoma, according to findings from a phase III trial published in the Journal of Clinical ...

Struggling With COVID-19 on the Cancer Floor
https://www.onclive.com/view/struggling-with-covid-19-on-the-cancer-floor

Oct 6th, 2021 - Driving through downtown Cleveland on a recent September evening, there is hardly a mask in site. People are strolling down the street, laughing with friends, eating and drinking without a care in the world. For many, the coronavirus disease 2019 ...

Usmani Highlights Impact of Latest Daratumumab Triplet Approval in Lenalidomide-Refractory Myeloma
https://www.onclive.com/view/usmani-highlights-impact-of-latest-daratumumab-triplet-approval-in-lenalidomide-refractory-myeloma

Aug 17th, 2021 - The combination of daratumumab (Darzalex), carfilzomib (Kyprolis), and dexamethasone (KdD) is an important addition to the relapsed/refractory multiple myeloma treatment arsenal, according to Saad Z. Usmani, MD, FACP, who added that this regimen i...

FDA Approval Insights: Daratumumab / Carfilzomib / Dexamethasone in Myeloma
https://www.onclive.com/view/fda-approval-insights-daratumumab-carfilzomib-dexamethasone-in-myeloma

Aug 17th, 2021 - Welcome to OncLive On Air™! I’m your host today, Jessica Hergert. OncLive On Air™ is a podcast from OncLive, which provides oncology professionals with the resources and information they need to provide the best patient care. In both digital an...

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Patient Education  8 results see all →