ALLMedicine™ Acetaminophen Toxicity Center
Research & Reviews 91 results
Liver Transplantation : Official Publication of the Ameri... Wong NZ, Reddy KR et. al.
Jun 3rd, 2021 - The impact of acute liver failure (ALF) etiology on waitlist (WL) and posttransplantation outcomes, independent of severity of illness, is incompletely characterized. All adults (n = 1691) listed for primary liver transplantation (LT) between 2002...
Toxicology Viswanathan P, Gupta P et. al.
May 10th, 2021 - Preterm infants are at greater risk for adverse drug effects due to hepatic immaturity. Multiple interventions during intensive care increases potential for drug interactions. In this setting, high-dose caffeine used for apnea in premature infants...
Psychiatric Services (Washington, D.C.); Shekunov J, Lewis CP et. al.
Apr 23rd, 2021 - Acetaminophen is a common cause of intentional and inadvertent overdoses among children and adolescents worldwide. Little is known about characteristics and clinical outcomes of these youths. The primary goal of this naturalistic study was to desc...
Journal of Medical Toxicology : Official Journal of the A... Baum RA, Woolum JA et. al.
Apr 22nd, 2021 - Acetaminophen is a commonly used analgesic and antipyretic, with the potential to cause significant injury when ingested in toxic amounts. Although the antidote n-acetylcysteine (NAC) is available, evidence supporting dose recommendations for pati...
https://doi.org/10.1097/AOG.0000000000004351 10.1136/bmjopen-2013-004365 10.1016/j.ebiom.2017.10.023 10.1007/s13181-012-0264-9 10.1111/j.1471-05.28.1989.tb02420.x 10.1093/jn/nxaa263 10.1097/00003246-200104000-00036 10.1093/jn/126.11.2823 10.1093/jn/126.11.2813 10.1152/ajpendo.00206.2001 10.1007/s004310051054 10.1186/1750-1172-2-16 10.1016/S0140-6736(08)61398-7 10.1016/0002-9378(86)90173-0 10.1172/jci110853 10.1056/NEJMct0708278 10.1080/08998280.2017.11929570 10.1016/s0890-6238(96)00200-6 10.1016/j.ejogrb.2005.09.007 10.1016/j.jpeds.2015.09.076 10.1067/mob.2003.112 10.1016/s1472-6483(10)60322-7 10.1080/15563650802665587
Obstetrics and Gynecology; Dom AM, Royzer R et. al.
Apr 8th, 2021 - Although acetaminophen is commonly used in pregnancy, it can deplete glutathione concentrations and cause accumulation of 5-oxoproline, with subsequent metabolic acidosis. A malnourished 25-year-old woman, G2P1001, with chronic acetaminophen use p...
Drugs 1 results see all →
Clinicaltrials.gov 3 results
Mar 8th, 2020 - Although ALF is truly an orphan disease affecting only about 2,000 persons per year, its severity, its frequency among young adults, and its high resource utilization justifies the attention paid to it. In addition, ALF has captured the interest a...
Apr 11th, 2012 - It was recently reported that IL-10 is protective in Acetaminophen (APAP) toxicity and it down-regulates iNOS production. In an ongoing Pediatric Pharmacology Research Unit (PPRU) Network study, plasma IL-10 levels were higher in patients that dev...
Combination therapy with peginterferon plus ribavirin has become the current standard of care for chronic hepatitis C (CHC) patients, with an overall sustained virologic response (SVR) rate of 54-63%. Based on the ample evidence, a 48-week course ...
News 12 results
Mar 28th, 2019 - Various treatment protocols for acetaminophen toxicity are available, depending on the institution and the poison control center. For intravenous treatment (used in pregnant women, altered mental status, acetaminophen-induced liver failure, and in...
Jul 25th, 2017 - Acute liver failure (ALF), is a life-threatening deterioration of liver function in people without preexisting cirrhosis. It can be caused by acetaminophen toxicity, pregnancy, ischemia, hepatitis A infection, and Wilson disease, among other thing.
Mar 1st, 2017 - A rapid point-of-care assay for acetaminophen-related liver toxicity had a sensitivity of 100% and a specificity of 86%, compared with etiologic diagnosis, based on the results of a multicenter study published in the April issue of Clinical Gastro.
Nov 12th, 2012 - BOSTON – Acetaminophen toxicity is the most frequent cause of acute liver failure in the United States and its usually milder presentation, along with comorbid psychosocial issues, explain why fewer patients with the etiology undergo liver transpl.
Nov 12th, 2012 - Action Points One of every 15 hospitalized patients treated with acetaminophen -- including many patients with liver disease -- received supratherapeutic doses of the drug. Point out that among patients receiving acetaminophen, more than 20% of pa...