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About 270 results

ALLMedicine™ Acetaminophen Toxicity Center

Research & Reviews  91 results

Acute Liver Failure Etiology Is an Independent Predictor of Waitlist Outcome but Not Po...
https://doi.org/10.1002/lt.26187
Liver Transplantation : Official Publication of the Ameri... Wong NZ, Reddy KR et. al.

Jun 3rd, 2021 - The impact of acute liver failure (ALF) etiology on waitlist (WL) and posttransplantation outcomes, independent of severity of illness, is incompletely characterized. All adults (n = 1691) listed for primary liver transplantation (LT) between 2002...

Caffeine disrupts ataxia telangiectasia mutated gene-related pathways and exacerbates a...
https://doi.org/10.1016/j.tox.2021.152811
Toxicology Viswanathan P, Gupta P et. al.

May 10th, 2021 - Preterm infants are at greater risk for adverse drug effects due to hepatic immaturity. Multiple interventions during intensive care increases potential for drug interactions. In this setting, high-dose caffeine used for apnea in premature infants...

Clinical Characteristics, Outcomes, Disposition, and Acute Care of Children and Adolesc...
https://doi.org/10.1176/appi.ps.202000081
Psychiatric Services (Washington, D.C.); Shekunov J, Lewis CP et. al.

Apr 23rd, 2021 - Acetaminophen is a common cause of intentional and inadvertent overdoses among children and adolescents worldwide. Little is known about characteristics and clinical outcomes of these youths. The primary goal of this naturalistic study was to desc...

Evaluation of Dosing Strategies of N-acetylcysteine for Acetaminophen Toxicity in Patie...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8206426
Journal of Medical Toxicology : Official Journal of the A... Baum RA, Woolum JA et. al.

Apr 22nd, 2021 - Acetaminophen is a commonly used analgesic and antipyretic, with the potential to cause significant injury when ingested in toxic amounts. Although the antidote n-acetylcysteine (NAC) is available, evidence supporting dose recommendations for pati...

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Drugs  1 results see all →

Clinicaltrials.gov  3 results

A Multi-Center Trial to Study Acute Liver Failure in Adults
https://clinicaltrials.gov/ct2/show/NCT00518440

Mar 8th, 2020 - Although ALF is truly an orphan disease affecting only about 2,000 persons per year, its severity, its frequency among young adults, and its high resource utilization justifies the attention paid to it. In addition, ALF has captured the interest a...

Cytokines Polymorphisms and Acetaminophen Toxicity
https://clinicaltrials.gov/ct2/show/NCT00166608

Apr 11th, 2012 - It was recently reported that IL-10 is protective in Acetaminophen (APAP) toxicity and it down-regulates iNOS production. In an ongoing Pediatric Pharmacology Research Unit (PPRU) Network study, plasma IL-10 levels were higher in patients that dev...

Micro RNA-122 and the Clinical Course of Patients With Chronic Hepatitis C
https://clinicaltrials.gov/ct2/show/NCT00980161

Combination therapy with peginterferon plus ribavirin has become the current standard of care for chronic hepatitis C (CHC) patients, with an overall sustained virologic response (SVR) rate of 54-63%. Based on the ample evidence, a 48-week course ...

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News  12 results

Acute Liver Failure in a 64-Year-Old Man
https://reference.medscape.com/viewarticle/911040_5

Mar 28th, 2019 - Various treatment protocols for acetaminophen toxicity are available, depending on the institution and the poison control center. For intravenous treatment (used in pregnant women, altered mental status, acetaminophen-induced liver failure, and in...

Acute liver failure in the ED
https://www.mdedge.com/internalmedicine/article/143261/liver-disease/acute-liver-failure-ed
Jennie Smith

Jul 25th, 2017 - Acute liver failure (ALF), is a life-threatening deterioration of liver function in people without preexisting cirrhosis. It can be caused by acetaminophen toxicity, pregnancy, ischemia, hepatitis A infection, and Wilson disease, among other thing.

VIDEO: Point-of-care assay caught acetaminophen toxicity
https://www.mdedge.com/internalmedicine/article/132476/hepatology/video-point-care-assay-caught-acetaminophen-toxicity
Amy Karon

Mar 1st, 2017 - A rapid point-of-care assay for acetaminophen-related liver toxicity had a sensitivity of 100% and a specificity of 86%, compared with etiologic diagnosis, based on the results of a multicenter study published in the April issue of Clinical Gastro.

Acetaminophen Liver Failure Least Likely to Get Transplant
https://www.mdedge.com/internalmedicine/article/56694/gastroenterology/acetaminophen-liver-failure-least-likely-get
Jeff Evans

Nov 12th, 2012 - BOSTON – Acetaminophen toxicity is the most frequent cause of acute liver failure in the United States and its usually milder presentation, along with comorbid psychosocial issues, explain why fewer patients with the etiology undergo liver transpl.

Excess Tylenol Dosing Common in Hospitals
https://www.medpagetoday.com/hospitalbasedmedicine/generalhospitalpractice/35903

Nov 12th, 2012 - Action Points One of every 15 hospitalized patients treated with acetaminophen -- including many patients with liver disease -- received supratherapeutic doses of the drug. Point out that among patients receiving acetaminophen, more than 20% of pa...

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Patient Education  1 results see all →