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About 117 results

ALLMedicine™ Ammonia Toxicity Center

Research & Reviews  57 results

Ammonia toxicity and its prevention in inherited defects of the urea cycle.
https://doi.org/10.1111/j.1463-1326.2009.01054.x
Diabetes, Obesity & Metabolism; Walker V

Jun 17th, 2009 - The urea cycle is the final pathway for removal of surplus nitrogen from the body, and the major route in humans for detoxification of ammonia. The full complement of enzymes is expressed only in liver. Inherited deficiencies of urea cycle enzymes...

Ammonia induces RNA oxidation in cultured astrocytes and brain in vivo.
https://doi.org/10.1002/hep.22345
Hepatology (Baltimore, Md.); Görg B, Qvartskhava N et. al.

May 28th, 2008 - Oxidative stress plays a major role in cerebral ammonia toxicity and the pathogenesis of hepatic encephalopathy (HE). As shown in this study, ammonia induces a rapid RNA oxidation in cultured rat astrocytes, vital mouse brain slices, and rat brain...

Oxidative stress markers in the brain of patients with cirrhosis and hepatic encephalop...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395472
Hepatology (Baltimore, Md.); Görg B, Qvartskhava N et. al.

Jun 28th, 2010 - Cell culture studies and animal models point to an important role of oxidative/nitrosative stress in the pathogenesis of cerebral ammonia toxicity. However, it is unknown whether oxidative/nitrosative stress in the brain is also characteristic of ...

Interaction of oxidative stress, astrocyte swelling and cerebral ammonia toxicity.
https://doi.org/10.1097/MCO.0b013e328333b829
Current Opinion in Clinical Nutrition and Metabolic Care; Häussinger D, Görg B

Nov 11th, 2009 - Description of the role of oxidative stress in the pathogenesis of cerebral ammonia toxicity and hepatic encephalopathy. Ammonia plays a key role in the pathogenesis of hepatic encephalopathy, which manifests as a neuropsychiatric syndrome accompa...

Microglia activation in hepatic encephalopathy in rats and humans.
https://doi.org/10.1002/hep.24326
Hepatology (Baltimore, Md.); Zemtsova I, Görg B et. al.

Mar 31st, 2011 - Astrocytes play an important role in the pathogenesis of hepatic encephalopathy (HE) and ammonia toxicity, whereas little is known about microglia and neuroinflammation under these conditions. We therefore studied the effects of ammonia on rat mic...

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Drugs  1 results see all →

Clinicaltrials.gov  59 results

Ammonia toxicity and its prevention in inherited defects of the urea cycle.
https://doi.org/10.1111/j.1463-1326.2009.01054.x
Diabetes, Obesity & Metabolism; Walker V

Jun 17th, 2009 - The urea cycle is the final pathway for removal of surplus nitrogen from the body, and the major route in humans for detoxification of ammonia. The full complement of enzymes is expressed only in liver. Inherited deficiencies of urea cycle enzymes...

Ammonia induces RNA oxidation in cultured astrocytes and brain in vivo.
https://doi.org/10.1002/hep.22345
Hepatology (Baltimore, Md.); Görg B, Qvartskhava N et. al.

May 28th, 2008 - Oxidative stress plays a major role in cerebral ammonia toxicity and the pathogenesis of hepatic encephalopathy (HE). As shown in this study, ammonia induces a rapid RNA oxidation in cultured rat astrocytes, vital mouse brain slices, and rat brain...

Oxidative stress markers in the brain of patients with cirrhosis and hepatic encephalop...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395472
Hepatology (Baltimore, Md.); Görg B, Qvartskhava N et. al.

Jun 28th, 2010 - Cell culture studies and animal models point to an important role of oxidative/nitrosative stress in the pathogenesis of cerebral ammonia toxicity. However, it is unknown whether oxidative/nitrosative stress in the brain is also characteristic of ...

Interaction of oxidative stress, astrocyte swelling and cerebral ammonia toxicity.
https://doi.org/10.1097/MCO.0b013e328333b829
Current Opinion in Clinical Nutrition and Metabolic Care; Häussinger D, Görg B

Nov 11th, 2009 - Description of the role of oxidative stress in the pathogenesis of cerebral ammonia toxicity and hepatic encephalopathy. Ammonia plays a key role in the pathogenesis of hepatic encephalopathy, which manifests as a neuropsychiatric syndrome accompa...

Microglia activation in hepatic encephalopathy in rats and humans.
https://doi.org/10.1002/hep.24326
Hepatology (Baltimore, Md.); Zemtsova I, Görg B et. al.

Mar 31st, 2011 - Astrocytes play an important role in the pathogenesis of hepatic encephalopathy (HE) and ammonia toxicity, whereas little is known about microglia and neuroinflammation under these conditions. We therefore studied the effects of ammonia on rat mic...

see more →