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About 169 results

ALLMedicine™ Cocaine Toxicity Center

Research & Reviews  83 results

Reengineering of Albumin-Fused Cocaine Hydrolase CocH1 (TV-1380) to Prolong Its Biologi...
https://doi.org/10.1208/s12248-019-0377-z
The AAPS Journal; Cai Y, Zhou S et. al.

Nov 22nd, 2019 - Therapeutic treatment of cocaine toxicity or addiction is a grand medical challenge. As a promising therapeutic strategy for treatment of cocaine toxicity and addiction to develop a highly efficient cocaine hydrolase (CocH) capable of accelerating...

In vivo characterization of toxicity of norcocaethylene and norcocaine identified as th...
https://doi.org/10.1016/j.drugalcdep.2019.04.033
Drug and Alcohol Dependence; Zheng X, Shang L et. al.

Sep 9th, 2019 - Majority of cocaine users also consume alcohol, and concurrent use of cocaine and alcohol produces cocaethylene, norcocaine, norcocaethylene, and other non-toxic metabolites. It is essential to know their relative toxicity for development of a tru...

Preventative effects of aripiprazole and quetiapine on seizure and lethality in a mice ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726820
The Journal of International Medical Research; Yilmaz A, Erdur B et. al.

Jun 12th, 2019 - Preventative effects of aripiprazole and quetiapine on seizure and lethality in a mice cocaine toxicity model: an experimental study.|2019|Yilmaz A,Erdur B,Ozen M,Sabirli R,Turkcuer I,|toxicity,pharmacology,pharmacology,toxicity,etiology,mortality...

Authors' reply to comment on "Epidemiology, clinical features and management of patient...
https://doi.org/10.1080/15563650.2019.1613549
Clinical Toxicology (Philadelphia, Pa.); Miró Ò, Dargan PI et. al.

May 16th, 2019 - Authors' reply to comment on "Epidemiology, clinical features and management of patients presenting to European emergency departments with acute cocaine toxicity: comparison between powder cocaine and crack cocaine cases".|2019|Miró Ò,Dargan PI,Ga...

Epidemiology, clinical features and management of patients presenting to European emerg...
https://doi.org/10.1080/15563650.2018.1549735
Clinical Toxicology (Philadelphia, Pa.); Miró Ò, Dargan PI et. al.

Jan 30th, 2019 - Objective: To analyse the epidemiology, clinical picture and emergency department (ED) management of a large series of patients who presented to European EDs after cocaine consumption, comparing data from powder (C1 group) and crack (C2 group) con...

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Clinicaltrials.gov  85 results

Reengineering of Albumin-Fused Cocaine Hydrolase CocH1 (TV-1380) to Prolong Its Biologi...
https://doi.org/10.1208/s12248-019-0377-z
The AAPS Journal; Cai Y, Zhou S et. al.

Nov 22nd, 2019 - Therapeutic treatment of cocaine toxicity or addiction is a grand medical challenge. As a promising therapeutic strategy for treatment of cocaine toxicity and addiction to develop a highly efficient cocaine hydrolase (CocH) capable of accelerating...

In vivo characterization of toxicity of norcocaethylene and norcocaine identified as th...
https://doi.org/10.1016/j.drugalcdep.2019.04.033
Drug and Alcohol Dependence; Zheng X, Shang L et. al.

Sep 9th, 2019 - Majority of cocaine users also consume alcohol, and concurrent use of cocaine and alcohol produces cocaethylene, norcocaine, norcocaethylene, and other non-toxic metabolites. It is essential to know their relative toxicity for development of a tru...

Preventative effects of aripiprazole and quetiapine on seizure and lethality in a mice ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726820
The Journal of International Medical Research; Yilmaz A, Erdur B et. al.

Jun 12th, 2019 - Preventative effects of aripiprazole and quetiapine on seizure and lethality in a mice cocaine toxicity model: an experimental study.|2019|Yilmaz A,Erdur B,Ozen M,Sabirli R,Turkcuer I,|toxicity,pharmacology,pharmacology,toxicity,etiology,mortality...

Authors' reply to comment on "Epidemiology, clinical features and management of patient...
https://doi.org/10.1080/15563650.2019.1613549
Clinical Toxicology (Philadelphia, Pa.); Miró Ò, Dargan PI et. al.

May 16th, 2019 - Authors' reply to comment on "Epidemiology, clinical features and management of patients presenting to European emergency departments with acute cocaine toxicity: comparison between powder cocaine and crack cocaine cases".|2019|Miró Ò,Dargan PI,Ga...

Epidemiology, clinical features and management of patients presenting to European emerg...
https://doi.org/10.1080/15563650.2018.1549735
Clinical Toxicology (Philadelphia, Pa.); Miró Ò, Dargan PI et. al.

Jan 30th, 2019 - Objective: To analyse the epidemiology, clinical picture and emergency department (ED) management of a large series of patients who presented to European EDs after cocaine consumption, comparing data from powder (C1 group) and crack (C2 group) con...

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News  1 results

Landmark Resuscitation Study: The FOAMed Report
https://www.medpagetoday.com/emergencymedicine/emergencymedicine/49998

Feb 12th, 2015 - A landmark study is out: PROPPR. It's a randomized trial in JAMA investigating outcomes between 1:1:1 versus 1:1:2 plasma:platelet:pRBC transfusion ratios, and #FOAMed is all atwitter about it. Check out HippoEM's discussion, REBEL EM's (quite lit...

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