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About 146 results

ALLMedicine Cyanide Toxicity Center

Research & Reviews  71 results

Challenging the current paradigm of the chemiosmotic theory for cyanide toxicity.
https://doi.org/10.1016/j.tox.2020.152377
Toxicology Wallace K

Jan 24th, 2020 - Challenging the current paradigm of the chemiosmotic theory for cyanide toxicity.|2020|Wallace K,|

Rebound metabolic acidosis following intentional amygdalin supplement overdose.
https://doi.org/10.1080/15563650.2019.1640369
Clinical Toxicology (Philadelphia, Pa.); Shively RM, Harding SA et. al.

Jul 19th, 2019 - Introduction: Amygdalin, marketed misleadingly as supplement "Vitamin B17," is a cyanogenic glycoside. When swallowed, it is hydrolyzed into cyanide in the small intestine, which causes histotoxic hypoxia via inhibition of cytochrome c oxidase. It...

Efficacy of Oral Administration of Sodium Thiosulfate and Glycine in a Large, Swine Mod...
https://doi.org/10.1016/j.annemergmed.2019.03.023
Annals of Emergency Medicine; Ng PC, Hendry-Hofer TB et. al.

May 13th, 2019 - Cyanide is a deadly poison, particularly with oral exposure, in which larger doses can occur before any symptoms develop. Multiple governmental agencies highlight oral cyanide as an agent that can be used in a terrorist attack because it can be ea...

Intramuscular sodium tetrathionate as an antidote in a clinically relevant swine model ...
https://doi.org/10.1080/15563650.2019.1602272
Clinical Toxicology (Philadelphia, Pa.); Hendry-Hofer TB, Witeof AE et. al.

Apr 21st, 2019 - Cyanide is a metabolic poison used in multiple industries and is a high threat chemical agent. Current antidotes require intravenous administration, limiting their usefulness in a mass casualty scenario. Sodium tetrathionate reacts directly with c...

Iatrogenic pediatric hydroxocobalamin overdose.
https://doi.org/10.1016/j.ajem.2019.04.012
The American Journal of Emergency Medicine; Friedman BT, Chen BC et. al.

Apr 19th, 2019 - Hydroxocobalamin, a precursor molecule to vitamin B12, has emerged as the preferred empiric treatment for patients rescued from enclosed-space fires with concern for inhalational injury and potential concomitant cyanide toxicity. Limited data exis...

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Guidelines  1 results

Empiric management of cyanide toxicity associated with smoke inhalation.
https://doi.org/10.1017/S1049023X11006625
Prehospital and Disaster Medicine; O'Brien DJ, Walsh DW et. al.

Feb 17th, 2012 - Enclosed-space smoke inhalation is the fifth most common cause of all unintentional injury deaths in the United States. Increasingly, cyanide has been recognized as a significant toxicant in many cases of smoke inhalation. However, it cannot be em...

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Drugs  1 results see all →

Clinicaltrials.gov  73 results

Challenging the current paradigm of the chemiosmotic theory for cyanide toxicity.
https://doi.org/10.1016/j.tox.2020.152377
Toxicology Wallace K

Jan 24th, 2020 - Challenging the current paradigm of the chemiosmotic theory for cyanide toxicity.|2020|Wallace K,|

Rebound metabolic acidosis following intentional amygdalin supplement overdose.
https://doi.org/10.1080/15563650.2019.1640369
Clinical Toxicology (Philadelphia, Pa.); Shively RM, Harding SA et. al.

Jul 19th, 2019 - Introduction: Amygdalin, marketed misleadingly as supplement "Vitamin B17," is a cyanogenic glycoside. When swallowed, it is hydrolyzed into cyanide in the small intestine, which causes histotoxic hypoxia via inhibition of cytochrome c oxidase. It...

Efficacy of Oral Administration of Sodium Thiosulfate and Glycine in a Large, Swine Mod...
https://doi.org/10.1016/j.annemergmed.2019.03.023
Annals of Emergency Medicine; Ng PC, Hendry-Hofer TB et. al.

May 13th, 2019 - Cyanide is a deadly poison, particularly with oral exposure, in which larger doses can occur before any symptoms develop. Multiple governmental agencies highlight oral cyanide as an agent that can be used in a terrorist attack because it can be ea...

Intramuscular sodium tetrathionate as an antidote in a clinically relevant swine model ...
https://doi.org/10.1080/15563650.2019.1602272
Clinical Toxicology (Philadelphia, Pa.); Hendry-Hofer TB, Witeof AE et. al.

Apr 21st, 2019 - Cyanide is a metabolic poison used in multiple industries and is a high threat chemical agent. Current antidotes require intravenous administration, limiting their usefulness in a mass casualty scenario. Sodium tetrathionate reacts directly with c...

Iatrogenic pediatric hydroxocobalamin overdose.
https://doi.org/10.1016/j.ajem.2019.04.012
The American Journal of Emergency Medicine; Friedman BT, Chen BC et. al.

Apr 19th, 2019 - Hydroxocobalamin, a precursor molecule to vitamin B12, has emerged as the preferred empiric treatment for patients rescued from enclosed-space fires with concern for inhalational injury and potential concomitant cyanide toxicity. Limited data exis...

see more →