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About 339 results

ALLMedicine™ Iron Toxicity Center

Research & Reviews  167 results

Hard as Iron: A Case of Delayed Presentation of Severe Iron Toxicity With Diagnostic an...
https://doi.org/10.1097/PEC.0000000000002430
Pediatric Emergency Care; Rickner SS, Feng SY

Apr 27th, 2021 - Cases of severe iron toxicity have become increasingly rare; most cases are intentional ingestions by late adolescents and adults who present within 12 hours of ingestion. We present a case of an adolescent girl with metabolic acidosis, hypoglycem...

Population genetic structure and association mapping for iron toxicity tolerance in rice.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7920388
PloS One; Pawar S, Pandit E et. al.

Mar 1st, 2021 - Iron (Fe) toxicity is a major abiotic stress which severely reduces rice yield in many countries of the world. Genetic variation for this stress tolerance exists in rice germplasms. Mapping of gene(s)/QTL controlling the stress tolerance and trans...

Novel mutations in ATP13A2 associated with mixed neurological presentations and iron to...
https://doi.org/10.1016/j.brainres.2020.147167
Brain Research; Kırımtay K, Temizci B et. al.

Oct 22nd, 2020 - Kufor-Rakeb Syndrome (KRS) is an autosomal recessive disease characterized by Parkinsonism, pyramidal signs, dementia, and supranuclear gaze palsy. KRS is caused by mutations in ATP13A2producing a transmembrane protein responsible for the regulati...

Potential amelioration of waterborne iron toxicity in channel catfish (Ictalurus puncta...
https://doi.org/10.1016/j.ecoenv.2020.111337
Ecotoxicology and Environmental Safety; Yadav AK, Sinha AK et. al.

Sep 26th, 2020 - Iron overload in water is a problem in many areas of the world, which could exert toxic effects on fish. To achieve maximum growth and overall fitness, iron induced toxicity must be alleviated. Therefore, this research was undertaken to investigat...

Iron Induces Cell Death and Strengthens the Efficacy of Antiandrogen Therapy in Prostat...
https://doi.org/10.1158/1078-0432.CCR-20-3182
Clinical Cancer Research : an Official Journal of the Ame... Bordini J, Morisi F et. al.

Sep 15th, 2020 - In search of novel strategies to improve the outcome of advanced prostate cancer, we considered that prostate cancer cells rearrange iron homeostasis, favoring iron uptake and proliferation. We exploited this adaptation by exposing prostate cancer...

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Clinicaltrials.gov  169 results

Hard as Iron: A Case of Delayed Presentation of Severe Iron Toxicity With Diagnostic an...
https://doi.org/10.1097/PEC.0000000000002430
Pediatric Emergency Care; Rickner SS, Feng SY

Apr 27th, 2021 - Cases of severe iron toxicity have become increasingly rare; most cases are intentional ingestions by late adolescents and adults who present within 12 hours of ingestion. We present a case of an adolescent girl with metabolic acidosis, hypoglycem...

Population genetic structure and association mapping for iron toxicity tolerance in rice.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7920388
PloS One; Pawar S, Pandit E et. al.

Mar 1st, 2021 - Iron (Fe) toxicity is a major abiotic stress which severely reduces rice yield in many countries of the world. Genetic variation for this stress tolerance exists in rice germplasms. Mapping of gene(s)/QTL controlling the stress tolerance and trans...

Novel mutations in ATP13A2 associated with mixed neurological presentations and iron to...
https://doi.org/10.1016/j.brainres.2020.147167
Brain Research; Kırımtay K, Temizci B et. al.

Oct 22nd, 2020 - Kufor-Rakeb Syndrome (KRS) is an autosomal recessive disease characterized by Parkinsonism, pyramidal signs, dementia, and supranuclear gaze palsy. KRS is caused by mutations in ATP13A2producing a transmembrane protein responsible for the regulati...

Potential amelioration of waterborne iron toxicity in channel catfish (Ictalurus puncta...
https://doi.org/10.1016/j.ecoenv.2020.111337
Ecotoxicology and Environmental Safety; Yadav AK, Sinha AK et. al.

Sep 26th, 2020 - Iron overload in water is a problem in many areas of the world, which could exert toxic effects on fish. To achieve maximum growth and overall fitness, iron induced toxicity must be alleviated. Therefore, this research was undertaken to investigat...

Iron Induces Cell Death and Strengthens the Efficacy of Antiandrogen Therapy in Prostat...
https://doi.org/10.1158/1078-0432.CCR-20-3182
Clinical Cancer Research : an Official Journal of the Ame... Bordini J, Morisi F et. al.

Sep 15th, 2020 - In search of novel strategies to improve the outcome of advanced prostate cancer, we considered that prostate cancer cells rearrange iron homeostasis, favoring iron uptake and proliferation. We exploited this adaptation by exposing prostate cancer...

see more →

News  3 results

Will We Make Artificial Blood Soon? (STAT)
https://www.medpagetoday.com/criticalcare/intensivists/63444

Feb 27th, 2017 - Researchers have sought a blood substitute for over 150 years, and they've all failed. Now, one candidate has demonstrated promising early results, while another nears clinical trials again, reported STAT. ErythroMer encloses hemoglobin in a synth...

Study challenges previous notions about RBC disposal
https://www.mdedge.com/hematology-oncology/article/187203/anemia/study-challenges-previous-notions-about-rbc-disposal
HT Staff

Jul 19th, 2016 - Red blood cells A new study contradicts previous beliefs about how the body disposes of red blood cells (RBCs) and recycles their iron. The work suggests the accumulation and removal of aged or damaged RBCs largely takes place in the liver rather.

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