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About 358 results

ALLMedicine™ Toxicology Center

Research & Reviews  175 results

Quantitative Systems Toxicology Modeling Predicts that Reduced Biliary Efflux Contribut...
https://doi.org/10.1002/cpt.2007
Clinical Pharmacology and Therapeutics; Beaudoin JJ, Brock WJ et. al.

Aug 2nd, 2020 - Patients with autosomal dominant polycystic kidney disease (ADPKD) exhibit enhanced susceptibility to tolvaptan hepatotoxicity relative to other patient populations. In a rodent model of ADPKD, the expression and function of the biliary efflux tra...

Use of computational toxicology (CompTox) tools to predict in vivo toxicity for risk as...
https://doi.org/10.1016/j.yrtph.2020.104724
Regulatory Toxicology and Pharmacology : RTP; Silva MH

Jul 8th, 2020 - Computational Toxicology tools were used to predict toxicity for three pesticides: propyzamide (PZ), carbaryl (CB) and chlorpyrifos (CPF). The tools used included: a) ToxCast/Tox21 assays (AC50 s μM: concentration 50% maximum activity); b) in vitr...

Measuring Reactive Sulfur Species and Thiol Oxidation States: Challenges and Cautions i...
https://doi.org/10.1089/ars.2020.8077
Antioxidants & Redox Signaling; Nagy P, Dóka É et. al.

Jul 7th, 2020 - Significance: Redox biology is gaining ground in research related to human physiology (metabolism, signaling), pathophysiology (cancer, cardiovascular disease, neurodegeneration), and toxicology (radiation- or xenobiotic-induced damage). A major h...

Characteristics of Transgender Patient Cases Managed by a Toxicologist: an Analysis of ...
https://doi.org/10.1007/s13181-020-00789-1
Journal of Medical Toxicology : Official Journal of the American College of Medical Toxicology; Surmaitis RM, Greenberg MR et. al.

Jun 16th, 2020 - The Toxicology Investigators Consortium (ToxIC) database, created in 2010 by the American College of Medical Toxicology (ACMT), compiles data recorded by medical toxicologists. In January 2017, the data field for transgender (and if transgender, m...

Measuring Intracellular Concentrations of Calcineurin Inhibitors: Expert Consensus from...
https://doi.org/10.1097/FTD.0000000000000780
Therapeutic Drug Monitoring; Lemaitre F, Vethe NT et. al.

Jun 10th, 2020 - Therapeutic drug monitoring (TDM) of the two calcineurin inhibitors (CNIs), tacrolimus (TAC) and cyclosporine A (CsA), has resulted in improvements in the management of patients who have undergone solid organ transplantation. As a result of TDM, a...

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Guidelines  3 results

ACMT Position Statement: Hospital Privileges for Physicians Practicing Medical Toxicology.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440314
Journal of Medical Toxicology : Official Journal of the American College of Medical Toxicology; American College Of Medical Toxicology

Aug 16th, 2016 - ACMT Position Statement: Hospital Privileges for Physicians Practicing Medical Toxicology.|2016|American College Of Medical Toxicology ,|standards,standards,standards,standards,standards,

ACMT Position Statement: The Use of Methadone as an Analgesic.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880609
Journal of Medical Toxicology : Official Journal of the American College of Medical Toxicology; American College Of Medical Toxicology

Jan 9th, 2016 - ACMT Position Statement: The Use of Methadone as an Analgesic.|2016|American College Of Medical Toxicology ,|adverse effects,therapeutic use,adverse effects,therapeutic use,standards,standards,

Scientific Working Group for Forensic Toxicology (SWGTOX) standard practices for method...
https://doi.org/10.1093/jat/bkt054
Journal of Analytical Toxicology;

Aug 12th, 2013 - Scientific Working Group for Forensic Toxicology (SWGTOX) standard practices for method validation in forensic toxicology.|2013| ,|methods,standards,analysis,

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Drugs  1 results see all →

Clinicaltrials.gov  179 results

Quantitative Systems Toxicology Modeling Predicts that Reduced Biliary Efflux Contribut...
https://doi.org/10.1002/cpt.2007
Clinical Pharmacology and Therapeutics; Beaudoin JJ, Brock WJ et. al.

Aug 2nd, 2020 - Patients with autosomal dominant polycystic kidney disease (ADPKD) exhibit enhanced susceptibility to tolvaptan hepatotoxicity relative to other patient populations. In a rodent model of ADPKD, the expression and function of the biliary efflux tra...

Use of computational toxicology (CompTox) tools to predict in vivo toxicity for risk as...
https://doi.org/10.1016/j.yrtph.2020.104724
Regulatory Toxicology and Pharmacology : RTP; Silva MH

Jul 8th, 2020 - Computational Toxicology tools were used to predict toxicity for three pesticides: propyzamide (PZ), carbaryl (CB) and chlorpyrifos (CPF). The tools used included: a) ToxCast/Tox21 assays (AC50 s μM: concentration 50% maximum activity); b) in vitr...

Measuring Reactive Sulfur Species and Thiol Oxidation States: Challenges and Cautions i...
https://doi.org/10.1089/ars.2020.8077
Antioxidants & Redox Signaling; Nagy P, Dóka É et. al.

Jul 7th, 2020 - Significance: Redox biology is gaining ground in research related to human physiology (metabolism, signaling), pathophysiology (cancer, cardiovascular disease, neurodegeneration), and toxicology (radiation- or xenobiotic-induced damage). A major h...

Characteristics of Transgender Patient Cases Managed by a Toxicologist: an Analysis of ...
https://doi.org/10.1007/s13181-020-00789-1
Journal of Medical Toxicology : Official Journal of the American College of Medical Toxicology; Surmaitis RM, Greenberg MR et. al.

Jun 16th, 2020 - The Toxicology Investigators Consortium (ToxIC) database, created in 2010 by the American College of Medical Toxicology (ACMT), compiles data recorded by medical toxicologists. In January 2017, the data field for transgender (and if transgender, m...

Measuring Intracellular Concentrations of Calcineurin Inhibitors: Expert Consensus from...
https://doi.org/10.1097/FTD.0000000000000780
Therapeutic Drug Monitoring; Lemaitre F, Vethe NT et. al.

Jun 10th, 2020 - Therapeutic drug monitoring (TDM) of the two calcineurin inhibitors (CNIs), tacrolimus (TAC) and cyclosporine A (CsA), has resulted in improvements in the management of patients who have undergone solid organ transplantation. As a result of TDM, a...

see more →