ALLMedicine™ Iron Toxicity Center
Research & Reviews 87 results
https://doi.org/10.1016/j.ejphar.2022.174981
European Journal of Pharmacology; Alikhani M, Aalikhani M et. al.
Apr 30th, 2022 - Iron-overload is one of the risk factors in susceptible individuals. Iron-overload causes complications such as diastolic dysfunction, arrhythmias, ventricular dilation, and systolic dysfunction in the heart. Therefore, particular care is needed f...
https://doi.org/10.1002/alz.056458
Alzheimer's & Dementia : the Journal of the Alzheimer's A... Nara PL
Feb 4th, 2022 - Alzheimer's disease (AD) is a progressive neuroinflammatory and neurodegenerative disease of the brain, defined by the accumulation and deposition of beta-amyloid, which has recently been identified as an antimicrobial peptide suggesting an infect...
https://doi.org/10.1002/hep.32270
Hepatology (Baltimore, Md.); Xiong H, Zhang C et. al.
Dec 7th, 2021 - Iron overload (IO) is a frequent finding in the general population. As the major iron storage site, the liver is subject to iron toxicity. Farnesoid X receptor (FXR) regulates bile acid metabolism and is implicated in various liver diseases. We ai...
https://doi.org/10.1016/j.brainresbull.2021.11.014
Brain Research Bulletin; Wei Y, Song X et. al.
Nov 29th, 2021 - Intracerebral hemorrhage (ICH)-induced brain injury is a continuous pathological process that involves the deterioration of neurological functions, such as sensory, cognitive or motor functions. Cytotoxic byproducts of red blood cell lysis, especi...
https://doi.org/10.1016/j.ecoenv.2021.112648
Ecotoxicology and Environmental Safety; Wang Q, Jin Q et. al.
Aug 28th, 2021 - Panax ginseng and Panax quinquefolius can survive for long periods of time in iron toxicity-stressed environments, which cause rusty roots and reduced productivity. To reveal the proteomic changes in these two Panax species in response to iron tox...
Clinicaltrials.gov 4 results
https://clinicaltrials.gov/ct2/show/NCT04947540
Jul 19th, 2021 - Thalassemia is derived from the Greek words, thals, which means sea, and emia, which means blood, signifying that it is more common in the Mediterranean region . Globally, among humans, thalassemia is the commonest single-gene disorder. It is defi...
https://clinicaltrials.gov/ct2/show/NCT03040765
Dec 12th, 2019 - Despite the significant improvements in the therapeutic management of beta thalassemia major (BTM) over the past few decades, osteoporosis is still a common finding, even in optimally treated patients. The relationships between bone mineral densit...
https://clinicaltrials.gov/ct2/show/NCT01284127
Sep 23rd, 2019 - First described over 100 years ago, superficial siderosis is a rare neurodegenerative disease caused by iron toxicity in the CNS due to chronic subarachnoid bleeding. Iron from red blood cells in the subarachnoid space is preferentially taken up b...
https://clinicaltrials.gov/ct2/show/NCT01376622
Jun 20th, 2011 - Despite continuing advances in iron chelation therapy, iron toxicity of endocrine glands, particularly the pituitary gland, remains common in patients with transfusion dependent anemias. We would like to establish accurate population norms of pitu...
News 2 results
https://www.medpagetoday.com/criticalcare/intensivists/63444
Feb 27th, 2017 - Researchers have sought a blood substitute for over 150 years, and they've all failed. Now, one candidate has demonstrated promising early results, while another nears clinical trials again, reported STAT. ErythroMer encloses hemoglobin in a synth...
https://www.medpagetoday.com/hematologyoncology/hematology/41120
Aug 21st, 2013 - Action Points Patients with hemochromatosis were taller on average than those in a reference population. The deviation in height did not correlate with the type of HFE mutation, serum ferritin level, liver enzyme elevation, liver fibrosis, or clin...